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Article Title Author (First author listed first | format: Last Name First Name) Publication Year Study Type Content Type Peer Reviewed? Intervention Summary Population: > Age 65 Population: < Age 65 Population: Chronic Condition Population: Chronic Condition 2 Population: Chronic Condition 3 Outcome Type Outcome Description Journal Search Site PMID DOI Hyperlink
Comparative Evaluation of Boenninghausen’s and Kent’s Repertory in The Management of Chronic Migraine: A Multi-Centric Clinical Study Shaikh, MAS; Kanchar, AG; Tiwari, SU 2025 Other Linking Intervention and Impact No Prospective comparative study in 60 migraine patients at two centres in Maharashtra: prescriptions derived using Boenninghausen's Therapeutic Pocket Book vs Kent's Repertory, followed over 12 weeks Yes Neurologic Disorders Favorable Both groups improved over 12 weeks: mean attack frequency fell from 6.3 +/- 1.2 to 2.8 +/- 0.9 with Boenninghausen's repertory and from 6.1 +/- 1.0 to 3.6 +/- 1.1 with Kent's, with MIDAS scores improving 65% and 48% respectively. Zenodo repository deposit - no journal identified Google Scholar 10.5281/zenodo.17481418 https://zenodo.org/records/17481418
Usefulness of Individualized Homeopathy versus Standard Allopathic Treatment in Acute Uncomplicated Urinary Tract Infection (UTI): A Randomized Comparative Trial Singh, D; Gilla, D; Kundu, C; Wadhwa, B; Oberai, P; Kumari, D; Bajpai, A 2026 RCT Linking Intervention and Impact Yes Multicentric open-label randomized trial in 70 patients aged 18-60 with acute uncomplicated urinary tract infection: individualized homeopathy vs standard allopathic treatment including antibiotics No Yes Favorable UTISA severity fell comparably in both arms by day 10, with homeopathy showing greater early symptom reduction (51% vs 38% by day 3) and lower 6-month recurrence (17.65% vs 37.5%); microbiologic success by day 10 was higher in the allopathic arm. Homeopathy Google Scholar 10.1055/s-0046-1817091 https://www.thieme-connect.com/products/ejournals/abstract/10.1055/s-0046-1817091
Effect of Periodontal Therapy on Hba1c Levels of Type II Diabetic Patients-A Systematic Review Abueida, M; Reddy, MS; Kukreja, BJ; SR, S; Sayed, MAA; Dsouza, J; Abdelmagyd, HAE 2025 Systematic Review Linking Intervention and Impact Yes Systematic review of 18 RCTs (1,315 patients) on the effect of nonsurgical periodontal therapy on glycated hemoglobin in type 2 diabetes, with HbA1c at 3 and 6 months Yes Diabetes Favorable HbA1c fell by 1.16 +/- 1.90 at 3 months and 1.45 +/- 2.22 at 6 months, with a significantly greater reduction at 6 months than at 3 months and multiple sessions of nonsurgical periodontal therapy showing greater impact. The authors note these results contrast with previous systematic reviews. Journal of International Dental and Medical Research Google Scholar https://nchr.elsevierpure.com/en/publications/effect-of-periodontal-therapy-on-hba1c-levels-of-type-ii-diabetic/
Clinical Improvement of Vitiligo following Individualized Homoeopathic Management: A Case Report Sarkar, T; Das, B; Panja, K; Islam, MS 2026 Case Study Linking Intervention and Impact Case report of a 15-year-old male with a hypopigmented vitiligo patch on the left cheek, treated with individualized homoeopathy (Natrum muriaticum in centesimal potency) and followed for three months. Improvement was assessed using the Vitiligo Area Scoring Index and clinical photography, with the modified Naranjo criteria for homeopathy (MONARCH) applied to assess causal attribution. No Yes Autoimmune Disease Favorable Objective improvement in Vitiligo Area Scoring Index was verified over three months alongside clinical photography, with the MONARCH framework used to establish the causal relationship between improvement and the intervention. Indian Journal of Integrative Medicine Google Scholar https://mansapublishers.com/ijim/article/view/8065
Reflections on the role of music therapy in lung cancer care Meng, C; Teng, W 2025 Meta Analysis Linking Intervention and Impact Yes Systematic review and meta-analysis of 16 RCTs (1,991 lung cancer patients) on music therapy for anxiety, depression, pain, sleep quality and quality of life. Seven databases searched to 31 December 2023, quality assessed with Cochrane Risk of Bias and certainty with GRADE. Yes Cancer Favorable Versus routine treatment, music therapy reduced anxiety (SMD -1.43), depression (SMD -1.49) and pain (SMD -1.58) and improved sleep quality (MD -3.02) and quality of life (SMD 1.50). Authors report 30 minutes once or twice daily over 2 weeks to 3 months may alleviate anxiety most effectively. Supportive Care in Cancer Google Scholar 10.1007/s00520-025-09213-2 https://link.springer.com/article/10.1007/s00520-025-09213-2
The Application of Foot Exercises in Reducing Blood Sugar Levels in Type II Diabetes Mellitus Patients Fakruddin, F; Alfiandi, R 2025 Case Study Linking Intervention and Impact Descriptive case study of two patients with type 2 diabetes in the UPTD working area of Ulee Kareng Health Center, Banda Aceh, from 23 to 27 December 2024. Foot exercise therapy was delivered once daily for five consecutive days in 30-minute sessions, with blood glucose measured by glucometer. Yes Diabetes Favorable Blood sugar fell from 295 to 230 mg/dl in the first subject and from 317 to 197 mg/dl in the second over five days. Jurnal Akademik Keperawatan Google Scholar https://jurnals.akimba.ac.id/index.php/juka/article/view/197
Effect of electroacupuncture combined with Tuina therapy on gut microbiota in patients with knee osteoarthritis Guo, X; Guo, L; Lu, QZ; Xie, H; Chen, J; Su, WL; Tian, Y; Li, XH; Miao, HL; Zhang, Y 2025 RCT Linking Intervention and Impact Yes RCT in 60 patients with knee osteoarthritis: electroacupuncture alone vs electroacupuncture plus Tuina (n=30 each), 12 sessions, with faecal 16S rRNA sequencing before and after Yes Favorable The combined group had higher effective response rates and significantly lower VAS than electroacupuncture alone immediately and at one week (p<0.001), with improved total WOMAC, stiffness and function but no significant change in the WOMAC pain subscale. Gut microbiota beta diversity shifted in the combined group only. World Journal of Gastroenterology Google Scholar 40496364 https://www.wjgnet.com/1007-9327/full/v31/i18/105495.htm
Neurotherapy as a Complementary Approach for Beta-Thalassemia Intermedia Dutta, P; Dev, D 2025 Case Study Linking Intervention and Impact Yes Case report of a 44-year-old woman with beta-thalassemia intermedia who underwent 48 neurotherapy sessions over three months, applying pressure points intended to stimulate pancreas, kidney, thyroid and liver function No Yes Favorable Haemoglobin rose from 5.9 to 9.7 g/dL, with improvements in haematocrit, MCV, MCH, MCHC and ferritin, reductions in platelets, serum TSH and ESR, and normalised vitamin B12. The patient reported increased energy, reduced fatigue and improved activity tolerance, with no adverse effects observed. Nigerian Medical Journal Google Scholar 40703874 https://pmc.ncbi.nlm.nih.gov/articles/PMC12280303/
Effectiveness of acupuncture and laser acupuncture in combination with dietary therapy and exercise for overweight and obese women: a randomized trial Shojaedin, A; Laal, N; Sheibani, F; Razzaghi, Z; Abolhasani, M; Zayeri, F 2025 RCT Linking Intervention and Impact Yes Four-arm randomized trial in 100 women aged 18-50 with BMI 25-39.9: diet and exercise alone, or with acupuncture, laser acupuncture, or both, assessed to three months post-intervention No Yes Favorable All four groups significantly reduced BMI and fat mass. Only the combined acupuncture-plus-laser-acupuncture group achieved greater fat mass reduction than diet and exercise alone; acupuncture alone and laser acupuncture alone were not significantly different from the diet group. Innovations in Acupuncture and Medicine Google Scholar 10.1186/s44424-025-00009-z https://link.springer.com/article/10.1186/s44424-025-00009-z
A Case Report and Follow-up Study on Myofascial Release of Posterior Chain Muscles for Chronic Sinus Headache Nithisha, G; Gurudut, P; Welling, A; Kage, V 2025 Case Study Linking Intervention and Impact Yes Case report with follow-up of a 40-year-old woman with chronic sinus headache treated by myofascial release of the posterior chain muscles combined with a manual drainage technique, as a complement to medical management. No Yes Favorable The patient showed major improvements in headache intensity and frequency and enhanced quality of life. The authors call for controlled trials to validate the findings. International Journal of Therapeutic Massage & Bodywork Google Scholar 41356773 https://pmc.ncbi.nlm.nih.gov/articles/PMC12677952/
Wet Cupping Therapy as A Complementary Intervention for Blood Glucose Reduction: Pre-Experimental Study Mahfud, M; Sarwadhamana, RJ; Muhammad, DF; Almubarok, AZ; Arroyan, A 2026 Other Linking Intervention and Impact Single-group pre-post study of one wet cupping session in 30 adults aged 26-45 not taking glucose-lowering medication, Yogyakarta, Indonesia No Yes Favorable Mean blood glucose fell from 131 mg/dL before the intervention to 117 mg/dL immediately after, a reduction of 14.2 mg/dL (p = 0.0001). Berita Ilmu Keperawatan Google Scholar https://journals2.ums.ac.id/bik/article/view/12526
The Effect of Autogenic Relaxation Therapy Combined with Mozart Music on Blood Pressure Reduction in Hypertensive Patients: A Quasi-Experimental Study Ropei, O; Tamin, S; Kumala, TF; Fitri, R 2025 Other Linking Intervention and Impact One-group pretest-posttest study in 36 patients with primary hypertension: autogenic relaxation therapy with Mozart music, 15-20 minutes daily for three consecutive days Yes Cardiovascular Disorders Favorable Mean systolic pressure fell from 144.17 to 126.67 mmHg and diastolic from 90.56 to 82.22 mmHg, both p<0.001. Jurnal Keperawatan PPNI Jawa Barat Google Scholar https://ppnijabar.or.id/ojs/index.php/jkp/article/view/36
Acupressure Self-Care as a Complementary Therapy to Manage Hypertension Kristanti, RS; Arsa, SAW; Wulandari, NA 2025 Other Linking Intervention and Impact Community program with an Indonesian gymnastics group: 36 participants received education and training in self-administered acupressure, with blood pressure, knowledge and skills assessed before and after Yes Cardiovascular Disorders Favorable Reports significant reductions in systolic and diastolic blood pressure following the program, alongside increased knowledge and skills, with participants able to demonstrate acupressure points and techniques for hypertension. Journal of Community Research and Engagement Google Scholar 10.38040/jcore.v2i2.1295 https://jurnal.umla.ac.id/index.php/JCRE/article/view/1295
Acupuncture in the treatment of fibromyalgia: An updated review of clinical evidence De Carvalho, JF; Viterbo, W 2026 Other Linking Intervention and Impact Narrative review of acupuncture for fibromyalgia covering 23 RCTs and 11 systematic reviews/meta-analyses (over 8,400 participants across 15 countries) Yes Favorable Acupuncture significantly reduced pain and improved quality of life and emotional symptoms versus usual care or sham, with a small-to-moderate effect size and rare, mild adverse events. EULAR treats acupuncture as optional while recent Chinese guidelines give it a strong recommendation. Journal of Homeopathy Studies Google Scholar https://www.homeopathyjournal.com/archives/2026.v3.i1.A.32/acupuncture-in-the-treatment-of-fibromyalgia-an-updated-review-of-clinical-evidence
Siddha Varma Stimulation as a Non-Pharmacological Strategy for Insomnia: Clinical Evaluation of Kothandaadangal Points Shilpa, K; Rajarajeswari, T; Bernaitis, L 2025 Prosp Cohort Study Linking Intervention and Impact Prospective observational single-arm study in 20 participants aged 25-60 with primary insomnia diagnosed by ICSD-3 criteria, receiving Kothandaadangal Varma point stimulation three times weekly for six weeks. Sleep assessed by Insomnia Severity Index and self-reported sleep diaries. No Yes Favorable Insomnia Severity Index fell from a baseline mean of 22.5 to 11.2, sleep latency from 60 to 25 minutes, and average total sleep time rose from 4.2 to 6.8 hours, with no adverse effects reported. World Journal of Multidisciplinary Studies Google Scholar https://wasrpublication.com/index.php/wjms/article/view/116
Pain, Oedema and Trismus Responses Following Photobiomodulation Therapy Immediately After Lower Third Molar Extraction: Results of a Randomized, Double-Blind and Split-Mouth Clinical Trial Camolesi, GCV; El Kattan, AS; Lopez-Lopez, J; Blanco-Carrión, A; García-García, A; Gándara-Vila, P; Pérez-Sayáns, M 2025 RCT Linking Intervention and Impact Yes Randomized, double-blind, split-mouth trial in 83 patients after bilateral lower third molar extraction: a single 30-second postoperative photobiomodulation session (808 nm diode laser) on one side vs simulated laser on the other Yes Favorable Significant pain reduction at all evaluation times (P<.01), with reduced facial oedema and trismus on postoperative days 2 and 7 (P<.01) and lower analgesic consumption on all days except the seventh. Journal of Evidence-Based Dental Practice Google Scholar 10.1016/j.jebdp.2024.102080 https://www.sciencedirect.com/science/article/pii/S1532338224001301
Enhancing Sleep Quality in Hypertensive Patients Through Slow Stroke Back Massage: A Family Nursing Care Approach Arista, AN; Minarti, M; Norontoko, DA; Novitasari, A 2026 Case Study Linking Intervention and Impact Descriptive case study of two elderly hypertensive patients receiving family nursing care at Puskesmas Tambak Wedi, Surabaya. Slow Stroke Back Massage was performed for 30 minutes every two days over one week, with data collected by observation, interview and the Pittsburgh Sleep Quality Index. Yes No Cardiovascular Disorders Favorable Both patients improved on the Pittsburgh Sleep Quality Index (14 to 5 and 16 to 6) alongside better blood pressure control. The authors state the findings describe individual improvements in two cases and are not generalizable. International Journal of Nursing and Health Services Google Scholar https://www.ijnhs.net/index.php/ijnhs/article/view/892
Efficacy of Homeopathic Remedies in the Treatment of Chronic Skin Disorders: A Multicenter Study Tayal, I 2026 Case Study Linking Intervention and Impact Case-based study of patients with chronic skin disorders (eczema, psoriasis, acne, dermatitis) treated with individualized homeopathic remedies selected on physical, emotional and constitutional characteristics Yes Favorable Reports noticeable improvement in skin conditions, with reduced symptom severity and decreased recurrence among patients receiving individualized homeopathic treatment. Cadernos de Pos-Graduacao em Direito Politico e Economico Google Scholar https://ceapress.org/index.php/cpgdpe/article/view/224
Efficacy of Individualized Homoeopathic Medicines in Alcohol Addiction: A Retrospective Observational Study Using AUDIT Scores Puri, V; Munjal, S 2025 Other Linking Intervention and Impact Retrospective observational study of 40 adults with alcohol use disorder treated with individualized homoeopathic medicines (2021-2023), with AUDIT scores at baseline, 6 and 12 months Yes Alcohol/Drug Dependence Favorable AUDIT scores fell from 27.1 +/- 4.5 at baseline to 17.3 +/- 3.9 at 6 months and 11.2 +/- 3.2 at 12 months (p<0.001), with a large effect size (Cohen's d = 2.6) and no major adverse effects; 36 of 40 patients completed follow-up and intention-to-treat analysis showed similar directional improvement. Indian Journal of Integrative Medicine Google Scholar https://mansapublishers.com/ijim/article/view/7820
Comparison of Adjunctive Homeopathy with Adjunctive Allopathy in Non-Surgical Periodontal Treatment of Patients with Chronic Periodontitis: A Randomized Study Chaudhary, A; Dighe, L; Bhatt, P; Pandey, S 2026 RCT Linking Intervention and Impact Yes Open-label randomized two-arm study in 54 analysed patients with mild-to-moderate chronic periodontitis: 9 months of adjunctive individualized homeopathy vs adjunctive allopathic treatment after non-surgical periodontal therapy No Yes Neutral Both arms improved in clinical attachment loss with no significant difference (45.84% reduction with homeopathy vs 42.56% with allopathy, p=0.798) and 77% OHAT improvement in both. The homeopathy arm required no anti-inflammatories or antiseptics. Homeopathy Google Scholar 10.1055/s-0046-1817104 https://www.thieme-connect.com/products/ejournals/abstract/10.1055/s-0046-1817104?lang=en
Effectiveness of individualized homeopathic medicine for reducing tobacco dependence in age group of 18-60 years-A case series. Nimbhore, G; Yadav, S; Valke, A; Nair, S; Rohom, S; Shaikh, F; Naaz, MS; Yashwant, MV 2025 Case Study Linking Intervention and Impact Case series of 30 subjects aged 18-60 with tobacco dependence given individualized homoeopathic medicine, with dependence measured by the Fagerstrom Test No Yes Alcohol/Drug Dependence Favorable Improvement was reported in 26 of 30 patients (86.66%), with frequency and dependency unchanged in 4 (13.33%). Paired t-tests gave t values of 10.16 for dependency and 7.15 for frequency of tobacco consumed per day. Materia Novum: The Journal of Homoeopathy Google Scholar https://journal.mhmc.org.in/articles/MNH490002
Individualized Homeopathic Medicines as Adjunctive to Standard Care for Improving Symptoms of Peripheral Diabetic Neuropathy in Middle-Aged Individuals: Double Blind, Randomized, Placebo-Controlled Trial Chandra, S; Pal, RK; Saha, S; Koley, M; Mandal, G; Midya, A; De, S; Biswas, S; Chakraborty, D; Ghosh, S 2026 RCT Linking Intervention and Impact Yes Three-month double-blind, placebo-controlled trial in 116 participants with peripheral diabetic neuropathy: individualized homeopathic medicinal products vs identical placebos, both alongside standard diabetic care Yes Diabetes Neurologic Disorders Favorable All outcomes favoured individualized homeopathy over placebo: NTSS-6, DN4, SF-MPQ total and DNE (all p<0.001) plus HbA1c (p<0.001, d=1.47). Most frequently used remedies were Sulphur (27.1%), Natrum muriaticum and Lycopodium clavatum. Homeopathy Google Scholar 10.1055/s-0046-1817101 https://www.thieme-connect.de/products/ejournals/abstract/10.1055/s-0046-1817101
Clinical outcome of homeopathic treatment in hypothyroidism: A case report Patil, SS; Bodkhe, SD; Fule, P 2026 Case Study Linking Intervention and Impact Case report of a 34-year-old woman with hypothyroidism presenting with weight gain, fatigue, constipation, hair fall and cold intolerance alongside elevated TSH, treated with an individualized homeopathic remedy and followed over eight months. No Yes Favorable Gradual improvement in clinical symptoms alongside normalization of thyroid function tests, with symptomatic relief and no adverse effects reported over eight months of follow-up. International Journal of Advanced Academic Studies Google Scholar https://www.allstudyjournal.com/archives/2026.v8.i1.B.1820
HPTLC characterization of Tinospora cordifolia (Guduchi/Giloy) mother tincture and a randomized clinical comparison with individualized homeopathic medicines in adults with type 2 diabetes mellitus: Tinospora cordifolia in diabetes mellitus Goenka, R; Sadhukhan, S; Midya, A; Koley, M; Saha, S 2026 RCT Linking Intervention and Impact Yes Open-label randomized pragmatic trial over 3 months in 60 adults with type 2 diabetes: Tinospora cordifolia mother tincture vs individualized homeopathic medicines, both with standardized diet and lifestyle advice Yes Diabetes Favorable Tinospora cordifolia mother tincture outperformed individualized homeopathic medicines on HbA1c (MD -1.3, p=0.006), fasting blood sugar (p=0.007) and post-prandial blood sugar (p=0.003). Secondary outcomes showed non-significant trends, non-inferiority was not demonstrated, and no adverse events occurred. Indian Journal of Traditional Knowledge Google Scholar https://or.niscpr.res.in/index.php/IJTK/article/view/17247
Effects of Mawangdui exercise intervention on the pulmonary function, physical fitness and quality of life in stable chronic obstructive pulmonary disease patients: a randomised controlled trial Zhu, Z; Muhamad, AS; Omar, N; Ooi, FK; Pan, X; Ong, MLY 2025 RCT Linking Intervention and Impact Yes RCT in 54 patients with stable mild-to-moderate COPD: 12 weeks of Mawangdui exercise, a low-to-medium-intensity traditional Chinese aerobic practice, vs control maintaining daily activities Yes Favorable At 12 weeks the Mawangdui group improved on Borg CR-10, SpO2, BMI, body fat, flexibility, mMRC and SGRQ (p<0.05), with 6-minute walk distance up 63.39 m and CAT dyspnoea down 5.50 points. FEV1, FVC and fat-free mass showed no improvement. Complementary Therapies in Medicine Google Scholar 10.1016/j.ctim.2025.103152 https://www.sciencedirect.com/science/article/pii/S0965229925000275
Online unsupervised Tai Chi intervention for people with knee osteoarthritis Zhu, S 2025 RCT Linking Intervention and Impact Yes 2-group RCT (RETREAT; 170 adults >=45 with knee OA) of a 12-week unsupervised video-based online Yang-style Tai Chi program vs online OA education control; knee pain and function. Yes Yes Favorable The unsupervised online Tai Chi program improved knee pain and function vs education control at 12 weeks, with more participants achieving clinically important improvements, plus gains in quality of life and balance confidence. JAMA Internal Medicine Google Scholar 10.1001/jamainternmed.2025.5723 https://jamanetwork.com/journals/jamainternalmedicine/article-abstract/2840563
Home-based traditional Chinese exercise for knee osteoarthritis: a systematic review and meta-analysis of randomized controlled trials Wang, W; Lu, H; Yan, C; Shan, Y 2025 Meta Analysis Linking Intervention and Impact Yes Systematic review / meta-analysis of 11 RCTs (854 participants) on home-based traditional Chinese exercise (Tai Chi, Baduanjin, Yijinjing, Wuqinxi) for knee osteoarthritis. Yes Yes Favorable Home-based traditional Chinese exercise significantly improved knee function (SMD -0.61), pain (-0.52), physical quality of life, and depression (-1.00), with minimal adverse events. Frontiers in Medicine Google Scholar 10.3389/fmed.2025.1665680 https://www.frontiersin.org/journals/medicine/articles/10.3389/fmed.2025.1665680/full
Effectiveness of alternative exercises in cardiac rehabilitation for program completion and outcomes in women with or at high risk of cardiovascular disease: a systematic review and meta-analysis Suebkinorn, O; Ramos, JS; Grace, SL; Gebremichael, LG; Bulamu, NB; de Plaza, MAP; Dafny, HA; Pearson, V; Bulto, LN; Chen, RT 2025 Meta Analysis Linking Intervention and Impact Yes Meta-analysis of 8 RCTs (398 women) of alternative exercises in cardiac rehabilitation (yoga, tai chi, stepping, Nordic walking, aerobic dance) vs gym-based exercise, education only or usual care Yes Cardiovascular Disorders Unfavorable The primary outcome, cardiac rehabilitation completion, showed little to no effect (RR 1.02; 2 trials, 51 participants). Possible short-term gains in blood pressure, weight and 6-minute walk test, but little to no effect on BMI, lipids, glucose, HbA1c, peak oxygen uptake, quality of life or depression. Certainty was very low throughout. JBI Evidence Synthesis Google Scholar https://cris.maastrichtuniversity.nl/en/publications/effectiveness-of-alternative-exercises-in-cardiac-rehabilitation-/
Effects of Different Exercise Types on Fall Efficacy in the Elderly: a Network Meta-analysis Zhang, L; Huang, S; Xu, H; Mei, H; Hong, Y 2025 Meta Analysis Linking Intervention and Impact Yes Network meta-analysis of 35 studies (2,627 participants, 13 exercise types) comparing exercise modalities for fall efficacy, balance and mobility in older adults. Ten databases searched to August 2025, Cochrane risk-of-bias appraisal, analysed in Stata 18 with SUCRA ranking of treatments. Yes No Favorable Tai Chi improved fall efficacy versus usual care (MD 9.24) and ranked most likely best (SUCRA 81.2), and was highest ranked for mobility (MD 4.44, SUCRA 95.0) and effective for balance (MD 3.87). Otago exercise performed comparably and ranked highest for balance. Chinese General Practice Google Scholar 10.12114/j.issn.1007-9572.2025.0224 https://www.chinagp.net/EN/10.12114/j.issn.1007-9572.2025.0224
The effects and optimal dosage of traditional Chinese exercises on patients with chronic ankle instability: A systematic review and meta-analysis Yin, Y; Lin, Q; Liu, Y 2025 Meta Analysis Linking Intervention and Impact Yes Systematic review and meta-analysis of 12 RCTs (323 patients) on traditional Chinese exercises for chronic ankle instability, searching eleven databases to January 2025, with PEDro quality appraisal, GRADE certainty rating, dosage subgroup analysis, and PROSPERO registration (CRD42024613359). Yes Favorable Significant improvements versus control in Cumberland Ankle Instability Tool score (WMD 4.02), balance across four directions (SMD 0.38-0.80), joint position sense and muscle strength. GRADE certainty was moderate for balance. Optimal dosage was Tai Chi twice weekly in 60-minute sessions over 12 weeks. Complementary Therapies in Medicine Google Scholar 10.1016/j.ctim.2025.103145 https://www.sciencedirect.com/science/article/pii/S0965229925000202
Benefits of Complementary Therapy Through Telemedicine Support in Palliative Care of Breast Cancer: Synergy of Pain Management and Psychological Support on Quality of Life Khamid, A; Susanti, I; Maulidia, DP; Safitri, ENN; Nabilla, CK; Febrianti, ANR; Firmansah, F; Rahmadina, A; Nurseha, H; Ramadhan, EAM 2026 Systematic Review Linking Intervention and Impact Systematic review following PRISMA guidelines of complementary therapies (acupuncture, yoga, music therapy) with telemedicine support in palliative care for breast cancer, covering studies published 2020-2024 and assessing pain and psychological well-being. Yes Cancer Favorable Review reports complementary therapies significantly reduced pain intensity, anxiety and depression and improved overall quality of life in breast cancer palliative care. Hearty: Jurnal Kesehatan Masyarakat Google Scholar https://ejournal.uika-bogor.ac.id/index.php/Hearty/article/view/19161
Statistical assessment of Indian classical music’s role in diabetes, thyroid, hypertension management Pingle, YP; Ragha, LK 2025 RCT Linking Intervention and Impact Yes Multi-centre RCT of Indian classical music (Raga Therapy) as an adjunct to standard treatment for diabetes, thyroid disorders and hypertension, using condition-specific ragas Yes Diabetes Cardiovascular Disorders Favorable Authors report significant health improvements among patients who integrated Raga Therapy into standard care for diabetes, thyroid disorders and hypertension. International Journal of Information Technology Google Scholar 10.1007/s41870-024-02227-9 https://link.springer.com/article/10.1007/s41870-024-02227-9
Complementary therapies for women with premature ovarian insufficiency: a systematic literature review to inform the 2024 update of the ESHRE/ASRM/IMS/CRE-WHiRL guidelines on premature ovarian insufficiency Maunder, A; Vermeulen, N; Vincent, AJ; Panay, N; Ee, C 2026 Systematic Review Linking Intervention and Impact Yes Systematic review of nine studies commissioned to inform the 2024 ESHRE/ASRM/IMS/CRE-WHiRL guidelines on complementary therapies for premature ovarian insufficiency Yes Neutral Chinese herbal medicine and acupuncture may alleviate menopausal symptoms, but evidence is very limited and of very low quality; adding acupuncture to hormone therapy gave no benefit and evidence was insufficient for all other therapies. The guideline concludes they should not replace hormone therapy. Climacteric Google Scholar 40719542 10.1080/13697137.2025.2530441 https://pubmed.ncbi.nlm.nih.gov/40719542/
Acupressure therapy for reducing blood pressure in elderly with hypertension Wahyuningsih, DA; Astuti, RT; Amin, MK; Pinilih, SS 2025 Case Study Linking Intervention and Impact Nursing case report of acupressure therapy applied at points LI4 (Hegu), GV20 (Baihui), GB20 (Fengchi) and GB21 (Jianjing) for an elderly inpatient with hypertension and anxiety, delivered at Tidar Regional Hospital, Magelang, Indonesia. Yes No Cardiovascular Disorders Mental Health Favorable Author reports a significant reduction in both anxiety and blood pressure in the client following acupressure therapy. International Conference of Advancements in Nursing Care Google Scholar https://journal.unimma.ac.id/index.php/ADNURS/article/view/14347
The Effect of Effleurage Massage on Anxiety in Pregnant Women Facing Childbirth Rukmawati, S; Nurhayati, R; Fatimah, NA 2025 Other Linking Intervention and Impact Pre-post control group study of effleurage massage (three 20-minute sessions weekly for four weeks) vs standard antenatal care in third-trimester pregnant women No Yes Mental Health Favorable Anxiety fell significantly in the intervention group from baseline to post-intervention (p<0.001) while the control group's anxiety increased (p=0.042), with a significant between-group difference after the intervention (p<0.001). Proceeding Strada International Conference on Health Google Scholar https://proceeding.thesich.org/index.php/sich/article/view/44
Effect of Foot Massage Therapy on Fatigue Level of Chronic Kidney Failure Patients Undergoing Hemodialysis: A Rapid Review Karisa, P; Bahlail, R; Nugraha, BA; Sutianingsih, T 2025 Systematic Review Linking Intervention and Impact Rapid review of seven RCTs and quasi-experimental studies (2018-2023) of foot massage therapy for fatigue in adults with chronic renal failure on hemodialysis Yes Favorable All seven included studies found massage therapy reduced fatigue in hemodialysis patients, with effective protocols ranging from 15-60 minutes, two to three times weekly, over three to nine weeks. Indonesian Nursing Journal of Education and Clinic Google Scholar 10.24990/injec.v10i2.658 https://injec.aipni-ainec.org/index.php/INJEC/article/view/658
The effectiveness of hypnotherapy in reducing stress among individuals with mental health disorders: A quasi-experimental study with a control group Ruswadi, I; Wennie, J; Susiani, A; Masliha, M 2025 Other Linking Intervention and Impact Pretest-posttest control group study in 80 participants with psychiatric disorders: six individual hypnotherapy sessions over four weeks vs standard psychiatric care Yes Mental Health Favorable Hypnotherapy produced significantly greater reductions than control in stress (MD -8.4, p<0.001) and anxiety (MD -7.4, p<0.001), both with large effect sizes (d>0.8), and 90% of the intervention group reported high satisfaction. Berita Ilmu Keperawatan Google Scholar https://journals2.ums.ac.id/index.php/bik/article/view/9806
Complementary Therapies To Reduce Fatigue In Hemodialysis Patients: A Scoping Review Of Randomized Controlled Trials Bahri, SH; Mardiyaningsih, E 2025 Systematic Review Linking Intervention and Impact Scoping review following JBI and PRISMA-ScR guidelines of complementary therapies for fatigue in hemodialysis patients aged 18 and over, covering RCTs published 2020-2025. Five databases searched; 3,355 articles identified and eight included, analysed by thematic synthesis. Yes Favorable Six intervention types were consistently effective for fatigue reduction (p<0.05) with improved psychological well-being: intradialytic exercise, olive oil massage, acupressure with Qur'anic recitation, relaxation techniques, humour therapy, and digital recreational therapy. Borneo Nursing Journal Google Scholar https://bnj.akys.ac.id/BNJ/article/view/442
Acupuncture as a Complementary Therapy for Stroke Risk Reduction in Rheumatoid Arthritis Torhild, HJ; Carlet, K; Torhild, LJ 2025 Other Linking Intervention and Impact Mixed-methods single-arm study of 200 rheumatoid arthritis patients aged 18-75 receiving regular acupuncture across three Norwegian cities, with interviews alongside biomarker assessment Yes Autoimmune Disease Cardiovascular Disorders Favorable Authors report significant reductions in inflammatory markers (CRP, TNF-alpha) and improved blood pressure regulation following acupuncture, with participants also reporting improved quality of life. Journal of Advances in Medicine and Pharmaceutical Sciences Google Scholar 10.36079/lamintang.jamaps-0401.818 https://lamintang.org/journal/index.php/jamaps/article/view/818
Murottal therapy to reduce anxiety in patient with appendicitis Wijiastuti, H; Handayani, E; Subrata, SA; Masithoh, RF 2026 Case Study Linking Intervention and Impact Nursing case study of a 43-year-old woman with appendicitis and preoperative anxiety given murottal therapy (Quranic recitation) for three consecutive days in 15-minute sessions No Yes Mental Health Favorable HARS scores decreased, vital signs improved, and the patient reported greater comfort and readiness for surgery. International Conference of Advancements in Nursing Care Google Scholar https://journal.unimma.ac.id/ADNURS/article/view/14364/
Effect of traditional Chinese exercise on older patients with diabetes mellitus: a systematic review and meta-analysis of randomized controlled trials Liu, W; Che, CC; Chui, PL; Ma, Z; Chen, J 2025 Meta Analysis Linking Intervention and Impact Yes Systematic review/meta-analysis of 11 RCTs (944 older diabetes patients) on traditional Chinese exercises (Tai Chi, Baduanjin, etc.) for blood glucose, HbA1c, BMI, and quality of life. Yes Yes Diabetes Favorable Traditional Chinese exercises reduced fasting blood glucose, HbA1c, and BMI and improved health-related quality of life in older diabetes patients; Baduanjin appeared particularly beneficial. Frontiers in Endocrinology Google Scholar 10.3389/fendo.2025.1499051 https://www.frontiersin.org/journals/endocrinology/articles/10.3389/fendo.2025.1499051/full
Effects of photobiomodulation on multiple health outcomes: an umbrella review of randomized clinical trials Son, Y; Lee, H; Yu, S; Kim, HJ; Park, J; Woo, S; Lee, H; Fond, G; Boyer, L; Rahmati, M 2025 Systematic Review Linking Intervention and Impact Yes Umbrella review of 15 meta-analyses covering 204 RCTs and over 9,000 participants on photobiomodulation (low-level light therapy) across 35 health endpoints in 15 conditions Yes Favorable Significant effects for 12 of 35 endpoints, with moderate certainty for burning mouth syndrome pain (eSMD -0.92), knee osteoarthritis disability, fibromyalgia fatigue, hair density and cognitive function. Most remaining outcomes were low or very low certainty; authors advise against widespread adoption pending higher-quality trials. Systematic Reviews Google Scholar 40770824 https://pubmed.ncbi.nlm.nih.gov/40770824/
Combination of Music Therapy and Progressive Muscle Relaxation in Patients with Hypertension: A Case Study Iskandar, A; Pratama, KN; Yulianto, P 2026 Case Study Linking Intervention and Impact Case study of three women aged 60-74 with essential hypertension and not taking antihypertensive medication, receiving combined music therapy and progressive muscle relaxation. Systolic and diastolic blood pressure were measured before and after the intervention alongside qualitative observation. Yes Yes Cardiovascular Disorders Favorable Mean systolic pressure fell 9.11 mmHg (range 2-14) and diastolic 6.11 mmHg (range 1-7), with participants reporting greater relaxation and cognitive focus and less anxiety and sleep disturbance. Multidiscience: Journal of Multidisciplinary Science Google Scholar https://journals.stratapersada.com/index.php/multidiscience/article/view/467
Acupuncture Intervention for Plantar Fasciitis: A Case Study Suyadi, P; Kurniawan, LC; Wardoyo, P; Abdullah, I 2026 Case Study Linking Intervention and Impact Qualitative case study of a 55-year-old man with plantar fasciitis (TCM Cold-Bi syndrome) given six acupuncture sessions with moxibustion at a clinic in Ubud, Bali No Yes Favorable Progressive improvement across sessions with reduced plantar pain, improved functional mobility, and resolution of calf stiffness and sleep disturbance. The patient reported complete pain relief and normal walking by the fifth session, maintained with no recurrence. International Journal of Health and Pharmaceutical (IJHP) Google Scholar https://ijhp.net/index.php/IJHP/article/view/587
Tai Chi and Qigong: Promoting Neurogenesis and Cognitive Health Through BDNF Upregulation in Older Adults: An AI-Assisted Review McGee, RW 2025 Other Linking Intervention and Impact AI-assisted narrative review of Tai Chi and Qigong effects on BDNF, neurogenesis and cognitive health in older adults. The author states the synthesis was prompted by an inquiry to the AI assistant Grok 4, drawing on RCTs, meta-analyses and reviews. Yes No Dementia Mental Health Favorable Review reports Tai Chi and Qigong raise plasma BDNF and improve memory, executive control and depressive symptoms, with BDNF used as an indirect proxy because human neurogenesis cannot be measured directly. Journal of Neurology and Neurological Research Google Scholar https://www.sciencehoodpublishing.org/uploads/articles/1757957037Robert_W__McGee__PDF.pdf
The impact of Tai Chi on osteoporosis and osteopenia in middle-aged and elderly adults: a systematic review and meta-analysis of randomized controlled trial Guo, X; Wang, J; Wang, Y; Sun, Q 2026 Meta Analysis Linking Intervention and Impact Yes Systematic review / meta-analysis of 19 RCTs on Tai Chi for bone mineral density in middle-aged and elderly adults with osteoporosis or osteopenia. Yes Yes Favorable Tai Chi significantly improved bone mineral density, notably at the lumbar spine and hip, in middle-aged and elderly adults with osteoporosis or osteopenia. Osteoporosis International Google Scholar 10.1007/s00198-026-07910-0 https://doi.org/10.1007/s00198-026-07910-0
The effects of Tai Chi Chuan on fall prevention in the elderly: Systematic Review: Tai Chi Chuan and fall prevention in the elderly Rosa, GL; Laranjeira, RM 2026 Systematic Review Linking Intervention and Impact Yes Systematic review of RCTs on adapted Tai Chi Chuan for fall prevention in community-dwelling elderly (>=60 years). Yes Yes Favorable Review concludes adapted Tai Chi Chuan is effective for preventing falls in the elderly by improving balance and reducing fall risk. Manual Therapy, Posturology & Rehabilitation Journal Google Scholar 10.17784/mtprehabjournal.2026.24.1443 https://doi.org/10.17784/mtprehabjournal.2026.24.1443
Effects of Tai Chi and resistance exercise on sleep quality in Japanese community-dwelling older adults with chronic pain Chen, C; Saito, T; Wang, L; Yatsugi, H; Gong, Z; Li, S; Kishimoto, H 2025 RCT Linking Intervention and Impact Yes 12-week controlled trial (71 Japanese community-dwelling older adults with chronic pain): combined Tai Chi + resistance exercise vs control; sleep quality and pain outcomes. Yes Yes Favorable Combined Tai Chi and resistance exercise significantly improved sleep quality and reduced pain intensity and prevalence of sleep difficulty vs control; time-by-group interactions remained significant after adjustment. Geriatric Nursing Google Scholar 10.1016/j.gerinurse.2025.103597 https://doi.org/10.1016/j.gerinurse.2025.103597
Comparison of Tai Chi and Frenkel's Exercises to Improve Balance, Fall Risk and Activities of Daily Living in Patients With Stroke Naveed, F; Bukhari, SP; Basit, H; Ghafoor, A; Tariq, S; Arif, A; Ijaz, HL; Yousaf, A 2025 RCT Linking Intervention and Impact RCT in 36 stroke patients in Sialkot, Pakistan: 8 weeks of modified Tai Chi plus conventional physiotherapy vs Frenkel's exercises plus conventional therapy Yes Neurologic Disorders Favorable Both groups improved significantly on all measures (p<0.05), with the Tai Chi group superior: Barthel Index 58.13 to 85.63 versus 56.88 to 69.38; Berg Balance 35.81 to 45.38 versus 35.50 to 41.94; STRATIFY fall risk 2.62 to 0.94 versus 2.56 to 1.68; between-group differences significant (p<0.05). Insights - Journal of Health and Rehabilitation Google Scholar https://insightsjhr.com/index.php/home/article/view/552
Therapeutic effect of traditional Chinese exercise in stroke patients: An umbrella review of systematic reviews and meta-analyses of clinical trials Luo, B; Zhang, L; Bai, Y; Zhang, F; Liu, Y 2025 Systematic Review Linking Intervention and Impact Yes Umbrella review of 17 systematic reviews and meta-analyses covering 93 RCTs of traditional Chinese exercise (Tai Chi, Baduanjin, Liuzijue, Yijinjing) in stroke patients Yes Neurologic Disorders Favorable Significant pooled benefits for balance (Tai Chi SMD 1.66; Baduanjin SMD 1.70), activities of daily living (SMD 1.22), depression (SMD -0.33) and anxiety (SMD -0.59), but no significant effect on walking ability or sleep quality. GRADE certainty was very low for every outcome. European Journal of Integrative Medicine Google Scholar https://www.sciencedirect.com/science/article/abs/pii/S1876382025000101
Ocena wpływu ćwiczeń tai chi na równowagę i stan funkcjonalny pacjentów z gonartrozą. Darczuk, F 2025 RCT Linking Intervention and Impact No Randomized study of 44 patients with knee osteoarthritis in Chrzanow, Poland: 3 weeks of rehabilitation incorporating Tai Chi vs control Yes Favorable Both groups improved, with significantly greater gains in the Tai Chi group on WOMAC functional status and Berg Balance Scale, plus significant improvements in Timed Up and Go and knee flexion range. Master's thesis, Faculty of Health Sciences (Poland) Google Scholar https://ruj.uj.edu.pl/entities/publication/11b6b2a0-d131-4eaa-b968-8f84a2fa2ccb
Effects of long-term tai chi vs. aerobic exercise on antioxidant activity and cognitive function in individuals with Parkinson’s disease Tsai, CL; Chien, CY; Pan, CY; Tseng, YT; Wang, TC; Lin, TK 2025 RCT Linking Intervention and Impact Yes 12-week RCT (61 Parkinson's patients; aerobic exercise vs Tai Chi vs control) assessing antioxidant activity and cognitive function. Yes Yes Neurologic Disorders Neutral No significant between-group changes in antioxidant markers; both aerobic and Tai Chi exercise may help preserve cognitive function in Parkinson's disease, with aerobic exercise showing greater benefit than Tai Chi. Behavioural Brain Research Google Scholar 10.1016/j.bbr.2024.115274 https://www.sciencedirect.com/science/article/abs/pii/S0166432824004303
Effects of Traditional Chinese Exercise on Mental Health and Physical Function With Chronic Obstructive Pulmonary Disease: A Systematic Review and Meta‐Analysis Ge, B; Liao, X; Lai, F; Luo, J; Wang, Z 2026 Meta Analysis Linking Intervention and Impact Yes Systematic review and meta-analysis of 32 RCTs (n=2,434) on traditional Chinese exercise in COPD pulmonary rehabilitation, searching ten databases to December 2024, appraised with Cochrane RoB 2.0 and prospectively registered (PROSPERO CRD420251007286). Yes Favorable Significant pooled effects for 6-minute walk distance, health-related quality of life (SGRQ, CAT), anxiety, depression, dyspnea and forced vital capacity, with no improvement in FEV1/FVC ratio. Heterogeneity was considerable for most physical and quality-of-life outcomes; adherence was high. Physiotherapy Research International Google Scholar 41804917 https://pubmed.ncbi.nlm.nih.gov/41804917/
Effect of Trunk Training to Improve Balance and Gait Performance Among Stroke Patients: A Review Vidhya Krishna, P; Jeggy, IR 2025 Other Linking Intervention and Impact Narrative review of six studies on trunk training for balance and gait in stroke patients over 18 with more than six months of recovery, covering core stability exercises, sitting Tai Chi, dance therapy, interactive gaming, robotic-assisted therapy, and cycle ergometry. Yes Neurologic Disorders Favorable All reviewed interventions improved trunk control, balance and gait: core stability exercises, sitting Tai Chi and dance therapy via telerehabilitation improved postural stability, robotic-assisted therapy and gaming enhanced motor function, and cycle ergometry promoted balance in acute stroke. World Wide Journal of Multidisciplinary Research and Development Google Scholar https://wwjmrd.com/archive/2025/3/2333/effect-of-trunk-training-to-improve-balance-and-gait-performance-among-stroke-patients-a-review
Beyond pain: Impact of movement-based mindful exercises in fibromyalgia. A systematic review with meta-analysis Fricke-Comellas, H; Heredia-Rizo, AM; Matías-Soto, J; Martínez-Miranda, P; García-Muñoz, C 2026 Meta Analysis Linking Intervention and Impact Yes Meta-analysis of 23 RCTs (1,734 participants) of qigong, yoga and tai chi for fibromyalgia symptoms other than pain Yes Favorable Mindful exercises outperformed active and inactive controls across measures including fatigue (SMD 0.63, 95% CI 0.08-1.17, p=0.04), anxiety and depression, but not sleep quality or overall quality of life. Most included RCTs had a high risk of bias and GRADE certainty was very low. Journal of Bodywork and Movement Therapies Google Scholar 10.1016/j.jbmt.2026.03.019 https://www.sciencedirect.com/science/article/pii/S1360859226000252
Comparison Between Tai Chi and Balance Training on Spatiotemporal Parameters and Dual‐Task Costs During Stair Negotiation in Participants With Knee Osteoarthritis: A Randomized Controlled Trial Zhang, H; Zheng, J; Chai, Y; Huang, X; Wang, X; Hou, M 2025 RCT Linking Intervention and Impact Yes 12-week RCT (69 knee-osteoarthritis participants) comparing Tai Chi vs balance and postural-control training; stair-negotiation spatiotemporal gait parameters and dual-task costs. Yes Yes Favorable Both Tai Chi and balance/postural-control training reduced pain and improved spatiotemporal gait during stair negotiation; Tai Chi showed greater improvement in stair-descent double-stance time, though dual-task-cost gains were limited. Physiotherapy Research International Google Scholar 40503726 10.1002/pri.70075 https://pubmed.ncbi.nlm.nih.gov/40503726/
Comparative efficacy of traditional Chinese exercises for sleep disturbances in older people: A systematic review and Bayesian network meta‐analysis Mei, Z; Cai, C; Lam, C; Wang, T; Luo, S 2025 Meta Analysis Linking Intervention and Impact Yes Systematic review/Bayesian network meta-analysis of RCTs comparing traditional Chinese exercises for sleep disturbances in older people. Yes Yes Favorable Across 17 RCTs (1,730 participants), traditional Chinese exercises significantly improved sleep disturbance in older people (SMD -0.48); Qigong-Baduanjin ranked most effective. European Journal of Integrative Medicine Google Scholar 10.1016/j.eujim.2025.102540 https://www.sciencedirect.com/science/article/abs/pii/S1876382025000897
Effects of 16-week tai chi practice on sit-to-stand performance and lower-limb neuromuscular control strategies in community-dwelling older adults: a randomized controlled trial Mozhu, L; Jiayu, L 2025 RCT Linking Intervention and Impact Yes RCT (60 community-dwelling older adults, 60-75) of a 16-week Yang-style Tai Chi program vs habitual activity; sit-to-stand performance and lower-limb neuromuscular control (COP, EMG). Yes Yes Favorable 16-week Tai Chi significantly improved sit-to-stand performance (reduced Five-Times-Sit-to-Stand and reaction times) with greater lower-limb neuromuscular efficiency vs control. Frontiers in Physiology Google Scholar 10.3389/fphys.2025.1681591 https://www.frontiersin.org/journals/physiology/articles/10.3389/fphys.2025.1681591/full
Effects of exercise interventions on cognitive function in patients with cognitive dysfunction: an umbrella review of meta-analyses Sun, G; Ding, X; Zheng, Z; Ma, H 2025 Systematic Review Linking Intervention and Impact Yes Umbrella review of 55 meta-analyses of RCTs on exercise interventions for cognitive function across dementia, MCI, Alzheimer's, Parkinson's and post-stroke cognitive impairment. Searched Web of Science, PubMed, Embase and Cochrane, graded with GRADE, registered on PROSPERO (CRD42024587635). Yes Yes Dementia Neurologic Disorders Favorable High-quality evidence supported Tai Chi (SMD 0.36) and Chinese mind-body exercises (SMD 0.32) for MMSE/MoCA scores in mild cognitive impairment, and moderate-quality evidence supported Tai Chi (SMD 0.27) in dementia. All findings were Class IV evidence due to small sample sizes. Frontiers in Aging Neuroscience Google Scholar 10.3389/fnagi.2025.1553868 https://www.frontiersin.org/journals/aging-neuroscience/articles/10.3389/fnagi.2025.1553868/full
Pengaruh Tai chi Terhadap Peningkatan Keseimbangan dan Penurunan Resiko Jatuh Pada Lansia (Narrative Review) Zogara, NK; Imron, MA; Fatmawati, V 2025 Other Linking Intervention and Impact Narrative review of 30 international articles (2018-2024) on Tai Chi for improving balance and reducing fall risk in older adults, identified using PICO-structured searches of PubMed, Scopus and Springer Link. Yes No Favorable Review concludes Tai Chi is effective for improving balance and reducing fall risk in older adults across the 30 articles reviewed. Prosiding Seminar Nasional Penelitian dan Pengabdian Kepada Masyarakat LPPM Universitas 'Aisyiyah Yogyakarta Google Scholar https://proceeding.unisayogya.ac.id/index.php/prosemnaslppm/article/view/1171
Effectiveness of Tai Chi balance exercise on fall risk in older adults with cataracts in rural Indonesia Arsyad, AW; Irwan, AM; Syam, Y; Changmai, S; Buckenmeyer, A 2025 Other Linking Intervention and Impact Yes Quasi-experimental pre-post controlled study (56 older adults with cataracts, rural Indonesia) of Tai Chi balance exercise (3x/week, 1 month); fall-risk outcomes. Yes Yes Favorable Fall risk significantly decreased in the Tai Chi group after the 1-month intervention, with no significant change in the control group. Clinical Epidemiology and Global Health Google Scholar 10.1016/j.cegh.2025.102110 https://www.sciencedirect.com/science/article/pii/S221339842500199X
The effect of meditation-based mind-body interventions on older adults with poor sleep quality: a meta-analysis of randomized controlled trials Li, Y; Tang, J; Chen, G 2025 Meta Analysis Linking Intervention and Impact Yes Meta-analysis of 11 RCTs (1,052 participants) on meditation-based mind-body interventions (mindfulness, Tai Chi, yoga, Qigong) for older adults with poor sleep quality. Yes Yes Favorable Meditation-based mind-body interventions significantly improved sleep quality (SMD -0.66), depression, and anxiety in older adults with poor sleep; no significant effect on stress. Behavioral Sleep Medicine Google Scholar 10.1080/15402002.2025.2475911 https://www.tandfonline.com/doi/full/10.1080/15402002.2025.2475911
Traditional Chinese exercises for motor symptoms and mobility in patients with Parkinson's disease: a systematic review and meta-analysis Yuan, F; Wang, H 2025 Meta Analysis Linking Intervention and Impact Yes Systematic review/meta-analysis of 14 RCTs (833 Parkinson's patients) on traditional Chinese exercises (Tai Chi, Qigong) for motor symptoms and mobility. Yes Yes Neurologic Disorders Favorable Traditional Chinese exercises improved motor symptoms (UPDRS-III MD -4.38), functional mobility (TUG), and balance (BBS); Qigong optimal for motor symptoms, Tai Chi for walking/balance. Frontiers in Aging Neuroscience Google Scholar 40904344 https://pmc.ncbi.nlm.nih.gov/articles/PMC12401968/
Effect Of Mind-Body Therapy On Pre-Menopausal Symptoms: A Systematic Review Aswale, ML; Jamadar, K; Adhyapak, S 2025 Systematic Review Linking Intervention and Impact Systematic review of mind-body therapies for menopausal symptoms, covering yoga and meditation programs, tai chi, muscle relaxation, breath-based techniques, relaxation response training and low-frequency sound-wave therapy Yes Favorable Eight of nine studies of yoga, tai chi and meditation-based programs reported improvement in overall menopausal and vasomotor symptoms; six of seven yoga trials improved mood and sleep; four studies reported reduced musculoskeletal pain. Cuestiones de Fisioterapia Google Scholar https://www.researchgate.net/publication/389610305_Effect_Of_Mind-Body_Therapy_On_Pre-Menopausal_Symptoms_A_Systematic_Review
Yoga for Symptom Management in Oncology: A Review of the Evidence Base and Future Directions for Research Danhauer, SC; Addington, EL; Cohen, L; Sohl, SJ; Van Puymbroeck, M; Albinati, NK; Culos-Reed, SN 2019 Other Linking Intervention and Impact Yes Review of 29 randomized controlled trials of yoga across the cancer continuum (13 during treatment, 12 post-treatment, 4 mixed samples), covering quality of life, fatigue, stress, sleep, cognition, and biological markers. Yes Cancer Favorable Yoga improved overall quality of life during and after cancer treatment, most consistently for fatigue, and also reduced stress/distress and improved post-treatment sleep, cognition, and stress and inflammation biomarkers. Findings were limited or mixed for anxiety, depression, pain, and lymphedema; most trials enrolled breast cancer patients. Cancer Google Scholar 10.1002/cncr.31979 https://doi.org/10.1002/cncr.31979
Efficacy of Yoga in Treating Positive and Negative Symptoms of Schizophrenia and Enhancing Social Functioning: A Systematic Review and Meta-Analysis of Randomized Controlled Trials Geremias, ML; Victoria de Vasconcelos, A; Balduino de Souza, AL; Borja De Oliveira, I; Santos Raposo Andrade, I; Soares Campos, VM; Soler Lopes, D 2025 Meta Analysis Linking Intervention and Impact Yes PRISMA systematic review and meta-analysis of 16 RCTs (862 participants; yoga n=393) comparing yoga with treatment-as-usual, other physical activity, or waitlist in schizophrenia, assessing PANSS symptom severity and social functioning. Yes Mental Health Favorable Overall symptom severity fell relative to control (PANSS MD -6.61, p=0.05, I2=82%). Positive symptoms improved versus waitlist (SMD -0.87) and treatment-as-usual (SMD -0.65) but not versus physical activity, with no effect on negative symptoms or social functioning. European Psychiatry Google Scholar 10.1192/j.eurpsy.2025.343 https://doi.org/10.1192/j.eurpsy.2025.343
Comparative efficacy of various mind-body exercise types on cardiometabolic health in patients with type 2 diabetes: a network meta-analysis of randomized controlled trials Li, X; Gao, M; Hua, J 2025 Meta Analysis Linking Intervention and Impact Yes Network meta-analysis of RCTs comparing mind-body exercise types on cardiometabolic risk factors in patients with type 2 diabetes. Yes Yes Diabetes Favorable Mind-body exercises produced unique and superior effects on cardiometabolic risk factors (glucose metabolism, body composition, cardiovascular measures, lipids) versus conventional exercise in type 2 diabetes. BMC Cardiovascular Disorders Google Scholar 10.1186/s12872-025-04745-1 https://doi.org/10.1186/s12872-025-04745-1
The Effect Of Prenatal Yoga On The Mental Health Of Third Trimester Pregnant Women Dianna, D; Sulistiawati, R; Kaamilah, N 2025 Other Linking Intervention and Impact Quasi-experimental pre-post study of prenatal yoga in 20 third-trimester pregnant women attending antenatal care at Tekarang Public Health Center, Sambas, Indonesia (10 intervention, 10 control; purposive sampling), with mental health measured by the Hospital Anxiety and Depression Scale. Yes Mental Health Favorable A significant pre-post difference in HADS scores was reported (p = 0.000). Jurnal Kebidanan Malahayati Google Scholar https://ejurnalmalahayati.ac.id/index.php/kebidanan/article/view/23147
Yoga Therapy as a Complementary Approach in the Management of Knee Osteoarthritis Rawat, K; Sahu, V; Pedhekar, SR 2025 Other Linking Intervention and Impact Narrative review of the literature on yoga for knee osteoarthritis, focusing on pain relief, joint function, muscle strength, and psychological well-being. Yes Favorable Review concludes yoga can be an effective adjunct to standard care for knee osteoarthritis, with physical and psychosocial benefits and minimal adverse effects, while noting variability in study designs and yoga protocols and calling for rigorous RCTs. International Journal on Science and Technology Google Scholar https://www.ijsat.org/papers/2025/3/7928.pdf
Effect of Integrated Yoga and Naturopathy Treatments on Blood Pressure Changes Among Patients with Hypertension: A Retrospective Data Analysis. Deepa, Y; Kumar, KM; Gowtham, S; Manavalan, N; Christa, SE 2025 Other Linking Intervention and Impact Yes Retrospective cohort of 281 hypertensive inpatients who completed a standardized 15-day integrated yoga and naturopathy program, comparing those on antihypertensive medication (n=156) with those without (n=125) Yes Cardiovascular Disorders Favorable Both groups significantly reduced SBP, DBP, heart rate, pulse pressure, and MAP (p<0.05), with a greater fall in the non-medicated group (SBP 142.1 to 129.8) than the medicated group (SBP 126.2 to 118.7), intergroup p<0.01. Advances in Mind-Body Medicine Google Scholar 40489372 https://pubmed.ncbi.nlm.nih.gov/40489372/
Efficacy of Structured Yoga Intervention on Glycemic Control and Body Mass Index in Prediabetic Obese Adults: A Six-Month Prospective Cohort Study Priya, BM; Velayutham, V; Ezhilarasi, S; Udayakumar, R; Gunasekar, A 2026 Prosp Cohort Study Linking Intervention and Impact Single-arm prospective cohort of 100 adults aged 20-50 with prediabetes receiving structured yoga (90-minute sessions, three times weekly) for six months No Yes Diabetes Favorable Mean fasting blood glucose fell from 117.1 to 86.4 mg/dL and BMI from 26.3 to 22.7 kg/m2 (both p<0.001), with 78% of participants reaching normoglycemia and 89% a normal BMI. Efficacy was comparable between males and females. Acta Medica International Google Scholar https://www.parsvnath.in/journals/acta-medica-international/articles/efficacy-of-structured-yoga-intervention-on-glycemic-control-and-body-mass-index-in-prediabetic-obese-adults-a-six-month-prospective-cohort-study
Effects of yoga interventions on cardiac autonomic function in patients with diabetes: a randomized controlled study. Mahalingam, M; Sehgal, N; Chugh, S; Savale, TK; Yadav, R; Sebastian, B; Astuti, Y 2025 RCT Linking Intervention and Impact Yes RCT in 90 adults with type 2 diabetes randomized to a 12-week yoga program (60-minute sessions, three times weekly; n=45) or usual care (n=45), with short-term heart rate variability assessed in time and frequency domains at baseline and post-intervention. Yes Diabetes Favorable Yoga group improved on time-domain HRV (mean RR, mean HR, SDNN, RMSSD, pNN50; p<0.05) and frequency-domain measures (HF power up, p=0.03; LF power down, p=0.02; LF/HF ratio down, p=0.04), indicating greater parasympathetic activity, while controls declined on SDNN and pNN50. Fizjoterapia Polska Google Scholar https://fizjoterapiapolska.pl/en/article/wplyw-interwencji-jogi-na-autonomiczna-funkcje-serca-u-pacjentow-z-cukrzyca-randomizowane-badanie-kontrolowane/
Effect of a Yoga and Naturopathy-Based Lifestyle Intervention with 9-Month Follow-Up on Lipid Profile in Patients with Hypertension: A Two-Arm Parallel Group Randomized Controlled Trial Shetty, P; Janardhana, SK; Aruchunan, M; Subbanna, NN; Jayasingh, JK; Prakash, AV 2025 RCT Linking Intervention and Impact Yes Two-arm parallel randomized controlled trial in 262 hypertensive patients: 10 days of yoga and naturopathy treatments (n=131) versus no intervention (n=131), with lipid profile measured at baseline, day 10, and 9-month follow-up. Yes Cardiovascular Disorders Favorable Study group showed significant changes versus control in total cholesterol, triglycerides, HDL, LDL, VLDL, Apo-A, Apo-B and Lp-A (p<0.001) at 10 days, with Apo-A, Apo-B and Lp-A still differing at 9 months. Complementary Medicine Research Google Scholar 39701056 10.1159/000543024 https://doi.org/10.1159/000543024
Effectiveness of Yoga and Naturopathy in Managing Hashimoto’s Thyroiditis: A Case report with Surgical Decision-Making Implications Venkatesan, C; Kumar, M 2026 Case Study Linking Intervention and Impact Case report: 51-year-old woman with Hashimoto's thyroiditis completed a seven-day inpatient integrative program (yoga neck exercises, hydrotherapy, anti-inflammatory diet), continued at home for three months Yes Autoimmune Disease Favorable Reported substantial reduction in neck swelling, resolution of dysphagia and improved voice quality, with thyroid hormone levels remaining stable and modest decreases in anti-TPO and anti-TG titres. No adverse effects were observed and the patient was able to defer surgery. Swasthavritta: Journal on Diet, Hygiene, Yoga & Naturopathy Google Scholar https://admin.mantechpublications.com/index.php/SJoDHYN/article/download/2534/1050
Emerging Lifestyle Intervention and Alternative Therapies for Gut Modulation in Women's Health: A Focus on Menstrual, Reproductive and Hormonal Health. Setia, M; Awasthi, M 2026 Other Linking Intervention and Impact Yes Narrative review of diets, dietary bioactive compounds and alternative therapies (yoga, meditation, time-restricted eating) for gut microbiota and hormonal health in PCOS, endometriosis and menopause Yes Favorable Review reports that fibre- and antioxidant-rich diets such as the Mediterranean diet promote beneficial bacteria and hormonal balance, and that yoga, meditation and time-restricted eating show promise in restoring microbial diversity and improving clinical outcomes in gut-mediated disorders. Journal of Clinical and Diagnostic Research Google Scholar https://jcdr.net/article_fulltext.asp?issn=0973-709x&year=2026&month=March&volume=20&issue=3&page=03&id=22986
The Role of Kundalini Yoga in Alleviating Early Pregnancy Dis-Comforts: A Pre-Post Test Experimental Study Khusmitha, QN; Farokah, A; Putri, HFW 2025 RCT Linking Intervention and Impact Randomized pre-post controlled trial in 50 first-trimester pregnant women at Polindes Mancon, Nganjuk, Indonesia: Kundalini Yoga versus standard prenatal care over four weeks, with anxiety and nausea and vomiting in pregnancy measured by validated questionnaires. No Yes Mental Health Favorable Treatment group showed significant reductions versus control in anxiety (p=0.039) and nausea and vomiting (p=0.000); within-group anxiety fell in the treatment arm (p=0.002) but not the control arm (p=0.102). Nausea and vomiting improved in both arms (treatment p=0.000, control p=0.013). Jurnal Kedokteran Diponegoro (Diponegoro Medical Journal) Google Scholar https://ejournal3.undip.ac.id/index.php/medico/article/view/49685
The effects of Tai Chi on pain and other health indicators in people with osteoarthritis: An updated systematic review and dose-response meta-analysis Zhao, A; Brown, WJ; Coombes, JS; Liu, X 2025 Meta Analysis Linking Intervention and Impact Yes Updated systematic review / dose-response meta-analysis of RCTs on Tai Chi for pain and other health indicators in adults with osteoarthritis (28 studies, 1,676 participants). Yes Yes Favorable Tai Chi significantly improved pain (Cohen's d -0.64), mobility, self-reported physical function, and stiffness vs non-exercise comparators; effects were similar to other forms of exercise. Osteoarthritis and Cartilage Google Scholar 10.1016/j.joca.2025.05.013 https://www.sciencedirect.com/science/article/abs/pii/S1063458425010350
The effect of Tai Chi on plasma homocysteine in 1176 adults: a propensity score matching-based study Gu, Y; Bai, J; Li, Y; Han, L; Wang, D 2025 Other Linking Intervention and Impact Yes Propensity-score-matched cross-sectional study comparing plasma homocysteine and hyperhomocysteinemia risk between long-term Tai Chi practitioners (n=397) and non-exercising controls (n=779). Yes Yes Cardiovascular Disorders Favorable Long-term Tai Chi practice was associated with significantly lower plasma homocysteine levels (p=0.008), a cardiovascular risk marker; causality cannot be established (cross-sectional). BMC Cardiovasc Disord Google Scholar 39875831 10.1186/s12872-025-04519-9 https://doi.org/10.1186/s12872-025-04519-9
The Effect of Adherence to a Tai Chi Intervention on Quality of Life of Older People Living With Dementia Bibi, I; Polman, R; Nyman, SR 2025 RCT Linking Intervention and Impact Yes Analysis within the TACIT RCT (41 community-dwelling people with dementia): adherence to a 20-week Tai Chi exercise program (added to usual care) and its effect on quality of life. Yes No Dementia Favorable Adherence to Tai Chi was high; quality of life was significantly higher in highly adherent participants. Participants' and carers' health conditions were the main barriers to adherence. J Aging Phys Act Google Scholar 39753119 10.1123/japa.2024-0017 https://doi.org/10.1123/japa.2024-0017
The Impact of Tai Chi on Balance, Falls and Cognitive and Motor Health in Older Adults. Wayne, P 2025 Other Linking Intervention and Impact Yes Conference presentation synthesizing evidence on Tai Chi's effects on cognition, gait, balance, and fall prevention in older adults, including dual-task cognitive-motor outcomes. Yes Yes Favorable Presentation highlights that Tai Chi, as a mind-body exercise, improves balance, gait, fall prevention, and cognitive-motor function in older adults (conference abstract summarizing RCT and cross-sectional evidence). Innovation in Aging Google Scholar 10.1093/geroni/igaf122.1831 https://doi.org/10.1093/geroni/igaf122.1831
Evaluate the effect of Tai Chi Chuan in lung cancer survivors by using the biomarkers Loo, WTY; Hunt, JJ; Cheung, MNB; Loo, PC 2025 Other Linking Intervention and Impact Yes Review of Tai Chi Chuan as rehabilitation for non-small cell lung cancer survivors, examining biomarkers of inflammation, oxidative stress and immune function alongside health-related quality of life. Yes Cancer Favorable Review reports Tai Chi Chuan reduces pro-inflammatory cytokines (IL-6, TNF-alpha) and raises antioxidant enzyme activity, while improving physical functioning, cancer-related fatigue, psychological well-being, and social connection among survivors. The authors call for rigorous RCTs. World Journal of Biology Pharmacy and Health Sciences Google Scholar 10.30574/wjbphs.2025.23.1.0653 https://doi.org/10.30574/wjbphs.2025.23.1.0653
The effects of time-restricted eating combined with Tai Chi on glycolipid metabolism and endothelial function in postmenopausal women Wang, XY; Chen, J; Li, H 2025 RCT Linking Intervention and Impact Yes Three-arm RCT in 142 postmenopausal women aged 50-60: time-restricted eating plus 24-form Tai Chi vs time-restricted eating alone vs conventional lifestyle control over 8 weeks No Yes Favorable Significant group-by-time interactions for total cholesterol (p=0.001) and LDL-C (p=0.003), with the combined group showing the largest reductions versus time-restricted eating alone and versus control. Flow-mediated dilation also improved, but only the combined group exceeded control (p=0.003). Journal of the International Society of Sports Nutrition Google Scholar 10.1080/15502783.2025.2581148 https://doi.org/10.1080/15502783.2025.2581148
Yoga And Its Impact On Physical And Mental Health: A Review Article GOUD, KAG 2026 Other Linking Intervention and Impact Single-author narrative review of the physiological and psychological benefits of yoga (postures, breathing, meditation) and its role in managing lifestyle disorders. Yes Favorable Review asserts that regular yoga practice improves cardiovascular function, reduces stress, enhances mental clarity, and aids disease prevention, while noting that standardized research is still needed to establish clinical efficacy. National Journal of Medical Research and Yoga Sciences Google Scholar https://njmrys.com/index.php/files/article/view/45
Effectiveness of Himalayan Traditional Yoga Practices on Psychological and Pain-Related Parameters in Patients With Migraine Singh, A; Sharma, A 2025 Other Linking Intervention and Impact Four-week yoga therapy intervention in patients with migraine. Primary outcomes were headache frequency (diary), migraine severity (0-10 numerical rating scale), and pain via the McGill Pain Questionnaire; secondary outcomes were HADS anxiety and depression and symptomatic medication use. Yes Neurologic Disorders Favorable Significant improvements reported on all outcomes after four weeks: headache intensity, headache frequency, McGill pain rating index, HADS anxiety and depression scores, and symptomatic medication use (all P < .001). South Eastern European Journal of Public Health Google Scholar https://www.seejph.com/index.php/seejph/article/download/4511/2976/6867
The Efficacy of Yoga therapy on Risk Reduction in High-risk Pregnancy. A Narrative Review Jogdand, RP; Maharana, S; Patil, S; Nagarathna, R; Mohanty, S 2025 Other Linking Intervention and Impact Narrative review of yoga intervention in high-risk pregnancy, searching PubMed, Web of Science, and Embase through February 2023; 138 articles retrieved and 17 included. Yes Favorable Review concludes yoga reduces pregnancy-induced hypertension, pre-eclampsia, intrauterine growth restriction, and preterm birth, and improves quality of life, mental and physical health, APGAR scores, and fetal birth weight. Journal of Complementary and Alternative Medical Research Google Scholar https://journaljocamr.com/index.php/JOCAMR/article/view/700
Yoga as a Cost-Effective Adjunct Therapy for Dry Eye: Clinical outcomes from a Twelve-Week Randomized Controlled Trial Abraham, L; Bhat, R; George, S 2026 RCT Linking Intervention and Impact Yes Open-label parallel-group RCT in 49 adults aged 20-40 with mild-to-moderate dry eye: online Jyothi Trataka practice 25 minutes, 3 days/week for 12 weeks (24 completers) versus no intervention (22 completers), assessed by OSDI, tear breakup time, Schirmer's score, and tear meniscus height. No Yes Favorable Yoga group improved significantly versus control on OSDI symptom score (p < 0.01) and tear breakup time (p < 0.01), with no significant change in Schirmer's score or tear meniscus height. Frontiers in Medicine Google Scholar 10.3389/fmed.2026.1795593 https://doi.org/10.3389/fmed.2026.1795593
Impact of a residential yoga and naturopathy intervention on blood glucose and diabetes related risk factors in patients with type 2 diabetes mellitus: A retrospective study Mooventhan, A; Nivethitha, L; Subramanian, KK; Vijay, A; Manavalan, N 2025 Other Linking Intervention and Impact Yes Retrospective chart review of 407 inpatients with type 2 diabetes who completed a residential integrated yoga and naturopathy program (2019-2022) Yes Diabetes Favorable Significant pre-post reductions in fasting and post-prandial blood glucose, weight, BMI, waist and hip measures, perceived stress, blood pressure, pulse rate, and derived cardiac indices. An erratum was later issued regarding missing data statements. Brain Behavior and Immunity Integrative Google Scholar 10.1016/j.bbii.2024.100101 https://www.sciencedirect.com/science/article/pii/S2949834124000576
Yoga for the Management of Diabetes Datti, RS 2025 Other Linking Intervention and Impact No Single-arm pre-post study reported as a book chapter: 35 participants with type 2 diabetes (mean age 50.3) followed a stepped-care yoga protocol for 40 days, with fasting plasma glucose, total cholesterol, BMI, well-being, and self-reported sleep quality measured before and after. Yes Diabetes Favorable Reported reductions in BMI, fasting plasma glucose, and total cholesterol, with less depression and anxiety, greater well-being and energy, and improved sleep initiation and fewer sleep disturbances; the author states psychological effects were more pronounced than clinical ones. Yoga and Meditation (book chapter, Apple Academic Press) Google Scholar 10.1201/9781003568308-13 https://www.taylorfrancis.com/chapters/edit/10.1201/9781003568308-13/yoga-management-diabetes-ravi-shanker-datti
Chronic Low Back Pain in Veterans and the Role of Yoga: An Overview of Randomized Controlled Trials Thanneeru, SK; Chanchlani, R; Sharma, PK; Agarwal, S; Srinivas, N; Sukumar, M; Agrawal, A 2022 Systematic Review Linking Intervention and Impact Yes Systematic review of yoga for chronic low back pain in veterans: PubMed, Scopus, ScienceDirect, and Cochrane searched, 68 articles identified and 6 included covering 608 patients, appraised with PRISMA and the JBI tool and synthesized qualitatively. Yes Favorable Pain improvement was statistically significant across all six included studies, with similar results for disability and psychological indexes. Synthesis was qualitative with no pooled estimate; authors call for more RCT evidence. Manipal Journal of Medical Sciences Google Scholar https://impressions.manipal.edu/mjms/vol7/iss2/3/
A Case Study of Chronic Fungal Urinary Tract Infection: Resolution Through Yoga Prana Vidya (YPV) Healing Nayak, L; Nanduri, VS 2025 Case Study Linking Intervention and Impact Case report: 37-year-old woman with 17-year recurrent chronic fungal UTI treated with Yoga Prana Vidya energy healing, breathing exercises, psychotherapy and a salt-free fruit-based diet Yes Favorable Patient reported significant symptom relief within two days and complete resolution within one month; a urine test at two months showed no yeast cells and no recurrence over two months of follow-up. International Journal of Medical Science and Dental Health Google Scholar https://www.ijmsdh.org/index.php/ijmsdh/article/view/525
Study of Effects of Yoga on Patients with Bronchial Asthma: A Randomized Controlled Study Rasheeka, VP; Meshram, PL; Hegde, RR; Pujari, V 2025 RCT Linking Intervention and Impact Yes RCT in 100 patients with mild-to-moderate bronchial asthma at a tertiary care hospital: 8 weeks of supervised yoga plus standard medical therapy (n=50) versus standard therapy alone (n=50), with spirometry, 6-minute walk distance, and Asthma Control Test measured at baseline, 4 weeks, and 8 weeks. Yes Favorable Yoga group improved more than control on FEV1 (+3.5% vs +1.1%), PEFR (+30.7 vs +12 L/min), FEF25-75 (+47.1% vs +16.2%), Asthma Control Test (+3 vs +1 points), and 6-minute walk distance (+30 m vs +11 m). Journal of PACS Google Scholar https://www.researchgate.net/publication/394498806
Association Between Regular Yoga Practice and Reduced Incidence of Acute Coronary Syndrome in Hypertensive Adults Nnadi, E; Masara, M; Offor, R; Yosry, N; Nigussie, B; Atere, M; Graham-Hill, S 2025 Other Linking Intervention and Impact Yes Retrospective propensity-matched cohort in the TriNetX network: 1,269,231 hypertensive adults with yoga-related encounters vs an equal number with none; incident acute coronary syndrome within 3 years Yes Cardiovascular Disorders Favorable ACS occurred in 0.6% of the yoga group vs 2.0% of controls (HR 0.41), with lower stroke/TIA (HR 0.54) and cardiac arrest (HR 0.88), all p<0.0001. All-cause mortality was higher in the yoga group (12.0% vs 6.9%, HR 2.29), which authors attribute to residual confounding or reverse causation. Circulation Google Scholar 10.1161/circ.152.suppl_3.4373688 https://www.ahajournals.org/doi/abs/10.1161/circ.152.suppl_3.4373688
Yoga as a Lifestyle Modification Strategy for Early Prevention of Obesity Related Risks in Healthy Young Men Sharma, P; Rawat, A; Jha, S; Surywanshi, C; Ahirwar, B; Singh, MV 2025 Other Linking Intervention and Impact Single-arm pre-post study in 50 healthy men aged 18-35 recruited from one gym in Uttar Pradesh, India: progressive five-week yoga program (six days/week, 33-85 minutes), with anthropometry and body composition by bioelectrical impedance analysis, analyzed by paired t-tests. No Yes Favorable Significant reductions in body weight (63.48 to 57.06 kg), BMI (23.32 to 20.96), body fat (18.45% to 15.62%), and all regional fat indices (all p<0.0001). Lean mass, skeletal muscle mass, and basal metabolic rate (1526 to 1462 kcal/day) also fell significantly. Journal of Carcinogenesis Google Scholar https://www.researchgate.net/publication/395793547_Yoga_as_a_Lifestyle_Modification_Strategy_for_Early_Prevention_of_Obesity_Related_Risks_in_Healthy_Young_Men
Is Yoga More Beneficial than Exercise-Based Interventions for Patients with Chronic Low Back Pain? A Systematic Review and Meta-Analysis Zhang, L; Li, T; Wen, Q 2026 Meta Analysis Linking Intervention and Impact Yes Systematic review/meta-analysis of RCTs comparing yoga vs active exercise interventions on pain, disability, and emotional well-being in adults with chronic low back pain. Yes Yes Favorable Yoga improved pain, physical function/disability, and emotional well-being in chronic low back pain, with effects comparable to other active exercise-based programs. Frontiers in Medicine Google Scholar 10.3389/fmed.2026.1792208 https://doi.org/10.3389/fmed.2026.1792208
Integrative Varma Chikitsa and Yoga Therapy in Musculoskeletal and Neuropathic Disorders: A Case Series from a Traditional Ayurvedic Practice Saravanabhava, M; Rajasekhar, KV; Sudhan, P; Subbulakshmi, V; Dwarakanath, D 2026 Case Study Linking Intervention and Impact Case series of five patients aged 35-54 with musculoskeletal conditions treated over 7-21 days with Varma Chikitsa vital-point stimulation, Panchakarma, Ayurvedic medication and yoga therapy Yes Favorable All five patients reported marked improvement, with pain reduction ranging from moderate to about 90%, restored shoulder range of motion, resolution of carpal tunnel symptoms, 7 kg weight loss in one obese patient, and remission of recurrent sinusitis; no adverse events. International Journal of Yoga, Sports, and Health Sciences Google Scholar https://ijyshs.melangepublications.com/index.php/ijyshs/article/view/32/
Effectiveness of a Yoga-Based Intervention in Alleviating Depressive Symptoms Among Older Adults: A Case Study Uliyah, M; Susanty, A 2025 Case Study Linking Intervention and Impact Case study of two older adults with moderate depression at a nursing home in Surabaya, Indonesia: four-day yoga program with daily 30-40 minute sessions, assessed by Geriatric Depression Scale before and after. Yes No Mental Health Favorable Both participants moved from moderate depression to a non-depressed GDS score after four days. The authors attribute the improvement to enhanced physical and psychological functioning and potential reductions in cortisol. Jurnal Keperawatan Muhammadiyah Google Scholar https://journal.um-surabaya.ac.id/JKM/article/view/27440
Impact of short-term integrated yoga therapy intervention on systemic inflammatory markers and quality of life in rheumatoid arthritis patients: A randomized controlled trial Shetty, GB; Shetty, P; Shetty, B; Nanjeshgowda, HL 2025 RCT Linking Intervention and Impact Yes RCT in 100 rheumatoid arthritis patients aged 18-60: 12 weeks of structured yoga therapy alongside usual DMARD treatment (n=50) versus control (n=50), with inflammatory markers, DAS-28 disease activity, VAS pain, and SF-36 quality of life assessed. No Yes Autoimmune Disease Favorable Versus control, the yoga group significantly reduced IL-6 (P<.001), CRP (P<.01), rheumatoid factor (P=.02) and ESR (P=.05), and improved DAS-28 (P<.001), patient global assessment (P<.001), VAS pain (P<.01) and SF-36 quality of life (P=.05). Integrative Medicine: A Clinician's Journal Google Scholar 39896828 https://pubmed.ncbi.nlm.nih.gov/39896828/
Yoga for Eye Disorders-A Systematic Review. Abraham, L; George, S; Bhat, R 2026 Systematic Review Linking Intervention and Impact Yes Systematic review of yoga-based interventions for glaucoma, refractive errors, dry eye disease, and visual strain: MEDLINE/PubMed searched January 2000 to April 2025, 14 experimental studies included, risk of bias assessed with Cochrane RoB 2 and ROBINS-I, PRISMA followed. Yes Favorable Strong evidence supports meditation and pranayama as adjuncts for reducing intraocular pressure in glaucoma, but evidence for myopia and dry eye disease was limited and inconclusive. Included studies commonly had small samples, short intervention durations, and subjective outcome measures. Advances in Mind-Body Medicine Google Scholar 41217898 https://pubmed.ncbi.nlm.nih.gov/41217898/
Yoga Therapy in Oncology. Features of Working with Geriatric Patient Miranovich, VV 2025 Other Linking Intervention and Impact Narrative review of yoga therapy as a modality of integrative oncology and onco-gerontology, summarising research across active treatment, terminal stage, remission, and recovery, and describing the Holistic Approach to Yoga Therapy model for cancer and onco-geriatric patients. Yes Yes Cancer Favorable Author reports a growing evidence base supporting yoga therapy in oncology for improving quality of life and reducing side effects of conventional treatment, while noting that the underlying biochemical pathways remain unclear and research is still limited. Practical Oncology (Отечественная Школа Онкологов) Google Scholar 10.31917/2603265 https://practical-oncology.ru/en/journal/mesto-yoga-terapii-v-onkologii-osobennosti-raboty-s-geriatricheskimi-patsientami
A case study of woman patient with Ulcerative colitis in rectum treated successfully using Yoga Prana Vidya (YPV) Healing protocols D’Souza, RS; Nayak, L; Nanduri, VS 2025 Case Study Linking Intervention and Impact A 33-year-old woman with ulcerative colitis localized to the rectum received Yoga Prana Vidya energy-healing sessions from two healers over three months (with gaps), including energy cleansing and energising, pranic breathing, forgiveness-based psychological healing, and dietary regulation. No Yes Autoimmune Disease Favorable Reported resolution of abdominal discomfort and rectal bleeding, normalized bowel movements, and improved energy, with no surgery required and no adverse effects. International Journal of Medical and Health Research Google Scholar https://www.yogapranavidya.com/publications/a-case-study-of-woman-patient-with-ulcerative-colitis-in-rectum-treated-successfully-using-yoga-prana-vidya-ypv-healing-protocols-2/
Musculoskeletal Effects of Yoga in Yoga Science Bala, A 2024 Other Linking Intervention and Impact Single-author narrative review of mechanisms by which yoga affects musculoskeletal health - flexibility, strength, pain reduction, posture correction, and injury prevention - drawing on scientific evidence, clinical studies, and traditional yogic theory. Yes Favorable Review asserts yoga has a beneficial effect on musculoskeletal health and argues for integrating yoga into rehabilitation and preventive care for musculoskeletal disorders. Journal of Advances in Developmental Research Google Scholar https://www.ijaidr.com/research-paper.php?id=1498
Effect of Yoga and Naturopathy on an Obese Male Patient: A Case Report Nair, J; Joicy, SM; Logeshwaran, S 2025 Case Study Linking Intervention and Impact A middle-aged obese man presenting with weight gain, raised blood pressure, and altered serum lipid profile received combined yoga and naturopathy treatment including massage therapy, fasting, diet therapy, and yoga therapy. Treatment duration is not stated. Yes Cardiovascular Disorders Favorable Weight fell from 110 to 102.5 kg and BMI from 39 to 36.3; blood pressure fell from 160/120 to 118/84 and was maintained without medication; LDL fell from 138 to 116 mg/dl and total cholesterol from 203 to 186 mg/dl, with improvement in breathing difficulty, body heaviness, and walking. Indian Journal of Integrative Medicine Google Scholar https://mansapublishers.com/ijim/article/view/7639
The Impact of Yoga as an Adjunct to Standard Care on Glycemic Control, Insulin Resistance, Oxidative Stress, and Quality of Life in Individuals with or at Risk of Type 2 Diabetes Mellitus: A Systematic Review and Meta-Analysis Javed, D; Chandra, MB; Malhotra, V; Mudda, S; R, P; Karrothu, VV; Adusumilli, MB; Chenchula, S 2025 Meta Analysis Linking Intervention and Impact Yes Systematic review/meta-analysis of RCTs on yoga (asanas, pranayama, meditation) as an adjunct to standard care for glycemic control, insulin resistance, oxidative stress, and quality of life in type 2 diabetes. Yes Yes Diabetes Favorable Yoga as adjunct to standard care improved glycemic control and insulin resistance, reduced oxidative stress, and enhanced psychological well-being in adults with or at risk of type 2 diabetes. Current Diabetes Reviews Google Scholar 40993952 10.2174/0115733998383494250827215758 https://pubmed.ncbi.nlm.nih.gov/40993952/
Effect of a Year-long Yoga-Based Lifestyle Intervention on Glycemic Control, Body Weight, Psychological Health, and Imaging Biomarkers in Adults with Type 2 Diabetes: A Randomized Controlled Trial Bhargav, H; Bista, S; Jasti, N; Chikkanna, U; Kumar, S; Varmbally, S; Srikanta, S; Nagarathna, R; Padmavati, R; Kusneniwar, G 2025 RCT Linking Intervention and Impact Yes Two-arm assessor-blinded RCT (160 adults with type 2 diabetes, mean age ~53): year-long yoga-based lifestyle vs physical exercise + health education; glycemic control, weight, psychological health, imaging biomarkers. No Yes Diabetes Favorable Authors conclude that the yoga-based lifestyle intervention showed superior efficacy over the standard physical exercise and health education program, with improvements in glycemic control, psychological health, and novel imaging biomarkers, and that further mechanistic studies are warranted. Advances in Mind-Body Medicine Google Scholar 41118624 https://pubmed.ncbi.nlm.nih.gov/41118624/
Impact of Yoga Practices on Digestive Disorders: A Comprehensive Review of Therapeutic Mechanisms and Clinical Evidence Godara, R 2025 Other Linking Intervention and Impact Narrative review of yoga (breathing, meditation, asanas) as a complementary approach to irritable bowel syndrome, GERD, inflammatory bowel disease and functional dyspepsia Yes Favorable Yoga practices reduced symptom severity, improved quality of life and enhanced digestive function, with proposed mechanisms including stress reduction, autonomic regulation and gut-brain axis modulation. Sanatanodaya Google Scholar https://sanatanodaya.com/index.php/dj/article/view/70
Effect of a 25-Day Structured Yoga Therapy Program on a Small Paraumbilical Hernia: A Single-Case Clinical Report Naragatti, S 2026 Case Study Linking Intervention and Impact A supervised 25-day yoga therapy program (1 hour/day) in a 35-year-old female with a small, reducible paraumbilical hernia; assessed on hernia defect size, abdominal circumference, and body weight. Yes Favorable Over 25 days, hernia defect size fell from 10 mm to 5 mm, abdominal circumference from 108 cm to 97 cm, and weight from 63 kg to 58 kg. The author notes controlled trials are needed to substantiate the outcomes. International Journal of Science and Research (IJSR) Google Scholar https://www.ijsr.net/getabstract.php?paperid=SR26404121641
The impact of engaging in yoga for PTSD following Military Sexual Trauma: A Systematic Review. An Interpretative Phenomenological Analysis of women's experience of engaging in yoga following a sexual assault. Jackson, N 2025 Systematic Review Linking Intervention and Impact No Doctoral thesis: systematic review of five studies of yoga for military sexual trauma-related PTSD, plus phenomenological analysis of interviews with three women Yes Mental Health Favorable Yoga may reduce PTSD symptoms in women veterans with military sexual trauma-related PTSD, with clinically significant symptom improvement and high treatment retention across studies of variable quality. Evidence on other wellbeing outcomes was limited. University of Exeter (doctoral thesis) Google Scholar https://ore.exeter.ac.uk/articles/thesis/The_impact_of_engaging_in_yoga_for_PTSD_following_Military_Sexual_Trauma_A_Systematic_Review_An_Interpretative_Phenomenological_Analysis_of_women_s_experience_of_engaging_in_yoga_following_a_sexual_assault_/30454856
Complementary therapies for chronic knee pain: a placebo-controlled RCT of Reiki and mindfulness Hanley, AW; Nakamura, Y; Edwards, RR; Lingard, A; Childs, K; Faulkner, J; Schnitt, R; Claire, SVS; Bridge, E; Garland, EL 2025 RCT Linking Intervention and Impact Yes 4-arm placebo-controlled RCT (164 adults with knee OA): Reiki vs sham Reiki vs mindfulness meditation vs waitlist; four weekly 30-min sessions; WOMAC symptom severity. Yes Yes Favorable Both Reiki (p=.02) and mindfulness significantly improved knee-OA symptom severity (WOMAC) at 1- and 2-month follow-up compared with control. Complementary Therapies in Medicine Google Scholar 10.1016/j.ctim.2025.103278 https://doi.org/10.1016/j.ctim.2025.103278
Yoga and Telomere Length: Exploring Anti-Aging Effects at Cellular Level Kaur, MM; Ahluwalia, PS 2025 Other Linking Intervention and Impact Yes Narrative review of yoga's neurobiological and anti-aging mechanisms, focused on telomere length and cellular aging. Yes Yes Favorable Review concludes yoga and meditation may preserve telomere length and telomerase activity by reducing oxidative stress and chronic inflammation, supporting anti-aging effects at the cellular level. Sanatanodaya Google Scholar https://sanatanodaya.com/index.php/dj/article/view/97
Effectiveness of adjunctive traditional Chinese medicine in reducing psychiatric rehospitalization in patients with schizophrenia: A nationwide cohort study in Taiwan Soong, WT; Chung, CH; Tzeng, NS; Chien, WC; Huang, YC 2026 Other Linking Intervention and Impact Yes Retrospective nationwide matched cohort in Taiwan (2000-2021) of 4,578 adults with newly diagnosed schizophrenia, comparing Chinese herbal medicine users with propensity-matched non-users No Yes Mental Health Favorable Adjunctive TCM use was associated with significantly lower risk of schizophrenia-related rehospitalization (adjusted hazard ratio 0.601; 95% CI 0.482-0.863; p < 0.001), plus shorter average length of stay and fewer cumulative psychiatric admissions over 5 years. Integrative Medicine Research Google Scholar 10.1016/j.imr.2026.101306 https://www.sciencedirect.com/science/article/pii/S2213422026000235
Clinical outcomes and safety of Chinese herbal medicine in the treatment of hyperuricemia: A retrospective real-world study Long, Z; Zhao, H; Yin, Y; Sun, Y; Shen, P; Lin, H; Liu, J; Zhan, S; Jiang, Z; Sun, F 2025 Other Linking Intervention and Impact Yes Retrospective new-user cohort of 40,653 patients with hyperuricemia (China, 2015-2024): 35,511 Chinese herbal medicine users vs 5,142 benzbromarone users, propensity-matched Yes Favorable Gouty arthritis incidence was 34.43 vs 58.00 per 1,000 person-years among Chinese herbal medicine versus benzbromarone users, a 43% relative risk reduction (HR 0.57), with comparable drug-induced liver injury risk (HR 1.18). Phytomedicine Google Scholar 10.1016/j.phymed.2025.157231 https://www.sciencedirect.com/science/article/pii/S0944711325008700
P0903 Structured yoga practices significantly improve quality of life in patients with Ulcerative Colitis in clinical remission: a randomized controlled trial Kalum, JDBS; Narang, H; Virmani, S; Shukla, A; Verma, M; Madan, D; Kumar, P; Mathew, D; Prasad, S; Mubunnu, M 2025 RCT Linking Intervention and Impact Yes RCT in 100 patients with ulcerative colitis in remission: IBD-specific yoga therapy (45 minutes/day, 5 days/week) vs brisk walking, both alongside standard treatment, for 6 months Yes Autoimmune Disease Favorable At 6 months the yoga group had lower perceived stress (p=0.03) and anxiety (p=0.01) and higher physical (p=0.014) and psychological well-being (p=0.001) than the walking group; social domain scores were similar. One patient in each arm relapsed. Journal of Crohn's and Colitis Google Scholar https://academic.oup.com/ecco-jcc/article/19/Supplement_1/i1707/7968027
Effect of ozone therapy on oxidative stress indices in chronic inflammatory diseases: a systematic review and meta-analysis of randomized clinical trials Alimohammadi, M; Khoshnazar, SM; Khajehpour, H; Izadi, M; Einollahi, B; Hushmandi, K 2025 Meta Analysis Linking Intervention and Impact Yes Meta-analysis of 12 RCTs (846 participants) of ozone therapy versus control on oxidative stress markers in patients with chronic inflammatory diseases. Yes Diabetes Autoimmune Disease Neutral No significant difference in oxidative stress parameters overall versus controls. Subgroup analyses found increased SOD activity in type 2 diabetes (WMD 7.59) and arthritis (WMD 9.21) and reduced AOPP at doses >=20 ug/ml (WMD -5.15), but heterogeneity was very high (I2 67-98%). Advances in Redox Research Google Scholar 10.1016/j.arres.2025.100143 https://www.sciencedirect.com/science/article/pii/S2667137925000244
Does the practice of yoga lead to patient-oriented improvements in PCOS? Aly, B; Nagarajan, P 2025 Other Linking Intervention and Impact Yes Evidence summary (clinical inquiry) on whether yoga therapy produces patient-oriented improvements in polycystic ovary syndrome, drawing on a meta-analysis and RCTs with small sample sizes. Yes Favorable Yoga therapy may improve menstrual cycle irregularity, hirsutism, and anthropometric parameters of PCOS, but did not improve quality of life. Underlying evidence is a meta-analysis and RCTs with small sample sizes. Evidence-Based Practice Google Scholar 10.1097/EBP.0000000000002405 https://doi.org/10.1097/EBP.0000000000002405
Comparative Efficacy of Homeopathy and Integrated Yoga Therapy in Polycystic Ovary Syndrome Lobo, A; D’Mello, J; D’Cunha, P 2025 Other Linking Intervention and Impact Comparison of homeopathy alone versus combined homeopathy plus integrated yoga therapy for menstrual regularity and hyperandrogenism in women with PCOS (about 31 participants per group). Study design and allocation method are not stated. Yes Neutral Regular menstruation was achieved in 64.52% of the homeopathy-plus-yoga group versus 61.29% of the homeopathy-only group, with no statistically significant difference (chi-square = 0.793); no adverse effects were reported. The International Journal of Biotechnology and Biomedicine Google Scholar 10.31674/ijbb.2025.v02i03.001 https://doi.org/10.31674/ijbb.2025.v02i03.001
The Role of Yoga in Mitigating Pulmonary Function and Psychological Decline Due to Air Pollution: A Randomized Controlled Trial in Delhi-NCR. Kakkar, S; Basu, N; Sharma, V; Jaiswal, G 2025 RCT Linking Intervention and Impact Yes 12-week RCT in 86 adults aged 18-50 chronically exposed to air pollution in Delhi-NCR: structured Hatha yoga (60-minute sessions of asanas, pranayama, and meditation, 5 days/week) versus control, assessed by spirometry, PSS, DASS-21, and SGRQ. No Yes Favorable Yoga group improved on pulmonary function (FVC +0.83 L, FEV1 +0.93 L, PEFR +2.06 L/sec), psychological measures (DASS-21, PSS), and quality of life (SGRQ), while controls deteriorated on all outcomes. Advances in Mind-Body Medicine Google Scholar https://advances-journal.com/research/the-role-of-yoga-in-mitigating-pulmonary-function-and-psychological-decline-due-to-air-pollution-a-randomized-controlled-trial-in-delhi-ncr/
Effect of a structured yoga intervention on thyroid function and symptom profile in a woman with primary hypothyroidism: A case report Poornima, P; Mazooda, M; Preethika, P; hafeefa Mehabooba, S; Sanathani, S; Roopasena, R; Singh, P; Annamalai, A 2026 Case Study Linking Intervention and Impact A 42-year-old woman with primary hypothyroidism participated in a structured yoga intervention for 3 months alongside continued conventional medical management; assessed on thyroid function tests and symptom profile. Yes Favorable TSH fell and T3 and T4 rose after the intervention, with self-reported improvements in energy, sleep quality, and menstrual regularity and no adverse events. Indian Journal of Integrative Medicine Google Scholar https://mansapublishers.com/ijim/article/view/8017
Yoga as a Non Pharmacological Intervention to Overcome Weight Gain in 3 Month Injectable Contraceptive Acceptors Zulhijriani, Z; Sari, II; Lestari, NA 2025 Other Linking Intervention and Impact Pre-experimental one-group pretest-posttest study (no control) in 56 women using the 3-month DMPA injectable contraceptive: yoga three times a week for four weeks, with body weight measured before and after and analyzed by paired t-test. Yes Favorable Body weight fell significantly after the four-week yoga intervention (p < 0.001). Proceeding Cendekia International Conference Health and Technology Google Scholar https://proceedings.centamaku.ac.id/article/view/235
Effects of Iyengar Yoga and Yoga Nidra on inflammation, sleep, and disability in older men with chronic low back pain Samal, AN; Kanagasabapathy, S; Elayaraja, M; Govindasamy, K; Valappil, INK; Karmakar, D; Camenidis, CM; Boby, FA; Geantă, VA 2025 RCT Linking Intervention and Impact Yes RCT in 55 men aged 55-65 with chronic low back pain: 3-month combined Iyengar yoga and Yoga Nidra program (n=28) versus standard care (n=27), with blinded assessment of inflammatory markers (primary) plus sleep, disability, depression, and pain catastrophizing. No Yes Favorable Intervention group showed significantly greater reductions in hs-CRP, IL-6, and TNF-alpha and greater improvements in sleep quality, functional disability, depressive symptoms, and pain catastrophizing, all at p < 0.001, with no serious adverse events. Retos: Nuevas Tendencias en Educacion Fisica, Deporte y Recreacion Google Scholar https://www.researchgate.net/publication/403305647
Yoga practice duration and its influence on type 2 diabetes management: A meta-analysis of Asian population Mahajan, A; Shah, J; Muley, A 2026 Meta Analysis Linking Intervention and Impact Yes Meta-analysis of 22 RCTs (1,720 participants aged 18-65, Asian populations) comparing yoga intervention durations of under 12 weeks versus 12 weeks or more for type 2 diabetes outcomes. No Yes Diabetes Favorable Interventions of 12 weeks or more significantly reduced HbA1c (SMD -0.70, p=0.0001), total cholesterol, and LDL and raised HDL; shorter interventions were significant only for weight. Heterogeneity was high throughout (I2 79-93%). iScience Google Scholar https://www.cell.com/iscience/fulltext/S2589-0042(26)00663-2
Assessing the role of yoga in managing blood pressure: A systematic review of evidence Fatima, A; Akhter, M; Mitra, R; Sharma, M 2025 Systematic Review Linking Intervention and Impact Yes Systematic review of evidence on yoga for blood-pressure management in adults with prehypertension/hypertension (conference abstract). Yes Yes Cardiovascular Disorders Favorable Review concludes yoga is associated with reduced blood pressure and may be a useful complementary intervention for hypertension (consistent with meta-analyses showing modest SBP/DBP reductions). APHA Annual Meeting (conference abstract) Google Scholar https://apha.confex.com/apha/2025/meetingapi.cgi/Paper/565137?filename=2025_Abstract565137.html&template=Word
Yoga Prana Vidya Healing as Complementary Medicine in Scalp Psoriasis: A Srinivasu, P; Nanduri, VS 2026 Case Study Linking Intervention and Impact Case report: 39-year-old man with seven-year scalp psoriasis treated with Yoga Prana Vidya energy-healing protocols, yogic breathing and meditation over three months Yes Autoimmune Disease Favorable Patient reported 70-80% symptom improvement at two months and 95% resolution by month three, with improved confidence, energy, and stress, sustained at three-month follow-up. International Journal of Medical Science and Health Research Google Scholar https://www.yogapranavidya.com/publications/yoga-prana-vidya-healing-as-complementary-medicine-in-scalp-psoriasis-a-case-report/
The Effect of Spiritual Emotional Freedom Technique (SEFT) on Anxiety Levels of Pre-Caesarean Section Mothers Sukardi, TA; Lombonaung, E; Sabban, F 2026 Other Linking Intervention and Impact One-group pre-post study of the Spiritual Emotional Freedom Technique in 15 pre-caesarean mothers in Ambon, Indonesia No Yes Favorable Anxiety levels decreased significantly after the SEFT intervention (Wilcoxon p = 0.001). Authors conclude SEFT is effective at reducing preoperative anxiety and can be considered a complementary nursing intervention. Int J Educ Psychol Sci Google Scholar 10.59890/ijeps.v4i1.308 https://doi.org/10.59890/ijeps.v4i1.308
Efficacy and safety of hyperbaric oxygen therapy in ligament and tendon injuries: a systematic review Babel, S; Bosco, G; Camporesi, E 2025 Systematic Review Linking Intervention and Impact Yes Systematic review (six databases, 1999-2024) of hyperbaric oxygen therapy for ligament and tendon injuries, spanning animal and human studies Yes Favorable Review: hyperbaric oxygen therapy improved healing of ligament and tendon injuries across histological, biomechanical, and functional outcomes, whether adjunctive or standalone. Protocols varied widely and larger standardized human trials are needed. Eur J Transl Myol Google Scholar 10.4081/ejtm.2025.14016 https://doi.org/10.4081/ejtm.2025.14016
Symptom–Remedy: A Homeopathic Approach to Sleep Disorders Tosheva, G 2025 Other Linking Intervention and Impact Narrative review of the symptom-remedy principle in individualized homeopathy for acute and chronic sleep disorders, drawing on RCTs, pilot studies and case reports Favorable Narrative review: individualized symptom-to-remedy homeopathic prescribing was associated with improved sleep quality, reduced concomitant pharmacotherapy, and better tolerability. Author concludes it is a potentially safe alternative for sleep disorders and calls for larger studies. Knowledge - International Journal Google Scholar https://ojs.ikm.mk/index.php/kij/article/view/7725
Actions to control the fear of falling in older people: An umbrella review Oliveira, ARC; Magueja, CMP; de Almeida, AMG 2026 Systematic Review Linking Intervention and Impact Yes Umbrella review of 25 secondary studies on interventions to control fear of falling in adults 60 and over, spanning physical therapy, CBT, combined strategies, multifactorial programs and technology Yes Yes Favorable Umbrella review of 25 secondary studies: holistic exercises (Tai Chi, yoga, Pilates) were most effective for mitigating fear of falling in older adults, with multimodal and combined physical-cognitive approaches also beneficial and CBT effective alongside exercise; evidence for exergames was inconclusive. Arch Gerontol Geriatr Google Scholar 10.1016/j.archger.2025.106087 https://www.sciencedirect.com/science/article/pii/S0167494325003449
Use of yoga in acute mental health inpatient settings: a systematic review Wu, C; Waldmann, J; McPherson, J; Korman, N; Parker, S 2025 Systematic Review Linking Intervention and Impact Yes Systematic review of 15 studies (n=2,016) of yoga in acute psychiatric inpatient settings, covering both effectiveness and implementation; narrative synthesis Yes Mental Health Favorable Yoga was feasible and acceptable in inpatient psychiatric settings with few adverse events, producing subjective anxiety improvement, and one RCT showed sustained gains in physical health, functioning, and quality of life. Results were mixed for depressive and psychotic symptoms, and limited evidence quality prevents conclusions on effectiveness. Ment Health Phys Act Google Scholar 10.1016/j.mhpa.2024.100666 https://www.sciencedirect.com/science/article/pii/S1755296624000930
Effect of Yoga on Psychological and Spiritual Outcomes in Cancer Patients: A Systematic Review and Meta-Analysis of Randomized Controlled Trials with Meta-Regression Takemura, N; Chung, KCW; Kwok, JYY; Fong, DYT 2025 Meta Analysis Linking Intervention and Impact Yes Meta-analysis of 55 RCTs (n=3,608) of yoga vs control on psychological, spiritual and emotional well-being in adults with cancer, with meta-regression Yes Yes Cancer Favorable Yoga largely reduced anxiety (g -0.82) and moderately-to-largely reduced depression (g -0.62), and mildly improved spiritual (g 0.31) and emotional well-being (g 0.23). Heterogeneity was high for the anxiety and depression estimates (I2 85-88%). Psychother Psychosom Google Scholar 40288356 10.1159/000545697 https://doi.org/10.1159/000545697
Does Yoga Therapy Improve Range of Motion in Shoulders of Women Recovering from Breast Cancer Surgery? A Randomised Controlled Trial Lam, WWT; Ng, DWL; Fielding, R; Fong, DYT; Kwong, A; Soong, I; Chan, WWL; Chun, VOK; Fung, S 2025 RCT Linking Intervention and Impact Yes Three-arm RCT in 444 Chinese women with early-stage breast cancer post-treatment: 12-week yoga vs relaxation (active control) vs postoperative exercise DVD (passive control) Yes Cancer Favorable Versus passive control, the yoga group significantly improved shoulder rotation flexibility (p=0.004) and right back-scratch scores (p=0.013), with no difference in left-hand back scratch or in secondary outcomes (quality of life, fatigue, pain, sleep, anxiety, depression). Sports Med Open Google Scholar 10.1186/s40798-025-00943-5 https://doi.org/10.1186/s40798-025-00943-5
Yoga in Obesity Management: Reducing cardiovascular risk and enhancing well-being-A review of the current literature Inbaraj, G; Bajaj, S; Misra, P; Thapa, A; Ghosal, A; Sharma, U; Pobbati, H; Hashmi, I; Bansal, B; de Vos, J 2025 Systematic Review Linking Intervention and Impact Yes Review of literature through March 2024 on yoga as a complementary intervention in obesity management and cardiovascular risk reduction Favorable Review: yoga consistently reduced BMI, waist circumference, and body fat, with improvements in blood pressure, cholesterol, endothelial and autonomic function, stress management, and psychological well-being. Authors conclude yoga is a promising adjunct for obesity management and CVD risk reduction. Curr Probl Cardiol Google Scholar 40132783 10.1016/j.cpcardiol.2025.103036 https://pubmed.ncbi.nlm.nih.gov/40132783/
Effect of Yoga Therapy and Music Therapy in Stabilizing C-Reactive Protein Among Hypertensive Middle-Aged Men. Swaminathan, AC; Rajamanickam, R; Chokkalingam, D; Gunasekaran, B; Palanisamy, U; Badri, K; Kambitta Valappil, IN; Karmakar, D; Yenes, R; Govindasamy, K 2025 Other Linking Intervention and Impact Yes Single-group pre-post study of a 12-week integrated yoga and music therapy program in 36 middle-aged men with hypertension No Yes Cardiovascular Disorders Favorable Combined yoga and music therapy significantly reduced hs-CRP (-1.50 mg/L), IL-6 (-1.56 pg/mL), TNF-alpha (-4.12 pg/mL), and systolic (-11.59 mmHg) and diastolic BP (-5.06 mmHg), all p<0.001, with substantial effect sizes (0.71-0.78). Fizjoter Pol Google Scholar 10.56984/8ZG007DJX8D https://fizjoterapiapolska.pl/en/article/wplyw-jogi-i-muzykoterapii-na-poziom-bialka-c-reaktywnego-u-mezczyzn-w-srednim-wieku-z-nadcisnieniem-jednoseryjne-badanie-quasi-eksperymentalne/
The Effect of Yoga on Depression, Anxiety, and Stress During Pregnancy and Postpartum: A Systematic Review and Meta-Analysis Ranjbar, M; Abdolalipour, S; Payne, E; Hassanzadeh, R; Maghalian, M; Mirghafourvand, M 2026 Meta Analysis Linking Intervention and Impact Yes Meta-analysis of 35 studies (23 RCTs, 12 quasi-experimental) of yoga for anxiety, depression and stress during pregnancy and the postpartum period No Yes Favorable Yoga reduced prenatal depression (SMD -0.98), anxiety (SMD -1.15), and stress (SMD -0.88), driven by women without pre-existing symptoms; no significant effect among those with existing symptoms. Certainty of evidence was low to very low. Best Pract Res Clin Obstet Gynaecol Google Scholar 10.1016/j.bpobgyn.2026.102730 https://www.sciencedirect.com/science/article/abs/pii/S1521693426000301
Yoga in autoimmune disorders: a systematic review of randomized controlled trials Baishya, A; Sharma, S; Hazarika, D; Saini, S; Sharma, H; Metri, K 2025 Systematic Review Linking Intervention and Impact Yes Systematic review of 26 RCTs (n=1,960) of yoga interventions of 8 weeks or more in multiple sclerosis, rheumatoid arthritis, ankylosing spondylitis, inflammatory bowel disease and autoimmune periodontitis Autoimmune Disease Favorable Yoga showed positive evidence for fatigue, balance, quality of life, and depression in multiple sclerosis; inflammatory biomarkers and depression in rheumatoid arthritis; physical function and disease activity in ankylosing spondylitis; and clinical attachment loss in periodontitis. No adverse events; effectiveness assessed by vote counting rather than pooled estimates. Ann Behav Med Google Scholar 10.1093/abm/kaaf049 https://doi.org/10.1093/abm/kaaf049
Yoga Intervention and Inflammatory Homoeostasis in Breast Cancer Patients Kaje, KC; Dsilva, F; Shetty, PK; Mohan, R; Kumar, S; Dsouza, N; D’souza, C; Kalladka, SS; Alagundagi, DB; Kalladka, K 2025 Prosp Cohort Study Linking Intervention and Impact Yes Prospective non-randomised controlled study of yoga in 44 newly diagnosed breast cancer patients (stages II-IV) during neoadjuvant chemotherapy and surgery Cancer Neutral Significant within-group reductions in serum TNF-alpha, IL-1-beta, and IL-6 in the yoga group with no change in controls, but between-group differences were not significant. Non-randomised, n=44, biomarker endpoints only. Indian J Palliat Care Google Scholar 10.25259/IJPC_181_2024 https://doi.org/10.25259/IJPC_181_2024
Hatha Yoga And YogaCue Improve Peak Power And Functional Outcomes In Older Adults. Simlote, S; Martinez, KJ; Wang, J; Jiang, H; Ebner, N; Sarama, J; Gastaldo, R; Calaway, C; Weber, M; Signorile, JF 2025 Other Linking Intervention and Impact Yes Trial of Hatha yoga with 'YogaCue' on peak power and functional outcomes in older adults (conference abstract). Yes Yes Favorable Hatha yoga (with YogaCue) improved peak power and functional outcomes in older adults (per title; conference abstract, limited detail). Medicine & Science in Sports & Exercise Google Scholar https://www.ovid.com/jnls/acsm-msse/abstract/10.1249/01.mss.0001160240.26773.de~hatha-yoga-and-yogacue-improve-peak-power-and-functional?redirectionsource=fulltextview
Effectiveness and safety of yoga-based interventions in the management of atrial fibrillation: a systematic review Elamir, AAKM; Adam, YAM; Abdelrahman, IMO; Elnosh, HAA; Mohammad, MAA; Ahmed, OAO; Ahmed, RAO; Ahmed, AAA; Ahmed, RAA; Farah, AFA 2026 Systematic Review Linking Intervention and Impact Yes Yoga-based interventions delivered as an adjunct to standard care for adults with atrial fibrillation, reporting arrhythmia symptoms, cardiovascular parameters, quality of life, and psychological health. Yes Cardiovascular Disorders Favorable Two studies showed significant reductions in AF symptom frequency and three in resting heart rate and blood pressure; all reported improved quality of life and two reduced depression and anxiety. No adverse events, high adherence, and moderate risk of bias across studies. Sport Sciences for Health Google Scholar 10.1007/s11332-025-01641-1 https://doi.org/10.1007/s11332-025-01641-1
Effects of prenatal yoga on birth outcomes in nulliparous women: a systematic review and meta-analysis of randomized controlled trials Chen, F; Yu, H; Peng, S 2025 Meta Analysis Linking Intervention and Impact Yes Prenatal yoga classes and practice (moderate aerobic activity with mindfulness-based stress reduction, diaphragmatic breathing, and pelvic-floor conditioning) in addition to general nursing, compared with general nursing alone, in nulliparous women; 14 RCTs pooled with 3,637 women. Yes Favorable Meta-analysis: versus general nursing, yoga reduced cesarean section (RR 0.45), premature birth (RR 0.29), and perineal laceration (RR 0.41, all p<0.01) and shortened total labor time (MD -2.10, p<0.0001). Risk of bias was generally low. BMC Pregnancy and Childbirth Google Scholar 10.1186/s12884-025-08279-4 https://doi.org/10.1186/s12884-025-08279-4
Effect of Integrated Yoga and Naturopathy Intervention in Patient with PostViral Arthralgia: A Case Report Taz, MA; Nivethitha, L; Manavalan, N 2024 Case Study Linking Intervention and Impact A 42-year-old female with primary hypothyroidism received a therapeutic diet for 21 days alongside prescribed allopathic medication; assessed pre-post on BMI, thyroid profile, and quality of life (SF-12). Yes Favorable Over 21 days, BMI fell from 27 to 23 kg/m2, T3 rose from 34.8 to 117.9 ng/dl, T4 from 1.0 to 13.2 ug/dl, TSH fell from 39.540 to 0.591 uIU/ml, and SF-12 quality of life rose from 72 to 98. Indian Journal of Integrative Medicine Google Scholar https://mansapublishers.com/index.php/ijim/article/view/4798
P1143 Effect of a Structured Yoga Module as an Adjunct to Standard Care in Mild–Moderate Ulcerative Colitis: A Prospective Observational Pilot of 15 Patients Vats, A 2026 Prosp Cohort Study Linking Intervention and Impact Yes Structured 8-12 week yoga module as an adjunct to standard medical therapy in 15 patients with mild-moderate ulcerative colitis, systematically avoiding poses known to aggravate symptoms Yes Autoimmune Disease Favorable Yoga reduced stool frequency by a mean of 1.8/day, with improvement in bleeding (10/15 patients), mucus discharge (12/15), and abdominal cramps (11/15). Postures involving abdominal decompression and pelvic floor relaxation helped most, while those requiring abdominal strain worsened symptoms. Journal of Crohn's and Colitis Google Scholar https://academic.oup.com/ecco-jcc/article/20/Supplement_1/jjaf231.1324/8433892
Yoga it's application in surgery: A review study Shende, G; Mohan, D; Khandate, M 2026 Other Linking Intervention and Impact Conceptual and narrative review of yoga practices (Asana, Pranayama, Dhyana) as an adjunct in perioperative surgical care, drawing on classical yoga texts, Ayurvedic literature, and modern studies to address preoperative preparation, postoperative recovery, and rehabilitation. Yes Favorable Yoga practices reduced preoperative anxiety and improved respiratory efficiency and autonomic balance. Postoperatively, yoga supported pain reduction, wound healing, pulmonary function, early mobilization and psychological well-being, contributing to faster recovery and improved quality of life. Journal of Ayurveda and Naturopathy Google Scholar https://www.bing.com/ck/a?!&&p=9f82886b8773c06f51f7f43dff998aeae8ed502bdda5b8595cef8422ab0b0003JmltdHM9MTc4NDc2NDgwMA&ptn=3&ver=2&hsh=4&fclid=3fab81b3-b0ee-6b05-0a3c-96b9b1496ac7&psq=Yoga+it%27s+application+in+surgery%3a+A+review+study+Shende%2c+Girish%3b+Mohan%2c+Dheeraj%3b+Khandate%2c+Maheshchandra%3b&u=a1aHR0cHM6Ly93d3cuYXl1cnZlZGpvdXJuYWwubmV0L2FyY2hpdmVzLzIwMjYvdm9sM2lzc3VlMS9QYXJ0Qi8zLTEtMTYtNTg3LnBkZg
Prenatal Gentle Yoga Improves Sleep Quality in Third-Trimester Pregnancy: Clinical Transition Analysis Tumani, YK; Khaerah, U; Taurisa, A 2026 Other Linking Intervention and Impact Four structured prenatal gentle yoga sessions over two weeks for 33 third-trimester pregnant women with Pittsburgh Sleep Quality Index (PSQI) scores above 5, delivered in a primary healthcare setting (Puskesmas Biromaru, Indonesia), May to July 2025. Sleep quality measured by PSQI pre and post. Yes Favorable Mean PSQI score fell from 9.12 (SD 2.31) to 5.08 (SD 1.94), a mean difference of 4.04 (95% CI 3.37-4.71; p < 0.001) with a large effect size (Cohen's d = 1.72). The proportion classified as having good sleep quality rose substantially. Karismavit Health Journal Google Scholar https://khj.karismavit.id/index.php/khj/article/view/11
The right treatment for the right patient: utility of exergaming and medical yoga for heart failure patients Tremblay, R; Shivgulam, ME; Halliwell, C; O’Brien, MW 2025 Other Linking Intervention and Impact No Invited commentary on a 3-month RCT in heart failure patients comparing exergaming, yoga, and an active control receiving physical activity advice, with follow-up to 12 months Yes Cardiovascular Disorders Neutral The underlying trial found no between-group differences on any outcome. Within groups, exergaming and yoga each improved 6-minute walk distance, fatigue, and shortness of breath, with exergaming also improving physical and yoga emotional quality of life. European Journal of Cardiovascular Nursing Google Scholar 10.1093/eurjcn/zvaf021 https://doi.org/10.1093/eurjcn/zvaf021
Yoga as an Intervention for Tobacco Cessation-A Randomized Controlled Trial Lama, S; Haldar, P; Shukla, A; Chhabra, V; Shukla, A; James Vibin, A; Jat, MS; Dhanlika, D; Sagar, R; Sharma, G 2025 RCT Linking Intervention and Impact No Randomized, open, blinded-endpoint trial in healthy adult tobacco users (18-65): yoga (n=64) vs exercise (n=66); primary outcome 7-day point-prevalence abstinence at 6 months (cotinine-validated), plus quality of life and DASS. No Yes Alcohol/Drug Dependence Favorable RCT of 130 adult tobacco users: 7-day point-prevalence abstinence was 22% with yoga vs 9.1% with exercise (OR 2.8, p=0.043), with significant between-group gains in quality of life and reductions in stress, anxiety (p<0.001), and depression (p=0.008). SSRN Preprint (Preprints with The Lancet) Google Scholar 10.2139/ssrn.5109781 https://papers.ssrn.com/sol3/papers.cfm?abstract_id=5109781
Sperm DNA fragmentation and yoga: A narrative review on enhancing male reproductive health Tiwari, P; Yadav, A; Kumari, D; Mishra, R; Dada, R 2025 Other Linking Intervention and Impact Yes Narrative review of mechanisms by which yoga may enhance male reproductive health, focused on sperm DNA fragmentation and oxidative stress. No Yes Favorable Review concludes yoga enhances mitochondrial function and antioxidant capacity, reduces oxidative sperm-DNA damage (e.g., 8-OHdG), and promotes DNA repair, presented as a promising adjunct therapy for male infertility. Pathol Res Pract Google Scholar 41108985 10.1016/j.prp.2025.156269 https://pubmed.ncbi.nlm.nih.gov/41108985/
Yoga, sexual dysfunction, and female concussions: a mind-body pilot intervention Anto-Ocrah, M; Garth, H; Pukall, C; Levine, MD; Sherman, S; Snedaker, K 2026 Other Linking Intervention and Impact Yes Single-arm pilot of a brain injury-tailored yoga program in 12 women with post-concussion symptoms (6 completed), with outcomes at 1 and 5 weeks Yes Neurologic Disorders Favorable Of 12 enrolled, 6 completed at least three sessions. At 1 week post-intervention participants reported substantial improvements in sexual functioning and mood: effect sizes were large for sexual function (change -0.50), medium for anxiety (-0.30), and small for PTSD (-0.15) and depression (0.05). At 5 weeks scores declined slightly but remained above baseline, with sexual function retaining a medium effect size (-0.34). Participant satisfaction was high (mean 8.7/10). Authors conclude yoga has potential to improve women's sexual functioning after concussion and offers a non-pharmacological option, but larger randomized trials are needed. Front Neurol Google Scholar 10.3389/fneur.2026.1705668 https://doi.org/10.3389/fneur.2026.1705668
Effect of Raj Yoga Meditation on Self-Compassion and Psychological Well-Being among Older Adults: A Quantitative Study Shrivastava, R; Vijayaraghavan, DS 2026 Other Linking Intervention and Impact Single-group pre-test/post-test quantitative study of a structured Raj Yoga Meditation (non-physical, cognitive-awareness meditation) intervention in 60 community-dwelling older adults aged 60+, measuring self-compassion and psychological well-being on standardized scales. Yes Yes Favorable Post-test mean scores for both self-compassion and psychological well-being were significantly higher than pre-test scores following the Raj Yoga Meditation intervention (paired-sample t-tests). A significant positive relationship was observed between self-compassion and psychological well-being. Authors conclude Raj Yoga Meditation is an effective psychosocial intervention for older adults and support its inclusion in mental health and geriatric care programmes. WitWaves J Multidiscip Res Google Scholar 10.64175/wjmr.vol.3.issue1.1 https://www.witwaves.in/journal/article/9ebf0973-7a51-4d61-bdd1-14d9d8309d4a
PHYSIOLOGICAL BASIS AND HEALTH BENEFITS OF YOGA Qairunnisa, S 2025 Other Linking Intervention and Impact Narrative review (short communication) of clinical and experimental literature on physiological parameters influenced by yoga practices, including asanas, pranayama, and meditation. Favorable Yoga practice is associated with enhanced parasympathetic activity, improved heart rate variability, reduced blood pressure, improved pulmonary function, and decreased stress biomarkers including cortisol; increased GABA activity has also been reported. Authors conclude yoga exerts measurable systemic physiological effects through autonomic modulation and neuroendocrine regulation and is a safe, cost-effective adjunct in preventive and lifestyle medicine. Narrative review; no pooled effect estimates or defined study population reported. Nat J Med Res Yoga Sci Google Scholar 10.65786/k185hg76 https://njmrys.com/index.php/files/article/view/38
The Effect of Prenatal Yoga on Sleep Quality of Pregnant Women in the Third Trimester at PMB Restu Bunda Wati, R; Kusumastuti, K; Sofiana, J; Tyas, SF 2025 Other Linking Intervention and Impact Quasi-experimental one-group pre-post study of gentle prenatal yoga (five sessions over two weeks) in 40 third-trimester pregnant women in Kebumen, Indonesia No Yes Favorable Poor sleep quality fell from 85% of participants before the intervention to 7.5% after, with 92.5% reporting good sleep quality post-intervention; the improvement was statistically significant (Wilcoxon signed-rank Z = -5.868, p = 0.001). Authors recommend gentle prenatal yoga as a safe, effective complementary therapy in antenatal care. Single-group design with no control arm; n = 40 at one site. Placentum Google Scholar https://jurnal.uns.ac.id/placentum/article/view/107616
Integrating Traditional Yogic Practices with Modern Exercise Science for Sustainable Wellness in Aging Populations Geetha, K; Karpagam, M 2025 Other Linking Intervention and Impact Conceptual synthesis paper proposing an integrated model that combines traditional yogic practices (asanas, pranayama, dhyana/meditation) with structured resistance-aerobic training for older adults, referencing a 16-week hybrid yoga-exercise intervention. Yes Favorable Authors report that the integrative 16-week yoga plus resistance-aerobic model improved cardiovascular efficiency, balance, muscle endurance, and psychological resilience, with gains in VO2 max, heart rate variability, cortisol regulation, neuroplasticity, emotional stability, and functional independence, and greater intrinsic motivation for long-term adherence. They conclude hybridized yoga-exercise interventions offer a sustainable, culturally competent model of preventive geriatric care. J Yoga Sports Health Sci Google Scholar https://aasrresearch.com/index.php/ayshs/article/view/406
Yoga Interventions and Randomised Controlled Trials: Key Issues and the Centered Impact on Sedentary Lifestyle-Associated Cardiometabolic Disorders Radhamani, R; Diwakar, S 2026 Meta Analysis Linking Intervention and Impact Yes Meta-analytical review of RCTs on Hatha yoga for sedentary-lifestyle-associated cardiometabolic disorders and non-communicable diseases (blood pressure, glycemic control, lipids). Yes Yes Cardiovascular Disorders Diabetes Favorable Yoga training improved stress-related physiological responses, reduced hypertension risk, served as a complementary intervention for diabetes management, and regulated lipid biomarkers associated with cardiometabolic disorders. Front Clin Diabetes Healthc Google Scholar 10.3389/fcdhc.2026.1805160 https://doi.org/10.3389/fcdhc.2026.1805160
Neuroplasticity and Yoga: How Practice Reshapes the Brain Bala, MN; Ahluwalia, PS 2025 Other Linking Intervention and Impact Narrative review of structural and functional neuroimaging (MRI, fMRI) evidence on yoga-induced neuroplasticity in healthy adults, older adults at risk of cognitive decline, and clinical neurological populations Yes Yes Neurologic Disorders Favorable Structural MRI studies consistently show increased gray matter volume in the hippocampus, insula, and prefrontal cortex among long-term yoga practitioners, and functional imaging shows enhanced connectivity in networks for attention, emotional regulation, and self-awareness. These changes correlate with improved cognitive performance, stress resilience, and emotional well-being, and appear age-, experience-, and frequency-dependent. Authors conclude yoga is a promising non-pharmacological intervention for brain health across the lifespan, with particular relevance to preventing age-related cognitive decline. Narrative review; no pooled effect estimates reported. Sanatanodaya Google Scholar https://sanatanodaya.com/index.php/dj/article/view/91
Effects Of Structured Yoga Practice On Pulse Rate And Life Satisfaction Among Later Adult Infertile Women Srividhya, K; Malaialagu, P; Murugesan, S 2026 RCT Linking Intervention and Impact RCT in 60 infertile women aged 30-40 in Chennai, India: 12 weeks of structured yoga (60 minutes/day, 5 days/week) vs usual care No Yes Favorable Compared with usual care, 12 weeks of yoga significantly reduced pulse rate (F=32.28, p<0.001) and improved life satisfaction (F=285.09, p<0.001), with large effect sizes (eta-squared >0.35). Authors conclude yoga effectively relieves the combined physiological and psychological strain of infertility and recommend incorporating it into fertility treatment protocols. The enrolled sample was aged 30-40. Int J Signal Image Sci Google Scholar 10.29284/5tkzmd10 https://www.xlescience.org/index.php/IJASIS/article/view/1420
Study on the Effect of Prenatal Gentle Yoga Poses on the Level of Discomfort during the First Trimester of Pregnancy Hamidah, R; Inayah, IM; Safniah, R 2025 Other Linking Intervention and Impact Quasi-experimental pre-post study with control group in 30 first-trimester pregnant women in Mataram, Indonesia: prenatal gentle yoga vs no intervention No Yes Favorable The prenatal gentle yoga group experienced a significant reduction in first-trimester discomfort (nausea, dizziness, fatigue) compared with the control group. Authors conclude prenatal gentle yoga is an effective method for reducing discomfort and improving physical and mental well-being during pregnancy. Total n = 30 across both arms. Media of Health Research Google Scholar 10.70716/mohr.v3i1.141 https://ejournal.publine.or.id/index.php/mohr/article/view/141
Abstract P1025: Overall Effect of Stress Reduction Interventions on Cardiovascular Outcomes (Both Qualitative and Quantitative): A Systematic Review and Meta-Analysis. Damarlapally, N; Binti, NU; Winson, T; Basu, P; Tejani, V; Damarlapally, K; Thimmappa, V; Chodisetti, NSN; Khan, AF; Khena, D 2025 Meta Analysis Linking Intervention and Impact No Meta-analysis of 14 studies (n=1,180) of stress reduction interventions (CBT, yoga, MBSR, HRV biofeedback, Tai Chi) in adults with cardiovascular disease Yes Cardiovascular Disorders Favorable Meta-analysis: stress reduction interventions significantly lowered systolic (MD -9.70 mmHg) and diastolic BP (MD -5.52 mmHg, both p<0.0001), with no significant effect on heart rate, CRP, or high-frequency power. Qualitative findings favored yoga, Tai Chi, and mindfulness for inflammatory markers, cognition, quality of life, and perceived stress. Circulation Google Scholar 10.1161/cir.151.suppl_1.P1025 https://www.ahajournals.org/doi/abs/10.1161/cir.151.suppl_1.P1025
Effect of Tai Chi and Transcranial Direct Current Stimulation on Spontaneous Neural Activity in Patients with Mild Cognitive Impairment: An Exploratory Resting-State fMRI Study Liu, H; Li, H; Ren, J; Liufu, L; Yang, Y; Wu, M; Xu, Y; Tao, J 2026 RCT Linking Intervention and Impact Yes Trial combining Tai Chi with transcranial direct current stimulation (tDCS) in older adults with mild cognitive impairment; resting-state fMRI spontaneous neural activity and cognitive outcomes. Yes No Dementia Favorable Tai Chi and tDCS each significantly improved memory quotient (p<0.001) and other memory measures in mild cognitive impairment, modulating distinct cortical regions; the combination interacted significantly with immediate recall (p=0.016). Authors conclude the two have complementary neural and cognitive effects supporting a multimodal strategy to delay cognitive decline. Complement Ther Med Google Scholar 10.1016/j.ctim.2026.103382 https://www.sciencedirect.com/science/article/pii/S0965229926000658
East Meets West: Tai Chi and Health Promotion Kauffman, T; Chen, G; Kauffman, T 2025 Other Linking Intervention and Impact No Conference symposium abstract of five presentations on Tai Chi for cardiovascular, neuromuscular, cognitive and balance health, including a 12-week intervention in ankylosing spondylitis Yes Yes Autoimmune Disease Favorable The university-community intervention yielded significant improvements in sleep duration and knee osteoarthritis symptoms. The qualitative study found positive effects of lifestyle change on physical activity, diet, sleep and psychological resilience. In ankylosing spondylitis, a 12-week Tai Chi intervention showed statistically significant benefits on pain/stiffness (BASDAI), function (BASFI) and spinal mobility. The final presentation reported on Tai Chi effects on balance/falls, cognition and motor health in older adults under dual-task conditions. Innov Aging Google Scholar 10.1093/geroni/igaf122.1826 https://doi.org/10.1093/geroni/igaf122.1826
TMS Combined With Tai Chi Effect On Executive Function In Mild Cognitive Impairment Patients: 1437 Wang, M; Gu, Y; Wu, S; Zhang, Q; Yang, T 2025 RCT Linking Intervention and Impact Yes Trial of transcranial magnetic stimulation (TMS) combined with Tai Chi for executive function in patients with mild cognitive impairment (conference abstract). Yes No Dementia Favorable There were significant differences between the tai chi and control in left dorsolateral prefrontal cortex oxygenation. Medicine & Science in Sports & Expercise Google Scholar 10.1249/01.mss.0001158432.35842.34 https://www.ovid.com/jnls/acsm-msse/abstract/10.1249/01.mss.0001158432.35842.34~tms-combined-with-tai-chi-effect-on-executive-function-in?redirectionsource=fulltextview
Performance of Tai Chi Chuan and NF-κB-Driven Proinflammatory Gene Expression (IL-6, IL-1β, TNF-α) in Adult Chronic Disease Patients: A Systematic Review and Meta-Analysis of Randomized Controlled Trials Zhu, S; Wang, H 2026 Meta Analysis Linking Intervention and Impact Yes Systematic review/meta-analysis of RCTs on Tai Chi Chuan and NF-κB-driven proinflammatory cytokine gene expression (IL-6, IL-1β, TNF-α) in adult chronic-disease patients. Yes Yes Cancer Neurologic Disorders Favorable Meta-analysis of 20 RCTs: Tai Chi Chuan significantly reduced NF-kB downstream gene expression (SMD -0.48, p<0.01), including IL-6 and IL-1beta; the TNF-alpha reduction was not significant (p=0.07). Patients with endocrine and respiratory disease benefited most. Front Immunol Google Scholar 10.3389/fimmu.2026.1702830 https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2026.1702830/full
Comparison of the impact of various exercise modalities on Parkinson’s disease Park, J; Cheon, SM; Lee, MJ; Ryu, DW; Yoo, D 2025 RCT Linking Intervention and Impact Yes Multicenter open-label RCT (99 Parkinson's patients) comparing Tai Chi, strength training, yoga, and home-based exercise (12 wks supervised + 12 wks independent); motor function (MDS-UPDRS III, TUG) outcomes. Yes Yes Neurologic Disorders Favorable Over 24 weeks in Parkinson's disease, home-based exercise and Tai Chi improved MDS-UPDRS Part III motor scores and 6-minute walk distance, while strength training and yoga improved balance. No modality was superior across all outcomes; authors emphasize tailoring exercise to the patient. J Mov Disord Google Scholar 40230226 10.14802/jmd.25038 https://pmc.ncbi.nlm.nih.gov/articles/PMC12301928/
Traditional Chinese medicine in synergy with conventional therapy improves renal outcomes and provides survival benefit in patients with systemic lupus erythematosus: a cohort study from the largest health care system in Taiwan Wei, CY; Chu, CH; Shen, HS; Ko, PC; Chen, JL; Yu, HH 2025 Other Linking Intervention and Impact Yes Retrospective cohort of 10,462 newly diagnosed SLE patients in Taiwan (2005-2020) comparing 1,831 who received at least 28 days of Traditional Chinese Medicine with 7,966 who received none Yes Autoimmune Disease End-Stage Renal Disease Favorable Propensity-matched cohort (1,831 per group): adding TCM to conventional therapy was associated with lower end-stage renal disease at 6 months (aHR 0.24, p=0.02), significantly lower proteinuria through 10 years, and lower all-cause mortality (aHR 0.70). Observational design; residual confounding possible. Curr Med Res Opin Google Scholar 40079084 10.1080/03007995.2025.2478160 https://doi.org/10.1080/03007995.2025.2478160
Effect of acupoint catgut embedding for simple obesity in adults: A randomized controlled double-blind trial Yang, Q; Xu, N; Guo, L; Li, H; Li, X; Zeng, Q; Zhang, W; Li, S; Yi, W 2025 RCT Linking Intervention and Impact Yes Double-blind RCT of acupoint catgut embedding vs sham in 120 adults with simple obesity; 12-week intervention plus 12-week follow-up Yes Favorable After 12 weeks, verum auricular acupressure produced significantly greater reductions in body weight, waist/arm/thigh girth, waist-hip ratio, and appetite than sham, with effects sustained at follow-up and no safety concerns. Integr Med Res Google Scholar 40502406 10.1016/j.imr.2025.101151 https://doi.org/10.1016/j.imr.2025.101151
Efficacy of Extracorporeal Shockwave Therapy in the Management of Chronic Diabetic Foot Ulcer: A Systematic Review and Meta-Analysis Ruiz-Muñoz, M; Rueda-Zapata, L; Martinez-Barrios, FJ; Nováková, T; Lopezosa-Reca, E; Gonzalez-Sanchez, M; Fernandez-Torres, R; Galan-Mercant, A 2025 Meta Analysis Linking Intervention and Impact Yes Meta-analysis of 8 RCTs (n=672) of extracorporeal shockwave therapy vs standard of care for diabetic foot ulcer healing Yes Diabetes Favorable Meta-analysis: extracorporeal shockwave therapy as an adjunct produced higher complete diabetic foot ulcer healing than standard care alone (OR 2.75, 95% CI 1.97-3.84, p<0.01) with negligible heterogeneity. Med Sci (Basel) Google Scholar 10.3390/medsci13040219 https://doi.org/10.3390/medsci13040219
Effect of Yoga on Risk of Fall, Gait Speed, and Quality of Life in Young Old Population: A Clinical Trial Muragod, AR; Rutuja, G 2025 RCT Linking Intervention and Impact Yes 4-week RCT comparing Otago Exercise Program vs yoga (12 sessions) in young-old adults; balance (Berg Balance Scale), Timed Up-and-Go, and OPQOL-Brief quality of life. Yes Yes Favorable Both Otago Exercise Program and yoga produced significant within-group improvements in balance (BBS), mobility (TUG), and quality of life over 4 weeks. Altern Ther Health Med PubMed 40985951 https://pubmed.ncbi.nlm.nih.gov/40985951/
A Systematic Review and Meta-Analysis of Asian Exercise Techniques and Various Physical Activity Interventions in Middle and Late Adulthood Patients With Knee Osteoarthritis Qi, W; Alarcón, D; Arenilla, MJ; Yu, H; Jaenes, JC; Trujillo, M; Wilczyńska, D 2025 Meta Analysis Linking Intervention and Impact Yes Systematic review/meta-analysis comparing low-intensity physical activities (Baduanjin, Tai Chi, walking, general PA) for knee osteoarthritis symptoms in middle and late adulthood. Yes Yes Favorable Low-intensity activities (esp. Baduanjin, Tai Chi, walking) significantly reduced knee-osteoarthritis pain (d=-0.65), stiffness (d=-0.71), and improved physical function (d=-0.58). J Aging Phys Act PubMed 39773493 10.1123/japa.2024-0077 https://doi.org/10.1123/japa.2024-0077
Non-pharmacological mental health interventions for older adults in Mexico: a systematic review Zapata-De la Rosa, MF; Apolonio-Cortés, H; Ramirez-Rodriguez, R; Fernández-Demeneghi, R; Gomez Rutti, YY; Ortiz-Cruz, F; Puig-Lagunes, A 2026 Systematic Review Linking Intervention and Impact Yes Systematic review (PRISMA) of RCTs and quasi-experimental studies of non-pharmacological mental-health interventions for adults 60+ in Mexico (7 studies, N=267, mean age 71.9). Yes Yes Favorable Non-pharmacological interventions (especially physical activity) showed benefit for older adults' mental health, but national evidence was limited and fragmented (only 7 eligible studies). Front Aging PubMed 41836317 10.3389/fragi.2026.1730672 https://doi.org/10.3389/fragi.2026.1730672
Comparative effectiveness of traditional Chinese exercises for knee osteoarthritis: a systematic review and Bayesian network meta-analysis Li, Y; Zhai, Z; Guo, B; Liu, Y; An, Z; Zhai, Q 2026 Meta Analysis Linking Intervention and Impact Yes Systematic review/Bayesian network meta-analysis of 20 RCTs (1,457 patients) ranking traditional Chinese exercises (Tai Chi, Baduanjin, Wuqinxi, Yijinjing) for knee osteoarthritis in middle-aged/older adults. Yes Yes Favorable Tai Chi and Baduanjin ranked most effective for pain, joint stiffness, physical function, and quality of life; authors urge caution as studies were overwhelmingly China-based. Front Public Health PubMed 41567770 10.3389/fpubh.2025.1710610 https://doi.org/10.3389/fpubh.2025.1710610
Online Chair Yoga and Digital Learning for Rural Underserved Older Adults at Risk for Alzheimer's Disease and Related Dementias Park, J; Wiese, LAK; Holt, J 2023 RCT Linking Intervention and Impact Yes 12-week twice-weekly remotely-supervised online chair yoga vs computer brain game (after digital-literacy training) in rural underserved older adults at risk for Alzheimer's/related dementias; feasibility and cognitive/physical outcomes. Yes Yes Dementia Favorable Feasibility RCT (avg age ~67): online chair yoga was feasible and showed preliminary benefits for cognition (mini-MoCA) and mobility (TUG); telehealth delivery workable for home-bound rural older adults at risk for ADRD. Clin Gerontol PubMed 37941382 10.1080/07317115.2023.2277333 https://doi.org/10.1080/07317115.2023.2277333
The Impact of Reiki Therapy on Comfort and Quality of Life among Elderly Inmates: A Quasi-Experimental Study Kaur, J; Maheshwari, P 2025 Other Linking Intervention and Impact Yes Quasi-experimental trial of six Reiki therapy sessions over 11 days vs routine care in 230 institutionalized elderly ('inmates' = old-age-home residents); comfort and quality-of-life outcomes. Yes No Favorable The Reiki group showed significant, sustained improvements in comfort and quality of life vs routine care at all follow-ups through 3 months (p=0.001). J Pharm Bioallied Sci PubMed 41164641 10.4103/jpbs.jpbs_1036_25 https://doi.org/10.4103/jpbs.jpbs_1036_25
Psychological health outcomes of traditional Chinese exercises in older adults: a meta-analysis of randomized controlled trials Geng, D; Li, X; Shi, Y 2026 Meta Analysis Linking Intervention and Impact Yes Systematic review/meta-analysis of RCTs on traditional Chinese exercises (Tai Chi, Baduanjin, etc.) for psychological health (depression, anxiety, well-being, self-efficacy) in older adults. Yes Yes Favorable Meta-analysis of 42 RCTs (4,317 older adults): traditional Chinese exercises significantly improved depression (SMD -0.51) and other psychological outcomes (anxiety, subjective well-being, self-efficacy) vs control. PeerJ PubMed 41695691 10.7717/peerj.20773 https://doi.org/10.7717/peerj.20773
Impact of olive leaf extract on pain management and functional improvement in elderly patients with knee osteoarthritis: A randomized controlled trial Roshani, M; Delfan, B; Yarahmadi, S; Saki, M; Birjandi, M 2025 RCT Linking Intervention and Impact Yes Randomized controlled trial of olive leaf extract (oral capsule and/or topical ointment) vs control for pain and function in elderly patients with knee osteoarthritis. Yes No Favorable RCT in elderly knee-osteoarthritis patients: hydroalcoholic olive leaf extract (oral capsules +/- topical ointment) significantly reduced pain and improved daily functioning vs control; combined oral+topical most effective. Explore (NY) PubMed 39955806 10.1016/j.explore.2025.103136 https://doi.org/10.1016/j.explore.2025.103136
Effects and comparisons of a 16-week resistance training vs. yoga intervention on psychological distress in older adults Mo, H; Li, Y 2025 RCT Linking Intervention and Impact Yes 16-week RCT comparing resistance training vs yoga vs control on psychological distress (Kessler K10) in community-dwelling older adults. Yes Yes Favorable 3-arm RCT (86 community-dwelling older adults, ~66y): both 16-week resistance training and yoga significantly reduced psychological distress (Kessler K10, ~19%) vs control, with no meaningful difference between the two. Acta Psychol (Amst) PubMed 40580915 10.1016/j.actpsy.2025.105207 https://doi.org/10.1016/j.actpsy.2025.105207
Effect of a Plant-Based Nootropic Supplement on Perceptual Decision-Making and Brain Network Interdependencies: A Randomised, Double-Blinded, and Placebo-Controlled Study O'Reilly, D; Bolam, J; Delis, I; Utley, A 2025 RCT Linking Intervention and Impact Yes Randomized double-blind placebo-controlled trial of a 60-day plant-based nootropic supplement on perceptual decision-making (visual categorization task) and EEG brain-network measures in healthy adults. No Yes Neutral Randomized, double-blind, placebo-controlled trial (healthy adults, 60-day supplementation): plant-based nootropic produced no improvement in decision accuracy or reaction time, but EEG showed increased brain-network synergy/cohesion (behavioral effect neutral). Brain Sci PubMed 40149748 10.3390/brainsci15030226 https://doi.org/10.3390/brainsci15030226
The effects of purslane consumption on blood pressure in adults: A grading of recommendations, assessment, development, and evaluation-assessed systematic review and meta-analysis of randomized controlled trials Vajdi, M; Tahvilian, N; Hassanizadeh, S; Jafari, M; Askari, G 2025 Meta Analysis Linking Intervention and Impact Yes Systematic review/dose-response meta-analysis of RCTs on purslane (Portulaca oleracea) consumption for blood pressure and anthropometric indices in adults. Yes Yes Favorable Purslane consumption significantly reduced systolic blood pressure, body weight, and BMI in adults; no significant effect on waist circumference or diastolic blood pressure. J Res Med Sci PubMed 41306619 10.4103/jrms.jrms_48_24 https://doi.org/10.4103/jrms.jrms_48_24
Effect of baduanjin exercise on salivary inflammatory and oxidative markers in the elderly with metabolic syndrome and periodontal disease: a randomized trial Ali Ismail, AM; El-Moatasem, AM; El-Moatasem, AM 2025 RCT Linking Intervention and Impact Yes RCT (50 elderly aged 65-78 with metabolic syndrome and chronic periodontal disease): 60-min Baduanjin Qigong 5x/week vs waitlist control; periodontal index and salivary inflammatory/oxidative markers. Yes No Cardiovascular Disorders Favorable RCT of 6-month Baduanjin training vs waitlist control in 50 adults aged 65-78 with metabolic syndrome and chronic periodontitis: all measured parameters except oral hygiene index improved significantly in the training group (p<0.05), with no significant change in controls. J Bodyw Mov Ther PubMed 41316618 10.1016/j.jbmt.2025.09.017 https://doi.org/10.1016/j.jbmt.2025.09.017
The relationship between Tai Chi practice, Psychological Resilience, and depression in older adults: an integrated study of mediation and network analysis Fan, F; Gou, H; Li, P; Xiang, L; Du, J 2026 Other Linking Intervention and Impact Yes Questionnaire-based cross-sectional study (mediation + network analysis) of Tai Chi practice, psychological resilience, and depression in 1,143 older adults ≥60. Yes Yes Mental Health Favorable In 1,143 older adults, Tai Chi practice was associated with lower depression, with psychological resilience mediating the relationship. Front Public Health PubMed 41859273 10.3389/fpubh.2026.1777392 https://doi.org/10.3389/fpubh.2026.1777392
Relationship between Tai Chi and the mood states, self-esteem, and subjective well-being of middle-aged and older adults: a cross-sectional study from China Li, Y; Hu, Y 2026 Other Linking Intervention and Impact Yes Cross-sectional survey of 710 adults aged 45-65 in Chongqing, China on self-reported Tai Chi exercise volume, mood, self-esteem and subjective well-being (no delivered intervention) No Yes Favorable Tai Chi exercise volume was associated with lower negative mood, higher self-esteem, and greater subjective well-being (r=-0.33 to 0.41, p<0.001), and directly predicted well-being (beta=0.47) through a chain mediation of mood and self-esteem; outcomes differed significantly by gender. Front Public Health PubMed 41684397 10.3389/fpubh.2026.1686008 https://doi.org/10.3389/fpubh.2026.1686008
An acute intervention experimental study on the effects of green and blue environment exposure combined with tai chi exercise on the emotional health of elderly males Zhang, M; Zhang, Y; Zhang, Z; Sun, H 2026 Other Linking Intervention and Impact Yes Acute single-session experiment in elderly men comparing 45 minutes of Tai Chi in conventional, green, blue, and balanced green-blue environments (Shandong, China) Yes Favorable Acute exposure to green and blue environments had positive effects on the short-term emotional health of elderly males, and combining that exposure with Tai Chi exercise further enhanced short-term emotional outcomes. Continuous exposure maintained positive emotional changes for longer during the recovery period. Front Psychol PubMed 10.3389/fpsyg.2026.1743865 https://doi.org/10.3389/fpsyg.2026.1743865
Equine-Assisted Intervention and Alzheimer's Disease: A Non-randomized, Controlled, Multicenter Study Badin, L; Bailly, N 2025 Other Linking Intervention and Impact Yes Non-randomized, controlled, multicenter study (74 older adults with Alzheimer's across 14 nursing homes): equine-assisted intervention vs adapted physical activity vs control; psychological health outcomes. Yes No Dementia Favorable Equine-assisted intervention reduced psychobehavioral disorders by week 6, improved quality of life, and slightly reduced depressive symptoms; no significant effect in the adapted-physical-activity or control groups. J Appl Gerontol PubMed 40528458 10.1177/07334648251351697 https://doi.org/10.1177/07334648251351697
Efficacy and safety of medicine-food homology Shenqi paste in older adults with diabetic sarcopenia: A randomized, double-blind, placebo-controlled trial Hua, L; Wang, Y; Yuan, X; Wang, R; Li, X; Fan, Y; Hou, Z; Yang, L; Liu, T; Sun, Q 2026 RCT Linking Intervention and Impact Yes Randomized, double-blind, placebo-controlled trial of Shenqi paste (medicine-food homology herbal formula) vs placebo, with low-intensity exercise, in older adults with diabetic sarcopenia; muscle mass, grip strength, and physical-function outcomes. Yes No Diabetes Favorable Of 90 randomized participants, the Shenqi paste group showed greater improvements than placebo control in handgrip strength, skeletal muscle index (SMI), and the five-times chair stand test (all interaction p<0.001 at T2). Secondary outcomes were assessed in 74 participants, covering frailty, nutrition, physical activity and sleep. J Ethnopharmacol PubMed 41763617 10.1016/j.jep.2026.121444 https://doi.org/10.1016/j.jep.2026.121444
The impact of balance exercise on brain age and brain morphometry: insights from MRI analysis Narula, V; Taylor, D; McLaren, R; Taylor, RL; Mahon, S; Smith, PF; Chaudhary, S; Winton, RW; Fernandez, J; Shim, V; Wang, A 2026 Other Linking Intervention and Impact Yes Cross-sectional MRI study comparing brain age and brain morphometry between regular balance-exercise practitioners (e.g., yoga, Tai Chi) and controls in healthy adults aged 55-65. No Yes Favorable Balance-exercise practitioners showed significantly more favorable brain-age and brain-morphometry measures than controls, suggesting balance exercises like yoga/Tai Chi may support healthy brain aging. Aging Clin Exp Res PubMed 41566095 10.1007/s40520-026-03322-6 https://doi.org/10.1007/s40520-026-03322-6
Beneficial Effects of Community-Based Traditional Chinese Exercises on Sleep Disturbance Among Older Adults: Systematic Review, Meta-Analysis, and Meta-Regression of Randomized Controlled Trials Lin, WT; Lee, BO; Wirojratana, V; Taplo, YM; Tonapa, SI 2025 Meta Analysis Linking Intervention and Impact Yes Systematic review, meta-analysis, and meta-regression of RCTs on community-based traditional Chinese exercises (Tai Chi, Qigong) for sleep disturbance in community-dwelling older adults. Yes Yes Favorable Community-based traditional Chinese exercises reduced sleep disturbance in community-dwelling older adults; authors support integrating them into community aging-health programs. J Transcult Nurs PubMed 41553843 10.1177/10436596251412642 https://doi.org/10.1177/10436596251412642
Perceived Benefits of an Adaptive Tai Chi Program Among Veterans with Ambulatory Limitations Simoni, Z; Walsh, D; Waite, L; Herring, B; Wilson, K; Phuong, C; Guo, Z 2025 Other Linking Intervention and Impact Yes Qualitative thematic analysis of perceived benefits of an adaptive (wheelchair-accessible) Tai Chi program among aging veterans with ambulatory limitations. Yes Yes Mental Health Favorable Veterans perceived adaptive Tai Chi to improve mindfulness, emotional regulation, and sense of control (especially for PTSD), foster social connection, and help reframe their disability. Int J Environ Res Public Health Google Scholar 41007471 10.3390/ijerph22091326 https://doi.org/10.3390/ijerph22091326
Optimal Tai Chi dose for improving anxiety, depression, and sleep quality in older adults: A Bayesian meta-analysis Chen, S; Luo, L; Yuan, Y 2025 Meta Analysis Linking Intervention and Impact Yes Bayesian dose-response meta-analysis of 37 RCTs (n=2,843 older adults) on Tai Chi for anxiety, depression, and sleep quality Yes No Mental Health Favorable Tai Chi significantly reduced anxiety (SMD −0.47) and depression (SMD −0.41) and modestly improved sleep; optimal dose 500–700 MET-min/week Clin Rehabil PubMed 40625025 10.1177/02692155251355083 https://doi.org/10.1177/02692155251355083
Effect of active mind-body movement therapies on older osteoarthritis: a systematic review and meta-analysis of randomized controlled trials Pi, C; Wang, Z; Su, L; Jian, H; Liu, J; Zhu, K; Zou, T; Mao, X; Zhang, Q; Liu, Z 2025 Meta Analysis Linking Intervention and Impact Yes Systematic review & meta-analysis of 27 RCTs (n=1,781) on active mind-body movement therapies (Tai Chi, yoga) for older adults with osteoarthritis Yes No Favorable Active mind-body movement therapies significantly reduced WOMAC pain and stiffness and improved joint function vs control; Tai Ji most effective Front Public Health PubMed 40697847 10.3389/fpubh.2025.1616053 https://doi.org/10.3389/fpubh.2025.1616053
Effects of cupping therapy on chronic musculoskeletal pain and collateral problems: a systematic review and meta-analysis Jia, Y; Dong, X; Chai, Y; Bai, Z; Sun, T; Hou, X 2025 Meta Analysis Linking Intervention and Impact Yes Systematic review/meta-analysis of RCTs assessing cupping therapy for chronic musculoskeletal pain (pain intensity, functional disability, mental health). Yes Yes Favorable Cupping therapy significantly reduced pain intensity (SMD -1.17; moderate-quality evidence); also improved functional disability. BMJ Open PubMed 40441767 10.1136/bmjopen-2024-087340 https://doi.org/10.1136/bmjopen-2024-087340
Effect of Massage and Touch on Agitation in Dementia: A Meta-Analysis Liu, X; Zang, L; Lu, Q; Zhang, Y; Meng, Q 2025 Meta Analysis Linking Intervention and Impact Yes Meta-analysis of 17 RCTs (980 patients) on massage and touch as a non-pharmacological intervention for agitation in dementia. Yes No Dementia Favorable Massage and touch significantly reduced agitation and behavioural problems; hand/head/foot massage and short-term (<=4 wks) interventions were most effective. J Clin Nurs PubMed 39902611 10.1111/jocn.17674 https://doi.org/10.1111/jocn.17674
Effects of Tai Chi Chuan on balance function in adults 60 years or older with type 2 diabetes and mild cognitive impairment in China: A secondary analysis of a multi-center randomized clinical trial Qin, J; Huang, J; Liu, J; Chen, Y; Luo, J; Tao, L; Liu, Z; Liu, W; Xu, Y; Liang, S; Chen, C; Tang, Q; Chen, Z; Chen, S; Chen, L; Tao, J 2025 RCT Linking Intervention and Impact Yes Secondary analysis of 3-arm RCT (328 adults >=60 with T2D and MCI): 24-wk supervised Tai Chi Chuan vs fitness walking vs control; balance outcomes. Yes Yes Diabetes Dementia Favorable Tai Chi Chuan improved balance measures (timed-up-and-go, single-leg stance, 5x sit-to-stand) vs fitness walking and control at 36 weeks. J Diabetes Investig PubMed 40820574 10.1111/jdi.70138 https://doi.org/10.1111/jdi.70138
The effectiveness of Tai Chi in improving depressive mood among young individuals aged 15-24 years: a systematic review and meta-analysis Huang, B; Zhou, M; Jiang, M; Song, S; Liu, L; Wang, L; Wang, L; Jian, Y; Wang, P; Yang, T; Shan, X; Liu, X 2025 Meta Analysis Linking Intervention and Impact Yes Systematic review/meta-analysis of 11 RCTs (782 participants) evaluating Tai Chi for depressive mood in young individuals aged 15-24. No Yes Mental Health Favorable Tai Chi significantly reduced depression scores in young people aged 15-24 (SMD -0.80, 95% CI -1.14 to -0.46). Front Public Health PubMed 40969649 10.3389/fpubh.2025.1517350 https://doi.org/10.3389/fpubh.2025.1517350
Effect of Tai Chi Softball on Health-Related Outcomes in Elderly Men Cheng, X; Ji, N 2025 RCT Linking Intervention and Impact Yes 12-wk RCT (140 healthy men aged 55-65): Tai Chi Softball (4-5x/wk) vs usual routine; strength, flexibility, balance, and blood-lipid outcomes. No Yes Favorable Tai Chi Softball significantly improved handgrip strength, flexibility, single-leg stance, vital capacity, blood pressure, and lipid profile (TC, TG, LDL-C) vs control. Am J Mens Health PubMed 40304406 10.1177/15579883251332745 https://doi.org/10.1177/15579883251332745
Effects of Tai Chi Chuan on cognitive function in adults 60 years or older with mild cognitive impairment: a systematic review and meta-analysis Wang, WT; Wang, H 2025 Meta Analysis Linking Intervention and Impact Yes Systematic review/meta-analysis of RCTs on stand-alone Tai Chi Chuan for global cognition, memory, and executive function in adults ≥60 with mild cognitive impairment. Yes Yes Dementia Favorable Meta-analysis of 9 RCTs (1,066 adults ≥60, mean age 74): long-term Tai Chi Chuan significantly improved global cognition (SMD 0.488) plus memory and executive function. Front Physiol PubMed 40236822 10.3389/fphys.2025.1556622 https://doi.org/10.3389/fphys.2025.1556622
The effect of traditional Chinese exercises on low Back pain and disability in middle-aged and older adults: A systematic review Qi, Y; Zhuang, M; Liang, R; Shaharudin, S 2025 Meta Analysis Linking Intervention and Impact Yes Systematic review/meta-analysis of RCTs on traditional Chinese exercises (Tai Chi, Qigong, etc.) for pain and disability in middle-aged/older adults with low back pain. Yes Yes Favorable Meta-analysis of 11 RCTs: traditional Chinese exercises reduced low-back pain (VAS MD −1.38) and disability (ODI MD −4.36) vs control; evidence rated low quality (GRADE). Prev Med Rep PubMed 40290641 10.1016/j.pmedr.2025.103072 https://doi.org/10.1016/j.pmedr.2025.103072
Physical and Mental Benefits of Chair Yoga for Older Adults: A Case Series Smith, J; Buessing, A; Pierce, C; Hybarger, P; Antonowich, T; Akins, W; Smith, B 2025 Case Study Linking Intervention and Impact Yes 8-week once-weekly chair yoga program (breathwork, movements, cool-down) in 4 independent-living older adults; balance (Tinetti) and quality-of-life (SF-36) outcomes. Yes No Favorable Case series (4 adults aged 77–92): 8-week chair yoga improved Tinetti balance/gait for all and SF-36 subscales for most; feasible with potential functional-mobility benefits. Int J Exerc Sci PubMed 41210924 10.70252/COQS7170 https://doi.org/10.70252/COQS7170
Investigating the effect of laughter yoga on happiness and life expectancy in an elderly population Seraj, Z; Sanagoo, A; Behnampour, N; Jouybari, L 2025 RCT Linking Intervention and Impact Yes Eight 45-minute laughter yoga sessions vs control in 220 community-dwelling elderly (Iran); happiness (Oxford) and hope/life-expectancy (Snyder) outcomes. Yes Yes Favorable RCT (220 elderly): eight 45-min laughter yoga sessions significantly increased happiness and hope/life expectancy vs control (p<0.001). J Educ Health Promot PubMed 40979358 10.4103/jehp.jehp_482_24 https://doi.org/10.4103/jehp.jehp_482_24
Effect of traditional Chinese fitness exercises on bone mineral density of middle-aged and elderly people-A systematic review and network meta-analysis Ren, Z; He, L; Li, X; Yan, L; Ren, Z; Liu, X 2025 Meta Analysis Linking Intervention and Impact Yes Systematic review/network meta-analysis of RCTs comparing traditional Chinese fitness exercises (Taiji, Baduanjin, Wuqinxi, etc.) for bone mineral density in middle-aged and elderly people. Yes Yes Favorable Network meta-analysis of RCTs: traditional Chinese fitness exercises may safely improve bone mineral density in middle-aged/elderly; no significant differences among most types (SUCRA rankings provided). Complement Ther Clin Pract PubMed 39908682 10.1016/j.ctcp.2025.101956 https://doi.org/10.1016/j.ctcp.2025.101956
Effects of six traditional Chinese mind-body exercises on obesity and cardiovascular risk factors in middle-aged and elderly hypertensive patients: a network Meta-Analysis of 49 RCTs Li, H; Lin, X; Wu, X; Huang, R 2025 Meta Analysis Linking Intervention and Impact Yes Network meta-analysis of 49 RCTs assessing six traditional Chinese mind-body exercises (Tai Chi, Baduanjin, Liuzijue, Qigong, etc.) on obesity and cardiovascular risk factors in hypertensive patients ≥45 years. Yes Yes Cardiovascular Disorders Favorable Network meta-analysis of 49 RCTs (hypertensive adults ≥45): traditional Chinese mind-body exercises improved obesity and cardiovascular risk factors, with rankings identifying the most effective modalities. BMC Cardiovasc Disord PubMed 40826319 10.1186/s12872-025-05084-x https://doi.org/10.1186/s12872-025-05084-x
The effectiveness of exercise interventions on muscle strength and balance function in pre-frail older adults: a systematic review and Bayesian network meta-analysis Ma, N; Lu, Z; Mei, X; Ma, L; Zhang, Q 2026 Meta Analysis Linking Intervention and Impact Yes Systematic review/Bayesian network meta-analysis of 17 RCTs comparing 10 exercise interventions on grip strength, SPPB, and Timed Up-and-Go in pre-frail adults ≥60. Yes Yes Favorable Exercise interventions improved muscle strength and balance; elastic band exercise and progressive exercise + Tai-chi snacking ranked most effective (no significant differences in TUG time). Front Public Health PubMed 41675088 10.3389/fpubh.2025.1718120 https://doi.org/10.3389/fpubh.2025.1718120
Effect of Yoga Practices on Postural Stability, Fall Risk, and Psychological Wellbeing in Older Adults Shete, S; Verma, A; Bhogal, RS; Tiwari, S 2026 Other Linking Intervention and Impact Yes 12-week yoga program (postures, breathing, meditation) vs waitlist control in older adults aged 65-85; balance, fear of falling, mobility, anxiety, and depression outcomes. Yes No Favorable Quasi-experimental study (50 analyzed, ages 65-85): yoga significantly improved balance and functional mobility and reduced fear of falling, anxiety, and depression vs waitlist control (which deteriorated). Geriatrics (Basel) PubMed 41718364 10.3390/geriatrics11010016 https://doi.org/10.3390/geriatrics11010016
Yoga as a form of leisure-time physical activity and pregnancy health outcomes Thrower, A; Modlin, S; Whitaker, KM; Gibbs, BB 2026 Prosp Cohort Study Linking Intervention and Impact Yes Prospective cohort (nuMoM2b) of nulliparous pregnant women assessing whether leisure-time yoga is associated with lower risk of adverse pregnancy outcomes. No Yes Favorable Cohort of 7,502 nulliparous women: yoga was associated with fewer adverse pregnancy outcomes (RR 0.86 some yoga, 0.78 high yoga), lower preterm birth with high yoga (RR 0.42), and less inadequate or excessive gestational weight gain; no association with other outcomes. BMC Pregnancy Childbirth PubMed 41652364 10.1186/s12884-026-08659-4 https://doi.org/10.1186/s12884-026-08659-4
Effect of yoga versus light exercise and its impact on quality of life among elderly - A systematic review and meta-analysis Subalakshmi, S; Mahendran, R; Arthi, D; Saranya, S; Mohan, R; Mary, JF 2025 Meta Analysis Linking Intervention and Impact Yes Systematic review/meta-analysis comparing yoga vs light exercise on health-related quality of life and mental wellbeing in people aged 60+. Yes Yes Favorable Yoga significantly improved quality-of-life dimensions (including cognitive function and sleep) and reduced anxiety, depression, and stress, with greater cognitive benefit than light exercise. J Family Med Prim Care PubMed 41089999 10.4103/jfmpc.jfmpc_2005_24 https://doi.org/10.4103/jfmpc.jfmpc_2005_24
The impact of Tai Chi on emotional regulation efficacy and subjective wellbeing in the elderly and the mediating mechanism Wang, S; Huang, Y; Si, X; Zhang, H; Zhai, M; Fan, H; Ding, L 2025 RCT Linking Intervention and Impact Yes 8-week 24-form simplified Tai Chi (five 30-minute sessions weekly) vs usual lifestyle in 60 healthy older adults in Zhengzhou, China Yes Favorable Tai Chi practice significantly improved emotional regulation efficacy (d=1.29), positive and negative affect, and subjective wellbeing; emotional regulation efficacy mediated the effect on wellbeing. Front Psychol PubMed 10.3389/fpsyg.2025.1550174 https://doi.org/10.3389/fpsyg.2025.1550174
Effects of different physical activity interventions on executive function in older adults with dementia: a systematic review and network meta-analysis Zhu, Y; Li, S; Xiao, Z; Wang, H; Zhang, X; Huang, Q; Yin, R; Guo, K; Li, D 2025 Meta Analysis Linking Intervention and Impact Yes Systematic review/network meta-analysis of 24 RCTs ranking physical-activity interventions (resistance, mind-body, aerobic) for executive function in older adults with dementia. Yes No Dementia Favorable Resistance exercise ranked most effective for executive function (SUCRA 89.2%), followed by mind-body exercise (71.4%) and aerobic exercise (60.0%). Front Neurol PubMed 41127293 10.3389/fneur.2025.1643957 https://doi.org/10.3389/fneur.2025.1643957
The effect of laughter yoga and music intervention on depression, anxiety, and stress in the Rafsanjan-Iran aged: a randomized clinical trial study Tabei, M; Ravari, A; Kataria, M; Mirzaei, T; Kamiab, Z 2025 RCT Linking Intervention and Impact Yes 3-arm RCT comparing laughter yoga vs music intervention vs control on depression, anxiety, and stress in 91 depressed older adults aged 60-75. Yes Yes Mental Health Favorable Both laughter yoga and music reduced depression, anxiety, and stress; laughter yoga showed a superior effect and better acceptance among elders. Aging Ment Health PubMed 39107930 10.1080/13607863.2024.2385454 https://doi.org/10.1080/13607863.2024.2385454
Mpox among people reporting being unhoused or engaging in transactional sex within a multijurisdictional case-control study of sexually and gender minoritized individuals- United States, August 2022-March 2024 Sherman, JP; Morris, AL; Niccolai, LM; Ruff, A; Schneider, D; Sutton, M; Hawkins, S; Pathela, P; Betancourt, GS; Rothrock, G; Nadle, J; Rowlands, JV; Felsen, CB; Britton, A; Farley, MM; Duval, LM; Kamis, KF; Still, WL; Morrow, AS; Waddell, CJ 2025 Other Linking Gap and Impact Yes N/A Yes Favorable Experiencing homelessness (aOR 2.4, 95% CI 1.35–4.36) and engaging in transactional sex (aOR 2.4, 95% CI 1.35–4.31) were each associated with higher odds of mpox, and the interaction term was not significant. Among participants, 63 (4.9%) were unhoused, 61 (4.7%) engaged in transactional sex and 20 (1.5%) reported both. The authors called for tailored vaccine outreach, housing support and low-barrier care. Social Science & Medicine PubMed 10.1016/j.socscimed.2025.118497 https://www.sciencedirect.com/science/article/abs/pii/S0277953625008287
Subsidized Housing Availability and Preventive Care Utilization in US Neighborhoods. Wiese, D; Ashad-Bishop, K; Jemal, A; Islami, F 2025 Other Linking Intervention and Impact Yes N/A Favorable Outcomes assessed were tract-level prevalence of breast, cervical, colorectal and cholesterol screening in relation to subsidized housing availability. Across 70,006 tracts, adjusted cervical and cholesterol screening increased monotonically across quintiles of subsidized housing in extreme-poverty areas; cervical screening was 5.47 percentage points higher (95% CI = 5.20-5.73) in Q5 (81.3%) than Q1 (75.8%), with cholesterol screening differences similar in magnitude. Differences in breast and colorectal screening across quintiles were minimal (<1%) within poverty strata. Journal of General Internal Medicine PubMed 10.1007/s11606-025-09644-x https://link.springer.com/article/10.1007/s11606-025-09644-x
Where your liver lives matters: How neighborhoods shape transplant outcomes Thompson, V; Strauss, A 2025 Other Linking Gap and Impact Yes N/A End-Stage Liver Disease Favorable The authors argued that neighborhood-level disadvantage stems from structural forces such as systemic racism operating through zoning, housing access and neighborhood segregation, and that place-based deprivation indices allow these mechanisms to be examined in relation to post-transplant outcomes. They offered illustrative examples of how SDI components could influence liver transplant recipient outcomes and urged researchers to select indices deliberately and build robust frameworks. The underlying mortality and graft survival results are attributed to Forman et al. Liver Transplantation Google Scholar 10.1097/LVT.0000000000000510 https://www.ovid.com/jnls/lt/fulltext/10.1097/lvt.0000000000000510~where-your-liver-lives-matters-how-neighborhoods-shape
Delayed Management of Pyoderma Gangrenosum in an Unhoused Patient: The Role of Social Determinants in Disease Severity Ambati, P; Sattaur, A 2025 Case Study Linking Gap and Impact No N/A Yes Autoimmune Disease Mental Health Favorable Barriers to outpatient care, medication access and hygiene maintenance contributed directly to disease severity. The patient presented with full-thickness ulcers with hypergranulated tissue and maceration; before diagnosis, repeated visits and referrals cost him his job and financial support. Psychosocial history included complex trauma, depression and functional decline, with distress from chronic pain, stigmatization and repeated dismissal by the health system. He was discharged to a wound care referral with a poor prognosis given advanced disease and limited access to care. The authors called for interdisciplinary models integrating dermatologic care with housing support and case management. Journal of Investigative Dermatology (meeting abstract) Google Scholar 10.1016/j.jid.2025.09.383 https://www.jidonline.org/article/S0022-202X(25)03529-8/fulltext
Impact of social determinants of health on mortality in diffuse large B-cell lymphoma (DLBCL) using real-world data. Canavan, M; Wang, M; Mbah, O; Kaur, M; Hall, M; Khan, A; McDermott, JD; Schmitter, M; Afghahi, A; Goyal, G 2025 Other Linking Gap and Impact No N/A Yes Hematologic Disorders Favorable Patients living in the most socially deprived areas had a significantly higher risk of death, after adjustment for clinical and demographic factors. Journal of Clinical Oncology (ASCO meeting abstract) Google Scholar 10.1200/JCO.2025.43.16_suppl.11097 https://ascopubs.org/doi/10.1200/JCO.2025.43.16_suppl.11097
Supportive housing program and influenza vaccination rates among veterans experiencing homelessness Graham, LA; Decker, HC; Tsai, J 2026 Other Linking Intervention and Impact Yes Veterans experiencing homelessness received HUD-VASH: Housing Choice Vouchers plus VHA case management and supportive services, compared with homeless veterans in VHA care not enrolled in HUD-VASH. Yes Favorable Recent HUD-VASH enrollment was associated with 48% higher odds of influenza vaccination in the adjusted difference-in-differences model (OR 1.48, 95% CI 1.19–1.85, p < .001). Vaccination during the 3-month follow-up reached 32.1% among HUD-VASH enrollees versus 20.8% among other homeless veterans (standardized mean difference 0.258, 95% CI 0.249–0.266, p < .001), across 497,892 veterans experiencing homelessness of whom 61,018 (12.3%) enrolled. Vaccination was also more common among older veterans (mean 58 vs 52 years) and those with greater comorbidity burden. JAMA Netw Open Siren 41733916 10.1001/jamanetworkopen.2026.0001 https://pubmed.ncbi.nlm.nih.gov/41733916/
Health care outcomes of homelessness prevention programs in veterans experiencing housing instability Nelson, RE; Chapman, AB; Montgomery, AE; Suo, Y; Effiong, A; Shorter, C; Greene, T; Tsai, J; Gelberg, L; Kertesz, SG; Byrne, T 2026 Other Linking Intervention and Impact Yes Veterans experiencing housing instability received VA Supportive Services for Veteran Families: short-term housing-related financial assistance and supportive services. Yes Favorable SSVF enrollment was associated with lower 3-year all-cause mortality (HR 0.87, 95% CI 0.82–0.92), higher outpatient costs (+$7,534) and lower inpatient costs (−$10,020). JAMA Health Forum Siren 41575762 10.1001/jamahealthforum.2025.6417 https://pubmed.ncbi.nlm.nih.gov/41575762/
Health and economic impacts of stable housing provision for older adults Gande, V; Goldhaber-Fiebert, JD; Brandeau, ML 2026 Other Linking Intervention and Impact Yes Adults experiencing homelessness were provided stable housing with no requirement to enter treatment, modelled in simulated cohorts of 1,000 adults aged 55 and over versus 18–54. Yes Yes Alcohol/Drug Dependence Favorable In the 55+ cohort, stable housing reduced 5-year deaths from 218 to 184 and raised lifetime QALYs from 5.64 to 7.52, at $80,700 per QALY gained ($54,800 in the 18-54 cohort). Cost per QALY stayed under $100,000 in sensitivity analyses. JAMA Health Forum Siren 41961493 10.1001/jamahealthforum.2025.6417 https://pubmed.ncbi.nlm.nih.gov/41961493/
Impact of housing support services for Medicaid enrollees with serious mental illness, substance use disorder Bruefach, T; Mkuu, RS; Hall, JM; Rivero-Mendoza, D; Lurk, PA; Vincent, C; McCraney, MR; Chakrabarti, C; Erichsen, K; Cogle, CR 2026 Other Linking Intervention and Impact Yes Medicaid enrollees received housing assistance under Florida's Statewide Medicaid Managed Care Section 1115 waiver pilot, comprising transitional housing support, tenancy support, peer support and crisis management. Yes Mental Health Alcohol/Drug Dependence Neutral Results were mixed by service type. Tenancy support was associated with 51% lower odds of all-cause mortality and peer support with 20% lower emergency department use, but transitional housing support was associated with 15% more ED visits, and crisis management with 45% more ED visits, 41% more outpatient visits and 90% more psychiatric hospitalizations. Health Aff (Millwood) Siren 41494122 10.1377/hlthaff.2025.00581 https://pubmed.ncbi.nlm.nih.gov/41494122/
Federal housing assistance and stage at cancer diagnosis among older adults in the US Pollack, CE; Blackford, AL; Craig, TK; Fan, Q; Hussaini, SM; Chen, KL; Polsky, D; Katana Ogongo, M; Warren, JL; Gross, CP; Yabroff, KR 2025 Other Linking Intervention and Impact Yes Older adults received federal housing assistance (Housing Choice vouchers, multifamily housing or public housing) which caps household spending on rent and utilities. Yes Cancer Favorable Housing assistance was associated with lower odds of distant-stage diagnosis versus matched controls for breast cancer (aOR 0.85), colorectal cancer (aOR 0.90) and non-small cell lung cancer (aOR 0.83) among 52,532 assisted adults aged 66–95. No significant association was found for prostate cancer. JAMA Netw Open Siren 41060653 10.1001/jamanetworkopen.2025.36281 https://pubmed.ncbi.nlm.nih.gov/41060653/
Is gaining housing associated with higher rates of cancer screening among US veterans experiencing homelessness? Decker, H; Graham, L; Titan, A; Kanzaria, H; Hawn, M; Wick, E; Tsai, J; Kushel, M 2025 Other Linking Intervention and Impact Yes N/A Yes Cancer Favorable Veterans who gained housing were more than twice as likely to undergo colorectal cancer screening as those who remained homeless (aHR 2.3, 95% CI 2.2–2.3). Of 117,619 veterans eligible for but not up to date on colorectal cancer screening, 49.0% gained housing; of 6,517 eligible for breast cancer screening, 47.5% gained housing. Ann Fam Med Siren 40721329 10.1370/afm.240520 https://pubmed.ncbi.nlm.nih.gov/40721329/
Multimorbidity of mental health and substance use disorders among housed and homeless U.S. veterans Tsai, J; Szymkowiak, D; Beydoun, H 2025 Other Linking Gap and Impact Yes N/A Yes Mental Health Alcohol/Drug Dependence Favorable Comorbid mental health/substance use disorder rates were 24.7% among homeless veterans and 32.0% among those in supported housing, vs 5.8% among independently housed veterans. Homeless veterans with comorbidity used more outpatient, inpatient and ED care than supported-housing veterans, who in turn used more than independently housed veterans. Sci Rep Siren 40307423 10.1038/s41598-025-99394-x https://pubmed.ncbi.nlm.nih.gov/40307423/
Association between use of services to address adverse social determinants of health and documented suicide attempt among patients in the Veterans Health Administration Blosnich, JR; DeRussy, A; Richman, JS; Dichter, ME; True, G; Montgomery, AE 2025 Other Linking Intervention and Impact Yes Veterans with housing instability, justice involvement or unemployment received VA social services including housing, justice and employment programs at none, low or high levels of intensity. Yes Mental Health Neutral High receipt of housing services was associated with higher odds of a documented suicide attempt in the following 6 months (aOR 1.14, 95% CI 1.06–1.22), as was high use of justice programs (aOR 1.24). No significant association was found for employment services. The authors interpreted the positive association as increased surveillance and documentation rather than increased risk. J Community Health Siren 40167958 10.1007/s10900-025-01467-5 https://pubmed.ncbi.nlm.nih.gov/40167958/
Youth experiencing homelessness at risk for suicide: Psychosocial risk factors and service use patterns Chavez, LJ; Kelleher, KJ; Bunger, A; Feng, X; Fitzpatrick, M; Ford, JL; Mallory, AB; Sheftall, AH; Yilmazer, T; Pizzulo, A; Hawke, JL; Davenport, MA; Slesnick, N 2025 Other Linking Gap and Impact Yes N/A Yes Mental Health Alcohol/Drug Dependence Favorable Substantial unmet need was identified: only 40% of youth received medical care and 34% mental health services in the prior 3 months, and just 15% received mental or emotional health services (34% in the high-risk group). Among the 193 youth, 16.6% were moderate-risk and 18.1% high-risk for suicide, and 57.5% reported ever being diagnosed with a psychiatric disorder. BMC Public Health Siren 39905400 10.1186/s12889-024-21212-2 https://pubmed.ncbi.nlm.nih.gov/39905400/
Yoga or Strengthening Exercise for Knee Osteoarthritis: A Randomized Clinical Trial Abafita, BJ; Singh, A; Aitken, D; Ding, C; Moonaz, S; Palmer, AJ; Blizzard, L; Inglis, A; Drummen, SJJ; Jones, G; Bennell, KL; Antony, B 2025 RCT Linking Intervention and Impact Yes 12-week structured yoga vs strengthening exercise program in adults (≥40y) with knee osteoarthritis Yes Yes Neutral Both groups improved knee pain over 12 weeks with no significant between-group difference; yoga was noninferior to strengthening and showed modest gains in symptoms, quality of life, and depression JAMA Netw Open PubMed 40198073 10.1001/jamanetworkopen.2025.3698 https://doi.org/10.1001/jamanetworkopen.2025.3698
Combined mind-body physical exercise, cognitive training, and nurse-led risk factor modification to enhance cognition among older adults with mild cognitive impairment in primary care: a three-arm randomised controlled trial Xu, Z; Zhang, D; Yip, BH; Lee, EK; Poon, PK; Peters, R; Yang, Z; Lee, AT; Leung, MK; Wong, EL; Mok, VC; Lam, LC; Wong, SY 2025 RCT Linking Intervention and Impact Yes 15-month three-arm RCT: combined cognitive training + mind-body exercise + nurse-led risk-factor modification (CPR) vs nurse-led RFM vs health advice in older adults (60–80y) with MCI Yes Yes Dementia Favorable At 15 months neither CPR nor RFM significantly improved cognition (ADAS-Cog) over health advice; authors conclude such interventions need further refinement before being recommended Lancet Healthy Longev PubMed 40294622 10.1016/j.lanhl.2025.100706 https://doi.org/10.1016/j.lanhl.2025.100706
Effect of Tai Chi on Bone Mineral Density in Middle-Aged and Older Adults: A Meta-Analysis Cui, J; Qian, C; Liu, Y 2025 Meta Analysis Linking Intervention and Impact Yes Meta-analysis of 17 RCTs (n=1,253) on Tai Chi and bone mineral density in middle-aged and older adults Yes Yes Favorable Significant BMD improvements at lumbar spine, greater trochanter, Ward's triangle, femoral neck, and calcaneus; effects greater with ≥6 months of training Orthop Rev (Pavia) PubMed 40688454 10.52965/001c.142059 https://doi.org/10.52965/001c.142059
Association between yoga and multimorbidity: a nationwide study of 279,885 middle-aged and older adults Wang, K; Wang, P; Li, Y; Wang, C; Veldheer, S; Wang, F; Na, M; Sun, L; Gao, X 2025 Other Linking Intervention and Impact Yes Cross-sectional analysis of BRFSS surveys (2015/17/19; n=279,885 adults ≥45) comparing yoga practitioners, other exercisers, and non-exercisers Yes Yes Favorable Yoga associated with lower odds of multimorbidity and individual chronic conditions in a dose-response manner BMC Public Health PubMed 40050815 10.1186/s12889-025-22035-5 https://doi.org/10.1186/s12889-025-22035-5
Effect of Yoga Therapy on Hypothyroidism: A Systematic Review Bhandari, RB; Mahto, PK 2024 Systematic Review Linking Intervention and Impact Yes PRISMA systematic review of 8 studies (n=421) with 3–6 month yoga interventions in hypothyroidism patients Yes Yes Favorable Yoga showed positive effects as an adjunct therapy on thyroid markers and comorbid conditions; evidence limited by small samples Ann Neurosci PubMed 39544669 10.1177/09727531241282516 https://doi.org/10.1177/09727531241282516
A meta-analysis of behaviour change techniques in social interventions targeting improved cognitive function in older adults Siette, J; Chong, V; Samtani, S; Harris, C; Steiner-Lim, G; MacMillan, F 2025 Meta Analysis Linking Intervention and Impact Yes Participants received social-based behavioural interventions including group chat, arts activities and reminiscence, across 15 pooled RCTs (N = 1,785). Yes No Dementia Neutral Social-based behavioural interventions produced a medium effect on global cognition (d = 0.80) but no effect on executive function, across 15 RCTs (N = 1,785). BMC Public Health PubMed 40148812 10.1186/s12889-025-22229-x https://doi.org/10.1186/s12889-025-22229-x
Exploring the impact of community-based interventions on healthy older adults' physical health, psychological wellbeing, and social connections: A systematic review Elhag, S; Niechcial, M; Potter, L; Gow, A 2025 Systematic Review Linking Intervention and Impact Yes Older adults received community-based interventions comprising physical, mental and social activities aimed at supporting healthy ageing, across 56 pooled studies. Yes No Favorable Most community-based interventions produced positive results across 56 studies, reducing depression and anxiety and improving functioning, sleep and social participation. Ageing Res Rev PubMed 40480291 10.1016/j.arr.2025.102784 https://doi.org/10.1016/j.arr.2025.102784
Effect of specific and sensitive interventions for the social protection of people affected by tuberculosis: a meta-analysis Ferreira, M; Gil, J; de Paula Andrade, R; de Almeida Soares, D; Monroe, A; Fronteira, I 2025 Meta Analysis Linking Intervention and Impact Yes TB-affected people received social protection interventions, either TB-specific (disease-targeted cash, food or transport support) or TB-sensitive (general social assistance), across 13 pooled studies. Yes Yes Chronic Lung Disorders Favorable Social protection interventions had a positive effect on tuberculosis treatment success across 13 articles and 82,602 participants, with TB-specific interventions showing OR 2.16 and TB-sensitive interventions OR 1.15. Arch Public Health PubMed 41084064 10.1186/s13690-025-01659-4 https://doi.org/10.1186/s13690-025-01659-4
Better Together?: A Systematic Review of the Effectiveness of HIV Prevention Interventions that Build or Strengthen Social Ties Fonner, V; Yeh, P; Kennedy, C; O'Reilly, K; Sweat, M 2025 Systematic Review Linking Intervention and Impact Yes Participants in low- and middle-income countries received HIV-prevention interventions designed to build or strengthen social ties, across 28 pooled studies reported in 51 articles. Yes Yes HIV / AIDS Favorable Most of the 28 included studies (51 articles) showed positive changes, including reduced HIV incidence and increased condom use and health service use. AIDS Behav PubMed 40369304 10.1007/s10461-025-04745-4 https://doi.org/10.1007/s10461-025-04745-4
Treatment adherence, social support and coping mechanisms among patients with drug-sensitive tuberculosis: a cross-sectional study in two directly-observed therapy centres in southwest Nigeria Adisa, R; Durojaye, D 2025 Other Linking Intervention and Impact Yes N/A Yes Yes Chronic Lung Disorders Neutral The study examined treatment adherence, social support and coping mechanisms among drug-sensitive tuberculosis patients attending two DOT centres in southwest Nigeria. BMJ Open PubMed 41093333 10.1136/bmjopen-2025-099559 https://doi.org/10.1136/bmjopen-2025-099559
Artificial intelligence chatbots as a source of virtual social support: Implications for loneliness and anxiety management Merrill, KJ; Mikkilineni, S; Dehnert, M 2025 Other Linking Intervention and Impact Yes Participants received AI chatbot social-support messages varying in person-centeredness and context, in a 2×2 experimental design. Yes Mental Health Favorable Highly person-centered AI messages increased emotional validation, an effect mediated by social-support quality and perceived interpersonal warmth. Ann N Y Acad Sci PubMed 40572032 10.1111/nyas.15400 https://doi.org/10.1111/nyas.15400
Social Support's Dual Mechanisms in the Loneliness-Frailty Link Among Older Adults with Diabetes in Beijing: A Cross-Sectional Study of Mediation and Moderation Cai, H; Liang, H; Zhu, J; Shi, L; Li, J; Lin, Y 2025 Other Linking Intervention and Impact Yes N/A Yes Yes Diabetes Favorable Loneliness was correlated with frailty among 442 Beijing adults aged 60 and over with type 2 diabetes, of whom 55.2% were frail. Social support partially mediated the association (30.86%) and also moderated it. Healthcare (Basel) PubMed 40724738 10.3390/healthcare13141713 https://doi.org/10.3390/healthcare13141713
The impact of a student-led intergenerational support program on life satisfaction, loneliness, and psychological well-being of institutionalized older adults Mostafa, N; Harfoush, M; Atta, M; Fouad, R; El Garhy, S 2025 Other Linking Intervention and Impact Yes Institutionalized older adults received a student-led intergenerational support program; 37 were assigned to the program and 37 to a control group. Yes No Favorable The program increased life satisfaction and reduced loneliness, depression and anxiety among 74 institutionalized older adults. Geriatr Nurs PubMed 39904066 10.1016/j.gerinurse.2025.01.018 https://doi.org/10.1016/j.gerinurse.2025.01.018
Pet Ownership, Depression, Anxiety, Well-Being, and Cognitive Functioning in Older Adults: Cross-Sectional Study Saraiva de Albuquerque, N; Schmitz Klain, I; Sigaran Machado, L; de Lara Machado, W; Moret-Tatay, C; Quarti Irigaray, T 2026 Other Linking Intervention and Impact Yes N/A Yes Yes Neutral Depression, anxiety, well-being and cognitive functioning were compared between pet owners and non-owners among 215 community-dwelling older adults aged 59 and over, 53% of whom owned pets. JMIR Form Res PubMed 41627868 10.2196/76289 https://doi.org/10.2196/76289
Exploring the Role of Cognitive Reserve and Human-Animal Interaction in Late-Life Depression: A Moderation Analysis de Albuquerque, N; Sessegolo, N; Moret-Tatay, C; Irigaray, T 2025 Other Linking Intervention and Impact Yes N/A Yes Yes Favorable Higher cognitive reserve was associated with lower depressive symptoms among 215 older adults aged 59 and over, an association moderated by pet ownership and significant only among pet owners. Geriatrics (Basel) PubMed 40700284 10.3390/geriatrics10040089 https://doi.org/10.3390/geriatrics10040089
A smart secure virtual reality immersive application for alzheimer's and dementia patients Al-Rajab, M; Lu, J; Amawi, S; Elmehalawy, N; Babillie, B; Alasmi, Y; Ibrahim, H; Ellahham, S; Sawsaa, A; Al Zraiqat, S 2025 Other Linking Intervention and Impact Yes Patients with Alzheimer's disease or dementia used an immersive VR platform combining ChatGPT and voice recognition, offering cognitive stimulation, companionship, memory games and virtual trips. Yes No Dementia Favorable Patients, families and clinicians reported greater interest, better quality of life, less isolation and improved cognitive functioning following initial evaluation of the VR-AI platform. Development and initial evaluation only; no controlled comparison. Sci Rep PubMed 40835985 10.1038/s41598-025-14624-6 https://doi.org/10.1038/s41598-025-14624-6
Ai-Aun Chatbot: A Pilot Study on the Effectiveness of an Artificial Intelligence Intervention for Mental Health Among Thai Older Adults Imkome, E; Soonthornchaiya, R; Lakanavisid, P; Deepaisarn, S; Wongpatikasereeb, K; Suebnukarn, S; Matthews, A 2025 RCT Linking Intervention and Impact Yes Thai older adults used the Ai-Aun AI avatar chatbot on an Android phone for 15 days; 22 were randomized to the chatbot and 22 to a control group. Yes No Favorable The chatbot group had significantly better mental-health scores than controls (p < 0.001, η² = 0.27) among 44 randomized Thai older adults, and 81.8% reported the app was easy to use. Nurs Health Sci PubMed 40189210 10.1111/nhs.70093 https://doi.org/10.1111/nhs.70093
Effect of Virtual Zen Garden on Quality of Life of Residents in Long-Term Care Home Yuen, I; Kwok, T 2025 Other Linking Intervention and Impact Yes Long-term care residents in Hong Kong took part in Virtual Zen Garden sessions delivered through virtual reality. Yes No Favorable The Virtual Zen Garden showed positive effects on quality of life across physical, psychological, social and environmental domains, with nine theme clusters identified from interviews with 24 long-term care residents. Int J Environ Res Public Health PubMed 40283736 10.3390/ijerph22040510 https://doi.org/10.3390/ijerph22040510
The Role of Psychosocial Support in Balance Improvements Following a Community-Based Tai Chi Program Among Latino Older Adults Qin, Z; Rajaram, SS; Padilla, C; Siu, KC 2026 Other Linking Intervention and Impact Yes Latino older adults at risk of falling completed a 12-week community-based Tai Chi program; balance was assessed with the Timed Up and Go Test at baseline, immediately post-intervention, and at 12-week follow-up. Yes No Favorable Participants with higher levels of psychosocial support showed significantly greater improvement in balance than those with lower support scores (p < 0.05) immediately after the 12-week Tai Chi program, but these improvements were not maintained at follow-up, among 23 Latino older adults with complete outcome data. Findings should be interpreted cautiously given the single-group design without a control group. Behavioral Sciences (Basel), Vol. 16, Issue 4, Article 573 Google Scholar 42073936 10.3390/bs16040573 https://doi.org/10.3390/bs16040573
The association between social determinants of health and cancer screening: Cross-sectional survey results from the National Health Interview Survey Fox, C; Milton, A; Jordan, L; Anderson, J; LoConte, N; Narayan, A 2025 Other Linking Gap and Impact No N/A Yes Yes Cancer Favorable Food insecurity, lack of internet access, trouble with housing costs, lack of health insurance and transportation difficulties were each associated with significantly lower mammography rates (p < 0.01) in both unadjusted and adjusted analyses, among 8,392 weighted eligible female respondents of whom 74.6% reported mammography within two years; employment status was not associated (p > 0.10). For colorectal screening (14,765 weighted eligible respondents, 69.0% screened), all seven domains showed significantly lower screening unadjusted (p < 0.001); after adjustment only internet access, lack of health insurance, lack of college education and employment status remained significant (all p < 0.001), while food insecurity (p = 0.224), housing costs (p = 0.628) and transportation delays (p = 0.090) did not. The authors concluded that lack of internet access, health insurance and formal education were independently associated with lower screening and called for targeted SDOH interventions. Cancer Epidemiology, Biomarkers & Prevention (meeting abstract) PubMed 10.1158/1538-7755.DISP25-C144 https://doi.org/10.1158/1538-7755.DISP25-C144
Public health policies and interventions to address health inequities in high-income countries: an umbrella review Hayre, J; Canning, E; Pearce, H; Khera, R; Ford, J 2026 Systematic Review Linking Intervention and Impact Yes Included reviews evaluated macro-level public health policies and population-level interventions in OECD countries, classified by agentic demand and population reach on a Health Equity Pyramid. Favorable Interventions with low agentic demand, such as welfare reform, housing support, and legislative measures, yielded the most consistent reductions in health inequity. High-agentic interventions were effective only when carefully tailored to disadvantaged populations and otherwise risked widening disparities. BMC Public Health PubMed 41645123 10.1186/s12889-025-25876-2 https://link.springer.com/article/10.1186/s12889-025-25876-2
Rental assistance, housing insecurity, & well-being: Spillover effects of emergency rental assistance during the COVID-19 pandemic Fusaro, VA; Baidoo, C; Carey, N; Coley, RL 2026 Other Linking Intervention and Impact Yes Vulnerable renter households who received federal Emergency Rental Assistance Program aid (approximately $47 billion), compared with applicants still awaiting a decision. Yes Favorable Outcomes assessed were non-housing spillover effects of rental assistance: food insufficiency and psychological distress. Rental assistance reduced the probability of food insufficiency (average treatment effect -0.09), anxiety symptoms (-0.10), and depression symptoms (-0.08). Social Science & Medicine PubMed 10.1016/j.socscimed.2025.118795 https://www.sciencedirect.com/science/article/abs/pii/S0277953625011268
Broadband internet access as a social determinant of health in the early COVID-19 pandemic in U.S. counties Allen, S 2025 Other Linking Gap and Impact Yes N/A Favorable Higher county broadband internet access was associated with lower COVID-19 mortality, with a negative, strong association robust across all three periods tested, and with lower incidence, also strong but sensitive to the period examined (weakening as the window lengthened from July-August to July-October). The association with self-reported masking was positive but modest, and masking did not meaningfully mediate the link between internet access and incidence or mortality, suggesting other protective pathways such as remote work, telehealth and reduced exposure. SSM - Population Health PubMed 39866855 10.1016/j.ssmph.2025.101747 https://www.sciencedirect.com/science/article/pii/S2352827325000011
Assessing the role of socioeconomic factors-income, education, broadband access, and healthy foods on location-wise disparities in COVID-19 cases Chakraborty, A; Shah, J 2025 Other Linking Gap and Impact Yes N/A Favorable Higher income, education level and broadband speed each reduced the probability of violating recommended preventive measures, promoted health awareness, and lowered COVID-19 cases. Conversely, low access to healthy foods increased case counts. The study also reports findings on food habits, living conditions and the link between education and broadband access. Archives of Public Health PubMed 10.1186/s13690-025-01510-w https://link.springer.com/article/10.1186/s13690-025-01510-w
Impact of loneliness on cancer mortality: a systematic review and meta-analysis Cheng, S; Yi, J; Pace, K; Santiago, A; Johnny, C; Nunez, JJ; Jomy, J; Raman, S 2025 Meta Analysis Linking Gap and Impact Yes N/A Yes Yes Cancer Favorable Loneliness and social isolation were associated with increased all-cause mortality (HR 1.34) and cancer-specific mortality (HR 1.11) among cancer patients across 16 studies (mean age 63). Described by the authors as the first systematic review and meta-analysis on this question. BMJ Oncology Google Scholar 10.1136/bmjonc-2025-000840 https://doi.org/10.1136/bmjonc-2025-000840
Psychosocial Factors And Heart Failure: Impact On Clinical Outcomes Okwueze, T 2026 Other Linking Gap and Impact Yes N/A Yes Chronic Heart Failure Favorable Psychosocial factors were found to critically influence the heart-failure trajectory, and addressing them improved quality of life, rehospitalization rates and mortality. No pooled effect estimates were reported. Journal of Cardiac Failure Google Scholar 10.1016/j.cardfail.2025.11.009 https://doi.org/10.1016/j.cardfail.2025.11.009
Systematic Review on the Association of Loneliness and Social Isolation With Diabetes Mellitus Puntscher, S; Papon, V; Spagl, S; Arvandi, M; Jahn, B; Pitkälä, KH; Coll-Planas, L; Holmerova, I; Bartova, A; Novotna, B 2025 Systematic Review Linking Gap and Impact Yes N/A Diabetes Favorable The review examined the association of loneliness and social isolation with diabetes mellitus. Evidence from longitudinal studies indicates that loneliness and social isolation are associated with an increased risk of T2DM. Value in Health Google Scholar 10.1016/j.jval.2025.09.1354 https://doi.org/10.1016/j.jval.2025.09.1354
The association of Alzheimer’s disease genetic risk with social connectedness in Middle-and Older-Ages Zimmerman, SC; Chen, R; Thoma, M; Pacca, L; Hebert, J; Riley, A; Kim, MH; Pederson, A; Yang, Y; Buto, P 2025 Other Linking Gap and Impact Yes N/A Yes Yes Dementia Neutral A higher Alzheimer's disease genetic risk score was associated with less social isolation — an association that strengthened with age — and with greater relationship satisfaction, among 487,194 UK Biobank participants aged 40 and over. The authors cautioned against reverse causation in interpreting isolation as a dementia risk factor. American Journal of Epidemiology Google Scholar 10.1093/aje/kwaf122 https://doi.org/10.1093/aje/kwaf122
Patterns of Social Exclusion and Depression Levels Among Older Adults in South Korea Moon, S; Lee, Y; Chung, S; Park, K 2025 Other Linking Gap and Impact Yes N/A Yes No Favorable Social exclusion was significantly associated with individual well-being and depression among older adults in South Korea, with distinct patterns of exclusion identified. Innovation in Aging Google Scholar 10.1093/geroni/igaf122.1133 https://doi.org/10.1093/geroni/igaf122.1133
A Systematic Review of the Impact and Outcome of Loneliness and Self-Isolation on Individuals Living With Cardiovascular Disease Okeke, C; Ojo, A; Ngige, O; Amuchie, C; Obi, C; Charles, O; Ekeocha, I; Konyeme, D; Idion, K; Balogun, F; Onwuchekwa, I; Ugo-Ihanetu, E; Okafor, G; Ogona, D; Okoye, C; Igboanugo, S 2025 Systematic Review Linking Gap and Impact Yes N/A Yes Yes Cardiovascular Disorders Favorable Loneliness and social isolation were linked to worse CVD mortality, stroke, heart failure and readmission across 13 studies totalling 63,978 participants. Cureus PubMed 40291206 10.7759/cureus.81277 https://doi.org/10.7759/cureus.81277
Impact of sporting, cultural and social events on emergency admissions: a retrospective multicenter study Fritsch, M; Brossard, C; Akplogan, M; Bouquet, P; Dib, C; Schnee, A; Goetz, C; Abensur Vuillaume, L 2025 Other Linking Gap and Impact Yes N/A Yes Yes Neutral The study tested the association between special-event days and daily ED admissions at two French emergency departments between 2010 and 2019. No effect estimates were reported. BMC Emerg Med PubMed 41163178 10.1186/s12873-025-01370-1 https://doi.org/10.1186/s12873-025-01370-1
A systematic review and meta-analysis on association between social non-participation and falling in depressive state among the older adult people Das, P; Saha, S; Das, T; Das, P; Roy, R; Roy, T 2025 Meta Analysis Linking Gap and Impact Yes N/A Yes No Mental Health Favorable A significant positive association was found between social non-participation and depression in older adults, suggesting social participation may alleviate depressive symptoms. Discov Ment Health PubMed 40694150 10.1007/s44192-025-00255-w https://doi.org/10.1007/s44192-025-00255-w
Human-pet interaction and well-being in mid-to-later adulthood: moderating roles of neuroticism and anxious attachment Wang, Y; Tsai, C; Liu, C 2025 Other Linking Gap and Impact Yes N/A Yes Yes Unfavorable Higher neuroticism was linked to lower well-being as pet-interaction time increased, among 232 Taiwanese adults aged over 45. BMC Public Health PubMed 41102658 10.1186/s12889-025-24571-6 https://doi.org/10.1186/s12889-025-24571-6
Association between cumulative loneliness and risk of cardiovascular diseases in middle-aged and older adults: A longitudinal study Hu, Z; Tang, L; Zhan, Y 2025 Other Linking Gap and Impact Yes N/A Yes Yes Cardiovascular Disorders Favorable Cumulative loneliness over 4 years was associated with increased 5-year CVD risk among 8,353 CHARLS participants aged 45 and older. Public Health PubMed 39836996 10.1016/j.puhe.2024.12.048 https://doi.org/10.1016/j.puhe.2024.12.048
Breaking the vicious cycle: Reciprocal influences between social isolation and functional disability and the buffering effect of digital inclusion Cui, M; Liu, Y; Yang, M; Miura, K; Zhang, J; Anme, T 2025 Prosp Cohort Study Linking Gap and Impact Yes N/A Yes No Favorable Social isolation and functional disability were bidirectionally associated across three waves among 480 Japanese adults aged 65 and older, with the isolation-to-disability path the stronger of the two. Digital inclusion buffered the effect. Arch Gerontol Geriatr PubMed 40294578 10.1016/j.archger.2025.105871 https://doi.org/10.1016/j.archger.2025.105871
Hearing Loss and Subjective Well-Being Among Older Adults: Mediating Effect of Social Activity and Cognitive Function Cao, X; Yang, B; Zhou, J 2026 Other Linking Gap and Impact Yes N/A Yes No Favorable Hearing loss was negatively associated with subjective well-being among 11,949 older Chinese adults, partly through social activity and cognitive function in serial mediation. Clin Gerontol PubMed 37489052 10.1080/07317115.2023.2240337 https://doi.org/10.1080/07317115.2023.2240337
Echoes of Home: The Impact of Acculturative Stress on Nigerian Students in Northern Cyprus, Investigating the Role of Loneliness and Social Support Jarrar, Y; Nweke, G 2025 Other Linking Gap and Impact Yes N/A No Yes Favorable Acculturative stress predicted depression among 392 Nigerian international students in Northern Cyprus, partially mediated by loneliness and moderated by perceived social support. Behav Sci (Basel) PubMed 40150183 10.3390/bs15030289 https://doi.org/10.3390/bs15030289
Social Determinants of Quality of Life in the Last Year of Life Among Community-Dwelling Older Adults with Multimorbidity Ginggeaw, S; LeBlanc, R; Chung, J 2025 Other Linking Gap and Impact Yes N/A Yes No Mental Health Favorable Social capital was positively and significantly associated with quality of life in the last year of life (β = 0.378, 95% CI 0.099–0.657, SE = 0.139), as were mental conditions (β = 0.614, 95% CI 0.167–1.062, SE = 0.194), among 230 older adults with multimorbidity drawn from 3,085 NHATS respondents aged 65 and older. Social capital functioned as a complementary mediator, partially mediating the relationship between mental conditions and QOL. The authors concluded that social capital has potential to enhance end-of-life quality of life, particularly through its influence on mental health. Clinical Nursing Research, Vol. 34, Issue 2 Google Scholar 10.1177/10547738241304575 https://doi.org/10.1177/10547738241304575
Group Yoga and Exercise Facilitated a Sense of Belonging for Participants with Acquired Brain Injury: A Qualitative Study Alsubaie, L; Schmid, A; Stephens, J; Weaver, J 2025 Other Linking Intervention and Impact Yes Participants with acquired brain injury attended either in-person group yoga or group low-impact exercise, meeting twice weekly for 1 hour over 8 weeks at a university-affiliated health center. Yes Neurologic Disorders Favorable Twenty-two of the 29 pilot RCT participants took part in interviews or focus groups. Two themes emerged: a non-judgmental, supportive environment fostered community connection and social interaction, and empowerment through group activities supported life skills and personal development. Participants described a sense of belonging, suggesting group yoga and exercise may support social cognition after ABI. Archives of Physical Medicine and Rehabilitation Google Scholar https://www.sciencedirect.com/science/article/pii/S0003999325002011
Plasma BDNF in burnout-related depressive disorders: The mediating role of perceived social isolation and the biopsychological effect of a multimodal inpatient treatment La Marca, R; Scheiwiller, M; Pfaff, M; La Marca-Ghaemmaghami, P; Böker, H 2025 Other Linking Intervention and Impact Yes Inpatients with a burnout-related depressive disorder received multimodal inpatient treatment at a specialized burnout clinic. Self-report measures of depression severity, burnout, loneliness and social isolation, plus the clinician-administered HAMD-17, were collected after admission and before discharge. Yes Mental Health Favorable Inpatients (n = 35) exhibited lower plasma BDNF levels than 21 matched healthy controls (U = 267.00, p = .045). Multimodal inpatient treatment significantly increased BDNF (z = −1.974, p = .024), and the change in BDNF was inversely related to the change in depression severity (HAMD-17: rs = 0.30, p = .042). This association was significantly mediated by perceived social isolation, supporting the neurotrophic hypothesis and pointing to social integration as an intervention focus. Journal of Affective Disorders Reports Google Scholar https://doi.org/10.1016/j.jadr.2025.100880
Effectiveness of a Community-Based eHealth Program on Self-Care, Cognition, and Health Outcomes of Older Adults With Chronic Diseases: A Multi-Site Cluster-Controlled Trial Wu, XV; Yap, XY; Feng, RC; Tan, YQ; Dong, Y; Tan, PC; Han, TY; Chao, FFT; Loh, LX; Tam, WSW 2026 Other Linking Intervention and Impact Yes Participants received a 12-week Community-based eHealth Program (CeHP) comprising 7 in-person sessions at Active Ageing Centres plus 5 virtual sessions delivered through the Care4Senior App. Yes No Neutral The 12-week CeHP produced a significant effect on cognitive processing speed and healthy aging among 108 community-dwelling older adults with chronic diseases (61 intervention, 47 control), but no significant difference on other health outcomes. The authors noted that disparities in digital access, technological proficiency and eHealth literacy continue to affect vulnerable older adults, and called for eHealth interventions and support systems that minimize barriers to uptake. Journal of the American Medical Directors Association Google Scholar https://www.sciencedirect.com/science/article/pii/S1525861025004736
The Relationship Between Social Support from Nursing Home Administrators and Psychological Well Being of Elderly People Living in Nursing Home Arini, W 2025 Prosp Cohort Study Linking Intervention and Impact Yes N/A Yes Favorable Social support from nursing home administrators was significantly associated with the psychological well-being of elderly residents (p < 0.001, r = 0.697). The finding supported the hypothesis that administrator-provided social support relates to psychological well-being among elderly individuals residing in nursing homes. International Journal of Research Publications Google Scholar 10.47119/IJRP1001691320257694 https://www.ijrp.org/paper-detail/7578
Online Conversations for Cognitive Health: A Culturally Adapted Intervention for Older Chinese Immigrants Yu, K; Mar, A; Lin, S; Duff, K; Silbert, L; Dodge, H 2025 Other Linking Intervention and Impact Yes Older Chinese immigrants received the culturally-adapted C-CONECT video-chat conversation program, delivered in 30-minute sessions four times weekly for 6 weeks. Yes No Favorable Chat completion reached 90% and 62% of participants reported reduced depressive symptoms in a pilot of the C-CONECT video-chat intervention among eight older Chinese immigrants (mean age 76). Innovation in Aging Google Scholar 10.1093/geroni/igaf122.193 https://doi.org/10.1093/geroni/igaf122.193
Wired for companionship: a meta-analysis on social robots filling the void of loneliness in later life Mehrabi, F; Ghezelbash, A 2025 Meta Analysis Linking Intervention and Impact Yes Older adults received AI-enabled social robots intended to reduce loneliness, across 19 pooled studies (N = 1,083). Yes No Favorable Social robots significantly reduced loneliness across 19 studies (N = 1,083), with larger effects in controlled studies and in institutional settings. Gerontologist PubMed 41025480 10.1093/geront/gnaf219 https://doi.org/10.1093/geront/gnaf219
Social isolation, loneliness, and incidence of type 2 diabetes mellitus: a systematic review and meta-analysis Asif, M; Asif, A; Rahman, UA; Ajmal, H; Jafar, U; Fatima, O 2025 Meta Analysis Linking Gap and Impact Yes N/A Yes Yes Diabetes Favorable Pooled analyses revealed a significant association between social isolation and T2DM, and the authors concluded that loneliness and social isolation are significant, independent risk factors for incident T2DM. Psychosocial factors were described as influencing risk through biological pathways (HPA-axis activation, heightened sympathetic activity, inflammatory mediators) and behavioural pathways (poor diet and weight regulation, inadequate physical activity, elevated tobacco use, suboptimal sleep). Primary Care Diabetes Google Scholar 40118745 10.1016/j.pcd.2025.03.006 https://doi.org/10.1016/j.pcd.2025.03.006
Impact of social isolation on change in brain volume in community-dwelling older Japanese people: the NEIGE study Murayama, H; Iizuka, A; Machida, M; Amagasa, S; Inoue, S; Fujiwara, T; Shobugawa, Y 2025 Other Linking Gap and Impact Yes N/A Yes No Favorable Individuals with a social contact frequency of less than once per week showed a greater decrease in hippocampal volume than those with contact four or more times per week, among 279 community-dwelling Japanese adults aged 65–84 imaged at baseline (2017) and follow-up (2021). No corresponding association was observed for total gray matter volume. Archives of Gerontology and Geriatrics Google Scholar https://www.sciencedirect.com/science/article/abs/pii/S0167494324003182
Association of social isolation, loneliness and risk of cardiovascular diseases: Meta-analysis of cohort studies Wang, L; Pan, H; Cai, Z; Li, X; Luo, L 2025 Meta Analysis Linking Gap and Impact Yes N/A Yes Yes Cardiovascular Disorders Favorable Pooled analysis revealed a heightened risk of CVD among individuals experiencing social isolation or loneliness (HR 1.17, 95% CI 1.10–1.25, I² = 85.1%, p < 0.001) across six cohort studies totalling 5,253,128 participants with 4 to 11.3 years of follow-up. Subgroup analysis indicated a slightly higher risk for social isolation than for loneliness (HR 1.39, 95% CI 1.15–1.68, I² = 90.2%, p = 0.001). BMC Public Health Google Scholar 40993644 10.1186/s12889-025-24300-z https://doi.org/10.1186/s12889-025-24300-z
Association of loneliness and social isolation with excess risk of cardiovascular events in people with obesity: a prospective cohort study Zhou, Y; Chen, R; Xu, M; Gong, Y; Liu, C; Wang, M; Yin, X 2025 Prosp Cohort Study Linking Gap and Impact Yes N/A Yes Yes Favorable Excess risk of CVD events among obese compared with non-obese people progressively decreased as baseline levels of loneliness and social isolation fell, across 432,767 UK Biobank participants over a median 12.48 years of follow-up. Obese individuals with the lowest versus highest baseline levels of loneliness and social isolation had 29% and 15% lower excess risk of obesity-related CVD events respectively. Journal of Global Health Google Scholar 41039880 10.7189/jogh.15.04241 https://doi.org/10.7189/jogh.15.04241
The Association Between Social Isolation/Loneliness and Unhealthy Behaviours among Individuals with Chronic Conditions: A Systematic Yang, M 2025 Systematic Review Linking Gap and Impact Yes N/A Yes Favorable More than half of the 23 included studies observed an increasing trend in smoking and alcohol use among people with chronic disease and older adults at risk of developing chronic disease. The authors concluded that social isolation and loneliness are negatively associated with unhealthy behaviours in these populations. Journal of Clinical Medicine Research Google Scholar 10.32629/jcmr.v6i3.4440 https://front-sci.com/journal/article?doi=10.32629/jcmr.v6i3.4440
Effects of Social Isolation on Mortality in Older Adults: Do Age and Gender Matter? Li, L; Kayser, J; Song, K 2025 Other Linking Gap and Impact Yes N/A Yes No Favorable Both measures of social isolation significantly predicted mortality among 7,186 community-living NHATS respondents, of whom a weighted 28.5% had died by 2023, though Pohl's measure demonstrated a stronger effect than Cudjoe's. Only Pohl's measure showed a significant interaction with gender (F[2, 55] = 4.67, p = .01). Mortality risk was 56% higher for somewhat-isolated men and 2.1 times higher for very-isolated men; among women it was 33% higher for the very-isolated. Innovation in Aging Google Scholar 10.1093/geroni/igaf122.3109 https://doi.org/10.1093/geroni/igaf122.3109
Loneliness, social isolation, and biological aging: Evidence from two large population-based cohort studies Wang, R; Yin, X; Chen, Y; Wang, X; Shi, M; Zhang, Y 2026 Prosp Cohort Study Linking Gap and Impact Yes N/A Yes Yes Favorable Higher levels of loneliness and social isolation were associated with increased risk of accelerated biological aging in the UK Biobank. Using KdmAge, loneliness scores of 1 and 2 carried adjusted ORs of 1.03 (95% CI 1.01–1.04) and 1.12 (95% CI 1.08–1.15) versus a score of 0; for social isolation the ORs were 1.04 (95% CI 1.02–1.05) and 1.13 (95% CI 1.10–1.16). PhenoAge and HD Age gave consistent results, supported by findings from NHANES III. Accelerated biological aging significantly mediated the link between loneliness/isolation and all-cause mortality. Journal of Affective Disorders Google Scholar 10.1016/j.jad.2026.121690 https://www.sciencedirect.com/science/article/abs/pii/S0165032726005410
Social Isolation Increases Emergency Department Use Among Older Adults Gettel, C; Salah, W; Rothenberg, C; Lee, J; Melady, D; Rising, K; Venkatesh, A 2025 Other Linking Gap and Impact Yes N/A Yes No Favorable Socially isolated older adults averaged 67.8 ED visits per 100 beneficiary-years compared with 47.9 among those living with a spouse (P < 0.001), roughly 40% higher, across 25,885 Medicare beneficiaries and 47,741 beneficiary-years. Of these, 25,394 lived with a spouse and 22,347 lived alone; participants were predominantly female (53%) and white (86%), mean age 75. The pattern held for both men and women. The authors suggested that screening for social isolation and connecting individuals to community resources could reduce emergency care utilization. Annals of Emergency Medicine Google Scholar 10.1016/j.annemergmed.2025.06.066 https://www.annemergmed.com/article/S0196-0644(25)00446-9/fulltext
Assessment of social isolation and changes in Parkinson’s disease symptoms during the COVID-19 pandemic: A longitudinal study Mehta, A; Ng, SY; Neo, SX; Chia, NS; Saffari, ES; Shivashanmugam, T; Choi, X; Heng, DL; Xu, Z; Tay, K 2025 Other Linking Gap and Impact Yes N/A Yes Yes Neurologic Disorders Favorable Mean LSNS-R scores decreased (p = 0.014) and the proportion classified as socially isolated increased (p < 0.001) during COVID-19 restrictions among 80 Parkinson's disease patients. The change was not uniform: 35% showed improved scores while 65% worsened or were unchanged. The regression model was significant in strata 1 (R² = 0.806, p = 0.001), with age, marital status and isolation status associated with LSNS-R change. Declining social network scores were associated with worsening motor and non-motor PD symptoms. Small cohort (n = 80). Clinical Parkinsonism & Related Disorders Google Scholar 39758705 10.1016/j.prdoa.2024.100293 https://doi.org/10.1016/j.prdoa.2024.100293
Social Isolation, Social Support, and Cardiovascular Disease Outcomes and Risk Prediction: The Atherosclerosis Risk in Communities Study Ababulgu, SN; Hu, X; Matsushita, K; Cudjoe, T; Kucharska-Newton, A; Peter-Marske, K; Aryee, E; Ndumele, C; Mathews, L 2025 Prosp Cohort Study Linking Gap and Impact Yes N/A Yes Yes Cardiovascular Disorders Neutral High versus low social isolation was significantly associated with greater all-cause mortality (HR 1.77, 95% CI 1.46–2.15) but not with CVD risk (HR 1.13, 95% CI 0.86–1.49) among 11,070 ARIC adults over a mean 21.5 years, during which 37% developed CVD and 60% died. The lowest versus highest quartile of social support showed the same pattern (mortality HR 1.28, 95% CI 1.20–1.37; CVD HR 1.05, 95% CI 0.96–1.14). Adding both measures to the PREVENT score did not improve risk discrimination or calibration, suggesting social connection may influence health through pathways already represented in current clinical models. Circulation, Vol. 152, Suppl. 3 (AHA 2025 Scientific Sessions abstract) Google Scholar 10.1161/circ.152.suppl_3.4364213 https://www.ahajournals.org/doi/abs/10.1161/circ.152.suppl_3.4364213?doi=10.1161/circ.152.suppl_3.4364213
Social Isolation and Depression in Community Dwelling Older Adults Anderson, L; Chen-Edinboro, L; Orwig, D; Wagner, F 2025 Other Linking Gap and Impact Yes N/A Yes No Neutral Mild social isolation carried 24% greater odds of depression compared with no social isolation (OR 1.24, 95% CI 1.07–1.43, p < 0.01) in fully adjusted models among 6,802 NHATS participants aged 65 and older. Severe social isolation showed borderline significance in bivariate analysis (OR 1.37, 95% CI 0.99–1.89, p = 0.054) but became non-significant after controlling for sociodemographic and health factors. The authors called for longitudinal studies. Directionally mixed. Innovation in Aging Google Scholar 10.1093/geroni/igaf122.1628 https://doi.org/10.1093/geroni/igaf122.1628
Social isolation and cardiovascular disease: mediation by health behaviors and metabolic factors Teppo, E; Etholén, A; Harkko, J; Boch, J; Speyer, P; Vähäsarja, L; Pietiläinen, O; Jousilahti, P; Lallukka, T 2025 Other Linking Gap and Impact No N/A Yes Yes Cardiovascular Disorders Unfavorable The total effect of social isolation on CVD was null (RR 1.01) over 22 years of Helsinki Health Study follow-up, and mediation via health behaviours and metabolic factors was minimal. Social isolation was nonetheless associated with physical inactivity and low fruit and vegetable intake. Preprint; not yet peer reviewed. medRxiv (preprint) Google Scholar 10.1101/2025.08.18.25333293 https://www.medrxiv.org/content/10.1101/2025.08.18.25333293v1
Cardiovascular Implications of Loneliness and Social Isolation: Evidence From a Systematic Review Puntscher, S; Spagl, S; Arvandi, M; Jahn, B; Pitkälä, KH; Coll-Planas, L; Holmerova, I; Bartova, A; Novotna, B; Casajuana-Kögel, C 2025 Systematic Review Linking Gap and Impact Yes N/A Yes Yes Cardiovascular Disorders Favorable Fifteen of 21 included studies reported statistically significant associations between loneliness and/or social isolation and CVD, five found no significant effect, and one reported a significant protective effect of social isolation. Studies drew on samples of 2,616 to 938,588 participants across the UK, US, Australia, China, Japan, Denmark and one multinational setting; stroke (n = 15) and myocardial infarction (n = 12) were the most frequently reported outcomes. All but one were rated high quality on the Newcastle-Ottawa Scale. The authors concluded greater attention should go to interventions reducing loneliness and isolation. Value in Health, Vol. 28, Issue 12, Supplement 1, S269 Google Scholar 10.1016/j.jval.2025.09.1166 https://www.valueinhealthjournal.com/article/S1098-3015(25)03723-4/fulltext
Racial and Ethnic Disparities in the 11-Year Bidirectional Relationship Between Dementia and Social Isolation Among Community-Dwelling Older Adults Hou, T; Liu, M; Wu, B; Ho, MH; Lin, CC 2025 Other Linking Gap and Impact Yes N/A Yes No Dementia Favorable Dementia and social isolation were found to be bidirectionally associated across 11 years of NHATS data: dementia increased isolation, most notably among non-Hispanic whites, while isolation elevated dementia risk across all racial and ethnic groups. American Journal of Geriatric Psychiatry Google Scholar https://www.ajgponline.org/article/S1064-7481(25)00113-7/abstract
" Empower and be empowered": Unveiling how community engagement influences residents' perceived health in high-density high-rise housing Chen, W; Wang, Y; Jian, IY; Mo, KH 2026 Other Linking Gap and Impact Yes N/A Yes Favorable Community engagement improved residents' perceived health in high-density high-rise housing, mediated by community satisfaction and collective learning, which in turn reduced isolation and enhanced self-efficacy. Social Science & Medicine Google Scholar https://www.sciencedirect.com/science/article/pii/S0277953626000900
Isolation and Stroke: A Retrospective Analysis of Outcomes Amidst Solitude Austin, H; Sharma, S 2025 Other Linking Gap and Impact Yes N/A Yes Stroke Favorable Social isolation and loneliness were identified as known stroke risk factors and may be linked to worse functional outcomes following stroke; prior animal work showed socialization improved outcomes. Stroke Google Scholar 10.1161/str.56.suppl_1.TP127 https://doi.org/10.1161/str.56.suppl_1.TP127
Social Isolation, Loneliness, and Pace of Aging Among Older Adults in the English Longitudinal Study of Ageing Shi, Y; Balachandran, A; Pei, H; Belsky, D 2025 Other Linking Gap and Impact Yes N/A Yes Yes Neutral Baseline loneliness, but not social isolation, predicted a faster Pace of Aging among 5,659 ELSA participants aged 50 and older, with stronger effects in men and adults under 70. Faster aging in turn predicted higher subsequent loneliness and social isolation, indicating a bidirectional relationship. Innovation in Aging Google Scholar 10.1093/geroni/igaf122.4010 https://doi.org/10.1093/geroni/igaf122.4010
Impact of Documented Social Vulnerability on Clinical Outcomes in Metabolic Dysfunction‐Associated Steatotic Liver Disease Danpanichkul, P; Pang, Y; Inggriani, M; Sirimangklanurak, S; Souza, M; Anouti, A; Ibrahim, AF; Duong, N; Cotter, TG; Kerr, TA 2026 Other Linking Gap and Impact Yes N/A Yes Favorable Documented social vulnerability was independently associated with higher risk of major adverse liver outcomes and cardiovascular events among patients with MASLD in a TriNetX retrospective cohort. Liver International Google Scholar 41749065 10.1111/liv.70550 https://doi.org/10.1111/liv.70550
Association between loneliness and patient experience in a primary health care setting Hamovitch, E; McKellar, K; Spiro, G; Wodchis, WP 2026 Other Linking Gap and Impact Yes N/A Yes Favorable Lonely patients had significantly lower odds of positive experiences across multiple domains of primary care, including clinician listening, care coordination and support for self-management, in a cross-sectional survey of 2,673 Ontario primary care patients. Annals of Family Medicine Google Scholar 10.1370/afm.250417 https://doi.org/10.1370/afm.250417
Loneliness during the COVID-19 pandemic: A potential risk factor for post-pandemic cognitive decline in older adults without dementia Harb, A; Souza-Talarico, JN; Willey, G; Silva, FCD; Jesus, MCFD; Deberg, J 2025 Systematic Review Linking Gap and Impact Yes N/A Yes Yes Neutral Loneliness during COVID-19 was linked to subjective cognitive decline across eight studies of 10,449 cognitively unimpaired older adults aged 50 and over, though evidence from objective performance measures was limited. Dementia & Neuropsychologia Google Scholar 40469238 10.1590/1980-5764-DN-2024-0256 https://doi.org/10.1590/1980-5764-DN-2024-0256
Joint Associations of Sarcopenia and Social Isolation with Mortality: Two Prospective Cohort Studies across Different Cultural Contexts Li, J; Zhang, Z; Zhang, J; Wang, Y; Yu, H; Liu, G; Pan, A; Liao, Y; Geng, T 2025 Prosp Cohort Study Linking Gap and Impact Yes N/A Yes Yes Favorable Participants with both sarcopenia and high social isolation had the highest mortality risk compared with those with neither condition (HR 1.99, 95% CI 1.74–2.28 in CLHLS; HR 1.69, 95% CI 1.55–1.85 in UK Biobank). Over median follow-ups of 3.0 and 13.1 years, 8,249 and 26,670 deaths occurred among 14,363 Chinese and 385,910 European adults. The authors concluded the two conditions synergistically elevate mortality risk. Biomedical and Environmental Sciences Google Scholar 10.3967/bes2025.113 https://doi.org/10.3967/bes2025.113
Abstract TP085: The Gut-Brain Connection: Social Isolation and Dysbiosis in Aging Couture, L; Banerjee, A; Delevati Colpo, G; Eagen, P; Baskin, L; Cahuiche, A; Hoffman, M; Lee, J 2026 Other Linking Gap and Impact Yes N/A Yes Yes Favorable Social isolation scores were significantly positively correlated with the relative abundance of Blautia and Clostridiales and negatively correlated with Phocaea and Lachnospiraceae (FDR-adjusted p < 0.05) among 37 adults aged over 50, independent of age and sex. The authors reported a distinct microbiome signature among socially isolated versus socially interactive individuals and suggested targeted microbiome-based interventions. Downstream functional analysis was pending. Stroke Google Scholar 10.1161/str.57.suppl_1.TP085 https://doi.org/10.1161/str.57.suppl_1.TP085
Abstract A011: Poor cognitive function and social isolation contribute to cancer and Alzheimer’s Disease risk in midlife and older Black adults living in a persistent poverty community Mama, SK; Brown, X; Lowenstein, LM; Basen-Engquist, K; Rechis, R; McNeill, LH 2025 Other Linking Gap and Impact Yes N/A Yes Yes Favorable Social isolation was significantly higher among participants with cognitive impairment (T = 49.9 ± 7.9 vs 44.6 ± 1.1; p = .037) and among those reporting subjective cognitive decline (T = 50.4 ± 5.4 vs 44.4 ± 7.4; p = .030). Those with SCD also reported worse physical (p = .028) and mental (p = .021) health. Among the 50 Black adults aged 45 and older in an urban persistent-poverty community (mean age 66.6), 20.0% screened positive for cognitive impairment. Cancer Epidemiology, Biomarkers & Prevention Google Scholar 10.1158/1538-7755.DISP25-A011 https://doi.org/10.1158/1538-7755.DISP25-A011
Social Connectedness and Mental Health Outcomes in the Elderly Population Marliana, T; Astuti, NPW; Wijayantono, W 2026 Other Linking Gap and Impact Yes N/A Yes Yes Favorable Higher social connectedness was significantly associated with better mental health outcomes among 60 community-dwelling older adults aged 60 and above in East Jakarta, Indonesia. Respondents who maintained stronger social relationships and community engagement reported lower psychological distress and better emotional well-being. The authors highlighted the importance of strengthening social support systems and community-based programs for older adults. Formosa Journal of Multidisciplinary Research Google Scholar 10.55927/fjmr.v5i3.34 https://doi.org/10.55927/fjmr.v5i3.34
The Role of Social Connection, Race, and Income in Mental Health: A Cross-Sectional NHANES Analysis Jakobsen, G 2025 Other Linking Gap and Impact No N/A Yes Yes Favorable Friendship difficulty was strongly associated with sadness (RR 19.77) and anxiety (RR 14.12) among 9,367 nationally representative NHANES participants, and the relationship was bidirectional — sadness (RR 1.97) and anxiety (RR 19.16) predicted friendship difficulty. Multiracial identity was associated with higher risk of sadness (RR 1.77). Income had no effect on sadness or anxiety, though higher income was protective against friendship difficulty (RR 0.76). All results p < 0.01. Authorea (preprint) Google Scholar 10.22541/au.175138835.59637263/v1 https://doi.org/10.22541/au.175138835.59637263/v1
Social Support and Other Factors Affecting the Quality of Life of Women with HIV/AIDS Ganisia, A; Fathiyyah, N; Imeldawati, R; Kwarta, CP 2026 Other Linking Gap and Impact Yes N/A Yes HIV / AIDS Favorable A significant relationship was found between emotional support and quality of life (p = 0.01) among 92 women living with HIV/AIDS, alongside a further social support dimension; the role of instrumental support differed from that reported in comparable studies. The authors framed social support, particularly feeling praised, respected and emotionally supported by family, partners, friends and health workers, as crucial to wellbeing beyond antiretroviral treatment alone. Lontara Journal of Health Science and Technology Google Scholar https://jurnal.poltekmu.ac.id/index.php/lontarariset/article/download/618/408/3558
The Impact of Social Support, Self-Efficacy, and Self-Management on Quality of Life in Hemodialysis Patients Lee, HJ; Jang, EH 2025 Other Linking Gap and Impact Yes N/A End-Stage Renal Disease Favorable Quality of life was positively correlated with social support (r = .51, p < .001), self-efficacy (r = .59, p < .001), and self-management (r = .39, p < .001) among 125 patients undergoing hemodialysis. In hierarchical regression, social support (β = .33, p < .001) and self-efficacy (β = .38, p < .001) were significant predictors of quality of life, together accounting for 44% of the variance (F = 11.94, p < .001). Journal of Musculoskeletal Health, Vol. 32, No. 1 (Korean Society of Musculoskeletal Health) Google Scholar https://www.dbpia.co.kr/journal/articleDetail?nodeId=NODE12149008
The Role of Social Isolation in Shaping Health Outcomes in Older Adults: A Regional Analysis Falco, V; Wiles, L; Romero, J; Saligan, L 2025 Other Linking Gap and Impact Yes N/A Yes No Favorable Each one-unit increase in social isolation score (indicating being less socially isolated) was associated with a 1.16-point improvement in mental health scores. Innovation in Aging Google Scholar 10.1093/geroni/igaf122.4217 https://doi.org/10.1093/geroni/igaf122.4217
Show Me the Meaning of Being Lonely: Pathways from Cognitive Functioning to Loneliness and Social Isolation Grenko, L; Anquillare, E; Collins-Pisano, C; Lac, A 2025 Other Linking Gap and Impact Yes N/A Yes Yes Favorable Higher cognitive functioning predicted higher perceived quality of social relationships (β = .22), fewer mental health symptoms (β = −.25), greater frequency of social interaction (β = .22), but also higher self-reported loneliness (β = .18; all p < .001) among 4,337 community-dwelling older adults (mean age 67.6). Higher relationship quality predicted less isolation (β = .22) and less loneliness (β = −.14), while greater mental health symptoms predicted greater isolation (β = −.13) and loneliness (β = .66). Model fit was satisfactory (CFI = .97, RMSEA = .03). Innovation in Aging Google Scholar 10.1093/geroni/igaf122.3121 https://doi.org/10.1093/geroni/igaf122.3121
Longitudinal, prospective cohort study of social relationships and self-rated health in the Atherosclerosis Risk in Communities (ARIC) Study cohort and ARIC/Jackson Heart Study (JHS) shared cohort Peter-Marske, KM; Howard, AG; Evenson, KR; Berkeley, SJ; Maselko, J; Sims, M; Kucharska-Newton, A; Sullivan, KJ; Rosamond, WD 2025 Prosp Cohort Study Linking Gap and Impact Yes N/A Yes Yes Favorable High social isolation was associated with lower self-rated health both at baseline and across 28 years of follow-up among 10,855 ARIC participants (56% women, 24% Black, mean age 57), with SRH declining slightly faster than for low isolation. High support was associated with greater SRH throughout. Over 10 years, support remained stable while isolation increased; maintaining or increasing support was associated with greater SRH than decreasing or stable low support, though confidence intervals were wide. PLOS One Google Scholar 10.1371/journal.pone.0326196 https://doi.org/10.1371/journal.pone.0326196
Loneliness, Social Isolation, and Social Support and the Development of Type II Diabetes: A Systematic Review and Meta-Analysis Levis, B; Tsopmo, CN; Wong, V; Villeneuve, P 2025 Meta Analysis Linking Gap and Impact Yes N/A Yes Yes Diabetes Favorable Individuals experiencing loneliness (RR 1.27, 95% CI 1.21–1.34) or low workplace social support (RR 1.18, 95% CI 1.06–1.32) had significantly higher risk of developing T2DM across 18 included studies. Associations were positive but non-significant for social isolation (RR 1.21, 95% CI 0.98–1.49), low structural support (RR 1.10, 95% CI 0.98–1.23), and low functional support (RR 1.03, 95% CI 0.99–1.08). Carleton Undergraduate Journal of Science Google Scholar 10.22215/cujs.v5i1.5307 https://doi.org/10.22215/cujs.v5i1.5307
Can we perform allogeneic hematopoietic cell transplantation (HCT) safely in patients with limited social supports and substantial psychosocial complexity? Trad, N; Reynolds, M; Abdallah, M; Sloan, JM; Newcomb, R; D'Alotto, J; Vanderklish, J; Subhendu, N; Lee, M; Defilipp, Z 2025 Other Linking Gap and Impact Yes N/A Yes Hematologic Disorders Cancer Neutral Overall survival, cause of death (relapse versus non-relapse mortality), and incidence of acute and chronic GVHD were assessed among adults transplanted after HCT eligibility criteria on caregiver support and psychosocial complexity were liberalized. No comparative effect estimates were reported in the conference abstract. The study addressed persistent disparities in HCT access driven in part by requirements for 24/7 dedicated caregiver availability post-transplant. Blood Google Scholar 10.1182/blood-2025-4617 https://doi.org/10.1182/blood-2025-4617
Eating Disorder Social Network Density: Its Impact on Diagnosis and Recovery Boisvert, JA; Harrell, WA 2025 Other Linking Gap and Impact Yes N/A Yes Mental Health Unfavorable Social network density (knowing others with eating disorders) was highly predictive of ED diagnosis, including of multiple EDs, among 1,000 participants largely from North America and Europe; internet media exposure was equally impactful. Same-sex siblings and peers exerted the greatest influence, exceeding parents, other relatives and friends. Networks of supportive others were separately associated with recovery. Denser social connection operated here as a risk factor rather than a protective one. BJPsych Open Google Scholar 10.1192/bjo.2025.10202 https://doi.org/10.1192/bjo.2025.10202
The unmet psychological needs of people living with multiple myeloma and smouldering myeloma: a review of current approaches and future directions Tuckey, N; Iasiello, M; Ali, K; Yong, A; Wilson, S; Ryan, M; Scoleri, D; Cantley, M; Wardill, HR 2025 Other Linking Gap and Impact Yes N/A Yes Hematologic Disorders Cancer Neutral Psychological interventions tailored to myeloma and its precursor conditions were limited and generally lacked consumer co-design and implementation analysis; exercise interventions often omitted a psychological component. Caregivers were frequently excluded from psychosocial support programs. Depression and anxiety symptoms predicted poor or deteriorating quality of life. Clinical Lymphoma, Myeloma and Leukemia Google Scholar 10.1016/j.clml.2025.09.016 https://doi.org/10.1016/j.clml.2025.09.016
Recorded loneliness and adverse outcomes in older acute care inpatients receiving psychiatric assessment Joseph, M; Lockie, K; Mbazira, A; Stewart, R 2025 Other Linking Gap and Impact Yes N/A Yes No Neutral Recorded loneliness, present in 11.2% of 11,631 patients assessed, was associated with increased risk of emergency department attendance after adjustment, but with lower mortality and, among survivors, fewer hospitalisation days over 12-month follow-up. The authors suggested the counterintuitive mortality and hospitalisation findings may reflect under-recording in patients with more severe illness or cognitive disorders, and noted true prevalence is likely substantially higher than 11.2%. International Journal of Geriatric Psychiatry Google Scholar 10.1002/gps.70052 https://doi.org/10.1002/gps.70052
Loneliness in spinal cord injury: A systematic review and comparison with the general population O’Donnell, LM; Dorstyn, DS; Barclay, L 2025 Systematic Review Linking Gap and Impact Yes N/A Neutral Average UCLA loneliness scores for the pooled SCI/D sample and the general population were comparable, with both groups reporting moderate loneliness (gw = .01, 95% CI −.43 to .46, p = .951) across 13 observational studies (N = 3,029 adults with SCI/D). Associations between loneliness and demographic or SCI/D characteristics were inconsistent, although those who were lonely did report adverse health and social outcomes. The Journal of Spinal Cord Medicine Google Scholar 10.1080/10790268.2025.2593074 https://doi.org/10.1080/10790268.2025.2593074
The associations of premorbid social isolation and social support with self-rated health and heart failure outcomes in the atherosclerosis risk in communities (ARIC) Study Peter-Marske, KM; Howard, AG; Evenson, KR; Berkeley, SJ; Maselko, J; Sims, M; Russell, SD; Kucharska-Newton, A; Sullivan, KJ; Rosamond, WD 2025 Prosp Cohort Study Linking Gap and Impact Yes N/A Yes Yes Chronic Heart Failure Favorable Low overall social support was associated with a 5.8-point lower self-rated health value over time than high support (95% CI 7.8, 3.8) among 2,967 ARIC participants with incident HF hospitalization, with similar associations across support subtypes. Low belonging support was associated with greater days to first rehospitalization (HR 0.85, 95% CI 0.79–0.96) but not with mortality (HR 1.05, 95% CI 0.95–1.17). Social isolation was associated with greater all-cause mortality among females (HR 1.57, 95% CI 1.20–2.06) but not males. PLOS One Google Scholar 10.1371/journal.pone.0337517 https://doi.org/10.1371/journal.pone.0337517
Visual impairment and cognitive function in aging adults: sex and age differences in mediating effect of social isolation and depression Zheng, DD; Lee, DJ; Rundek, T; Lam, BL; Gregori, NZ; Curiel, RE; Loewenstein, DA 2025 Other Linking Gap and Impact Yes N/A Yes Yes Favorable Poor vision directly affected cognitive function and also operated indirectly through social isolation and depressive symptoms among 117,231 UK Biobank participants aged 40–70. The mediating effect via social isolation was stronger in older adults and in men, and largest in men aged 60–70; the effect via depressive symptoms was stronger in women and middle-aged adults, nearly double that seen in older adults. American Journal of Ophthalmology Google Scholar 10.1016/j.ajo.2025.02.043 https://doi.org/10.1016/j.ajo.2025.02.043
The Impact of Social Isolation and Loneliness on Health Outcomes After Traumatic Brain Injury: A Scoping Review Jung, W; Chernauskas, T; Wu, KC 2025 Other Linking Gap and Impact Yes N/A Yes Yes Neurologic Disorders Favorable Social isolation and loneliness after TBI were associated with worse health outcomes across the eight included studies, including higher rates of depression and PTSD, slower recovery, and reduced functional abilities. These psychosocial factors also contributed to increased morbidity and mortality and reduced quality of life. Innovation in Aging Google Scholar 10.1093/geroni/igaf122.3124 https://doi.org/10.1093/geroni/igaf122.3124
Association Between Loneliness and Social Isolation and Health Outcomes Among Cancer Survivors and Non-Cancer Controls Avis, NE; Crawford, S; Colvin, A Other Linking Gap and Impact Yes N/A Yes No Cancer Favorable Cancer survivorship did not predict greater social disconnection — case-control status was not significantly related to loneliness or social isolation. Loneliness and social isolation were negatively related to physical HRQL before but not after covariate adjustment, while the negative associations with mental HRQL remained significant. Both were positively associated with depressive symptoms, and loneliness alone with high anxiety. Apart from a stronger unadjusted PCS–loneliness association in controls, there was no effect modification by case-control status. Frontiers in Aging Google Scholar 10.3389/fragi.2026.1813024 https://doi.org/10.3389/fragi.2026.1813024
Health system related kidney supportive care interventions for adults with chronic kidney disease: A systematic review Dharmagunawardene, D; Kularatna, S; Halahakone, U; Purtell, L; Bonner, A; Healy, HG; Senanayake, S 2025 Systematic Review Linking Intervention and Impact Yes Included studies evaluated health system kidney supportive care interventions for adults with chronic kidney failure. Yes End-Stage Renal Disease Favorable Kidney supportive care interventions were found effective in improving patient outcomes, especially end-of-life care and symptom management, though significant gaps remained, across 60 included studies of which one-third were randomised controlled trials. The most common Effective Practice and Organisation of Care domain was care delivery (58/60); end-of-life care (33/60) and physical aspects of care (19/60) were the most common quality palliative care domains; multidisciplinary shared care featured in 26 studies; cultural (0/60) and ethical aspects (3/60) were least described. Journal of Renal Care PubMed 39639604 10.1111/jorc.12517 https://pubmed.ncbi.nlm.nih.gov/39639604/
Psychiatric Advance Directives: A Review of the Evidence Contreras, AR; Miner, SA; Harris-Gersten, ML; Siconolfi, D; Eberhart, NK 2025 Other Linking Intervention and Impact Yes Individuals with psychiatric conditions completed psychiatric advance directives — documents recording preferences for treatment, setting of care, points of contact and a decision-making surrogate before a mental health crisis — across community, inpatient and outpatient contexts. Mental Health Favorable Psychiatric advance directives were found to improve autonomy in decision-making, reduce coercion in crisis interventions, and lower involuntary hospitalization rates, and were legally recognized in many U.S. states and other countries. Barriers included inconsistent legal recognition across jurisdictions, lack of provider understanding and training, and low awareness among persons with psychiatric conditions. Promising practices included clinician training and awareness programs, facilitation with peer worker or clinician support, and clear legal mandates. The authors concluded that PADs are a promising tool for people with serious mental illness, but implementation requires clear legal guidance and clinician buy-in. Rand Health Quarterly Google Scholar 41031387 N/A https://pmc.ncbi.nlm.nih.gov/articles/PMC12479008
Effects of advance care planning for patients with advanced cancer: A meta-analysis of randomized controlled studies Zhang, S; Li, J; Zhang, Y; Hu, X 2025 Meta Analysis Linking Intervention and Impact Yes Included randomized controlled studies delivered advance care planning — discussing, documenting and deciding on end-of-life preferences — to patients with advanced cancer. Cancer Neutral Advance care planning significantly improved completion of advance directives (OR 7.93, 95% CI 2.76–22.77, p = 0.0001) and palliative care utilization (OR 1.39, 95% CI 1.08–1.78), but was not effective in improving anxiety, depression or decisional conflict. The authors concluded that ACP may have desirable impacts on advance directive completion and palliative care utilization for patients with advanced cancer. International Journal of Nursing Studies Google Scholar 40378812 10.1016/j.ijnurstu.2025.105096 https://pubmed.ncbi.nlm.nih.gov/40378812/
Advance Care Planning in German General Practice: A Longitudinal Qualitative Study on Patients' Expectations and Experiences Schmidt, A; Weckbecker, K; In Der Schmitten, J; Götze, K; Mortsiefer, A 2025 Other Linking Intervention and Impact Yes Ambulatory patients in German general practices received facilitated advance care planning provided by trained professionals. Favorable Participants valued comprehensive advance directives and structured ACP conversations in general practice. Key motivators for seeking facilitation were maintaining autonomy and reducing family burden. Trustworthy discussions with professional facilitators, structured guidance and clear communication — particularly involving healthcare proxies — were essential to a satisfying ACP process. Despite prior interest in discussing care preferences, some participants had still not initiated those conversations. Based on interviews with eight German ambulatory patients (six female, two male; mean age 63.6) across two general practices, conducted before, immediately after and 12 months after facilitation. Health Expectations Google Scholar 10.1111/hex.70392 https://pmc.ncbi.nlm.nih.gov/articles/PMC12358674/
How long-term care literacy impacts older adults’ preferences for future care services Wang, Z; Niu, B; Fukayama, K 2026 Other Linking Gap and Impact Yes N/A Yes Favorable Adequate care literacy was associated with preference for mixed or formal care services. Economic status, subjective health and community involvement also affected care preferences. The authors concluded that it is important to improve care literacy and support informed care choices among older adults. Geriatric Nursing Google Scholar 10.1016/j.gerinurse.2025.103775 https://www.sciencedirect.com/science/article/abs/pii/S0197457225006184
Socio-economic and insurance factors in preventive care: A two-stage weighted structural analysis Nkouaga, F 2025 Other Linking Gap and Impact Yes N/A Yes Favorable Individuals reporting higher satisfaction with insurance coverage, ongoing relationships with primary care providers, and greater financial literacy were more likely to engage in preventive health behaviors. Cost-related barriers were initially associated with increased utilization but their direct influence diminished once financial knowledge was accounted for. Once structural and informational dimensions were considered, traditional demographic variables such as race and gender lost statistical significance, underscoring the greater impact of systemic and educational factors. Dialogues in Health Google Scholar 10.1016/j.dialog.2025.100243 https://pmc.ncbi.nlm.nih.gov/articles/PMC12547269/
Digital health literacy and self-efficacy among older adults: Mediating roles of social support and life satisfaction and the moderating role of health consciousness Xin, Y; Luo, M 2026 Other Linking Gap and Impact Yes N/A Yes Favorable Digital health literacy was directly associated with self-efficacy (β = 0.21, p < .05) and indirectly associated through social support (β = 0.10, 95% CI 0.06–0.14) and life satisfaction (β = 0.17, 95% CI 0.12–0.22) among 1,016 community-dwelling older adults across six Chinese provinces. A sequential mediation pathway ran from digital health literacy to social support to life satisfaction to self-efficacy (β = 0.05, 95% CI 0.01–0.09). Health consciousness significantly moderated these relationships, with stronger associations among participants high in health consciousness (direct path β = 0.32 vs 0.09; sequential indirect path β = 0.06 vs 0.01). Qualitative analysis of 30 interviews identified information-processing strategies, social validation processes and goal-directed feedback loops that translated digital competencies into psychological resources. Digital Health Siren 10.1177/20552076261415930 https://doi.org/10.1177/20552076261415930
Psychosocial Predictors of Anxiety and Depression in Community-Dwelling Older Adults During a Prolonged Infectious Disease Crisis Kim, NH; Hong, SH; Park, HJ; Shin, SH 2025 Other Linking Gap and Impact Yes N/A Yes No Favorable Difficulties with social distancing, rather than fear of infection, were the strongest predictor of both anxiety and depression among 178 community-dwelling South Korean adults aged 65 and older. Emotional support was the strongest protective factor for both outcomes, while material support gave additional protection against depression only. Healthcare (Basel) Google Scholar 10.3390/healthcare14010048 https://doi.org/10.3390/healthcare14010048
The social microbiome of older people Ticinesi, A; Zuliani, G; Spaggiari, R; Volpato, S; Maggi, S; Franceschi, C 2025 Other Linking Gap and Impact Yes N/A Yes No Favorable Social contact was found to involve the sharing of gut microbial taxa in both animals and humans, and close contact with pets was associated with greater microbiome diversity. Social isolation and loneliness were linked to unfavorable shifts in gut microbiome composition, with pandemic-era studies pointing toward dysbiosis. Ageing Research Reviews Google Scholar 10.1016/j.arr.2025.103008 https://doi.org/10.1016/j.arr.2025.103008
Loneliness, Isolation, Cognition, and Mortality Risk: Harmonization Within a Coordinated Analysis Framework Yoneda, T; Jackson, K; Bedjeti, K; Muniz-Terrera, G; Mroczek, D; Steptoe, A; Ong, A; Graham, E 2025 Meta Analysis Linking Gap and Impact Yes N/A Yes Yes Favorable Across 11 longitudinal studies of aging (N > 110,000, 20 countries), loneliness and social isolation each predicted increased risk of dementia and death in Cox and logistic models (all p < 0.001), with social isolation particularly strongly linked to mortality. Between-study variability in how the two constructs were defined and modeled was identified as a major source of inconsistency in prior findings. Innovation in Aging Google Scholar 10.1093/geroni/igaf122.1683 https://doi.org/10.1093/geroni/igaf122.1683
Analyzing the Association of Social Capital and Sleep Quality of the Elderly Community Mohammadi, M; Mohammadnabizadeh, S; Varmaghani, M; Moodi, M; Shrifi, F; Shirazinia, M; Fakhrzadeh, H; Payab, M; Khorashadizadeh, M; Naderimagham, S 2025 Other Linking Gap and Impact Yes N/A Yes Yes Favorable Higher social capital was associated with better sleep quality among 1,348 community-dwelling adults aged 60 and older in Birjand County, Iran, with those in the highest social-capital quintile reporting the best sleep. Health Science Reports Google Scholar 10.1002/hsr2.70766 https://doi.org/10.1002/hsr2.70766
Variation of the risk associated with potentially modifiable risk factors for dementia between ethnic groups within one country. A retrospective cohort study using routinely collected health data in Aotearoa New Zealand Ma'u, E; Cullum, S; Cheung, G; Tamatea, J; Livingston, G; Mukadam, N 2025 Other Linking Gap and Impact Yes N/A Yes Yes Dementia Favorable Education, smoking, diabetes, depression, physical activity and social isolation were each associated with a 1.13–1.55 times increased risk of dementia. No association was demonstrated for hypertension, alcohol, or air pollution. Differences between ethnic groups were suggested but not confirmed due to limited power. The authors concluded that dementia prevention potential differs across ethnic groups in New Zealand through both differential prevalence and differential risk factor effects. International Journal of Geriatric Psychiatry Google Scholar 39780033 10.1002/gps.70042 https://doi.org/10.1002/gps.70042
Persistent Postpartum Depression During the COVID‐19 Pandemic and the Role of Social Supports Steward, CE; Claridge, AM; Beeson, T; Feeney, SL 2025 Other Linking Gap and Impact Yes N/A No Yes Mental Health Favorable Over 35% of 242 US respondents who gave birth during the COVID-19 pandemic reported symptoms consistent with clinical depression at 12–30 months postpartum. Lower household income, COVID-related worries during pregnancy, experiences of intimate partner violence, and lack of perceived access to informal supports each predicted depressive symptoms. Interviews with 12 participants highlighted the role of informal supports in postpartum wellbeing. Journal of Community Psychology Google Scholar 10.1002/jcop.70018 https://doi.org/10.1002/jcop.70018
Social support and epigenetic aging at the intersections of race, ethnicity, and gender: findings from NHANES 1999-2002 Shen, H; Gladish, N; Cardenas, A; Needham, BL; Rehkopf, DH 2025 Other Linking Gap and Impact Yes N/A Yes Yes Neutral The association between social support and epigenetic aging varied markedly across subgroups rather than showing a uniform effect. Sufficient emotional support was linked to slower epigenetic aging among Black men, having close friends among Black women, and being married among Black and Mexican American men. The Hannum and Weidner clocks were the most sensitive to social support variability. SSM - Population Health Google Scholar 41458453 10.1016/j.ssmph.2025.101892 https://doi.org/10.1016/j.ssmph.2025.101892
Social isolation and loneliness in non-communicable chronic diseases: Impact of COVID-19 pandemic, population aging and technological progress Guglielmi, V; Colangeli, L; Parrotta, ME; Ciammariconi, A; Milani, I; D'Adamo, M; Sbraccia, P; Capoccia, D 2025 Other Linking Gap and Impact Yes N/A Yes Yes Cardiovascular Disorders Diabetes Favorable Social isolation and loneliness were found to affect a significant portion of the older adult population, driven by decreased social interaction, chronic illness and sensory impairment; other vulnerable groups included people with psychiatric or disabling conditions, substance use, low socioeconomic status, unemployment, and ethnic or marginalized minorities. The authors concluded that isolation negatively affects the development, progression and management of NCDs, and that effective interventions must address both societal factors and healthcare-related needs. Nutrition, Metabolism and Cardiovascular Diseases Google Scholar 40189996 10.1016/j.numecd.2025.104015 https://www.sciencedirect.com/science/article/pii/S0939475325001693
Loneliness and isolation: Are they associated with the wish for an earlier end of life? Hajek, A; Zwar, L; Gyasi, RM; Yon, DK; Pengpid, S; Peltzer, K; König, HH 2025 Other Linking Gap and Impact Yes N/A Yes Yes Favorable Both loneliness (β = −1.47, p < 0.001) and social isolation (β = −1.49, p < 0.001) were robustly associated with a lower desired age at death among 3,826 community-dwelling German adults aged 43 and older (mean age 69.3; mean desired age at death 90.1 years). The loneliness association was particularly pronounced among men. Geriatrics & Gerontology International Google Scholar 10.1111/ggi.70148 https://doi.org/10.1111/ggi.70148
End-of-life Symptoms and Experiences of Loneliness and Social Isolation: A Nationally-Representative Survey Rosenberg, M; Cenzer, I; Smith, A; Kotwal, A 2025 Other Linking Gap and Impact Yes N/A Yes Yes Favorable Multiple symptoms, particularly pain and agitation, were associated with end-of-life loneliness, whereas depression and persistent cough were associated with both loneliness and social isolation. The authors concluded that the presence of such symptoms could prompt clinicians to explore loneliness and isolation and provide appropriate referrals, and that social interventions should be considered part of comprehensive symptom management. Journal of Pain and Symptom Management Google Scholar https://www.sciencedirect.com/science/article/pii/S0885392425001642
The level of Social Isolation and Loneliness among American Muslims aged 50 years and above and their associations with Depression, Morbidity, Self-rated Health, and Healthcare Utilization Alqam, B 2025 Other Linking Gap and Impact No N/A Yes Yes Favorable Social isolation was reported by 18.1% and loneliness by 21% of 105 American Muslims aged 50 and older (mean age 64, SD 9). Social isolation correlated with loneliness (β = .38, p < .001) and poorer self-rated health (β = .35, p < .001); loneliness was linked to worse self-rated health (β = .35, p = .003) and increased healthcare utilization (β = .27, p < .05). Depression mediated both associations, and no relationship was found with morbidity. University of Wisconsin-Milwaukee (doctoral dissertation) Google Scholar http://digital.library.wisc.edu/1793/95404
How Social Isolation Exacerbates Unmet Care Needs in Older Adults With Dementia Lin, Z; Lin, Z 2025 Other Linking Gap and Impact Yes N/A Yes No Dementia Favorable Socially isolated people living with dementia, particularly those severely isolated, had significantly higher rates of unmet care needs than socially integrated counterparts (N = 5,690, aged 65 and older). Disparities in access to supportive networks and differences in level of care need contributed, but severe isolation remained strongly associated with unmet needs after accounting for both. The authors concluded that reducing isolation could be key to addressing unmet care needs. Innovation in Aging Google Scholar 10.1093/geroni/igaf122.582 https://doi.org/10.1093/geroni/igaf122.582
Evaluating the Impact of Discrimination and Isolation in Patients with Hypertension in the Predicting Risk and Investigating Outcomes Using Patient-Reported Individual and Community-Level Data (PRIORITY) Cohort Roberts, V; Lopez, C; Maroko, A; Gordon, L; Wilder, M; Richardson, LD 2025 Other Linking Gap and Impact Yes N/A Yes Yes Cardiovascular Disorders Favorable Housing insecurity (OR 2.0, 95% CI 1.1–3.7), financial strain (OR 2.4, 95% CI 1.5–4.1), and loneliness or social isolation (OR 2.2, 95% CI 1.1–4.6) were each associated with higher odds of experiencing discrimination among 255 emergency department patients with hypertension (mean age 59; 38% Latine, 46% Black). Participants who were both socially isolated and un/underemployed had markedly higher odds (OR 10.3, 95% CI 1.42–215.0). Journal of Scientific Innovation in Medicine Google Scholar 10.29024/jsim.272 https://doi.org/10.29024/jsim.272
Longitudinal association of community and residential environment with the risk of cognitive impairment in middle-aged and older Chinese adults Zhang, Y; Ma, L; Zhao, J 2025 Prosp Cohort Study Linking Gap and Impact Yes N/A Yes Yes Favorable Better community and residential environments were associated with lower risk of incident cognitive impairment among 10,471 middle-aged and older adults followed from 2011 to 2020. Reduced risk was observed for garbage disposal services (HR 0.807), open-air fitness equipment (HR 0.834), accessibility for handicapped individuals (HR 0.948), presence of a social organization for older adults (HR 0.838), concrete and steel buildings versus adobe or other types (HR 0.813), running water supply (HR 0.847), broadband connectivity (HR 0.650), clean energy use (HR 0.957) and indoor tidiness (HR 0.875). Residing in relaxed rather than crowded residential environments was associated with a 3.8% higher risk (HR 1.038). The authors concluded that community and residential planning should prioritize both basic social and environmental factors and the internal built environment to help prevent cognitive impairment. Scientific Reports Google Scholar 10.1038/s41598-025-97512-3 https://www.nature.com/articles/s41598-025-97512-3
Factors influencing self-management and health-related quality of life in low-income patients with diabetes: a predictive model Pahn, J; Yang, Y; Kim, SH 2025 Other Linking Gap and Impact Yes N/A Diabetes Favorable Self-efficacy and self-management had significant direct effects on health-related quality of life; diabetes knowledge influenced HRQoL indirectly through self-efficacy. No variables showed a significant effect on HbA1c. International Journal of Nursing Studies Advances Google Scholar 40491900 https://doi.org/10.1016/j.ijnsa.2025.100349 https://pmc.ncbi.nlm.nih.gov/articles/PMC12145980/
Beyond Access: Digital Skills as a New Social Determinant of Health Among Older Adults—Evidence from a Longitudinal Panel Study Ji, H; Pan, W; Xin, J 2025 Prosp Cohort Study Linking Intervention and Impact Yes N/A Yes Favorable Self-rated digital skills robustly predicted improvements in physical, mental and social health among older adults; benefits operated via social participation, health behaviors and digital health engagement, with larger returns for vulnerable groups. Archives of Gerontology and Geriatrics PubMed 10.1016/j.archger.2025.106124 https://www.sciencedirect.com/science/article/abs/pii/S0167494325003784
Exploring the influence of health and digital health literacy on quality of life and follow-up compliance in patients with primary non-muscle invasive bladder cancer: a prospective, single-center study Keles, A; Somun, UF; Kose, M; Arikan, O; Culpan, M; Yildirim, A 2025 Prosp Cohort Study Linking Gap and Impact Yes N/A Cancer Favorable Poorer digital health literacy and health literacy were significantly associated with older age, lower educational attainment and lack of internet access. The findings suggested a link between DHL/HL levels and treatment adherence and quality of life in NMIBC patients. World Journal of Urology PubMed 39883268 10.1007/s00345-025-05463-1 https://pubmed.ncbi.nlm.nih.gov/39883268/
Impact of digital health literacy on quality of life among people with physical disabilities Niazy, SM; Abadi, NN; Radhi, MM; Al-Eqabi, QAK; AL-Thabhawee, GDM 2025 Other Linking Intervention and Impact Yes N/A Favorable Digital health literacy technology was significantly associated with both the use of e-health services (r=0.56) and quality of life (r=0.42). Regression analysis indicated that both DHL technology (β=0.28, p=0.003) and e-health use (β=0.39, p<0.001) significantly predicted quality of life. Mediation analysis revealed a statistically significant indirect effect (B=0.20) of digital health literacy technology on quality of life through the use of e-health services. Iranian Journal of War and Public Health PubMed 10.58209/ijwph.17.2.197 https://ijwph.ir/browse.php?a_id=1528&slc_lang=en&sid=1
Leveraging Technology and Data in Driving Health Literacy and Health Equity Garcia-Dia, MJ 2026 Other Linking Intervention and Impact N/A N/A Favorable Digital tools were found to offer unprecedented opportunities to disseminate health information and facilitate care, but their effectiveness was contingent on addressing underlying issues of digital access, ensuring cultural relevance, and empowering individuals to critically appraise information. The Informatics Guide to Healthcare (Book) PubMed https://www.taylorfrancis.com/chapters/edit/10.4324/9781003464457-5/leveraging-technology-data-driving-health-literacy-health-equity-mary-joy-garcia-dia
E-health literacy and attitudes toward internet health information in relation to self-care adherence among Korean patients with chronic obstructive pulmonary disease: a cross-sectional study Park, NY; Lee, I 2025 Other Linking Gap and Impact Yes N/A Chronic Lung Disorders Favorable E-health literacy correlated with all self-care components (r = .46–.59, p < .001) among 110 Korean COPD patients, as did attitudes toward internet health information (r = .45–.66, p < .001). E-health literacy was the strongest predictor of maintenance (B = 0.44) and monitoring (B = 0.45), while attitudes toward internet health information most strongly predicted management (B = 0.63). Models explained 27.4%–48.9% of variance. BMC Public Health Google Scholar 10.1186/s12889-025-25909-w https://link.springer.com/article/10.1186/s12889-025-25909-w
The effect of e-health literacy and patient–physician relationship on treatment adherence Boz, MK; Çimen, M 2025 Other Linking Gap and Impact Yes N/A Yes Favorable E-health literacy affected the patient-physician relationship, the patient-physician relationship affected treatment adherence, and e-health literacy affected treatment adherence, among 425 adults surveyed in Istanbul. The patient-physician relationship played a mediating role between e-health literacy and treatment adherence. Healthcare (Basel) Google Scholar 10.3390/healthcare13060632 https://doi.org/10.3390/healthcare13060632
Advance Care Planning, End-of-Life Preferences, and Burdensome Care: A Pragmatic Cluster Randomized Clinical Trial Wolff, JL; Scerpella, D; Giovannetti, ER; Roth, DL; Hanna, V; Hussain, N; Colburn, JL; Abshire Saylor, M; Boyd, CM; Cotter, V; McGuire, M; Rawlinson, C; Sloan, DH; Richards, TM; Walker, K; Smith, KM; Dy, SM 2025 RCT Linking Intervention and Impact Yes Trained facilitators engaged patients and families in a multicomponent primary care-based advance care planning initiative, supported by EHR tools and documentation aids, across 51 primary care practices in two health systems; control practices received usual care. Yes Neutral The initiative increased new EHR-documented end-of-life preferences but also increased potentially burdensome care at end of life among a subgroup of decedents with serious illness. Among 64,915 older patients at 51 primary care practices, 4.6% of those in intervention practices engaged in facilitator-led ACP. JAMA Internal Medicine PubMed 39621341 10.1001/jamainternmed.2024.6215 https://pmc.ncbi.nlm.nih.gov/articles/PMC11612918/
An Intervention to Increase Advance Care Planning Among Older Adults With Advanced Cancer: A Randomized Clinical Trial Volandes, AE; Chang, Y; Lakin, JR; Paasche-Orlow, MK; Lindvall, C; Zupanc, SN; Martins-Welch, D; Carney, MT; Burns, EA; Itty, J; Emmert-Tangredi, K; Martin, NJ; Sanghani, S; Tilburt, J; Pollak, KI; Davis, AD; Garde, C; Barry, MJ; El-Jawahri, A; Quintiliani, L; Sciacca, K; Goldman, J; Tulsky, JA 2025 RCT Linking Intervention and Impact Yes Patients received evidence-based video decision aids on advance care planning and their clinicians received communication skills training, delivered in ambulatory oncology clinics; control clinics received usual care. Yes Cancer Favorable Patients at clinics receiving the bundled intervention had significantly more ACP documentation than those at usual-care clinics (25.3% vs 20.8%) across 13,800 unique patients at 29 clinics in three health care systems, suggesting that video decision aids plus clinician communication training improve ACP documentation for older adults with advanced cancer. JAMA Network Open PubMed 40343696 10.1001/jamanetworkopen.2025.9150 https://pmc.ncbi.nlm.nih.gov/articles/PMC12065034/
Palliative Care Program for Community-Dwelling Individuals With Dementia and Caregivers: The IN-PEACE Randomized Clinical Trial Sachs, GA; Johnson, NM; Gao, S; Torke, AM; Hickman, SE; Pemberton, A; Vrobel, A; Pan, M; West, J; Kroenke, K 2025 RCT Linking Intervention and Impact Yes Caregivers received monthly calls from a trained nurse or social worker plus evidence-based protocols to manage neuropsychiatric symptoms, caregiver distress and palliative care issues including advance care planning, symptoms and hospice (n = 99); the control group received usual care with written dementia resource information (n = 102). Yes Dementia Neutral Dementia palliative care did not significantly improve neuropsychiatric symptoms through 24 months: NPI-Q severity was 9.15 versus 9.39 (between-group difference −0.24, 95% CI −2.33 to 1.84), with no significant difference in rate of change, among 201 enrolled dyads (patients 67.7% female, 43.3% African American, mean age 83.6). No significant differences were found in secondary outcomes except fewer combined ED and hospitalization events with palliative care (1.06 vs 2.37 events per patient; difference −1.31; RR 0.45). JAMA PubMed 39878993 10.1001/jama.2024.25845 https://pubmed.ncbi.nlm.nih.gov/39878993/
Models, components and outcomes of palliative and end-of-life care provided to adults living at home: A systematic umbrella review of reviews Pask, S; Okwuosa, C; Mohamed, A; Price, R; Young, J; Curtis, T; Henderson, S; Winter-Luke, I; Sunny, A; Chambers, RL; Greenley, S; Johansson, T; Bone, AE; Barclay, S; Higginson, IJ; Sleeman, KE; Murtagh, FE 2025 Systematic Review Linking Intervention and Impact Yes Included reviews evaluated seven models of palliative and end-of-life care for adults living at home, grouped by setting (in-home, outpatient), professional type (specialist, integrated, non-specialist) or mode (telehealth, education and training). Components included holistic person-centred assessment, skilled professionals, access to medicines, care and equipment, patient and family support, advance care planning, service integration, virtual and remote technology, and education. Favorable The 'in-home palliative care' model was the most researched, with good evidence of positive benefit, across 66 reviews screened from 6,683 papers. Specialist and integrated models showed evidence of improved patient and service-utilisation outcomes, while cost-effectiveness evidence was lacking. Meta-level evidence supported provision of in-home palliative care, with most review-level evidence showing a positive effect on patient outcomes. Palliative Medicine PubMed 40908745 10.1177/02692163251362567 https://journals.sagepub.com/doi/10.1177/02692163251362567
Effects of advance care planning on hope, anxiety, attitudes, and behavioral intentions in older adults with cancer: A randomized controlled study Hsu, YH; Wang, MH; Hu, WY; Ke, LS 2025 RCT Linking Intervention and Impact Yes Cancer patients aged over 65 received advance care planning conversations led by a trained nurse using a cartoon-based decision aid; the control group received standard care. Yes Cancer Neutral Herth Hope Index and ACP Attitude Scale scores did not differ significantly by group, time, or group × time among 72 older adults. STAI-S anxiety scores did not differ between groups, though both groups decreased significantly over time. The experimental group showed higher ACP behavioral intention scores over time than the control group. The authors concluded that fear of patient hopelessness should not be used to postpone ACP conversations. Supportive Care in Cancer PubMed 10.1007/s00520-025-09866-z https://link.springer.com/article/10.1007/s00520-025-09866-z
Serious Illness Conversations in the Emergency Department for Older Adults With Advanced Illnesses: A Randomized Clinical Trial Ouchi, K; Block, SD; Rentz, DM; Berry, DL; Oelschlager, H; Shiozawa, Y; Rossmassler, S; Berger, AL; Hasdianda, MA; Wang, W; Boyer, E; Sudore, RL; Tulsky, JA; Schonberg, MA 2025 RCT Linking Intervention and Impact Yes Patients received ED GOAL: SIC-trained research nurses delivered a motivational interview about serious illness conversations, a structured serious illness conversation, and communication priming for patients and their primary clinicians on a tablet computer in the emergency department or within one week of leaving; the control group received usual care. Yes Yes Cancer Dementia Neutral Medical record documentation of end-of-life values and goals was significantly higher in the intervention group at 3 months (24.3% vs 9.9%, p = .03) and 6 months (31.4% vs 12.7%, p = .008) among 141 randomized patients (mean age 66.7, 51.8% female, 60.3% metastatic cancer). At 1 month there was no difference in patient-reported ACP engagement (3.32 control vs 3.37 intervention, p = .58), though 17.1% of intervention patients versus 7.0% of controls had discussed care preferences with physicians (p = .07). JAMA Network Open PubMed 10.1001/jamanetworkopen.2025.16582 https://files-profile.medicine.yale.edu/documents/ceab390e-3a62-444c-b297-6b29251ce694
Care Consistency With Care Preferences in Nursing Homes: A Cluster-Randomized Study of the Effects of an Advance Care Planning Program (BEVOR) Götze, K; Bausewein, C; Chernyak, N; Feddersen, B; Fuchs, A; Hummers, E; Icks, A; Kirchner, Ä; Klosterhalfen, S; Kranefeld, N; Laag, S; Lezius, S; Meyer, G; Montalbo, J; Nauck, F; Pepić, A; Przybylla, S; Rosu, I; Schildmann, J; Schunk, M; Stanze, H; Stöhr, A; Thilo, N; Vogel, C; Zapf, A; Marckmann, G; in der Schmitten, J 2025 RCT Linking Intervention and Impact Yes Nursing homes received BEVOR, a complex advance care planning intervention addressing individual, institutional and regional levels through facilitator training, reliable ACP processes, organisational development and education of health professionals; control homes received no intervention. Yes Neutral Hospitalization rate did not differ between groups (IRR 1.0, 95% CI 0.97–1.1) and declined similarly in both during COVID-19, across 44 nursing homes of which 23 received the intervention. Care consistency with preferences was similar (OR 0.9, 0.4–1.9), though exploratory analysis suggested greater consistency in the 6 of 23 homes meeting adherence criteria (OR 1.9, 0.7–5.3). Written emergency plans were significantly more common in the intervention group (IRR 11.6, 8.2–16.4) and in adherent homes (IRR 30.1, 15.7–57.6). The authors noted the intervention did not permeate sufficiently, largely due to the pandemic, so the trial was not conclusive. Deutsches Arzteblatt International PubMed 40554660 10.3238/arztebl.m2025.0077 https://di.aerzteblatt.de/int/archive/article/245099
Evaluation of a Community-Based Advance Care Planning Campaign for a General Adult Population Zhang, P; Erbelding, TC; Schneider, GE; Vernick, NH; Cagle, JG 2025 Other Linking Intervention and Impact Yes Adult residents of Howard County, Maryland received a community-based advance care planning campaign running from 2017 to 2021, aimed at increasing living will and health care agent documentation in the general adult population. Yes Yes Favorable ACP adoption increased overall by more than 10% since 2016 (p < 0.001) across 6,037 respondents surveyed over three years. Upward trends appeared across all racial groups, but statistically significant increases were found only among White and Hispanic residents (p < 0.001). Increased odds of ACP adoption associated with the campaign were found for residents aged 65 and under, White residents, married individuals, and those with a regular health care provider (e.g. OR 1.35, p < 0.001). The authors concluded that community-based campaigns can increase ACP awareness and adoption, though more work is needed in diverse communities. Palliative Medicine Reports PubMed 10.1177/10966218251362129 https://www.liebertpub.com/doi/10.1177/10966218251362129
The Effects of Advance Care Planning Interventions in the Older Population: A Systematic Review and Meta-Analysis Lin, H; Ko, E; Wu, B; Pei, Y; Ni, P; Zhang, T 2026 Meta Analysis Linking Intervention and Impact Yes Included studies evaluated advance care planning interventions in older populations across Asian and Western cultural contexts. Yes Favorable ACP interventions significantly increased completion of ACP documents, occurrence of ACP and end-of-life care discussions, consistency between preferred and actual end-of-life care, and ACP engagement among older populations, across 32 included studies. Geriatrics & Gerontology International PubMed 10.1111/ggi.70306 https://onlinelibrary.wiley.com/doi/10.1111/ggi.70306
Race-Specific Impact of Telehealth Advance Care Planning on Cost of Dementia: A Cost Prediction Study Reed, PS; Kim, Y; Shen, JJ; Kosaraju, S; Kang, M; Carson, J; Ioanitoaia Chaudhry, I; Kim, S; Jeong, C; Hwang, Y; Yoo, JW 2025 Other Linking Intervention and Impact Yes Primary care providers trained through two Geriatrics Workforce Enhancement Programs delivered advance care planning via telehealth to dual-eligible Medicare/Medicaid patients in an urban safety net system. Yes Dementia Favorable Receiving ACP was associated with lower hospitalization costs of USD 23,928.84 overall. Compared with non-Hispanic Whites, hospitalization costs among Hispanic elders were higher by USD 14,232.40, while costs for non-English speakers and those with increased comorbidities were higher by USD 27,346.60 and USD 26,072.70 respectively. Dementia patients seen by providers trained to offer telehealth ACP realized significant cost savings, with marked differences among those of non-White racial backgrounds. International Journal of Environmental Research and Public Health PubMed 10.3390/ijerph22091399 https://doi.org/10.3390/ijerph22091399
Effect of a Peaceful End-of-Life Care Program on Perceived Good Death in People With Advanced Cancer and Their Family Caregivers Trakoolngamden, B; Monkong, S; Chaiviboontham, S; Satitvipawee, P; Runglodvatana, Y 2025 Other Linking Intervention and Impact Yes Patients and family caregivers received the Peaceful End-of-Life Care Program: a 4-week program of health education, self-care for symptom management, advance care planning, psychosocial support and family involvement, plus standard care; the control group received standard care alone. Yes Cancer Favorable The experimental group showed significant improvement in perceived good death (Good Death Inventory), quality of relationships, and end-of-life care knowledge, with no such improvements in the control group, across 122 enrolled participants. The authors recommended early initiation of the program to optimize benefits. Journal of Hospice & Palliative Nursing PubMed 39804048 10.1097/NJH.0000000000001100 https://pubmed.ncbi.nlm.nih.gov/39804048/
Effect of a multi-component palliative care intervention on goals of care discussions for critical patients in the emergency department Murray, J; Grami, Z; Benson, K; Hritz, C; Lawson, S; Grudzen, CR; Cuthel, A; Southerland, LTF 2025 Other Linking Intervention and Impact Yes Emergency department clinicians received PRIM-ER, a multi-component primary palliative care intervention comprising evidence-based multidisciplinary education, simulation-based workshops on serious illness communication, clinical decision support, and audit and feedback. Yes Neutral The intervention did not change the proportion receiving a goals-of-care conversation in the ED (38.2% vs 40.3%, p = 0.79) across 153 included cases (76 pre-intervention, 77 post-intervention), and only 6.5% had a DNR order before the ED visit. Cancer-related complaints (OR 12.9, 95% CI 4.15–39.92) and respiratory emergencies (OR 3.02) were associated with increased odds of a GOC conversation. Of the 60 GOC conversations that occurred, 76.7% resulted in a change in code status, care plans, hospice, or updated ACP documents. Internal and Emergency Medicine PubMed 40699283 10.1007/s11739-025-04048-5 https://link.springer.com/article/10.1007/s11739-025-04048-5
Exploring the mediating role of social environment in the relationship between built environment and mental health of older adults-evidence from Guangzhou, China Rongrong, Z; Yulu, Y; Yanan, S; Xiong, H; Shaoyang, Z; Jiaxiang, H; Yongwang, C 2026 Other Linking Gap and Impact Yes N/A Yes Mental Health Favorable Park accessibility and distance to the nearest park were significantly positively correlated with older adults' mental health, while greater distance to the nearest public transit station was significantly negatively correlated. Social capital and community safety played significant mediating roles between the built environment and mental health. Among middle- and higher-income older adults, community safety partially mediated the relationship between distance to the nearest public transit station and mental health, and mediating pathways differed significantly by income level. Frontiers in Public Health PubMed 10.3389/fpubh.2026.1706431 https://doi.org/10.3389/fpubh.2026.1706431
Beyond screening: neighborhood-level factors associated with colorectal cancer stage at diagnosis Lal, T; Chakraborty, NN; Koroukian, S; Rose, J; Dong, W; Hoehn, RS 2026 Other Linking Gap and Impact Yes N/A Yes Yes Cancer Favorable Structural factors, rather than screening uptake, were the top predictors of early-stage diagnosis. In multivariable models, uninsurance (β = −0.29) and public transportation dependence (β = −0.31) were associated with lower early-stage diagnosis, while community screening rate was not independently associated. The authors concluded that structural barriers disrupt the screening-to-diagnosis pathway at the community level and emphasized investment in follow-up infrastructure, including patient navigation and transportation. Cancer Causes & Control Google Scholar 41455016 10.1007/s10552-025-02082-4 https://doi.org/10.1007/s10552-025-02082-4
A pilot randomized controlled trial of a transportation assistance program in liver transplant (TAP-LT) candidates Zhou, K; Wong, C; Almanza, J; Chen, A; Kahn, J; Ahearn, A; Terrault, N 2026 RCT Linking Intervention and Impact Yes Transportation assistance program (Lyft rideshares) among at-risk liver transplant candidates (TAP-LT) Favorable At the end of the study, patient satisfaction with medical care, assessed by the RAND PSQ-18, was high in both arms. All 100% of intervention participants reported being more likely to attend medical visits because of the TAP-LT program, and there were no safety concerns. Liver Transpl Siren 41705818 https://doi.org/10.1097/lvt.0000000000000832 https://pubmed.ncbi.nlm.nih.gov/41705818/
Beyond the no-show: A case study highlighting the hidden scope of barriers to radiotherapy adherence in cancer care Biggins, CA; Kirstein, LJ; Reilly, E; Swingle, K; Christensen, K; Marquez, L; Daniels, M 2026 Case Study Linking Gap and Impact Yes N/A Yes Yes Cancer Unfavorable This project reveals an "iceberg problem" where transportation insecurity's true magnitude remains hidden beneath outcome-oriented no-show metrics. The substantial discrepancy between low rates of transportation-related missed appointments (5.3%) and high social work time allocation (14.8%) demonstrates that no-show rates mask significant institutional workload required to maintain treatment adherence. Surgery Siren 41653641 https://doi.org/10.1016/j.surg.2026.110087 https://pubmed.ncbi.nlm.nih.gov/41653641/
Exploring Indoor Home Environment Factors Influencing Fear of Falling: A Systematic Review Parab, KV; Arora, A; Kang, J; Mahajan, HP 2025 Systematic Review Linking Intervention and Impact Yes Included studies intervened on single or multiple indoor home environment factors; most were experimental. Yes Favorable Associations were found between indoor home environment factors and fear of falling across 24 studies, suggesting the importance of home modifications to create a supportive environment that reduces FOF. Because most included studies were experimental and intervened on single or multiple IHE factors, the authors characterized the evidence as reasonably strong. Journal of Applied Gerontology PubMed 10.1177/07334648241286332 https://doi.org/10.1177/07334648241286332
Unmet needs and nursing home placements in Black, Latino, and White people living with dementia Travers Altizer, J; Shenoy, S; Balaji, A; Bergh, M; Raval, A; Jimenez, A 2025 Other Linking Gap and Impact Yes N/A Dementia Favorable Seven distinct themes specific to unmet needs emerged from interviews with people living with dementia, family care partners, nursing home staff and aging policy experts: (1) assistance with activities of daily living and basic home maintenance; (2) resources and services; (3) treatment-related services; (4) socialization; (5) individual preferences; (6) function of the home, including unaddressed home modification needs; and (7) equipped, available and supported family. The authors noted that many nursing home placements are avoidable given that equivalent care is possible in community settings. Alzheimer's & Dementia PubMed 10.1002/alz.70265 https://doi.org/10.1002/alz.70265
A Systematic Review of Home Modifications for Aging in Place in Older Adults Cha, SM 2025 Systematic Review Linking Intervention and Impact Yes Included studies evaluated home modifications supporting aging in place, spanning functional independence, quality of life, caregiving burden and technological advancements. Yes Favorable Thirteen of 20 included studies (65%) confirmed the effectiveness of home modifications in fall prevention, functional independence and cost savings, while seven (35%) highlighted housing accessibility and lifestyle factors. Few studies examined personalized interventions, smart home technologies or long-term adaptability. The author concluded that personalized, technology-driven and long-term adaptable home modifications are needed, and that future research should explore smart home innovations, interdisciplinary approaches and policy implementation feasibility. Healthcare PubMed 10.3390/healthcare13070752 https://doi.org/10.3390/healthcare13070752
Home Modification Outcomes for Adults Aged 50 Years and Over and Their Relatives: A Scoping Review Hutchinson, C; Block, H; Dymmott, A; Gough, C; Laver, K; Walker, R; Xiao, L; George, S 2025 Other Linking Intervention and Impact Yes Included studies evaluated home modifications for community-dwelling adults aged 50 and over and their family carers. Yes Yes Favorable Sixteen outcomes were identified across 38 included articles: 14 positive and two negative. Positive outcomes included reduction in falls and falls risk and enhanced quality of life for community-dwelling adults aged 50 and over and their family carers. OTJR: Occupational Therapy Journal of Research PubMed 10.1177/15394492251361086 https://doi.org/10.1177/15394492251361086
The effect of home modification on quality of life and environmental risk in older adults: a single-group intervention study Akyurek, G; Özata Değerli, MN 2025 Other Linking Intervention and Impact Yes Participants received in-home assessments of environmental risks followed by tailored home modification recommendations. Yes Favorable Environmental risk scores fell significantly across all areas of the home (Z = −4.472, p < 0.001) among 32 community-dwelling older adults (mean age 71.3 ± 6.4). Quality of life improved significantly on both the physical (Z = −3.781, p < 0.001) and mental (Z = −2.096, p = 0.036) components of the SF-12. The authors concluded that low-cost, individualised home modifications can reduce environmental risk and enhance both physical and mental quality of life, supporting ageing in place and the integration of environmental assessment into routine occupational therapy practice. Disability and Rehabilitation: Assistive Technology PubMed 10.1080/17483107.2025.2610356 https://doi.org/10.1080/17483107.2025.2610356
Evaluation of home modifications for individuals with mobility impairments using virtual reality and wearable sensors Luo, Y; Gopinadhan, J; Grimaldi, NS; Lu, X; Ahrentzen, S; Srinivasan, R; Hu, B 2026 Other Linking Intervention and Impact Yes Participants performed two consecutive activities of daily living (relocating a robe and going to the bathroom) in original and redesigned bedrooms simulated in a virtual reality system, with wearable sensors capturing motion and posture. Favorable Participants spent less time and walked a shorter distance in the redesigned bedroom layout than the original, and the redesign improved motion smoothness during daily activities; postures adopted also differed between layouts. The authors concluded that bedroom repurposing improves home accessibility for people with and without mobility issues, by directly connecting the bed with the bathroom and replacing the panel door with a pocket door, and by removing door access to the closet and incorporating it into the bedroom. Disability and Rehabilitation: Assistive Technology PubMed 10.1080/17483107.2025.2555536 https://doi.org/10.1080/17483107.2025.2555536
Examining the effects of home modifications on perceptions of exertion and safety among people with mobility disabilities Goddard, KS; Hall, JP; Greiman, L; Koon, LM; Gray, RC 2025 Other Linking Intervention and Impact Yes Participants recruited from four Centers for Independent Living received the Home Usability Program: a comprehensive assessment followed by consumer-directed, individualized home modifications to improve accessibility, safety and independence. The Home Usability Program intervention decreased exertion among people with mobility disabilities, according to pre-post measures and participant interviews. Decreased exertion produced further benefits including more time for other activities, improved socialization, enhanced independence and the potential to engage in activities outside the home. The intervention also increased safety, which positively affected mental well-being and independence. Disability and Health Journal PubMed 10.1016/j.dhjo.2024.101590 https://doi.org/10.1016/j.dhjo.2024.101590
Housing Conditions Change and its Association with Lung Function, Mobility Limitations, and Depressive Symptoms Among Middle-Aged and Older Chinese Lu, P; Chandola, T; Lou, V 2025 Prosp Cohort Study Linking Gap and Impact Yes N/A Yes Yes Favorable Individuals living in homes with better physical environments, such as barrier-free facilities, and more utilities, such as water and electricity, reported lower risk of mobility limitations and depressive symptoms. Research on Aging PubMed 10.1177/01640275251388875 https://doi.org/10.1177/01640275251388875
Inclusive Practices for Aging in Place: Environmental and Home Modifications for Older Adults Washington, SE; Edwards, E; Fink, A; Radocha, L 2025 Other Linking Intervention and Impact Yes Participants received the Older Adult Home Modification Program: three in-home visits from an occupational therapist, a home modification team and a social worker, combining functional interventions with home modifications for older adults in low-income households. Yes Favorable OAHMP implementation produced significant improvements in self-care activities of daily living and home safety among 65 participants (average age 72, 95.4% women, 87.7% Black or African American, 81.5% living alone), with significant positive relationships between health status and improved independence in ADLs and instrumental ADLs. Participants met or partially met 91% of personal goals, and the average cost of home modifications was significantly lower than national averages. The authors concluded that the program enhances ADL independence and home safety in low-income, diverse communities and supports aging in place through client-centered modifications and interprofessional collaboration. American Journal of Occupational Therapy PubMed 10.5014/ajot.2025.050987 https://doi.org/10.5014/ajot.2025.050987
Priorities for support service needs among individuals with spinal cord injury Nam, HJ; Lee, H; Yoon, JY 2025 Other Linking Gap and Impact Yes N/A Yes Neurologic Disorders Neutral Significant disparities were found between the required and current levels of all 11 key support services for people with spinal cord injury in South Korea. The highest priority services were support for caregiver costs, livelihood security, health management and home modification. Among the 532 community-dwelling participants, 70.1% were male and average age was 49.6 years. Spinal Cord PubMed 10.1038/s41393-025-01079-9 https://doi.org/10.1038/s41393-025-01079-9
Perspectives of Persons With Disabilities Toward Home Adaptations and Assistive Products in Rural Northern Thailand: Comparative Study Kaunnil, A; Munkhetvit, P; Apikomonkon, H; Griffiths, J 2025 Other Linking Intervention and Impact Yes Experienced users had received home adaptations and assistive products in their homes; the comparison group had no such experience. Favorable Most individuals without home adaptations and assistive products were dissatisfied with their living conditions (36/48, 75%) and felt unsafe at home (33/48, 69%), whereas experienced users reported higher satisfaction (21/36, 58%) and safety confidence (25/36, 69%), and 75% (27/36) reported improved participation skills. Significant between-group differences were found for perspectives on home conditions, living environment and assistive products (P < .001), confidence in safety (P < .001), and skills for home engagement (P < .03). Both groups recognized the benefits: 94% (45/48) and 91% (33/36) agreed the adaptations improve daily functioning, and 95% (46/48) and 92% (33/36) agreed they reduce accident risks. Social participation was significantly enhanced (P < .04), though financial constraints were reported as a barrier. Asian/Pacific Island Nursing Journal Google Scholar 41129792 10.2196/79040 https://doi.org/10.2196/79040
Home Healthcare Services and Interventions for Older Adults: An Umbrella Review of Systematic Reviews and Meta-Analyses Al-Hamad, A; Yasin, YM; Metersky, K; Kokorelias, KM; Yasin, L; Afzal, F 2025 Systematic Review Linking Intervention and Impact Yes Included reviews evaluated home healthcare services and interventions for older adults across four categories: integrated and multidisciplinary care; preventive and supportive home visits; technological and digital interventions; and physical, transitional and environmental support. Yes Favorable Many interventions led to improved health outcomes across 20 included reviews encompassing over 3.1 million participants, including enhanced functional ability, reduced hospital readmissions and increased satisfaction. Effectiveness varied depending on intervention type, delivery model and population. Challenges included caregiver burden, digital exclusion and implementation in diverse settings. The authors concluded that home healthcare interventions are promising but require context-sensitive, equitable and scalable models. Journal of Ageing and Longevity Google Scholar 10.3390/jal5030025 https://doi.org/10.3390/jal5030025
Needs assessment for home modification and risk factors for home unintentional injuries in post-total knee arthroplasty patients Tongta, S; Woratanarat, P; Wongsak, S; Phonakhae, R; Arunwilai, N; Woratanarat, T 2025 Other Linking Gap and Impact Yes N/A Favorable Falls within 2 weeks after total knee arthroplasty occurred in 33.57% of 140 patients, most often at the home entrance (29.09%), in the living room (23.64%) and in the bathroom (18.18%). Falls were associated with inefficient grab bars (adjusted OR 3.26, 95% CI 1.37–7.81, P = 0.008) and lighting (adjusted OR 12.83, 95% CI 1.36–121.34, P = 0.026). About 38.5% of patients explicitly needed home modifications. The authors concluded that preoperative home assessment and home modifications should be done to minimize fall risk, particularly in common fall locations. Journal of Patient Safety Google Scholar 39804224 10.1097/PTS.0000000000001313 https://pubmed.ncbi.nlm.nih.gov/39804224/
Strategies for Preventing Falls in the Elderly: Focus on Home Hazard Modification and Multifactorial Interventions Menezes, AS; Jacob, SM; Dsouza, CJ 2025 Systematic Review Linking Intervention and Impact Yes Included randomized controlled trials delivered home hazard modification alone or as part of multifactorial fall-prevention interventions. Yes Favorable Home hazard modification produced a positive outcome in reducing falls compared with multifactorial interventions on both primary and secondary outcome measures across six included randomized controlled trials. Although effective for fall reduction, it did not address other critical aspects such as balance, endurance and physical activity levels. The authors concluded that a multifactorial intervention incorporating home hazard modification alongside other targeted strategies may offer a more comprehensive and effective approach to fall prevention. International Journal of Health Sciences and Research Google Scholar 10.52403/ijhsr.20251007 https://doi.org/10.52403/ijhsr.20251007
Implementation of community-based fall prevention program for Thai older persons: a cluster randomized controlled trial Wandee, P; Jirapongsuwan, A; Powwattana, A; Chansatitporn, N 2026 RCT Linking Intervention and Impact Yes The experimental group received a community-based fall prevention program plus usual care over four months, integrating fall awareness, risk assessment and supportive fall prevention activities; the comparison group received usual care only. Falls were tracked via monthly calendars and interviews at 8 and 16 weeks. Yes Favorable At 16 weeks the experimental group experienced a significantly larger reduction in falls than the comparison group (incidence rate ratio 0.20, 95% CI 0.04–0.92; p = 0.04) across 250 older persons in four Thai villages. Participants also showed significant improvements in fall prevention behaviors, physical performance and environmental modifications. The authors concluded that the program effectively reduced falls and improved safety behaviors, indicating the feasibility and potential impact of community-driven fall prevention in similar settings. Scientific Reports Google Scholar 10.1038/s41598-025-34663-3 https://doi.org/10.1038/s41598-025-34663-3
Becoming More CAPABLE: Preliminary Results of Implementing a Person-Centered Intervention for Aging in Place Toto, P; Giatras, A; Perepezko, K; Blanchflower, M; Fields, B 2025 Other Linking Intervention and Impact Yes Ninety older adults recruited through three home and community-based services agencies received CAPABLE — up to 10 occupational therapy and nursing visits plus $1,300 in low-cost home modifications over five months — to address self-identified functional goals. Yes Favorable Sixty-two of 90 participants (69%) completed CAPABLE, with health decline, death or move to a skilled nursing facility the primary reasons for non-completion. Participants set an average of 4.5 goals (range 1–6), most commonly in bathing, functional mobility and pain. Home modification costs averaged $943 per participant, most commonly grab bars (33%), railings (16%) and lighting (15%). Satisfaction scores were high for number of visits, program length, home modifications and goal attainment. Preliminary outcomes suggested that delivering CAPABLE through an area agency on aging is a feasible and acceptable approach to supporting self-identified aging-in-place goals. Innovation in Aging Google Scholar 10.1093/geroni/igaf122.991 https://doi.org/10.1093/geroni/igaf122.991
Bedroom Air Filtration and Home Blood Pressures of Older Adults Living in a Residential Facility Brook, Robert; Song, Yao; Bard, Robert; Wang, Lu; Klaver, Zachary; Ziemba, Rosemary; Barnes, Geoffrey; Brook, Alec; Keilman, Linda; Morishita, Masako 2026 RCT Linking Intervention and Impact Yes Older adults in a senior residential facility used a bedroom portable air cleaner with a HEPA filter for 4 weeks and a sham unit without a filter for 4 weeks, separated by a 2-week washout. Yes No Neutral Thirty-three participants (74.9 ± 7.7 years) completed the trial. Active filtration reduced bedroom PM2.5 (1.3 ± 1.5 vs 8.3 ± 12.8 µg/m3, p < 0.001) and 24-hour personal exposures (5.1 ± 4.6 vs 12.4 ± 15.6 µg/m3, p < 0.001) versus sham. Average home systolic BP did not differ between active and sham periods (127.0 ± 16.2 vs 126.5 ± 16.0 mm Hg, p = 0.59). Larger body mass index and higher baseline systolic BP, and older age combined with either, showed trends toward modifying benefit. Journal of Clinical Hypertension Google Scholar 10.1111/jch.70251 https://onlinelibrary.wiley.com/doi/10.1111/jch.70251
Personalized Environmental Control Systems (PECS): Systematic review of benefits for thermal comfort, air quality, health, and human performance Khovalyg, Dolaana; Bivolarova, Mariya; Shinoda, Jun; Al-Assaad, Douaa; Vellei, Marika; Bandurski, Karol; Chinazzo, Giorgia; Kazanci, Ongun; Kim, Joyce; Kramer, Tobias 2025 Systematic Review Linking Intervention and Impact Yes Reviewed interventions were personalized environmental control systems (PECS)—building-attached, semi-attached, detached, and wearable—delivering individualized thermal conditions and ventilation. Favorable Building-detached PECS often improved thermal sensation, comfort, and acceptability, and combined systems yielded better ratings. Personalized ventilation enhanced indoor air quality by delivering clean air directly to the breathing zone, reducing contaminant exposure. Research on health effects was limited and mainly short-term and controlled, and evidence on human performance was sparse but promising. Inconsistent performance metrics, limited real-world evaluation, and potential publication bias toward positive results were identified as key challenges. Building and Environment Google Scholar 10.1016/j.buildenv.2025.113541 https://www.sciencedirect.com/science/article/pii/S0360132325010145
Housing conditions and the health and wellbeing impacts of climate change: A scoping review Cartwright, Angela; Khalatbari-Soltani, Saman; Zhang, Ying 2025 Systematic Review Linking Intervention and Impact Yes Reviewed interventions were housing modifications for climate adaptation, including air conditioning, ventilation, window shading, and insulation. Favorable Heat-health impacts were the most common focus among included articles. Housing conditions that improved heat-health outcomes included air conditioning, ventilation, and window shading, and multifaceted housing adaptations were better supported than single fixes. Ventilation was a priority for improving indoor air quality, while inappropriate insulation and excessive air tightness increased indoor heat and reduced indoor air quality. Environmental Research Google Scholar 39855413 10.1016/j.envres.2025.120846 https://pubmed.ncbi.nlm.nih.gov/39855413/
An analysis of trends in the burden of ischemic stroke caused by air pollution in China between 1990 and 2021 Yu, Zhengfeng; Zhang, Xiuyun; Fu, Xiaomei; Jia, Xuemin; Ju, Mingyan; Zhang, Yuxuan; Li, Yuying; Yin, Ying; Liu, Fanjie 2025 Other Linking Gap and Impact Yes N/A Yes Yes Stroke Favorable Between 1990 and 2021, age-standardized mortality and DALY rates for ischemic stroke attributed to air pollution declined in China, though more slowly among men than women and with a higher burden in elderly males. Epidemiological transitions, including improved healthcare and lifestyle changes, drove most of the reduction. Over the next 15 years, rates for women were projected to continue declining, while male mortality rates were projected to rise and male DALY rates to increase before stabilizing. BMC Public Health Google Scholar 40296073 10.1186/s12889-025-22287-1 https://pubmed.ncbi.nlm.nih.gov/40296073/
Ventilation and air conditioning systems are a source of antibiotic-resistant bacteria-A review Gorlach, Jakub; Gazda, Dawid; Trusz, Agnieszka; Walaszczyk, Juliusz; Szczęśniak, Sylwia; Piekarska, Katarzyna 2025 Other Linking Gap and Impact Yes N/A Favorable The review identified 96 bacterial and 61 fungal species, some endemic to HVAC systems or AC units and some occurring in both. Specific taxa such as Alternaria spp. and Cladosporium spp. in ventilation systems carried allergenic and pathogenic potential. Diverse microbes thrived in HVAC systems and required regular maintenance; cleaning reduced health risks and air purifiers cut bacterial contamination. Research gaps remained in moderate climates. Building and Environment Google Scholar 10.1016/j.buildenv.2025.112583 https://www.sciencedirect.com/science/article/abs/pii/S0360132325000654
Longitudinal associations between air pollution and incident dementia as mediated by MRI-measured brain volumes in the UK Biobank Thompson, Rhiannon; Tong, Xinning; Shen, Xueyi; Ran, Jinjun; Sun, Shengzhi; Yao, Xiaoxin Iris; Shen, Chen 2025 Prosp Cohort Study Linking Gap and Impact Yes N/A Yes Yes Dementia Favorable Small but significant mediating effects (2%-8% of relationships mediated) were observed between PM2.5abs exposure and dementia risk via reduced total brain volume, NOx and Alzheimer's disease risk via reduced peripheral cortical grey matter, PM2.5abs and vascular dementia risk via reduced peripheral cortical grey matter, PM2.5abs and other dementia risk via reduced total grey matter, and PM10 and other dementia risk via reduced total grey matter. Greenspace and noise were not associated with dementia outcomes in the brain imaging subset. Environment International Journal Google Scholar 39732110 10.1016/j.envint.2024.109219 https://pubmed.ncbi.nlm.nih.gov/39732110/
The association of air pollution with new‐onset epilepsy Antaya, Tresah; Le, Britney; Oiamo, Tor; Wilk, Piotr; Speechley, Kathy; Burneo, Jorge 2025 Other Linking Gap and Impact Yes N/A Yes Yes Neurologic Disorders Favorable The study included 24,761 cases and 118,692 controls. Median (IQR) concentrations were 7.9 (1.3) μg/m3 for PM2.5, 9.6 (9.2) ppb for NO2, and 42.7 (5.4) ppb for O3. In individual pollutant models, epilepsy was significantly associated with PM2.5 (IRR = 1.055, 95% CI 1.034-1.076), NO2 (IRR = 0.938, 95% CI 0.903-0.974), and O3 (IRR = 1.096, 95% CI 1.074-1.119). In the multi-pollutant model, associations remained for NO2 (IRR = 0.928) and O3 (IRR = 1.090). The NO2 association was negative overall but positive among individuals 65 and older. Epilepsia Google Scholar 40152805 10.1111/epi.18389 https://pubmed.ncbi.nlm.nih.gov/40152805/
The interactive effect of extreme weather events and PM2. 5 on respiratory health among the elderly: a case-crossover study in a high-altitude city Ning, Zhenxu; Ma, Yanjun; He, Shuzhen; Li, Genshan; Xiao, Ting; Ma, Chunguang; Wu, Jing 2025 Other Linking Gap and Impact Yes N/A Yes No Chronic Lung Disorders Favorable Heat wave and cold spell exposure were significantly associated with outpatient visits for respiratory disease among the elderly, with odds ratios of 1.10 (95% CI 1.06, 1.15) and 1.16 (95% CI 1.13, 1.20). A synergistic effect between cold spell and PM2.5 was observed, particularly among females and those aged 80 and older. Combined exposure to cold spell and elevated PM2.5 contributed up to 0.18 (95% CI 0.17, 0.27) of respiratory outpatient visits. International Journal of Biometeorology Google Scholar doi.org/10.1007/s00484-024-02811-5 https://link.springer.com/article/10.1007/s00484-024-02811-5
Air pollution is associated with increased risk of venous thromboembolism: the Multi-Ethnic Study of Atherosclerosis Lutsey, Pamela; Misialek, Jeffrey; Young, Michael; Berman, Jesse; Leiser, Claire; Pope, Zachary; Cushman, Mary; Folsom, Aaron; Kaufman, Joel 2025 Prosp Cohort Study Linking Gap and Impact Yes N/A Yes Yes Hematologic Disorders Favorable A total of 248 VTE events accrued over a median follow-up of 16.7 years. After adjustment for baseline demographics, health behaviors, and body mass index, the hazard ratio for incident VTE was 1.39 (1.04-1.86) per 3.6 μg/m3 higher PM2.5, 2.74 (1.57-4.77) per 13.3 ppb higher NO2, and 2.21 (1.42-3.44) per 30 ppb higher NOx. O3 was not related. Blood Google Scholar 10.1182/blood.2024026399 https://ashpublications.org/blood/article/145/10/1089/534404/Air-pollution-is-associated-with-increased-risk-of
The impact of extreme temperatures on emergency department visits: A systematic review of heatwaves, cold waves, and daily temperature variations PoshtMashhadi, Ali; Maghsoodi, Abtin Ijadi; Wood, Lincoln 2025 Systematic Review Linking Gap and Impact Yes N/A Yes Yes Chronic Lung Disorders Cardiovascular Disorders Favorable Heatwaves were consistently associated with increased ED admissions, including orthopaedic trauma and exacerbations of chronic illnesses, and with increased ambulance demand mainly for trauma. Cold waves were linked primarily to respiratory and cardiovascular presentations, often with delayed effects, and raised ED visits for fall injuries. Air pollution and urban heat worsened temperature-related risks. Older adults, those with pre-existing conditions, and socioeconomically disadvantaged populations faced disproportionately severe consequences. Science of The Total Environment Google Scholar 10.1016/j.scitotenv.2025.178869 https://www.sciencedirect.com/science/article/pii/S0048969725005042
Effects of particulate air pollution on BPDE-DNA adducts, telomere length, and mitochondrial DNA copy number in human exhaled breath condensate and BEAS-2B cells Pedklang, Naruporn; Navasumrit, Panida; Chompoobut, Chalida; Promvijit, Jeerawan; Hunsonti, Potchanee; Ruchirawat, Mathuros 2025 Other Linking Gap and Impact Yes N/A Favorable Among 60 healthy subjects, residents of high-traffic-congested areas were exposed to higher concentrations of PM2.5 (1.66-fold, p < 0.01), ultrafine particles (1.79-fold, p < 0.01), PM2.5-PAHs (1.50-fold, p < 0.01), and UFP-PAHs (1.35-fold, p < 0.05) than those in low-traffic areas. The high-traffic group had significantly increased BPDE-DNA adducts (1.40-fold, p < 0.05), telomere shortening (1.24-fold, p < 0.05), and lower mtDNA copy number (1.38-fold, p < 0.05) in exhaled breath condensate. In vitro treatment of BEAS-2B cells reproduced these findings, mediated in part by decreased hTERT and SIRT1 transcript levels. International Journal of Hygiene and Environmental Health Google Scholar 39561502 10.1016/j.ijheh.2024.114488 https://pubmed.ncbi.nlm.nih.gov/39561502/
Ambient particulate matter and frequency of outpatient visits for chronic rhinosinusitis in the United States Yang, Hong-Ho; Grimm, David; Velasquez, Esther; Hwang, Peter 2025 Other Linking Gap and Impact Yes N/A Favorable Across 3,933 observations (CBSA × year combinations) encompassing approximately 4 billion visits, median CRS outpatient visits were 164 (IQR 110-267). Mean PM2.5 was 8.9 µg/m3 (SD 2.6) and mean PM10 was 20.2 µg/m3 (SD 7.2). Adjusting for patient demographics and respiratory comorbidities, each µg/m3 rise in PM2.5 independently predicted a 10% increase in CRS outpatient visits (aIRR 1.10, 95% CI 1.08-1.13) and each µg/m3 rise in PM10 predicted a 3% increase (aIRR 1.03, 95% CI 1.02-1.04). International Forum of Allergy and Rhinology Google Scholar 10.1002/alr.23477 https://onlinelibrary.wiley.com/doi/10.1002/alr.23477
Urban heat island impacts on mental health in middle-aged and older adults Bao, Yujia; Li, Yongxuan; Gu, Jiawei; Shen, Chen; Zhang, Yuzheng; Deng, Xiaobei; Han, Lefei; Ran, Jinjun 2025 Prosp Cohort Study Linking Gap and Impact Yes N/A Yes Yes Mental Health Favorable Summer urban heat island (UHI) intensity was significantly associated with elevated risks of psychiatric disorders. Hazard ratios per standard deviation of UHI intensity were 1.04 (95% CI 1.03-1.05) for mental disorders, 1.12 (1.11-1.14) for substance use disorder, 1.08 (1.06-1.10) for depressive disorder, and 1.06 (1.04-1.08) for anxiety disorder. Females and individuals with hypertension or coronary artery disease were more vulnerable. Detrimental effects on psychiatric symptoms and white matter microstructure were also observed. Environment International Google Scholar 40286554 10.1016/j.envint.2025.109470 https://pubmed.ncbi.nlm.nih.gov/40286554/
Damp and mould: improving the health and homes of children with asthma through NHS and local authority collaboration Hannant, Katherine 2025 Case Study Linking Intervention and Impact Yes Children and young people with asthma received targeted asthma interventions, personalised education, and environmental remediation of damp and mould through community-based clinics, roadshows, and family hubs. No Yes Chronic Lung Disorders Favorable The initiative improved asthma control for many children and young people and highlighted the role of children's nurses in delivering interdisciplinary care, advocating for systemic change, and supporting vulnerable families. No quantitative effect estimates were reported. Nursing Children and Young People Google Scholar 40785413 10.7748/ncyp.2025.e1552 https://pubmed.ncbi.nlm.nih.gov/40785413/
Structural Ableism, Health, and Functioning among People with Disabilities: An Extension of the Social Determinants of Health Framework Brown, RL 2025 Other Linking Gap and Impact Yes N/A Yes Favorable Structural ableism operated through distinct pathways for each outcome. State-level gaps by disability status in income, health insurance coverage and public transportation access significantly predicted worse self-rated health, while health insurance and housing accessibility gaps were the strongest predictors of functional limitation. The findings supported treating transportation and housing access disparities as structural determinants of health and functioning among people with disabilities. Journal of Health and Social Behavior PubMed 10.1177/00221465251379456 https://doi.org/10.1177/00221465251379456
Home, but Homebound After Traumatic Brain Injury: Risk Factors and Associations With Nursing Home Entry and Death Kumar, RG; Pomeroy, ML; Ornstein, KA; Juengst, SB; Wagner, AK; Reckrey, JM; Lercher, K; Dreer, LE; Evans, E; de Souza, NL; Dams-O'Connor, K 2025 Prosp Cohort Study Linking Gap and Impact Yes N/A Yes Yes Neurologic Disorders Favorable Homebound status at 1 year post-injury affected 14.2% of participants, including 2% who never left home. Dependence on others or on special services for transportation, older age, less than a bachelor's degree, Medicaid insurance, residence in the Northeast or Midwest, unemployment or retirement, and needing assistance with locomotion, bladder management and social interaction were each associated with being homebound. After adjustment, homebound status carried a 1.69-times greater risk of 5-year mortality (95% CI 1.35–2.11) and a nonsignificant trend toward nursing home entry by 5 years (RR 1.90, 95% CI 0.94–3.87); mortality associations were consistent above and below age 65. The authors identified accessible public transportation and home care as modifiable targets for referral and policy intervention. Archives of Physical Medicine and Rehabilitation PubMed 39374687 10.1016/j.apmr.2024.09.012 https://doi.org/10.1016/j.apmr.2024.09.012
Social Risk Factors and Kidney Transplant Waitlisting Among Patients Receiving Dialysis: A National Cohort Study Hamdan, H; Shieu, M; Li, NC; Babroudi, S; Harford, A; Majchrzak, K; Johnson, D; Lacson, E Jr; Weiner, DE 2026 Other Linking Gap and Impact Yes N/A Yes Yes End-Stage Renal Disease Favorable More than 10% of patients in the national dialysis cohort reported one or more social risk factor, and a higher burden of social risk factors was associated with increased odds of being neither actively waitlisted nor transplanted. The authors concluded that addressing social risk factors, including transportation barriers, may improve access to kidney transplant. Kidney Medicine PubMed 10.1016/j.xkme.2026.101294 https://www.kidneymedicinejournal.org/article/S2590-0595(26)00055-5/fulltext
Effect of indoor air quality on potential risk of obstructive sleep apnea: results from Korea National Health and Nutrition Examination Survey Kim, Sungroul; Gurmu, Birhan Legese; Kim, Mingi; Song, Chiyou; Lee, Mee-Ri; Lim, Chris Chaeha; Rule, Ana; Yang, Kwang Ik 2025 Prosp Cohort Study Linking Gap and Impact Yes N/A Favorable Each unit increase in indoor formaldehyde (HCHO) exposure raised OSA risk 1.02-fold (1.00-1.02) in men, after controlling for socioeconomic and behavioural factors, other common indoor pollutants (CO2, PM2.5, toluene), and outdoor PM2.5. No significant association was found in women. BMC Public Health PubMed 40197163 10.1186/s12889-025-22127-2 https://pubmed.ncbi.nlm.nih.gov/40197163/
Dissecting the connection between volatile organic compounds and cardiovascular disease: immune cell-mediated mechanism Cao, Qi; Liu, Jiajing; Lu, Daiyao; Song, Junhuai; Yu, Qiming; Wen, Jinkun; Zheng, Bin 2025 Other Linking Gap and Impact Yes N/A Cardiovascular Disorders Favorable Urinary DHBMA, HPMMA, and ATCA were significantly positively associated with risk of angina and coronary heart disease across all three models. The strongest associations appeared among normal-weight adults, moderately active individuals, both low- and high-income groups, and current drinkers. Monocyte-related pathways mediated 13.1%-112.4% of these associations, and transcriptomic profiling showed enrichment of NF-κB and AGE-RAGE signaling. Exotoxicology and Environmental Safety PubMed 40359856 10.1016/j.ecoenv.2025.118297 https://pubmed.ncbi.nlm.nih.gov/40359856/
Association between indoor ventilation frequency and low muscle mass among older adults in China: a national cross-sectional research Wei, Jun; Lin, Yun; Xian, Xiaobing; Wang, Zhigang; Tang, Jing 2025 Other Linking Intervention and Impact Yes N/A Yes No Favorable Participants with intermediate indoor ventilation frequency (OR 0.805; 95% CI 0.669-0.969) and high frequency (OR 0.818; 95% CI 0.684-0.979) were 19.5% and 18.2% less likely to have low muscle mass than those with low frequency. In spring, the probability of low muscle mass was 25.3% and 23.3% lower in the middle- and high-frequency groups. Associations remained significant across demographic, behavioural, and comorbidity subgroups. Scientific Reports PubMed 10.1038/s41598-025-94865-7 https://www.nature.com/articles/s41598-025-94865-7
Effects of Daikin air purifiers on asthma control and pulmonary function: A multicenter, single-arm, observational pilot study Hamada, Satoshi; Sato, Susumu; Hori, Shota; Yu, Shiqi; Sunadome, Hironobu; Murase, Kimihiko; Hirai, Toyohiro 2025 Other Linking Intervention and Impact Yes Patients with asthma used Daikin air purifiers in their homes for one month, with asthma control and pulmonary function assessed before and after. Yes Yes Chronic Lung Disorders Favorable Eighteen patients participated (median age 64 years, 66.7% female). Median PM2.5 decreased from 4.6 to 1.4 μg/m3 after air purifier use (p = 0.00042) and FEV1 increased from 2.0 to 2.1 L (p = 0.041), a median change of 40 mL. Patients whose FEV1 improved had a higher frequency of allergen sensitization than those without improvement (75.0% vs 16.7%, p = 0.019).  Respiratory Investigation PubMed 40902284 10.1016/j.resinv.2025.08.008 https://pubmed.ncbi.nlm.nih.gov/40902284/
Emission characteristics of indoor HONO from residential natural gas cooking stoves in a household in Kunming, China Wu, Hailin; Ran, Haiyan; Dong, Shijing; Li, Lingling; Liu, Jiangping; Fan, Wenxuan; Lu, Dawei; Zhang, Jingwei; An, Junling 2025 Other Linking Intervention and Impact Yes Three mitigation measures were evaluated in a household kitchen: alkaline cleaning of surfaces, replacement of gas stoves with induction cookers, and range hood operation. Favorable Natural gas stove combustion yielded a HONO/NOx ratio of 5.8 ± 1.5% and a HONO/NG emission factor of 55.6 ± 13.8 mg m⁻³. A few minutes of cooking elevated HONO above 100 ppb and NOx above 1000 ppb. Estimated 2023 Kunming HONO emissions were 17.9 ± 4.4 tons, with urban intensities comparable to traffic sources. Among mitigation measures, alkaline cleaning reduced HONO 30-60%, induction cookers 100%, and range hoods over 90%. Journal of Hazardous Materials PubMed 10.1016/j.jhazmat.2025.138661 https://www.sciencedirect.com/science/article/abs/pii/S0304389425015778
Assessment of pulmonary toxicity in mice to evaluate human health risks from indoor airborne microorganisms Song, Mi-Kyung; Kim, Jun Woo; Kim, Dong Im; Park, Yongsung; Yoon, Wonsuck; Lee, Kyuhong 2025 Other Linking Gap and Impact Yes N/A Favorable All exposure groups showed increased inflammatory cells and cytokines in broncho-alveolar lavage fluid, with histological lung injury including inflammatory cell infiltration and mucous cell hyperplasia. The human-equivalent threshold derived from the mouse benchmark dose 10 indicated that humans may be exposed to indoor fungi at levels capable of causing disease-associated inflammatory lung injury. Journal of Hazardous Materials PubMed 10.1016/j.jhazmat.2025.138884 https://www.sciencedirect.com/science/article/pii/S030438942501800X
The combined impacts of indoor temperature and total volatile organic compounds on cognitive performance of university students: A controlled exposure study Zhao, Zeyu; Bagkeris, Emmanouil; Mumovic, Dejan 2025 Other Linking Gap and Impact Yes N/A No Yes Favorable Temperature significantly affected task accuracy while TVOC levels did not, and neither affected reaction speed. No interaction between temperature and TVOC was found. Within-group tests showed significant accuracy losses in six of ten tasks at 28 °C under 1000 μg/m3 TVOC, with average task error increasing 5.2%. Higher temperatures worsened perceived air quality, and eye irritation and fatigue developed during exposure. Science of The Total Environment PubMed 39922010 10.1016/j.scitotenv.2025.178652 https://pubmed.ncbi.nlm.nih.gov/39922010/
Chronic fatigue syndrome induced by environmental toxic exposure: Effects of polyhexamethyleneguanidine phosphate exposure on mitochondrial function and neural health Yang, Hyo-Seon; Lee, Jin-Seok; Kang, Mi-hyun; Song, Mi-kyung; Kang, Ji-Yun; Kim, Hyung Doo; Kim, Hwan-Cheol; Leem, Jong-Han; Son, Chang-Gue; Lee, Kyuhong 2026 Other Linking Gap and Impact Yes N/A Favorable PBMCs from patients with HD-CFS showed significantly increased mitochondrial abnormalities. In mice, PHMG-p exposure caused mitochondrial abnormalities, decreased OXPHOS complex expression, and downregulated genes related to mitochondrial membrane potential. Neurological assessment revealed glymphatic dysfunction, blood-brain barrier disruption, and reduced OXPHOS complex expression in the hypothalamus. Environmental Research PubMed 10.1016/j.envres.2026.123874 https://www.sciencedirect.com/science/article/abs/pii/S0013935126002021
Effects of Exposure of PHMG-p, a Humidifier Disinfectant Component, on Eye Dryness: A Study on a Rat Model Based on (1)H-NMR Metabolomics Lee, Jung Dae; Kim, Hyang Yeon; Oh, Soo Bean; Goo, Hyeyoon; Cho, Kyong Jin; Hwang, Gi-Wook; Kim, Suhkmann; Kim, Kyu-Bong 2025 Other Linking Gap and Impact Yes N/A Favorable PHMG-p exposure exacerbated dry eye disease symptoms, significantly reducing tear volume, shortening tear break-up time, and increasing corneal damage relative to controls. Metabolomic profiling identified altered glutamate, glycine, citrate, and succinate metabolism, which correlated with increased IL-1β, IL-6, and TNF-α in corneal and lacrimal gland tissues. International Journal of Molecular Science PubMed 40943576 https://doi.org/10.3390/ijms26178660 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12429713/
Optimization of energy-efficient multi-pollutant air purification for healthy residential buildings Gao, Dalong; Zhuang, Wenbin; Liu, Wei; Liu, Zhijian; Ren, Jiawei; Zhang, Nan 2025 Other Linking Intervention and Impact Yes Air purifier control scenarios with differing PM2.5 and benzene concentration thresholds were simulated year-round in Beijing residential buildings. Favorable PM2.5 was the dominant indoor air pollutant, and targeting PM2.5 maximized the reduction in disease burden. Scenario P1 (1-5 μg/m3 threshold) reduced annual average concentrations across six pollutants by 84.5% and associated disease burdens by 36.7%, and holding indoor PM2.5 below 5 μg/m3 avoided 166.2 thousand DALYs. The most cost-effective scenario for Beijing, P4 + B1, avoided 108.9 thousand DALYs, a rate of 873.4 per 100,000. Science of The Total Environment Google Scholar 10.1016/j.scitotenv.2025.180056 https://doi.org/10.1016/j.scitotenv.2025.180056
Effect of portable air filtration systems among female residents of old age home in northern India with hazardous air quality Ahuja, Aman; Kumar, Ashwani; Rulia, Rahul; Bhardwaj, Rashmi; Arya, Geetika; Surapaneni, Vineela; Raj, Vishal; Mohankumar, Jyothi Geetha; Chougale, Samruddhi; Chaudhry, Dhruva 2025 Other Linking Intervention and Impact Yes Female residents of an old age home used portable HEPA air filtration systems in their bedrooms for 2 weeks, then sham units without filters for 2 weeks. Yes Yes Favorable Twenty-nine subjects (mean age 65.83 ± 6.4 years) were analysed. Baseline PM2.5 was in the hazardous category (440.38 ± 44.3 μg/m3), fell to 131.0 ± 19.2 μg/m3 with active filtration, and returned to 414.2 ± 32.2 μg/m3 during sham use. Systolic blood pressure dropped after installation (p < 0.001) while diastolic fell non-significantly (p = 0.14). CRP, 8-oxo-DG, and pulse wave velocity followed the same pattern (p < 0.001). Physiological Reports Google Scholar 10.14814/phy2.70475 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12320120/
Impact of school air quality on children's health and academic performance Fussell, Julia; Giao, Maria Salomé; Rivas, Ioar 2025 Other Linking Gap and Impact Yes N/A No Yes Chronic Lung Disorders Favorable Lung function (FVC, FEV1, FEF25-75) in 617 Chinese school children trended inversely with ambient air pollution near schools, and was worst among children exposed to both high pollutant concentrations and secondhand smoke. Vanadium concentration in classroom dust from 11 Vilnius primary schools correlated significantly with annual incidence of physician-diagnosed acute upper respiratory infections. Reported impacts on children included reduced lung function, asthma, respiratory infections, neurodevelopmental disorders, behavioural issues, and increased obesity risk. Frontiers in Public Health Google Scholar 10.3389/fpubh.2025.1707742 https://www.frontiersin.org/journals/public-health/articles/10.3389/fpubh.2025.1707742/full
Associations of air cleaning interventions in primary school classrooms with indoor environmental quality and perceived symptoms Juntunen, Miina; Täubel, Martin; Yli-Tuomi, Tarja; Taimisto, Pekka; Siponen, Taina; Jalkanen, Kaisa; Valkonen, Maria; Lanki, Timo; Mikkonen, Santtu; Stranger, Marianne 2025 Other Linking Intervention and Impact Yes Portable air cleaners with EPA or HEPA and activated carbon filters were operated in 27 occupied primary school classrooms, in both regular and sham (no filter) mode. No Yes Neutral Air cleaner operation reduced average TVOC concentrations by 52.9% and the PM2.5 indoor/outdoor ratio by 24.8%, and reduced fungal richness and diversity by 25.8% and 8.2%. Microbial levels were otherwise generally unaffected. Pupils reported small reductions in upper and lower respiratory and other symptoms during operation (4.7-7.5%), but similar reductions occurred during sham operation (6.1-8.7%), indicating a likely placebo effect. Building and Environment Google Scholar 10.1016/j.buildenv.2025.112980 https://www.sciencedirect.com/science/article/pii/S0360132325004615
Clearing The Air: The Role Of Advanced HVAC And HEPA Filtration In Mitigating Respiratory Pathogens Alshehri, Nawaf Saeed Salem; Al Mustaneer, Hamad Saleh Nasser; Alanazi, Fatimah Kuways; Al-Otaibi, Faisal Kadimis Dahimish; Alotaibi, Bejad Sattam Sulttan; Al-Otaibi, Bandar Muthaib Saleh; Al-Otaibi, Abdullah Saad Muslim; Alruwaili, Olayan Eid Olayan; Alasmari, Ali Abdullah Mohammed; Alsenani, Sami Ayed 2025 Other Linking Intervention and Impact Yes Reviewed interventions were advanced HVAC systems integrated with HEPA filtration (H13-H14, >99.95% efficiency at 0.3 μm), deployed across hospitals, schools, and low-resource settings. Favorable HEPA filtration achieved 2-5 log10 reductions in viral aerosols, clearing over 99.97% of SARS-CoV-2 after seven air volumes. HVAC-HEPA combinations delivering 6-12 air changes per hour reduced infection risk by 40-90%, outperforming standard ventilation. Real-world deployments lowered healthcare-associated infections and bioaerosols by 70-90% in ICUs and wards. The Review of Diabetic Studies Google Scholar 10.70082/erbnhr88 https://diabeticstudies.org/index.php/RDS/article/view/1498
Enhancing indoor air quality and cardiopulmonary health in patients with asthma by photocatalytic oxidation and filters air cleaner Zhang, Jia Lin; Liao, Guan-Yu; Lin, Hong-Yi; Xie, Jie-An; Li, Wan-Chen; Chen, Huang-Chi; Wu, Da Wei; Juan, Huai-Lei; Kuo, Jia-Yu; Chen, Pei-Shih 2025 RCT Linking Intervention and Impact Yes Households of patients with asthma received photocatalytic oxidation (PCO) air cleaners, and PCO combined with filters, in a crossover sequence. Chronic Lung Disorders Neutral TVOC and SO2 fell significantly after the PCO intervention, but FVC% and FEV3% also declined significantly and FeNO rose after 13 days. PCO plus filters significantly reduced PM1, PM2.5, PM4, PM10, total suspended particulates, ultrafine particles, airborne bacteria, fungi, endotoxin, mites, TVOC, NO2, and SO2, with a marginal reduction in carbon monoxide. Indoor carbon dioxide increased significantly under both interventions. FVC% and FEV1% increased marginally 7 days after PCO plus filters. Journal of Hazardous Materials Google Scholar 39581037 10.1016/j.jhazmat.2024.136573 https://pubmed.ncbi.nlm.nih.gov/39581037/
How air pollution fuels respiratory infections in children: current insights Esposito, Susanna; Fainardi, Valentina; Titolo, Annachiara; Lazzara, Angela; Menzella, Marialaura; Campana, Beatrice; Argentiero, Alberto; Principi, Nicola 2025 Other Linking Gap and Impact Yes N/A No Yes Chronic Lung Disorders Favorable Pollution significantly increased the risk of upper and lower respiratory tract infections in children, with infants and young children most vulnerable. Proposed mechanisms included oxidative stress, inflammatory responses, immune deregulation, and genetic alterations. Prenatal exposure altered respiratory tract development and increased risk of lower respiratory tract infection and acute otitis media early in life, while postnatal exposure caused severe and recurrent infections leading to frequent hospitalisations. Available data did not permit precise definition of the magnitude of risk or the role of specific pollutants. Frontiers in Public Health Google Scholar 10.3389/fpubh.2025.1567206 https://www.frontiersin.org/journals/public-health/articles/10.3389/fpubh.2025.1567206/full
How Indoor Air Quality Affects Sleep in Older Adults: Evidence from the 2018 CLHLS Xu, Cai; Lee, Yen-Han 2025 Other Linking Intervention and Impact Yes N/A Yes No Favorable Among 9,902 adults aged 65 and older, three ventilation classes were identified: Moderate with Summer-Selective Ventilation (11.2%), Strong Year-Round Ventilation (70.3%), and Minimal Ventilation (18.7%). Older adults with Strong Year-Round Ventilation (OR 1.16, p < 0.01) and Moderate with Summer-Selective Ventilation (OR 1.19, p < 0.05) had significantly better sleep quality. Adults with Strong Year-Round Ventilation slept 0.30 hours longer per day (p < 0.001), and urban older adults with Moderate with Summer-Selective Ventilation slept 0.46 hours longer (p < 0.01). Innovation in Aging Google Scholar 10.1093/geroni/igaf122.247 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12759496/
Association between fine particulate matter (PM2. 5) and atopic dermatitis—a systematic review Weslock, Noah; Drew, Delaney; Palanichami, Deepak; La, Anthony; Shoctor, Hannah; Amir, Alkhafaji; Ramdass, Prakash; Mitchell, Kerry 2026 Systematic Review Linking Gap and Impact Yes N/A Yes Yes Favorable Eleven studies met the inclusion criteria. All found a statistically significant increase in atopic dermatitis in some subgroups, though not all found significance in the general population. Outcomes measured included clinic and hospital visits and worsening AD symptoms. Males, children, and the elderly were the most affected subgroups in most studies. Discover Public Health Google Scholar 10.1186/s12982-025-00502-z https://link.springer.com/article/10.1186/s12982-025-00502-z
Asthma and the Home Environment: Linking Population Surveillance With Targeted Interventions in Adults Obeng, Alexander Boakye 2025 Other Linking Intervention and Impact No Thirty adults with asthma received HEPA air purifiers combined with asthma education, with indoor PM2.5 and tVOC concentrations and asthma outcomes measured for 15 days before and after installation. No Yes Chronic Lung Disorders Favorable In the surveillance study, increased asthma morbidity was associated with current smoking, lack of bathroom or kitchen ventilation, and absence of air purifier use, while homes without mold, rodents, or furry pets showed protective associations. In the intervention study, indoor PM2.5 fell significantly after installation, alongside improvements in asthma control and quality of life. N/A Google Scholar N/A https://oaktrust.library.tamu.edu/items/2431691f-2b50-44eb-8311-5095519b1db3
The Effects of Air Pollution with Particulate Matter on Human Health Predescu, Elena-Denisa; Rusănescu, Carmen Otilia; Istrate, Irina Aura; Frîncu, Roxana-Elena; Bălănescu, Sabrina Maria 2025 Other Linking Gap and Impact Yes N/A Favorable The review synthesised findings on PM origin, including traffic, industrial emissions, construction activities, and natural processes such as wildfires and volcanic eruptions. It identified relationships between particle size and chemical composition, and reported respiratory and cardiovascular health effects of PM exposure. Scientific Papers. Series E. Land Reclamation, Earth Observation & Surveying, Environmental Engineering Google Scholar N/A https://www.landreclamationjournal.usamv.ro/index.php/scientific-papers/current?id=802
Food Insecurity Interventions to Improve Blood Pressure Berkowitz, Seth A.; Ammerman, Alice S.; Knoepp, Patricia; et al. 2025 RCT Linking Intervention and Impact Yes Comparison of different intervention elements: type of food resources provided, whether to offer lifestyle counseling, and intervention duration. Food resources included healthy food subsidy redeemable at grocery stores vs biweekly healthy food box home delivery. The lifestyle intervention included either no intervention or offering telephone-based lifestyle counseling. The intervention duration included 6 months vs 12 months. Neutral A food subsidy produced better blood pressure control than a delivered food box. Offering lifestyle counseling and a longer benefit duration did not produce better blood pressure outcomes. JAMA Intern Med Siren 10.1001/jamainternmed.2025.5287 https://jamanetwork.com/journals/jamainternalmedicine/fullarticle/2840193
Healthy Food Voucher Programs: Global Evidence on Structure, Implementation, and Nutrition-Related Outcomes Lara-Arevalo, Jonathan; Corvalan, Camila; Pemjean, Isabel; Montes de Oca, Daniela; Ng, Shu Wen; Smith Taillie, Lindsey 2025 Systematic Review Linking Intervention and Impact Yes Incentive programs that provide voucher benefits for healthy foods. Neutral Mixed results were found regarding diet quality indicators, physical health outcomes, and mental health. Advances in Nutrition Siren https://doi.org/10.1016/j.advnut.2025.100530 Healthy Food Voucher Programs: Global Evidence on Structure, Implementation, and Nutrition-Related Outcomes - ScienceDirect
Health outcomes of produce prescription programs associated with Gus Schumacher Nutrition Incentive program funding Byker Shanks, Carmen; Park, Michelle S; Yaroch, Amy L; Short, Eliza; Seligman, Hilary K 2025 Systematic Review Linking Intervention and Impact Yes The US Department of Agriculture's Gus Schumacher Nutrition Incentive Program (GusNIP) funds produce prescription (PPR) programs that allow healthcare to support patients in accessing fruits and vegetables. Unfavorable Fewer than half of the studies examining clinical values showed an association between PPR participation and improved health outcomes (for example, three of eight studies measuring weight or body mass index showed a statistically significant reduction, as well as two of the six studies measuring glycosylated hemoglobin). Annual Review of Nutrition Siren 40354556 10.1146/annurev-nutr-111124-092627 https://pubmed.ncbi.nlm.nih.gov/40354556/
Food is Medicine: The effectiveness of Delaware's feeding families program in managing chronic conditions Oluwadero, John; De Leon, Lydia; Falgowski, Megan; Holman, Eunice; Kennedy, Nicole; Norris-Bent, Maggie; Patosky, Heather; Richardson, Ruthann; Seibold, Mia; Tracy, Tara; Werner, Megan; VanHorne, Samuel; Karpyn, Allison 2025 Other Linking Intervention and Impact Yes The FF program provided participants with nutrient-dense food, bi-weekly nutrition counseling, and behavioral support. Diabetes Favorable Participants demonstrated significant reductions in BMI and improved dietary behaviors, including decreased consumption of sodium, sugar, and fats. While changes in A1C levels were not statistically significant, the overall trend indicated improvement. Dela J Public Health . Siren 40331171 https://doi.org/10.32481/djph.2025.04.04 https://pubmed.ncbi.nlm.nih.gov/40331171/
An urban farm-anchored produce prescription program's impacts on weight reduction Fruin, Kaitlyn M; Tung, Elizabeth L; Franczyk, Jean M; James, Ketaurah; Koetz, Andrew J; Mason, Angela K; Detmer, Wayne M 2025 Other Linking Intervention and Impact Yes A VeggieRx produce prescription program that refers patients to the Farm on Ogden for free produce boxes, nutrition counseling, and cooking classes. Favorable At eighteen months, the VeggieRx group experienced a mean body weight difference of -6.71 pounds and percentage body weight difference of -4.7 percent relative to control. Health Affairs Siren 40193829 https://doi.org/10.1377/hlthaff.2024.01345 https://pubmed.ncbi.nlm.nih.gov/40193829/
Impact of a multicomponent food-as-medicine intervention on behavioral and mental health outcomes for patients with and without food insecurity Radtke, Marcela D; Tester, June M; Xiao, Lan; Chen, Wei-Ting; Emmert-Aronson, Benjamin O; Markle, Elizabeth A; Chen, Steven; Rosas, Lisa G 2025 Other Linking Intervention and Impact Yes 16-weekly produce deliveries and behavioral intervention sessions. Mental Health Favorable Food-insecure and food-secure patients both experienced significant improvements in loneliness, anxiety, and depressive symptoms from baseline (P < 0.01 for all). Between-group differences were observed only for anxiety, where patients with food security experienced significant improvements in anxious symptoms compared to food-insecure patients (-1.24 [-2.33, -0.14]; P = 0.03). Nutrition Siren 40132449 https://doi.org/10.1016/j.nut.2025.112734 https://pubmed.ncbi.nlm.nih.gov/40132449/
Food as medicine, community as medicine: Mental health effects of a social care intervention Thompson‐Lastad, Ariana; Chiu, Dorothy T; Ruvalcaba, Denise; Chen, Wei‐Ting; Tester, June; Xiao, Lan; Emmert‐Aronson, Benjamin O; Chen, Steven; Rosas, Lisa G 2025 Other Linking Intervention and Impact Yes Recipe4Health, a multisectoral social care partnership implementing produce prescriptions with or without group medical visits (GMVs). Mental Health Favorable Among Food Farmacy‐only participants, post‐intervention depression and anxiety symptoms significantly improved only among those who did not have baseline depression/anxiety (PHQ9: −1.7 [95% CI: −2.8, −0.6]; GAD7: −1.8 [95% CI: −2.9, −0.8]). Among Food Farmacy +GMV participants, mental health symptoms improved regardless of baseline mental health; among those with baseline depression/anxiety: PHQ9: −2.4 (95% CI: −3.6, −1.2); GAD7: −0.9 (95% CI: −2.0, 0.1); among those without: PHQ9: −2.2 (95% CI: −3.2, −1.2); GAD7: −2.2 (95% CI: −3.1, −1.2). Health Serv Res Siren 39775914 https://doi.org/10.1111/1475-6773.14431 https://pmc.ncbi.nlm.nih.gov/articles/PMC12052511/
Assessing the role of socioeconomic factors-income, education, broadband access, and healthy foods on location-wise disparities in COVID-19 cases Chakraborty, A; Shah, J 2025 Other Linking Gap and Impact Yes N/A Favorable Higher income, education level and broadband speed each reduced the probability of violating recommended preventive measures, promoted health awareness, and lowered COVID-19 cases. Conversely, low access to healthy foods increased case counts. The study also reports findings on food habits, living conditions and the link between education and broadband access. Archives of Public Health PubMed 10.1186/s13690-025-01510-w https://link.springer.com/article/10.1186/s13690-025-01510-w
Provision of a daily high protein and high energy meal: Effects on the physical and psychological wellbeing of community-dwelling, malnourished older adults; a randomised crossover trial Struszczak, Lauren; Hickson, Mary; McClelland, Irene; Metcalf, Brad; Barreto, Manuela; Torquati, Luciana; Fulford, Jon; Allen, Rachael; Hulme, Claire; O'Leary, Mary; Bowtell, Joanna 2025 RCT Linking Intervention and Impact Yes Daily home-delivered high-protein (~42 g), high-energy (~715 kcal) meal for 12 weeks vs. no intervention, in 56 community-dwelling malnourished older adults (crossover). Yes No Mental Health Favorable Meal provision increased energy (+311 kcal) and protein intake, improved MNA nutritional status (+2.6 points) and handgrip strength (+1.5 kg). Benefits lost within 12 weeks of withdrawal. Journal of Nutritional Health Aging PubMed 39662153 10.1016/j.jnha.2024.100429 https://pmc.ncbi.nlm.nih.gov/articles/PMC12180064/
Home-Delivered Nutrition Services for Older Adults Under the Older Americans Act Balkan, Em; Gadbois, Emily; Tucher, Emma; Bernard, Kimberly; Thomas, Kali 2025 Other Linking Intervention and Impact Yes Receipt of Older Americans Act home-delivered meals (daily-delivered vs. frozen bulk-shipped) within the Deliver-EE trial; qualitative interviews with 54 recipients. Yes No Favorable Home-delivered meals met all three OAA Nutrition Program goals: reduced hunger/food insecurity/malnutrition, promoted socialization, and promoted health and well-being. Participants also reported benefits to caregivers' health, well-being and finances. The Journal of Nutrition, Health and Aging PubMed 39662153 10.1016/j.jnha.2024.100429 https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2839479
Novel intervention to improve food insecurity among individuals with opioid use disorder: A randomized clinical trial Sigmon, Stacey; Batchelder, Sydney; Badger, Gary 2025 RCT Linking Intervention and Impact Yes 12 weeks of mail-based meal delivery plus nutritional education (NE+MD) vs. nutritional education alone (NE) in 50 adults with food insecurity and opioid use disorder. No Yes Alcohol/Drug Dependence Favorable Food insecurity rates significantly lower in NE+MD vs. NE at all post-intake timepoints (54.6-62.5% vs. 90.5-95.2%). Improvements in food insecurity were associated with reduced depression, better quality of life, and greater illicit opioid abstinence. JAMA Network Open PubMed 41026486 10.1001/jamanetworkopen.2025.34747 https://pubmed.ncbi.nlm.nih.gov/40250065/
Food service interventions and their influence on nutritional outcomes and satisfaction of adult oncology patients—a conceptual replication Steer, Belinda; Black, Jacqueline; Cecchini, Laura; Choo, Clarissa; Dvarakesa, Ana; Hill, Martha; Ho, Athena; Kennett, Georgia; Woltersdorf, Andre; Zilber, Emily; Porter, Judi 2025 Systematic Review Linking Intervention and Impact Yes Hospital and ambulatory food service interventions for adult oncology patients: technology advancement, small frequent high-energy/high-protein meals and snacks, and patient-focused food service models (8 studies). Yes Yes Cancer Favorable Nutritional outcomes (energy and protein intake, body weight, muscle mass) improved in all but one of 8 studies; patient satisfaction improved wherever reported except one study. Study quality was positive for 7 of 8 studies. Drug and Alcohol Dependence PubMed 40250065 10.1016/j.drugalcdep.2025.112673 https://pmc.ncbi.nlm.nih.gov/articles/PMC11850487/
Health-related outcomes of home-delivered meals in community-dwelling older adults aged 60 and over: A systematic review and meta-analysis. Jin, Z.; Struszczak, Lauren; Bowtell, Joanna 2025 Meta Analysis Linking Intervention and Impact No Home-delivered meal programmes for community-dwelling adults aged 60+; systematic search of 6 databases with meta-analysis of health-related outcomes. No Favorable Home-delivered meal interventions improved nutrient status and reduced social loneliness, with no significant effect on body weight or macronutrient intake. Authors call for further high-quality research. Supportive Care in Cancer PubMed 10.1007/s00520-025-09264-5 https://www.cambridge.org/core/journals/proceedings-of-the-nutrition-society/article/healthrelated-outcomes-of-homedelivered-meals-in-communitydwelling-older-adults-aged-60-and-over-a-systematic-review-and-metaanalysis/30415BB41F8DA45BDC377C9CBDE2B9E7
Randomized Controlled Trial in a Real-World Setting Shows a Light Touch “Food Is Medicine” Program Improves Health Behaviors and Self-Reported Health Status in People with Diabetes Wilkin, Maggie; Sun, Betty; McClatchey, Suki 2025 RCT Linking Intervention and Impact No Light-touch 'Food is Medicine' program (Healthy Food Rx produce/food boxes) delivered in a real-world setting to adults with diabetes, evaluated by RCT. Yes Yes Diabetes Favorable Participants showed improved health behaviors (diet quality, physical activity, diabetes self-management) and improved self-reported health status relative to control. Proceedings of the Nutrition Society Google Scholar 10.1017/S0029665125101705 https://diabetesjournals.org/diabetes/article/74/Supplement_1/1895-LB/159228/1895-LB-Randomized-Controlled-Trial-in-a-Real
A Flexible Congregate Meal Program for Older Adults in Hawai'i: A Quasi-Experimental Evaluation of Kūpuna U Lee, Jenny Jinyoung; Sultana, Nargis; Nishita, Christy 2025 Other Linking Intervention and Impact Yes Kupuna U flexible congregate meal program in Hawaii, in three models: virtual (grab-and-go meals + online activities), hybrid, and traditional in-person congregate meals. Yes No Neutral Mixed. Virtual group improved significantly on food insecurity (1.73 to 0.04, p<0.001) and self-rated health (2.92 to 3.72, p=0.005); hybrid group showed a significant increase in loneliness. Diabetes Google Scholar 10.3390/nu17132106 https://www.mdpi.com/2072-6643/17/13/2106
The advantages of diabetes-friendly home-delivered meals Mom's Meals 2026 Case Study Linking Intervention and Impact No Health Plan of Nevada, a UnitedHealthcare Company that services 224,648 Medicaid members, partnered with Mom’s Meals® on a pilot program to support diabetes management by better engaging its members and addressing food insecurity and other social determinants of health. Diabetes Favorable Participants demonstrated better blood sugar control and lower A1c levels by an average of -1.9 points. N/A Grey Lit N/A https://www.momsmeals.com/our-food-programs/medically-tailored-meals/diabetes-friendly/the-advantages-of-diabetesfriendly-homedelivered-meals/
Medically Tailored Meals: A Case for Federal Policy Action Macpherson, Catherine; Frist, William H; Gillen, Emily 2025 Systematic Review Linking Intervention and Impact Yes Medically tailored meals (MTMs) designed by registered dietitians. Favorable Evidence demonstrates that MTMs improve health outcomes, reduce hospitalizations, and lower total cost of care. Case studies from Medicaid and Medicare Advantage plans, including those administered by Mom's Meals®, report reductions in emergency department visits, hospital readmissions, and total cost of care, alongside sustained high member satisfaction. Healthcare Siren 41302287 https://doi.org/10.3390/healthcare13222899 https://pubmed.ncbi.nlm.nih.gov/41302287/
Low-level PM2. 5 exposure, cardiovascular and nonaccidental mortality, and related health disparities in 12 US states Peralta, Adjani; Castro, Edgar; Yazdi, Mahdieh Danesh; Kosheleva, Anna; Wei, Yaguang; Schwartz, Joel 2025 Other Linking Gap and Impact Yes N/A Yes Yes Cardiovascular Disorders Stroke Favorable Each 1-µg/m3 increase in annual PM2.5 was positively associated with all five mortality outcomes: all nonaccidental (1.08%; 95% CI 0.96%, 1.20%), all CVD (1.27%; 95% CI 1.14%, 1.41%), myocardial infarction (1.89%; 95% CI 1.67%, 2.11%), stroke (1.08%; 95% CI 0.87%, 1.30%), and congestive heart failure (2.20%; 95% CI 1.97%, 2.44%). Associations persisted below 8 µg/m3 and among populations under 65. Race modified associations but education did not; highly educated Black residents had a 2.90% larger increase in CVD mortality risk (95% CI 2.42%, 3.39%) than less educated non-Black residents. Epidemiology PubMed 39575927 10.1097/EDE.0000000000001820 https://pubmed.ncbi.nlm.nih.gov/39575927/
Indoor Environmental Quality, Occupant Behaviour, and Health Outcomes in Tropical Urban Residences: An Integrated Field-Based Assessment Khumpairoj, Thanyatorn; Ichinose, Masayuki; Sattayakorn, Sutida 2025 Prosp Cohort Study Linking Gap and Impact Yes N/A Favorable Indoor environmental quality exceedances were significantly associated with increased risk of reported health symptoms. Indoor temperature exceedance was linked to a 2.56-fold increase in throat and cough symptoms (OR = 2.56, p = 0.038) and elevated relative humidity to a 2.27-fold increase in fatigue and cognitive decline (OR = 2.27, p = 0.051). PM2.5 exceedance showed the strongest associations, increasing odds of respiratory symptoms 11.41-fold, throat irritation and coughing 18.29-fold, and eye and skin irritation 4.52-fold (all p < 0.001). Sustainable Built Environment Conference PubMed https://doi.org/10.3929/ethz-c-000785435 https://www.research-collection.ethz.ch/entities/publication/b78c98b4-c8c0-43e2-8b86-d258d8530f17
Food Swamps and Food Deserts Impact on Metabolic Dysfunction–Associated Steatotic Liver Disease Mortality in US Counties Paik, Annette; Henry, Linda; de Avila, Leyla; AlQahtani, Saleh; Nader, Fatema; Paik, James M; Younossi, Zobair M 2025 Other Linking Gap and Impact Yes N/A End-Stage Liver Disease Favorable After adjusting for county sociodemographic and clinical factors and regions, mixed-effects linear regression models showed significant differences in mortality rates (per 100,000) between counties with the highest vs lowest quartiles of food deserts and food swamps. Clinical Gastroenterology and Hepatology PubMed https://doi.org/10.1016/j.cgh.2024.08.053 https://www.cghjournal.org/article/S1542-3565(24)00989-3/fulltext
Nutrition Incentives Associated With Improved Outcomes: 2020–2023 Results From the U.S Gus Schumacher Nutrition Incentive Program Byker Shanks, Carmen; Fung Uy, Whitney; Zhang, Nanhua; Fricke, Hollyanne; Resnicow, Kenneth; Budd Nugent, Nadine; Yaroch, Amy L 2025 Other Linking Intervention and Impact Yes The Gus Schumacher Nutrition Incentive Program supports grantees to implement nutrition incentive projects nationwide to provide individuals participating in the Supplemental Nutrition Assistance Program with incentives to facilitate the purchase and consumption of fruits and vegetables. Yes Yes Favorable Participants in nutrition incentives at >6 months demonstrated significantly higher fruit and vegetable intake than first-time participants and those ≤6 months. Significance was observed for reduced food insecurity and better perceived health. American Journal of Preventive Medicine PubMed https://doi.org/10.1016/j.focus.2025.100348 Nutrition Incentives Associated With Improved Outcomes: 2020–2023 Results From the U.S Gus Schumacher Nutrition Incentive Program - AJPM Focus
Health impacts of health system implementation of a food-as-medicine strategy Ronis, Sarah D; Hartman, Holly; Neeland, Ian J; Leach, Anne; Cunanan, Celina 2025 Case Study Linking Intervention and Impact Yes An unincentivized medically tailored grocery intervention through a regional health system. Yes Yes Neutral MTG program attendance was associated with favorable changes in market attendees vs nonusers in diastolic BP after 3 years from baseline, after accounting for confounders. No significant differences were observed in systolic BP, HbA1c, or weight. American Journal of Managed Care PubMed 40080650 https://doi.org/10.37765/ajmc.2025.89706 Health impacts of health system implementation of a food-as-medicine strategy - PubMed
Voucher for Healthy Foods and Diabetes Control: A Randomized Clinical Trial Persaud, Nav; Zia Ul Haq, Moizza; Buadu, Adelaide 2025 RCT Linking Intervention and Impact Yes Patients with type 2 diabetes experiencing food insecurity were randomly allocated to a monthly voucher or usual access to healthy foods.  Diabetes Neutral In this randomized clinical trial, a monthly food voucher did not have an effect on HbA1c control or objective measures of diet quality but the voucher did increase self-reported vegetable and fruit consumption. Journal of the American Medical Association Internal Medicine PubMed 10.1001/jamainternmed.2025.5420 Voucher for Healthy Foods and Diabetes Control: A Randomized Clinical Trial | Trials | JAMA Internal Medicine | JAMA Network
Impact of a Produce Prescription Program on Health Outcomes, Food Security, and Fruit and Vegetable Intake Valentine, Heather; Cunningham, Alissa; Martin, Donna; Rush, Jessi; Lee, Jaehoon; Gibson, Cheryl A 2025 Other Linking Intervention and Impact Yes Programs provided financial incentives to purchase fruits and vegetables at grocery stores or farmers markets (median, $63/month; duration, 4–10 months). Yes Yes Favorable Odds of improving 1 level in self-reported health status increased for adults and children. Among adults with glycated hemoglobin ≥6.5%, glycated hemoglobin declined by −0.29% age points; among adults with hypertension, systolic and diastolic blood pressures declined by −8.38 mm Hg and −4.94 mm Hg; and among adults with overweight or obesity, BMI decreased by −0.36 kg/m2 . Child BMI z-score did not change −0.01. Cardiovascular Quality and Outcomes Google Scholar https://doi.org/10.1161/CIRCOUTCOMES.122.009520 Impact of Produce Prescriptions on Diet, Food Security, and Cardiometabolic Health Outcomes: A Multisite Evaluation of 9 Produce Prescription Programs in the United States | Circulation: Cardiovascular Quality and Outcomes
Impact of fruit and vegetable incentive programs on food insecurity, fruit and vegetable consumption, and health outcomes: a community guide systematic review Stein, Renee; Finnie, Ramona KC; Harmon, Stacy; Peng, Yinan; Pritchard, Chelsea; Vecsey, Heather; Emmons, Karen M; Hargarten, Stephen; Simon, Melissa A; Blanck, Heidi M 2025 Systematic Review Linking Intervention and Impact Yes This systematic review conducted in support of the Community Preventive Services Task Force examines the effectiveness of Fruit and Vegetable Incentive programs in reducing food insecurity, increasing fruit and vegetable consumption, and improving health outcomes among households with lower incomes. Favorable The findings from this systematic review formed the basis for the CPSTF recommendation of FVI programs for households with lower incomes due to their strong effectiveness in reducing household food insecurity, increasing FV consumption, and improving blood glucose levels among participants at risk for or with diet-related health conditions.  American Journal of Preventive Medicine Google Scholar https://doi.org/10.1016/j.amepre.2024.11.016 Impact of Fruit and Vegetable Incentive Programs on Food Insecurity, Fruit and Vegetable Consumption, and Health Outcomes: A Community Guide Systematic Review - ScienceDirect
Fighting Sickle Cell With Every Bite: Tackling Food Deserts to Reduce Crises and Save Lives Scott, La’Shardae; Cohen-Young, Jasmine 2025 Other Linking Gap and Impact Yes N/A Hematologic Disorders Favorable Findings indicate that individuals with SCD in food deserts experience higher hospitalization rates due to complications related to poor nutrition, such as dehydration, anemia, and infections.  Journal of Sickle Cell Disease Google Scholar https://doi.org/10.1093/jscdis/yoaf013.030 Fighting Sickle Cell With Every Bite: Tackling Food Deserts to Reduce Crises and Save Lives | Journal of Sickle Cell Disease | Oxford Academic
Produce Prescription Subsidy for Patients With Diabetes: A Pragmatic Randomized Clinical Trial Drake, Connor; Buckman, Cierra; Brucker, Amanda; McPeek Hinz, Eugenia; Pignone, Michael; Shaikha, Huda; Rader, Abigail; Granados, Isa; Goldstein, Benjamin A; Chamorro, Ceci 2026 RCT Linking Intervention and Impact Yes The PRx arm received a debit card loaded with $80 monthly for up to 12 months. The card was valid to purchase eligible fresh, frozen, or canned fruits, vegetables, and legumes from grocery retailers. Both arms received diabetes self-management educational materials. Diabetes Unfavorable There were no clinically significant differences in cardiometabolic or health care utilization outcomes between patients who were randomized to receive the subsidy compared with a usual care control group. Journal of the American Medical Association, Internal Medicine Google Scholar doi:10.1001/jamainternmed.2025.8008 Produce Prescription Subsidy for Patients With Diabetes: A Pragmatic Randomized Clinical Trial | Trial Resources | JAMA Internal Medicine | JAMA Network
Untangling the Relationship Between Income,‘Food Deserts,’and Stroke Risk Shaw, Gina 2025 Other Linking Gap and Impact Yes N/A Stroke Neutral In unadjusted models, FD residence (vs non-FD) was associated with higher stroke incidence. After adjustment for age, sex, and race, this relationship was attenuated and no longer statistically significant. Neurology Google Scholar https://doi.org/10.1212/WNL.0000000000213979 Association Between Food Desert Residence and Ischemic Stroke Risk | Neurology
Associations Between Accessing Healthy Food Options and Having Risk of Hypertension Among Baltimore Food Pantry Clients Wang, Shuqi; Lightner, Alexis; Williamson, Stacey; Fan, Wenxuan; Poirier, Lisa; Lewis, Emma C; Jiao, Keyi; Reznar, Melissa M; Neff, Roni A; Kravitz, Julia 2025 Other Linking Intervention and Impact Yes The study assessed clients across pre-packed, client-choice, and multiple-option food pantries. Favorable This study identified a notable relation among eating more pantry-source foods at home, multiple food distribution methods, and having lower SP/DP in a sample of low-income Baltimore adults, suggesting consistent access to pantry foods may be vital in regulating HTP risk for those experiencing food insecurity. Current Developments in Nutrition Google Scholar https://doi.org/10.1016/j.cdnut.2025.106339 Associations Between Accessing Healthy Food Options and Having Risk of Hypertension Among Baltimore Food Pantry Clients - Current Developments in Nutrition
Addressing nutrition insecurity through food prescriptions: Lessons from a safety net health system Prideaux, Melissa; De La Cruz, Maria; Rahman, Himika; LaRue, Denise; Galvan, Esperanza; Bachireddy, Chethan 2025 Other Linking Intervention and Impact Yes Participants receive up to 18 biweekly visits and obtain 20 to 30 pounds of fresh produce along with diabetes self- management education per visit. Patients are also enrolled in Culinary Medicine to increase produce utilization. Diabetes Favorable Graduates have an average HbA1C reduction of 1.09 percentage points compared to their baseline (n = 736, p < 0.00). Of graduates with an initial HbA1C ≥ 9%, HbA1C decreased by an average of 2.22 percentage points (n = 353, p < 0.00) from baseline. LDL levels de clined by 6.07 points (n = 315, p = 0.0038) from baseline. Graduates' average fruit and vegetable consumption increased 20.1% from baseline (n = 708, p < 0.00). Nutrition knowledge improved by 10.6% from baseline to the latest survey (n = 710, p < 0.00). Google Scholar https://doi.org/10.1111/1475-6773.14565 Addressing nutrition insecurity through food prescriptions: Lessons from a safety net health system - Prideaux - 2025 - Health Services Research - Wiley Online Library
DASH-Patterned Groceries and Effects on Blood Pressure: The GoFresh Randomized Clinical Trial Juraschek, Stephen P.; Col, Hannah; Ferro, Kayla; Turkson-Ocran, Ruth-Alma N.; Cluett, Jennifer L.; Davis, Roger B.; Kraemer, Kristen M.; McManus, Kathy; Mukamal, Kenneth J.; Aidoo, Emily L.; Kwapong, Fredrick Larbi; Budu, Marian; Patil, Dhrumil; Nartey, Sarah; Michetti, Jacqueline; Allison, Sofia; Mate-Kole, Manfred; Cao, Jingyi; Grobman, Benjamin; Seager, Reva; Hines, Anika L.; Miller III, Edgar R.; Crews, Deidra C.; Fitzpatrick, Stephanie L. 2026 RCT Linking Intervention and Impact Yes Participants were randomly assigned to 12 weeks of home-delivered, DASH-patterned groceries ordered weekly with dietitian counseling without emphasizing cost or three $500 stipends every 4 weeks intended for self-directed grocery shopping. Favorable In this study, a program of home-delivered, DASH-style groceries plus dietitian counseling decreased BP and LDL cholesterol levels beyond comparable monetary compensation. However, effects were not maintained after the intervention ended. Journal of the American Medical Association Google Scholar doi:10.1001/jama.2025.21112 https://jamanetwork.com/journals/jama/fullarticle/2841256#google_vignette
Impacts of a Produce Prescription Program on Food Security, Diet Quality, and Psychosocial Health of Adults with Medicaid and Chronic Health Conditions: A 12-Month Longitudinal Evaluation Zimmer, Rachel; Abdelfattah, Lindsey; Shenberger, Diane, Crotts, Charlotte; Birken, Sarah; Hanchate, Amresh 2026 Prosp Cohort Study Linking Intervention and Impact Yes Weekly home-delivered produce, registered dietitian-led coaching, and education over 12 months. Favorable PRx was associated with greater improvements in FV intake and greater reductions in loneliness. Between-group differences for FI and moderate-to-severe depression favored PRx but were not statistically significant. At 12 months, no significant between-group differences in healthcare utilization and costs were observed. Among the 105 (84%) intervention participants who completed 12-month follow-up, between the pre- and post-intervention periods, FI declined by 17.1%, FV intake increased by 0.4 cups/day, fatigue improved by 3.1 points, and among participants with elevated baseline BP, systolic BP decreased by 8.6 mmHg. Journal of General Internal Medicine Siren 41979725 https://doi.org/10.1007/s11606-026-10390-x https://pubmed.ncbi.nlm.nih.gov/41979725/
Abstract C144: The association between social determinants of health and cancer screening: Cross-sectional survey results from the National Health Interview Survey Fox, Cameron; Milton, Arissa; Jordan, Lewis; Anderson, Jade; LoConte, Noelle; Narayan, Anand 2025 Other Linking Gap and Impact No N/A Yes Yes Cancer Unfavorable Breast screening: of 8,392 weighted eligible female respondents, 74.6% reported mammography within two years. In both unadjusted and adjusted analyses, food insecurity, lack of internet access, trouble with housing costs, lack of health insurance and transportation difficulties were each associated with significantly lower mammography rates (p<0.01); employment status was not (p>0.10). Colorectal screening: of 14,765 weighted eligible respondents, 69.0% were screened. Unadjusted, food insecurity, lack of college education, lack of internet access, trouble with housing costs, lack of health insurance, employment status and transportation difficulties all showed significantly lower screening (p<0.001); after adjustment only internet access, lack of health insurance, lack of college education and employment status remained significant (all p<0.001), while food insecurity (p=0.224), housing costs (p=0.628) and transportation delays (p=0.090) did not. Authors conclude lack of internet access, health insurance and formal education were independently associated with lower screening and call for targeted SDOH interventions. Cancer Epidemiology, Biomarkers & Prevention (meeting abstract) PubMed 10.1158/1538-7755.DISP25-C144 https://doi.org/10.1158/1538-7755.DISP25-C144
The longitudinal mediating effect of life-space mobility on the relationship between nutritional status and cognitive function in community-dwelling older stroke patients Lei, Yixian; Bai, Haixin; Kang, Hongna; Xin, Qi; Li, Tingting; Yang, Tinghui; Li, Jianan; Meng, Lina 2025 Prosp Cohort Study Linking Gap and Impact Yes N/A Yes Yes Stroke Favorable Nutritional status had a significant total effect on post-stroke cognitive function (Estimate = 0.026, 95% CI 0.022–0.030, p < 0.001) among 284 ischemic stroke patients aged 60 and older followed at 3, 6 and 9 months post-stroke. A significant indirect effect through life-space mobility accounted for 24.94% of the total effect (Estimate = 0.006, 95% CI 0.004–0.008, p < 0.001), with the direct effect remaining significant (Estimate = 0.019, 95% CI 0.015–0.023, p < 0.001), indicating partial mediation. The cross-lagged panel model showed complete mediation for the T2–T3 pathway (β = 0.029, 95% CI 0.004–0.061, p < 0.05). The authors concluded that malnutrition can indirectly worsen post-stroke cognitive impairment via limited life-space mobility, underscoring the value of early malnutrition identification and mobility improvement. Frontiers in Public Health, Vol. 13, Article 1677690 Google Scholar 10.3389/fpubh.2025.1677690 https://doi.org/10.3389/fpubh.2025.1677690
Team-based pilot program incorporates food vouchers to improve health in patients with diabetes Ainooson, Jessica; Gregory, Blake, Sherwin, Elizabeth B.; Lemke, Grace; Narkhede, Anita; Fok, Cynthia L.; Dokanchi, Jack; Flores Crisostomo, Amihan; Khoong, Elaine C. 2026 Other Linking Intervention and Impact Yes Six-month program including pharmacist and nutritionist visits, transportation assistance, and smoking cessation resources, plus $160 per month of grocery and produce vouchers. Diabetes Neutral Uncontrolled hypertension (≥ 140/90 mmHg) decreased significantly from 45.9% to 21.6% (P = 0.007, n = 41). There was no statistically significant change in mean hemoglobin A1c from baseline to program end (10.1% vs 9.7%; P = 0.17). Mean low-density and body mass index were not significantly different. J Nutr Educ Behav Siren 41817481 https://doi.org/10.1016/j.jneb.2026.01.016 https://www.sciencedirect.com/science/article/pii/S149940462600031X
Food Rx + CHW: a community health worker-led medically tailored grocery intervention to address food insecurity and type 2 diabetes, a pilot randomized trial Bridges, Kristina M; Woodward, Jennifer; Murray, Megan; Leibengood, Alyssa; Bantis, Leonidas; Montero, Leny; Young, Donna; Solano, Manuel; Camacho, Vanessa; McCall, Angela; Sullivan, Debra K; Greiner, K Allen 2026 RCT Linking Intervention and Impact Yes Primary care patients with self-reported food insecurity and a diagnosis of type 2 diabetes received 12 weekly home deliveries of fresh produce and shelf-stable foods. About half of the participants were also supported by a community health worker (CHW) providing nutrition education, cooking instruction, and resource linkages. Diabetes Neutral For the Food-only group (n=15), there was no significant change in hemoglobin A1c at either time point. For the Food + CHW group (n=16), the mean change in HbA1c was -0.85 (95% CI, [-0.048, -1.66], P value = 0.039) from baseline to 3 months and -1.65 (95% CI, [-2.84 - 0.472], P value = 0.012) from baseline to 6 months and a majority of participants (81%) had a reduction in hemoglobin A1c at six months. Diastolic blood pressure for the Food-only group increased by an average of 6.5 mmHg (p= 0.02) between baseline and 3 months but remained stable for the Food + CHW group. In both groups, systolic blood pressure and weight did not change significantly. BMC Public Health Siren 41699557 10.1186/s12889-026-26567-2 https://pubmed.ncbi.nlm.nih.gov/41699557/#full-view-affiliation-2
Food insecurity, food assistance, and physical and cognitive functioning among older americans Dhakal, Usha; El Asmar, Khalil; Mendes deLeon, Carlos F. 2025 Other Linking Gap and Impact Yes N/A Yes Yes Favorable Food insecurity is associated with poorer physical and cognitive functioning in older adults. PLoS One Siren https://doi.org/10.1371/journal.pone.0339720 https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0339720
Perceived benefit and impact of a health care-based food pantry: "One Stop Shop" Plencner LM; Kelty K; Demaestri S; Krager M; Marein P; Erbert G; Colvin JD 2025 Other Linking Intervention and Impact Yes An urban children's hospital established an on-site food pantry within the primary care building. Yes Unfavorable Participants reported limited impact on diet and health due to the similarity of the food to their usual diet. Additional themes included the perceived benefit of food pantries within health care as a "one stop shop" and the importance of language concordance and being treated respectfully within the pantry. J Ambul Care Manage Siren 10.1097/JAC.0000000000000544 https://sirenetwork.ucsf.edu/tools-resources/resources/perceived-benefit-and-impact-health-care-based-food-pantry-one-stop-shop
Age at diagnosis and the food environment are associated with postdiagnosis weight gain among Black American breast cancer survivors in Maryland Connor A, Ho K, Dibble K, Visvanathan K 2024 Other Linking Gap and Impact Yes N/A Yes (Average age 58) Favorable Women living in counties with a Food Environment Index ≥8.8 (indicating greater access to healthy foods) were significantly less likely to experience weight gain. Cancer Res Google Scholar 10.1158/1538-7445.SABCS23-PO3-27-07 https://aacrjournals.org/cancerres/article/84/9_Supplement/PO3-27-07/743842
The effectiveness of Recipe4Health: a quasi-experimental evaluation Rosas L, Chen S, Xiao L, Baiocchi M, Ng E, Emmert-Aronson B, Chen W, Thompson-Lastad A, Martinez E, Perez J, Melendez E, Markle E, Radtke M, Tester J 2025 Other Linking Intervention and Impact Yes Recipe4Health had three components: (1) Training and workflow integration for community health centers; (2) Food Farmacy, with 16 weekly doorstep deliveries of produce; (3) Behavioral Pharmacy, with up to 16 weekly group medical visits. Favorable R4H resulted in improvements in diet and multiple clinical health outcomes, such as non-HDL cholesterol and HbA1c. Am J Prev Med Google Scholar 10.1016/j.amepre.2024.10.020 https://www.ajpmonline.org/article/S0749-3797(24)00372-6/fulltext
A systematic review of complementary therapies in colorectal cancer patients: Summarizing the current global options Miftahussurur, M., Camilia, M. A. S., Rezkhita, Y. A. A., Amie, V., Dalla, D., Diah, P., ... & Yamaoka, Y. 2023 Systematic Review Linking Intervention and Impact Yes Systematic review evaluating the effect of complementary therapy, including aromatherapy massage, acupuncture, and mindfulness, on health outcomes and quality of life among colorectal cancer patients. Favorable The review found multiple beneficial health effects of complementary therapies that may improve quality of life among cancer patients. For example, acupuncture significantly improves anxiety, stress, and sleep quality, and Chinese herbal medicine was associated with lower tumor recurrence and metastatic tumor rate. Research Journal of Pharmacy and Technology Google Scholar 10.52711/0974-360X.2023.00252 https://www.indianjournals.com/ijor.aspx?target=ijor:rjpt&volume=16&issue=3&article=088
The music therapy effect on lowering blood pressure in elderly with hypertension: A systematic review Winarto, A., Kusnanto, K., & Harmayetty, H. 2021 Systematic Review Linking Intervention and Impact Yes This review looked at literature on the impact of music therapy on blood pressure. The target population included elderly individuals with hypertension. Yes Favorable The review found 12 eligible studies demonstrating a positive impact on lowering blood pressure from a music therapy intervention. STRADA Jurnal Ilmiah Kesehatan Google Scholar https://doi.org/10.30994/sjik.v10i1.768 https://www.sjik.org/index.php/sjik/article/view/768
A systematic review of complementary therapy for treating osteoarthritis Purnamasari, I., Suharyono, S., Wibowo, S. A., & Soamole, I. 2020 Systematic Review Linking Intervention and Impact Yes This review looked for literature on the impact on complementary therapies on Osteoarthritis. The complementary therapies included were flaxseed poultice compress, acupressure, acupuncture therapy, cumin black oil compress, aromatherapy massage, ginger oil massage, lavender oil massage, sensorimotor exercise, application of heat, exercises with elastic bands, ultrasound therapy, geotherapy combination kinesiotherapy, phonophoresis therapy, and stimulation of compression. Favorable The review found studies that demonstrated the complementary therapy interventions could improve total index WOMAC and Lequesne, VAS and increase in the physical function in the target population. Jurnal Ners Google Scholar http://dx.doi.org/10.20473/jn.v15i2.19025 https://e-journal.unair.ac.id/JNERS/article/download/19025/10359
The effectiveness of aromatherapy in the management of labor pain and anxiety: A systematic review Tabatabaeichehr, M., & Mortazavi, H. 2020 Systematic Review Linking Intervention and Impact Yes This review looked for literature on the impact of aromatherapy on labor pain and anxiety. Favorable The review identified 33 studies that demonstrated positive impact on reducing labor pain and anxiety. Ethiopian Journal of Health Sciences Google Scholar 10.4314/ejhs.v30i3.16 https://www.ajol.info/index.php/ejhs/article/view/195867
Use of complementary therapy in lung cancer patients treated with chemotherapy and its effect on survival: A cross-sectional study Çavdar, E., Karaboyun, K., İriağaç, Y., Avcı, O., & Seber, E. S. 2023 Other Linking Intervention and Impact Yes This study looked at the use, information sharing between physician and patients, and effect on survival of complementary therapies used by lung cancer patients. Cancer Neutral The study found that 60.7% of patients used at least one type of complementary therapy, but physician-patient information sharing was weak and there was not impact on survival. Haseki Tip Bulteni Google Scholar https://acikerisim.nku.edu.tr/xmlui/handle/20.500.11776/12167
Effects of five-element music on language recovery in patients with poststroke aphasia: A systematic review and meta-analysis Yang, Y., Fang, Y. Y., Gao, J., & Geng, G. L. 2019 Systematic Review Linking Intervention and Impact Yes This review looked for literature on the impact of five-element music on language treatment for patients with poststroke aphasia (PSA). Favorable The review identified 6 studies that demonstrated the five-element music intervention had significant effect on increasing language scores compared to western music therapy or the control group. The Journal of Alternative and Complementary Medicine Google Scholar https://doi.org/10.1089/acm.2018.0479 https://www.liebertpub.com/doi/abs/10.1089/acm.2018.0479
Aromatherapy for managing menopausal symptoms: A systematic review and meta-analysis of randomized placebo-controlled trials Lee, H. W., Ang, L., Choi, J., & Lee, M. S. 2021 Systematic Review Linking Intervention and Impact Yes This review looked for literature on the impact of aromatherapy on menopausal symptom management. Favorable The review identified 7 studies that demonstrated improved menopausal symptoms and sexual desire from aromatherapy. The Journal of Alternative and Complementary Medicine Google Scholar https://doi.org/10.1089/acm.2020.0315 https://www.liebertpub.com/doi/abs/10.1089/acm.2020.0315
The effects of mind-body exercise on cognitive performance in elderly: A systematic review and meta-analysis Zhang Y, Li C, Zou L, Liu X, Song W. 2018 Systematic Review Linking Intervention and Impact Yes This review found studies looking at mind-body exercise interventions and their impact on cognitive decline. Yes Favorable The review found 19 eligible studies that demonstrated mind-body exercise had significant positive impact on cognitive performance, global cognition, executive function, learning and memory, and language. Int J Environ Res Public Health PubMed 30544873 10.3390/ijerph15122791 https://pubmed.ncbi.nlm.nih.gov/30544873/
A pilot feasibility randomized controlled trial on combining mind-body physical exercise, cognitive training, and nurse-led risk factor modification to reduce cognitive decline among older adults with mild cognitive impairment in primary care Xu Z, Zhang D, Lee ATC, Sit RWS, Wong C, Lee EKP, Yip BHK, Tiu JYS, Lam LCW, Wong SYS. 2020 Randomized Controlled Trial Linking Intervention and Impact Yes This study looked at the feasibility of a combined intervention of min-body physical exercise, cognitive training, and nurse-led risk factor modification. The aim was to determine the effect on cognitive decline in older adults with mild cognitive impairment. Yes Dementia Favorable The study found the interventions were feasible and showed preliminary results that were beneficial PeerJ PubMed 33194354 10.7717/peerj.9845 https://pubmed.ncbi.nlm.nih.gov/33194354/
Effects of mind-body interventions involving meditative movements on quality of life, depressive symptoms, fear of falling and sleep quality in older adults: A systematic review with meta-analysis Weber M, Schnorr T, Morat M, Morat T, Donath L. 2020 Systematic Review Linking Intervention and Impact Yes This review found literature on mind-body interventions to determine the impact on quality of life, depressive symptoms, fear of falling, and sleep quality. Yes Yes (59+) Favorable The review found 37 eligible studies that demonstrated the intervention had significant impact on all outcomes compared to the control groups. Int J Environ Res Public Health PubMed 32916879 10.3390/ijerph17186556 https://pubmed.ncbi.nlm.nih.gov/32916879/
Mindfulness-based stress reduction for older adults with worry symptoms and co-occurring cognitive dysfunction Lenze EJ, Hickman S, Hershey T, Wendleton L, Ly K, Dixon D, Doré P, Wetherell JL. 2014 Other Linking Intervention and Impact Yes This study looked at the impact of a mindfulness-based stress reduction (MBSR) intervention that included a 8-session group and 12-session group. The study looked at individuals 65+ with significant anxiety-related distress and cognitive dysfunction. Yes No Mental Health Favorable The study found that the intervention led to improvements in worry severity, mindfulness, and memory. There was not a significant difference between the 8 week and 12 week groups. Int J Geriatr Psychiatry PubMed 24677282 10.1002/gps.4086 https://pubmed.ncbi.nlm.nih.gov/24677282/
Mindfulness training and systemic low-grade inflammation in stressed community adults: Evidence from two randomized controlled trials Villalba DK, Lindsay EK, Marsland AL, Greco CM, Young S, Brown KW, Smyth JM, Walsh CP, Gray K, Chin B, Creswell JD. 2019 Randomized Controlled Trial Linking Intervention and Impact Yes This study looked at the impact of a mindfulness training intervention in two rats. The first had a 2-week smartphone-based intervention and the second had an 8-weed mindfulness-based stress reduction (MBSR) intervention. Both studies assigned participants to a monitor and accept group, monitor only group, or control group to understand the impact on inflammation in older adults. Yes Mental Health Neutral The study found the monitor and accept group did not have significant reduction in C-reactive protein (CRP) that was an inflammatory biomarker. They did find that both programs might reduce CRP. PLoS One PubMed 31295270 10.1371/journal.pone.0219120 https://pubmed.ncbi.nlm.nih.gov/31295270/
The effect of moving meditation exercise on depression and sleep quality of the elderly: A randomized controlled study Kerkez M, Erci B. 2024 Randomized Controlled Trial Linking Intervention and Impact Yes This study looked at a move meditation exercise on adults 65+ to under to understand the impact on depression level and sleep quality. Yes No Mental Health Favorable The study found the intervention led to decreased depression and improved quality of sleep. Holist Nurs Pract PubMed 37966990 10.1097/HNP.0000000000000627 https://pubmed.ncbi.nlm.nih.gov/37966990/
Case report: Outcomes of Feldenkrais movements on self-reported cognitive decline in older adults Ullmann G. 2016 Case Study Linking Intervention and Impact Yes This study looked at the impact of the Feldenkrais method awareness through movement (ATM) intervention on cognitive decline in other adults. Yes Favorable There were two participants in the study and both improved the Trail Making Test A and B after the intervention. Adv Mind Body Med PubMed 27250213 https://pubmed.ncbi.nlm.nih.gov/27250213/
Complementary therapy for people with cancer; The patient's perspective Charlesworth, E., Hughes, J., Plant, H., & Carballo, L. 2018 Prospective Cohort Study Linking Intervention and Impact Yes Study evaluating the effect of four complementary therapy outpatient services including aromatherapy, massage, reflexology, and Reiki on a range of health outcomes among cancer patients. Cancer Favorable Patients reported significant improvements after receiving four sessions of complementary therapies; the greatest improvements were seen in relaxation, sleep problems, and pains/aches. European Journal of Integrative Medicine Google Scholar https://doi.org/10.1016/j.eujim.2017.10.009 https://www.sciencedirect.com/science/article/pii/S1876382017302123
The efficacy of complementary therapy for patients receiving palliative cancer care Cedar, S. H., White, M., & Atwal, A. 2018 Prospective Cohort Study Linking Intervention and Impact Yes Study evaluating the effect of six complementary therapy outpatient services on patient wellbeing among patients in palliative cancer care. Cancer Favorable Patients reported significant improvements after receiving a series of six complementary therapies, reporting improved feelings of wellbeing on a standardized scale. International Journal of Palliative Nursing Google Scholar https://doi.org/10.12968/ijpn.2018.24.3.146 https://www.magonlinelibrary.com/doi/abs/10.12968/ijpn.2018.24.3.146
Effect of complementary therapy on hypertension patients: Systematic review Asnaniar, W. O. S., Alam, R. I., & Amir, H. 2021 Other Linking Intervention and Impact Yes Review evaluating the effect of various complementary therapies on health outcomes among patients with hypertension. Cardiovascular Disorders Favorable Study found that the most effective use of therapy was herbal therapy among the elderly, reporting its accessibility and affordability as facilitators to use. However, successfully managing hypertension also requires conventional therapy, exercise, and other methods. Jurnal Ilmiah Kesehatan Google Scholar https://doi.org/10.30994/sjik.v10i2.855 https://sjik.org/index.php/sjik/article/view/855
Effect of complementary therapies in patients following cardiac surgery: A narrative review Chandrababu, R., Nayak, B. S., Pai, V. B., Patil, N. T., George, A., George, L. S., & Devi, E. S. 6f6i Other Linking Intervention and Impact Yes Narrative review evaluating the effect of various complementary therapies on postoperative health outcomes among patients undergoing cardiac surgery. Cardiovascular Disorders Neutral Most studies analyzed reported positive results noting postoperative health improvements in patients after receiving complementary therapies. However, some studies found no evidence of improvement. Holistic Nursing Practice Google Scholar 10.1097/HNP.0000000000000226 https://journals.lww.com/hnpjournal/fulltext/2017/09000/effect_of_complementary_therapies_in_patients.6.aspx
Effects of inhaled ginger aromatherapy on chemotherapy-induced nausea and vomiting and health-related quality of life in women with breast cancer Lua, P. L., Salihah, N., & Mazlan, N. 2015 Randomized Controlled Trial Linking Intervention and Impact Yes Randomized controlled trial evaluating the effect of inhaled ginger aromatherapy on nausea, vomiting, and health-related quality of life among breast cancer patients in chemotherapy. Cancer Neutral Nausea decreased significantly after ginger essential oil inhalation compared to the control group, but effect was not sustained for overall treatment effect. Intervention also had no effect on vomiting. However, global health status significantly changed after ginger inhalation, as well as appetite loss. Complementary Therapies in Medicine Google Scholar https://doi.org/10.1016/j.ctim.2015.03.009 https://www.sciencedirect.com/science/article/pii/S0965229915000540
The effect of music therapy on anxiety and pain in patients undergoing prostate biopsy: A systematic review and meta-analysis He, H., Li, Z., Zhao, X., & Chen, X. 2023 Systematic Review Linking Intervention and Impact Yes Systematic review assessing studies on the effect of music therapy on pain, anxiety, and physiologic parameters among patients undergoing prostate biopsy. Neutral Music therapy only slightly reduced heart rate, but not blood pressure and respiratory rate after biopsy. There is little evidence to suggest that music therapy during prostate biopsy reduces pain and anxiety. Complementary Therapies in Medicine Google Scholar https://doi.org/10.1016/j.ctim.2022.102913 https://www.sciencedirect.com/science/article/pii/S0965229922001169
Complementary approaches to decreasing discomfort during shockwave lithotripsy (SWL) Ngee-Ming, G., Tamsin, D., Rai, B. P., & Somani, B. K. 2014 Other Linking Intervention and Impact Yes Systematic review evaluating studies on the effect of complementary therapies including acupuncture, auricular acupressure, transcutaneous electrical nerve stimulation, and music during shock wave lithotripsy among patients with renal stones. Neutral Complementary therapy music and acupuncture significantly lowered anxiety. However, there was no reported difference in stone-free rates among patients with the use of complementary therapy. Urolithiasis Google Scholar https://link.springer.com/article/10.1007/s00240-014-0655-2
Clinical outcomes in hypertensive or diabetes patients who concomitantly use complementary medicines in Lagos, Nigeria Olayemi, S. O., Nwaiwu, O., Fasanmade, O., Aro, A. O., & Ibrahim, A. 2015 Other Linking Intervention and Impact Yes Observational study evaluating the effect of various complementary therapies on clinical outcomes among hypertensive or diabetic patients. Cardiovascular Disorders Diabetes Neutral Use of complementary medicine was associated with reduced blood pressure. Complementary medicines were found to have positive effects on health in hypertensive patients but not diabetic patients, though results were not statistically significant. East African Medical Journal Google Scholar https://www.ajol.info/index.php/eamj/article/view/118813
Effect of music on outpatient urological procedures: A systematic review and meta-analysis from the European Association of Urology Section of Uro-Technology Kyriakides, R., Jones, P., Geraghty, R., Skolarikos, A., Liatsikos, E., Traxer, O., ... & Somani, B. K. 2018 Systematic Review Linking Intervention and Impact Yes Systematic review and meta-analysis evaluating the effect of music therapy on outcomes of outpatient urological procedures. Favorable Music therapy decreased anxiety and pain among patients in surgery, and increased procedural satisfaction and patient willingness to undergo the procedure again. The Journal of Urology Google Scholar https://doi.org/10.1016/j.juro.2017.11.117 https://www.sciencedirect.com/science/article/pii/S002253471778038X
Effect of music therapy on anxiety levels among infertile women undergoing IVF procedures: A randomized control trial Vaithianathan, H., Chelladurai, R., Gopinath, P. M., Venkatesh, D., Jagadeesan, V. S., & Chokkalingam, P. V. 2021 Systematic Review Linking Intervention and Impact Yes Systematic review and meta-analysis evaluating the effect of music therapy on anxiety and pregnancy rates among infertile women undergoing to perform assisted reproductive technologies. Favorable Music therapy significantly reduced anxiety and pain, and improved satisfaction. Music also was associated with a statistically insignificant increase in the pregnancy rate among the population. Journal of Psychosomatic Obstetrics and Gynaecology Google Scholar 10.1080/0167482X.2021.1977277 https://www.fertstert.org/article/S0015-0282(21)01566-1/abstract
Effect of spiritist “passe” on preoperative anxiety of surgical patients Carneiro, É. M., Tosta, A. D. M., Antonelli, I. B. S., Soares, V. M., Oliveira, L. F. A., Borges, R. M. C., ... & Borges, M. D. F. 2020 Randomized Controlled Trial Linking Intervention and Impact Yes Randomized controlled trial evaluating the effect of spiritist "passes", laying on of hand with the intention of healing, on preoperative anxiety among hospitalized patients. Favorable "Passe" intervention group reported greater improvements in preoperative anxiety, muscle tension, and wellbeing compared to the control group. Journal of Religion and Health Google Scholar https://link.springer.com/article/10.1007/s10943-019-00841-7
The impact of complementary and alternative medicines on cancer symptoms, treatment side effects, quality of life, and survival in women with breast cancer Leggett, S., Koczwara, B., & Miller, M. 2015 Systematic Review Linking Intervention and Impact Yes Systematic review evaluating studies on the effect of oral complementary alternative medicines (tablets, powders, liquids, capsules) on cancer-related health outcome among breast cancer patients. Cancer Neutral Study results vary, but there is some evidence to suggest that oral complementary alternative therapies may improve fatigue and oral mucositis. However, results are inconclusive. Nutrition and Cancer Google Scholar  10.1080/01635581.2015.1004731 https://www.tandfonline.com/doi/abs/10.1080/01635581.2015.1004731
Essential oil therapy in rheumatic diseases: A systematic review Paixão, V. L. B., & de Carvalho, J. F. 2021 Systematic Review Linking Intervention and Impact Yes Systematic review evaluating studies on the effect of essential oil therapy on health outcomes among patients with rheumatic diseases. Favorable Nearly all studies analyzed demonstrated the effectiveness of aromatherapy for improving health outcomes among patients. Complementary Therapies in Clinical Practice Google Scholar https://doi.org/10.1016/j.ctcp.2021.101391 https://www.sciencedirect.com/science/article/pii/S1744388121000906
Efficacy of integrated yoga and Ayurveda Rasayana on cognitive functions in elderly with mild cognitive impairment: Non-randomized three-arm clinical trial Chobe S, Patra SK, Chobe M, Metri K. 2022 Other Linking Intervention and Impact Yes This study looked at the impact of an 8-week Yoga and/or Ayurveda Rasayana intervention in older adults with mild cognitive impairment. Yes Yes (mean 63.3 +/- 6.44) Favorable This study found the combined intervention of Yoga and Ayurveda Rasayana had significant results in improving learning, attention, processing speed, and working memory in the study group. J Ayurveda Integr Med PubMed 33349568 10.1016/j.jaim.2020.11.003 https://pubmed.ncbi.nlm.nih.gov/33349568/
Effects of 12 weeks of tai chi on neuromuscular responses and postural control in elderly patients with sarcopenia: A randomized controlled trial Huang D, Ke X, Jiang C, Song W, Feng J, Zhou H, Zhang R, Zhang A, Lan F. 2023 Randomized Controlled Trial Linking Intervention and Impact Yes This study looked at a 12-week Tai Chi program to understand the impact on neuromuscular responses and postural control. The intervention included 40-minute sessions 3 times a week for 12 weeks for elderly patients with sarcopenia. Yes Favorable The study found that the Tai Chi intervention significantly reduced neuromuscular response times. Front Neurol PubMed 37188307 10.3389/fneur.2023.1167957 https://pubmed.ncbi.nlm.nih.gov/37188307/
The effect of tai chi exercise intervention on sleep quality in community residing older adults: A systematic review and meta-analysis Lyu L, Li Y, Fan X, Seo J, Eunna O. 2024 Systematic Review Linking Intervention and Impact Yes This review looked at literature on the impact of Tai Chi on sleep quality for older adults living in the community. Yes Favorable The review identified 12 eligible studies that demonstrated the Tai Chi intervention led to significant improvement in sleep quality in the target population. Eur Geriatr Med PubMed 38227110 10.1007/s41999-023-00923-6 https://pubmed.ncbi.nlm.nih.gov/38227110/
The impact of combined music and tai chi on depressive symptoms among community-dwelling older persons: A cluster randomized controlled trial Liao SJ, Tan MP, Chong MC, Chua YP. 2018 Randomized Controlled Trial Linking Intervention and Impact Yes This study looked at the impact of a Tai Chi intervention combined with music on depressive symptoms in older adults. Yes Mental Health Favorable The study found that the combined Tai Chi and Music intervention significantly reduced depressive symptoms after three months. Issues Ment Health Nurs PubMed 29436896 10.1080/01612840.2017.1417519 https://pubmed.ncbi.nlm.nih.gov/29436896/
The role of tai chi in mental health management-lessons learned from clinical trials Jiang D, Kong W, Jiang JJ. 2016 Other Linking Intervention and Impact Yes This review looked at research on the impact of Tai Chi interventions on mental health. Neutral The review found 21 eligible studies, but there was limited evidence found on the impact of Tai Chi on mental health. Rev Recent Clin Trials PubMed 27480968 10.2174/1574887111666160729100829 https://pubmed.ncbi.nlm.nih.gov/27480968/
Military-tailored yoga for veterans with Post-Traumatic Stress Disorder Cushing RE, Braun KL, Alden C-Iayt SW, Katz AR. 2018 Other Linking Intervention and Impact Yes This study looked at the impact of Yoga on PTSD symptoms in veterans 18 years or older. No Yes (26 - 62) Mental Health Favorable The study found that the Yoga intervention led to a significant decrease in PTSD symptoms. Mil Med PubMed 29415222 10.1093/milmed/usx071 https://pubmed.ncbi.nlm.nih.gov/29415222/
The effectiveness of mind-body approaches for enhancing resilience in older adults: A systematic review and network meta-analysis Wu YC, Shen SF, Lee SY, Chen LK, Tung HH. 2023 Systematic Review Linking Intervention and Impact Yes This review found studies looking at the impact of mind-body approach interventions on improving resilience in older adults. Yes Favorable The review found 9 eligible studies that demonstrated mind-body approaches improved resilience in older adults. Arch Gerontol Geriatr PubMed 36796181 10.1016/j.archger.2023.104949 https://pubmed.ncbi.nlm.nih.gov/36796181/
Effects of traditional Chinese mind-body exercises on older adults with cognitive impairment: A systematic review and meta-analysis Yao KR, Luo Q, Tang X, Wang ZH, Li L, Zhao L, Zhou L, Li L, Huang L, Yin XH. 2023 Systematic Review Linking Intervention and Impact Yes This review found studies looking at the impact of mind-body approach interventions on improving cognition, memory, and executive function in older adults with cognitive impairment. Yes Favorable The review found 15 eligible studies that demonstrated a significant improvement in global cognitive function from Chinese mind-body exercises. Banduanjuin showed significant improvement in global cognitive function, memory function, executive function, and some dimensional scores on the auditory verbal learning test after treatment. Front Neurol PubMed 37077563 10.3389/fneur.2023.1086417 https://pubmed.ncbi.nlm.nih.gov/37077563/
The effect of music therapy on cognitive functions in patients with dementia: A systematic review and meta-analysis Fusar-Poli L, Bieleninik Ł, Brondino N, Chen XJ, Gold C. 2018 Systematic Review Linking Intervention and Impact Yes This review found studies looking at the impact of music therapy on the cognitive function of individuals with dementia. Yes No Dementia Neutral This review found 7 eligible studies but no significant impact of music therapy on outcomes from the meta-analyses. A subgroup analysis indicated that music therapy might benefit global cognition. Aging Ment Health PubMed 28691506 10.1080/13607863.2017.1348474 https://pubmed.ncbi.nlm.nih.gov/28691506/
Hypnosis to reduce fear of falling in hospitalized older adults: A feasibility randomized controlled trial Cuvelier C, Hars M, Zamorani-Bianchi MP, Herrmann FR, Wieczorkiewicz CD, Zekry D, Gold G, Trombetti A. 2023 Randomized Controlled Trial Linking Intervention and Impact Yes The study looked at the feasibility of a hypnosis intervention of 2 sessions, once per week, with the usual rehabilitation program compared to a control group. The aim was to understand the impact on older adults a reduce the fear of falling. Yes Favorable The study was found to be feasible with no adverse events related to the intervention. Pilot Feasibility Stud PubMed 37559112 10.1186/s40814-023-01366-3 https://pubmed.ncbi.nlm.nih.gov/37559112/
Non-pharmacological depression therapies for older Chinese adults: A systematic review & meta-analysis Gill BK, Cant R, Lam L, Cooper S, Lou VWQ. 2020 Systematic Review Linking Intervention and Impact Yes This review found studies looking at the impact of different non-pharmacologic interventions on depression for older Chinese adults. Yes Mental Health Favorable The review found 15 eligible studies that identified Qigong, reminiscence, Tai Chi, and Life Stories as interventions used for depression therapies. Qigong was the only intervention they found to have significant impact on depression. Arch Gerontol Geriatr PubMed 32135393 10.1016/j.archger.2020.104037 https://pubmed.ncbi.nlm.nih.gov/32135393/
Interventions incorporating physical and cognitive elements to reduce falls risk in cognitively impaired older adults: A systematic review Booth V, Hood V, Kearney F. 2016 Systematic Review Linking Intervention and Impact Yes This review found studies that looked at the impact of interventions that combined physical and cognitive elements and the impact on the risk of falls in cognitively impaired older adults. These interventions included physical and cognitive activities, music-based group exercises, and mind-body tai chi. Yes No Favorable The review found 8 eligible studies that demonstrated the interventions improved the number of falls, balance, functional mobility, and gait speed. JBI Database System Rev Implement Rep PubMed 27532469 10.11124/JBISRIR-2016-002499 https://pubmed.ncbi.nlm.nih.gov/27532469/
Hypnosis can reduce pain in hospitalized older patients: A randomized controlled study Ardigo S, Herrmann FR, Moret V, Déramé L, Giannelli S, Gold G, Pautex S. 2016 Randomized Controlled Trial Linking Intervention and Impact Yes This study looked at the impact of hypnosis versus message interventions on chronic pain in older, hospitalized adults. Yes The study found the interventions were feasible and the hypnosis group had greater decrease in the brief pain index than the massage group and depression scores also decreased over time. However, the effect was not long term past 3 months. BMC Geriatr PubMed 26767506 10.1186/s12877-016-0180-y https://pubmed.ncbi.nlm.nih.gov/26767506/
Increasing awareness and acceptance through mindfulness and somatic education movements Bloise PV, Andrade MC, Machado H, Andreoli SB. 2016 Other Linking Intervention and Impact Yes This study looked at the impact of mindfulness-based interventions (MBI). The study looked at the BMI program, Mindfulness and Movement of Integration (MMI). Yes (18+) Favorable The study found significant improvement in the Mindful Attention Awareness Scale (MAAS) scores and the Philadelphia Mindfulness Scale (PHLMS) scores from the intervention. The correlation between scores was not significant. Adv Mind Body Med PubMed 27925606 https://pubmed.ncbi.nlm.nih.gov/27925606/
Reduced stress and improved physical functional ability in elderly with mental health problems following a horticultural therapy program Han AR, Park SA, Ahn BE. 2018 Other Linking Intervention and Impact Yes This study looked at the impact of a horticultural intervention that included once-weekly sessions of a 10-session plan cultivation-based horticultural therapy program. Favorable The study found the intervention significantly decreased cortisol levels. Complement Ther Med PubMed 29857876 10.1016/j.ctim.2018.03.011 https://pubmed.ncbi.nlm.nih.gov/29857876/
The effects of light therapy on depression and sleep disruption in older adults in a long-term care facility Wu MC, Sung HC, Lee WL, Smith GD. 2015 Other Linking Intervention and Impact Yes This study looked at the impact of a light therapy intervention that included 30 min of sitting in front of a 10000-lux light box 30 min three times a week for 4 weeks. The aim was to determine the impact on depression and sleep disruption in older adults. Mental Health Neutral The study found the intervention significantly decreased depression scores, but there was not significant difference between the experimental group and control group. Int J Nurs Pract PubMed 24750268 10.1111/ijn.12307 https://pubmed.ncbi.nlm.nih.gov/24750268/
Use of music therapy to improve cognition in older adults with dementia: An integrative review Domínguez-Chávez CJ, Salazar-González BC, Murrock CJ. 2019 Other Linking Intervention and Impact Yes This review found literature on the impact of music therapy interventions on cognition in older adults with dementia. Yes Dementia Favorable The review identified 28 eligible articles that demonstrated that active and active-passive approaches had significant impact on cognition in the target population. Res Theory Nurs Pract PubMed 31123162 10.1891/1541-6577.33.2.183 https://pubmed.ncbi.nlm.nih.gov/31123162/
Dog visiting programs for managing depressive symptoms in older adults: A meta-analysis Borgi M, Collacchi B, Giuliani A, Cirulli F. 2020 Meta Analysis Linking Intervention and Impact Yes This study found literature on the impact of an animal-assisted intervention (AAI), dog visiting, for depressive symptoms in older adults. yes Mental Health Favorable This review found studies that demonstrated a positive impact on depressive symptoms from dog visiting. Gerontologist PubMed 30476083 10.1093/geront/gny149 https://pubmed.ncbi.nlm.nih.gov/30476083/
Randomized controlled trial of a six-week spiritual reminiscence intervention on hope, life satisfaction, and spiritual well-being in elderly with mild and moderate dementia Wu LF, Koo M. 2016 Randomized Controlled Trial Linking Intervention and Impact Yes This study looked at the impact of spiritual reminiscence therapy on the well-being of elderly individuals with dementia. Yes Dementia Favorable The study found the intervention had significant improvement in the Heart Hope index, the Life Satisfaction Scale, and the Spirituality Index of Well-Being. Int J Geriatr Psychiatry PubMed 25965388 10.1002/gps.4300 https://pubmed.ncbi.nlm.nih.gov/25965388/
A performing arts intervention improves cognitive dysfunction in 50 hospitalized older adults Danila MI, Melnick JA, Mudano A, Flood K, Booth K, Kirklin K, Saag KG. 2018 Other Linking Intervention and Impact Yes This study looked at a storytelling/poetry intervention for hospitalized older adults to understand the effect on delirium screening and patient satisfaction. Yes Favorable The study found the intervention led to lower delirium screening scores. Innov Aging PubMed 29938231 10.1093/geroni/igy013 https://pubmed.ncbi.nlm.nih.gov/29938231/
Are mind-body exercise beneficial for treating pain, function, and quality of life in middle-aged and old people with chronic pain? A systematic review and meta-analysis Wen YR, Shi J, Wang YF, Lin YY, Hu ZY, Lin YT, Wang XQ, Wang YL. 2022 Systematic Review Linking Intervention and Impact Yes This study looked at a Mind-body exercise program (MBE) and how it impacted chronic pain, function, quality of life, and adverse events in older and middle-aged people. Yes Yes Favorable The review found 17 eligible studies that demonstrated the MBE intervention led to reduced pain, but with low-certainty evidence. Front Aging Neurosci PubMed 35800981 10.3389/fnagi.2022.921069 https://pubmed.ncbi.nlm.nih.gov/35800981/
Effect of tai chi combined with mental imagery on cutaneous microcirculatory function and blood pressure in a diabetic and elderly population Alsubiheen A, Petrofsky J, Yu W, Lee H. 2020 Other Linking Intervention and Impact Yes This study looked at the impact of a Tai Chi (TC) training intervention combined with mental imagery (MI) on individuals with diabetes. The intervention was a one hour session twice a week for 8 weeks to study the impact on blood pressure and cutaneous microcirculatory function. Diabetes Favorable The study found the Tai Chi and mental imagery combined intervention had posstive impact on functional outcomes and blood pressure. Healthcare (Basel) PubMed 32947783 10.3390/healthcare8030342 https://pubmed.ncbi.nlm.nih.gov/32947783/
Feasibility and outcome of an individualized tai chi program for improving balance and strength in the elderly: A pilot study Sung WH, Liu CC, Wei SH, Chuang LR, Chuang E, Wang KA, Wang JC. 2018 Other Linking Intervention and Impact Yes This study aimed to test the feasibility of an individualized Tai Chi program for older adults. Yes Favorable The study found the individualized Tai Chi intervention showed improved performance on balance control. NeuroRehabilitation PubMed 30400109 10.3233/NRE-162061 https://pubmed.ncbi.nlm.nih.gov/30400109/
Effect of a 12-week yoga therapy program on mental health status in elderly women inmates of a hospice Ramanathan M, Bhavanani AB, Trakroo M. 2017 Other Linking Intervention and Impact Yes This study looked a t the impact of a 12-week yoga intervention that had 60 min session twice a week. The study looked at the impact of the program on mental health status in elderly women inmates. Yes Favorable The study found that the Yoga intervention led to an increase in the level of self esteem and decrease in depression and anxiety. Int J Yoga PubMed 28149064 10.4103/0973-6131.186156 https://pubmed.ncbi.nlm.nih.gov/28149064/
Yoga meditation (YoMed) and its effect on proprioception and balance function in elders who have fallen: A randomized control study Wooten SV, Signorile JF, Desai SS, Paine AK, Mooney K. 2018 Randomized Controlled Trial Linking Intervention and Impact Yes The study looked at the impact of a 6 week Yoga intervention for older individuals with 45 minute sessions 3 days a week. The study analyzed the impact of the intervention on proprioception, balance and power in older individuals who have fallen in a YoMed group (YM) and a Proprioception Training Group (PT). Yes Neutral The study found that neither the YM or PT group saw changes in measures outside of the dynamic posturography overall score, which was improved in the YM group. Complement Ther Med PubMed 29458919 10.1016/j.ctim.2017.12.010 https://pubmed.ncbi.nlm.nih.gov/29458919/
Effect of tai chi on cardiac and static pulmonary function in older community-dwelling adults at risk of ischemic stroke: A randomized controlled trial Zheng GH, Zheng X, Li JZ, Duan TJ, Tao J, Chen LD. 2019 Randomized Controlled Trial Linking Intervention and Impact Yes This study looked at the impact of a Tai Chi Exercise intervention for older community-dwelling adults. The intervention include 60 minutes sessions five times a week for 12 weeks to understand the impact on cardiac and static lung function. Yes Yes (55+) Stroke Neutral The study did not show significant changes in any of the measures analyzed and would need longer duration interventions studies. Chin J Integr Med PubMed 30519872 10.1007/s11655-018-3056-5 https://pubmed.ncbi.nlm.nih.gov/30519872/
A randomized preference trial comparing cognitive-behavioral therapy and yoga for the treatment of late-life worry: Examination of impact on depression, generalized anxiety, fatigue, pain, social participation, and physical function Danhauer SC, Miller ME, Divers J, Anderson A, Hargis G, Brenes GA. 2022 Other Linking Intervention and Impact Yes The study looked at the effect of Cognitive-Behavioral Therapy and Yoga interventions. Yes Yes (60+) Favorable The study found that the CBT group had more improvement in pain interference group than the yoga group. Both intervention groups had significant changes in depressive symptoms, generalized anxiety, and fatigue. Neither group showed difference in physical function or social participation. Glob Adv Health Med PubMed 35601466 10.1177/2164957X221100405 https://pubmed.ncbi.nlm.nih.gov/35601466/
Online chair yoga and digital learning for rural underserved older adults at risk for Alzheimer's disease and related dementias Park J, Wiese LAK, Holt J. 2023 Other Linking Intervention and Impact Yes This study looked at the impact of a home-based online chair yoga program and computer brain game (CBG) that included 45 minute sessions 2 times a week for 12 weeks. The study analyzed rural community-dwelling older adults. Yes Favorable The study found that both groups had significant improvement in pain interference, cognitive function, mobility and computer skills. There was not a difference between the groups. Clin Gerontol PubMed 37941382 10.1080/07317115.2023.2277333 https://pubmed.ncbi.nlm.nih.gov/37941382/
Simplified tai chi program training versus traditional tai chi on the functional movement screening in older adults Wang H, Wei A, Lu Y, Yu B, Chen W, Lu Y, Liu Y, Yu D, Zou L. 2016 Other Linking Intervention and Impact Yes This study looked at two Tai Chi programs to understand the impact on the Functional Movement Screening (FMS). This included a traditional Tai Chi exercise (TTC) and simplified Tai Chi exercise (TCRT) in older adults. Yes Yes Favorable The study found that both groups had significant improvement in FMS scores after 6 months. The TCRT group had greater improvement than the TCC group Evid Based Complement Alternat Med PubMed 27956920 10.1155/2016/5867810 https://pubmed.ncbi.nlm.nih.gov/27956920/
Different modulation effects of tai chi chuan and Baduanjin on resting-state functional connectivity of the default mode network in older adults Liu J, Tao J, Liu W, Huang J, Xue X, Li M, Yang M, Zhu J, Lang C, Park J, Tu Y, Wilson G, Chen L, Kong J. 2019 Other Linking Intervention and Impact Yes This study looked at the impact two mind-body interventions including Tai Chi Chuan and Banuanjin. The study focused on elderly individuals. Yes Yes (50 - 70) Favorable The study found the Tai Chi Chuan group to have greater improvement of rsFC. Tai Chi Chuan also increased posterior cingulate cortex rsFC. Banduanjin decreased rsFC between the mPFC and orbital prefonal gyrus/putamen. Soc Cogn Affect Neurosci PubMed 30690554 10.1093/scan/nsz001 https://pubmed.ncbi.nlm.nih.gov/30690554/
Effects of a modified tai chi program on older people with mild dementia: A randomized controlled trial Huang N, Li W, Rong X, Champ M, Wei L, Li M, Mu H, Hu Y, Ma Z, Lyu J. 2019 Randomized Controlled Trial Linking Intervention and Impact Yes This study looked at the impact of a Tai Chi exercise program for older adults with mild dementia. Yes Dementia Favorable The study found that the Tai Chi intervention might improve cognitive function and mental well being in the study population. J Alzheimers Dis PubMed 31743998 10.3233/JAD-190487 https://pubmed.ncbi.nlm.nih.gov/31743998/
The effect of chair yoga in older adults with moderate and severe Alzheimer's disease McCaffrey R, Park J, Newman D, Hagen D. 2014 Other Linking Intervention and Impact Yes This study looked at the feasibility of an 8-week chair yoga program (Sit'N'Fit Chair Yoga Program) for older adults with Alzheimer's. Yes Dementia Favorable This study found positive impact of the program in Six-Minute Walk test, the Gait Speed Test, and the Berg Balance Scale. Res Gerontol Nurs PubMed 24568209 10.3928/19404921-20140218-01 https://pubmed.ncbi.nlm.nih.gov/24568209/
Meditation and cognitive outcomes: longitudinal analysis using data from the health and retirement study 2000-2016 Lopes S, Shi L, Pan X, Gu Y, Dengler-Crish C, Li Y, Tiwari B, Zhang D. 2023 Other Linking Intervention and Impact Yes This study looked at a medication practice and cognitive function intervention. The study aimed to understand the impact on cognitive function in middle aged and older adults. Yes yes Favorable The study did not find meditation to be significantly related to total recall, global cognitive function and quantitative reasoning among the full group. Participants that did not have depressive symptoms at the start of the study did show positive changes in cognitive outcomes with medication more than twice a week. Mindfulness (N Y) PubMed 37808263 10.1007/s12671-023-02165-w https://pubmed.ncbi.nlm.nih.gov/37808263/
An investigation to study the effects of tai chi on human gait dynamics using classical machine learning Faisal MAA, Chowdhury MEH, Khandakar A, Hossain MS, Alhatou M, Mahmud S, Ara I, Sheikh SI, Ahmed MU. 2022 Other Linking Intervention and Impact Yes This study looked at the impact of a 6-month Tai Chi intervention on joint function for knee osteoarthritis patients. Favorable The study found Tai Chi to positively impact walking gait dynamics. Comput Biol Med PubMed 35016098 10.1016/j.compbiomed.2021.105184 https://pubmed.ncbi.nlm.nih.gov/35016098/
Correlation between cognition and balance among middle-aged and older adults observed through a tai chi intervention program Xiao T, Yang L, Smith L, Loprinzi PD, Veronese N, Yao J, Zhang Z, Yu JJ. 2020 Other Linking Intervention and Impact Yes This study looked at the impact of Tai Chi (TC) on balance and global cognitive function. The intervention was 12 weeks with a focus on middle aged and older adults. Yes Yes Favorable The study found Tai Chi was positively correlated with change scores of cognitive function and balance. Front Psychol PubMed 32328017 10.3389/fpsyg.2020.00668 https://pubmed.ncbi.nlm.nih.gov/32328017/
Effects of a short eight tai chi-forms for the pre-frail elderly people in senior living communities Ge Y, Liu H, Wu Q, Chen A, Gao Z, Xing F, Liu G. 2022 Randomized Controlled Trial Linking Intervention and Impact Yes The study looked at the impact of an 8 week 8 form Tai Chi exercise intervention on pre-frail elderly individuals. The study observed the impact on physical function, fear of falling, and depression. Yes Favorable The study showed the 8-form Tai Chi intervention had significant positive impact on 30s chair rise tests, fear of falling and the Geriatric Depression Scale at week 8 of the intervention.. Physiother Theory Pract PubMed 34076569 10.1080/09593985.2021.1926023 https://pubmed.ncbi.nlm.nih.gov/34076569/
Effects of tai chi on cognition and instrumental activities of daily living in community dwelling older people with mild cognitive impairment Siu MY, Lee DTF. 2018 Randomized Controlled Trial Linking Intervention and Impact Yes This study looked at the impact of a Tai Chi program that included two one-hour sessions a week for 16 weeks. The goal was to determine the intervention effect on instrumental activities of daily living (IADL) on community-dwelling individuals 60+ with mild cognitive impairment (MCI). Yes Yes (60+) Favorable The study found the Tai Chi intervention significantly improved scores on the Chinese version of the Mini-Mental State Examination (CMMSE) and IADL questionnaire. Minimum detectable change (MDC) was not exceeded. BMC Geriatr PubMed 29394884 10.1186/s12877-018-0720-8 https://pubmed.ncbi.nlm.nih.gov/29394884/
A systematic review of the effect of laughter yoga on physical function and psychosocial outcomes in older adults Kuru Alici N, Arikan Dönmez A. 2020 Systematic Review Linking Intervention and Impact Yes This study reviewed literature analyzing the impact of laughter yoga on physical function and psychosocial outcomes. Yes Favorable The study found 7 eligible studies that demonstrated a significant impact on physical function and psychosocial health from laughter interventions. Complement Ther Clin Pract PubMed 33217706 10.1016/j.ctcp.2020.101252 https://pubmed.ncbi.nlm.nih.gov/33217706/
The effect of tai chi lower extremity exercise on the balance control of older adults in assistant living communities Mao M, Mercer VS, Li F, Gross MT, Blackburn T, Yu B. 2024 Randomized Controlled Trial Linking Intervention and Impact Yes This study looked at an 16-week Tai Chi program to understand the impact it had on balance and functional mobility for older adults. Yes No Favorable The study found the Tai Chi intervention led to significant improvement in the Berg Balance Scale (BBS), Timed Up and Go (TUG) test, room mean square amplitude of COP displacement in the anterior-posterior, and medial, lateral directions. BMC Complement Med Ther PubMed 38448853 10.1186/s12906-024-04382-9 https://pubmed.ncbi.nlm.nih.gov/38448853/
The benefits of tai chi and brisk walking for cognitive function and fitness in older adults Ji Z, Li A, Feng T, Liu X, You Y, Meng F, Wang R, Lu J, Zhang C. 2017 Other Linking Intervention and Impact Yes This cross-sectional study looked at the impact of different exercises on cognitive tasks. The study groups included a Tai Chi (TC) group, a brisk walking group (BG) and a control group (CG). Yes Favorable The study found the TC and BG intervention groups had significantly improved executive condition of cognitive tasks and fitness than the CG. The study did not find significant results for reaction time. PeerJ PubMed 29062610 10.7717/peerj.3943 https://pubmed.ncbi.nlm.nih.gov/29062610/
The effect of Bikram yoga on endothelial function in young and middle-aged and older adults Hunter SD, Dhindsa MS, Cunningham E, Tarumi T, Alkatan M, Nualnim N, Elmenshawy A, Tanaka H. 2017 Other Linking Intervention and Impact Yes This study looked at the impact of Bikram yoga intervention of 3 weekly classes for 8 weeks on endothelial function in young, middle-aged, and older adults. Yes Yes Favorable The study found that brachial artery flow mediated dilation was increased in middle and older aged adults. This indicated the yoga intervention could have benefits for these two groups. J Bodyw Mov Ther PubMed 28167186 10.1016/j.jbmt.2016.06.004 https://pubmed.ncbi.nlm.nih.gov/28167186/
The association between tai chi exercise and safe driving performance among older adults: An observational study Miller S, Taylor-Piliae RE. 2018 Other Linking Intervention and Impact Yes This study looked at the impact of Tai Chi on cognitive and physical function in older adults. Yes No Favorable The study found that the Tai Chi intervention significantly improved in the Driving Scenes Test, maze navigation, Useful Field of View Test, Rapid Walk test, and the Right Foot Tapping Test. J Sport Health Sci PubMed 30356498 10.1016/j.jshs.2017.01.013 https://pubmed.ncbi.nlm.nih.gov/30356498/
Impacts of tai chi exercise on functional fitness in community-dwelling older adults with mild degenerative knee osteoarthritis: A randomized controlled clinical trial Chen PY, Song CY, Yen HY, Lin PC, Chen SR, Lu LH, Tien CL, Wang XM, Lin CH. 2021 Randomized Controlled Trial Linking Intervention and Impact Yes This study looked at the impact of tai chi for community-dwelling older adults with degenerative osteoarthritis in the knee. Yes Favorable The study found the Tai Chi intervention significantly increased functional fitness test scores in the intervention group after the 12-week intervention. BMC Geriatr PubMed 34332537 10.1186/s12877-021-02390-9 https://pubmed.ncbi.nlm.nih.gov/34332537/
Tai chi for chronic obstructive pulmonary disease (COPD) Ngai SP, Jones AY, Tam WW. 2016 Other Linking Intervention and Impact Yes This study looked at the impact of Tai Chi on dyspnoea and exercise in individuals with CPOD. Yes Yes Favorable The review found 12 eligible studies that demonstrated positive impacts of Tai Chi on six-minute walk distance and pulmonary function. Other measures were inconclusive and more research needs to be done. Cochrane Database Syst Rev PubMed 27272131 10.1002/14651858.CD009953.pub2 https://pubmed.ncbi.nlm.nih.gov/27272131/
Effects of yoga-related mind-body therapies on cognitive function in older adults: A systematic review with meta-analysis Bhattacharyya KK, Andel R, Small BJ. 2021 Systematic Review Linking Intervention and Impact Yes This study reviewed current research on the impact of Yoga-related mind-body therapies on cognitive decline in older adults. Yes Favorable The review found 12 eligible studies that demonstrated the yoga intervention had significant positive impact on memory, executive function, and attention and processing speed. Arch Gerontol Geriatr PubMed 33338831 10.1016/j.archger.2020.104319 https://pubmed.ncbi.nlm.nih.gov/33338831/
Effects of exergaming-based tai chi on cognitive function and dual-task gait performance in older adults with mild cognitive impairment: A randomized control trial Liu CL, Cheng FY, Wei MJ, Liao YY. 2022 Randomized Controlled Trial Linking Intervention and Impact Yes This study looked at the impact of two Tai Chi (TC) programs offered in 36 training sessions for 12 weeks on cognitive function and dual-talk walking in older adults with MCI. The two programs were exergaming-based TC (EXER-TC) and Traditional TC (TC) Yes Favorable The study found that the TC intervention and EXER-TC groups both had positive impact on Stroop Color and Word Test, the Trail Making Test Parts A and B, one-back test, gait speed, and dual-task cost of gait speed compared to the control. The EXER-TC group also had positive effect in the Montreal Cognitive Assessment test compared to the control group. Front Aging Neurosci PubMed 35370622 10.3389/fnagi.2022.761053 https://pubmed.ncbi.nlm.nih.gov/35370622/
Benefits of tai chi exercise among adults with chronic heart failure: A systematic review and meta-analysis Taylor-Piliae R, Finley BA. 2020 Systematic Review Linking Intervention and Impact Yes This review looked at current evidence for the impact of Tai Chi on individuals with chronic health failure (CHF). Yes Favorable The review found 6 eligible studies the demonstrated Tai Chi led to significantly better exercise capacity, improved quality of life, decease depression, and decreased b-type natriuretic peptide expression. J Cardiovasc Nurs PubMed 32544110 10.1097/JCN.0000000000000703 https://pubmed.ncbi.nlm.nih.gov/32544110/
The impact of tai chi on cognitive rehabilitation of elder adults with mild cognitive impairment: A systematic review and meta-analysis Wei L, Chai Q, Chen J, Wang Q, Bao Y, Xu W, Ma E. 2022 Systematic Review Linking Intervention and Impact Yes This study looked at current evidence on the impact of Tai Chi on cognitive rehabilitation. The study focused on elderly adults with mild cognitive impairment. Yes Favorable The study found 12 eligible studies that demonstrated the Tai Chi intervention had positive effect on global cognitive ability and long-term delayed recall. It also had a moderate significant impact on improving executive function. Disabil Rehabil PubMed 33043709 10.1080/09638288.2020.1830311 https://pubmed.ncbi.nlm.nih.gov/33043709/
Effects of yoga on psychological health in older adults Bonura KB, Tenenbaum G. 2014 Randomized Controlled Trial Linking Intervention and Impact Yes This study looked at the impact of a yoga intervention for older adults that included chair yoga, chair exercise and control groups. The study looked at how the intervention impacted psychological health. Yes No Favorable The study found that yoga was had significant improvement in participant anger, depression, anxiety, well-being, general self-efficacy, and self-efficacy for daily living than the exercise and control participants. J Phys Act Health PubMed 24366852 10.1123/jpah.2012-0365 https://pubmed.ncbi.nlm.nih.gov/24366852/
Effect of a combined tai chi, resistance training and dietary intervention on cognitive function in obese older women Xu F, Delmonico MJ, Lofgren IE, Uy KM, Maris SA, Quintanilla D, Taetzsch AG, Letendre J, Mahler L. 2017 Other Linking Intervention and Impact Yes This study looked at the impact of Tai Chi combined with resistance training and a diet intervention on cognitive function in a 12-week intervention. The study participants included 25 older, obese women. Yes Favorable The study found the combined intervention let to improved domain specific cognitive function. J Frailty Aging PubMed 28721435 10.14283/jfa.2017.16 https://pubmed.ncbi.nlm.nih.gov/28721435/
Association of tai chi exercise with physical and neurocognitive functions, frailty, quality of life and mortality in older adults: Singapore Longitudinal Ageing Study Lee SY, Nyunt MSZ, Gao Q, Gwee X, Chua DQL, Yap KB, Wee SL, Ng TP. 2022 Prospective Cohort Study Linking Intervention and Impact Yes The study looked at the impact of Tai Chi on physical and cognitive function, frailty, quality of life (QOL) and mortality in community-dwelling adults 55+. Yes Yes (55+) Favorable The study found the Tai Chi intervention was associated with decreased impaired physical QOL, odds of incident prefrailty/frailty, and impaired mental QOL. The mortality risk findings were not significant. Age Ageing PubMed 35380607 10.1093/ageing/afac086 https://pubmed.ncbi.nlm.nih.gov/35380607/
Yoga stretching for improving salivary immune function and mental stress in middle-aged and older adults Eda N, Ito H, Shimizu K, Suzuki S, Lee E, Akama T. 2018 Other Linking Intervention and Impact Yes This study looked at the impact of yoga on mucosal immune function and mental stress in adult women . Yes Yes Favorable The study found that SIgA concentration and secretion rate increased after yoga. Cortisol was lower and testosterone was higher after yoga. J Women Aging PubMed 28368782 10.1080/08952841.2017.1295689 https://pubmed.ncbi.nlm.nih.gov/28368782/
Effect of Yang-style tai chi on gait parameters and musculoskeletal flexibility in healthy Chinese older women Zou L, Wang C, Tian Z, Wang H, Shu Y. 2017 Other Linking Intervention and Impact Yes This study looked at the impact of a Tang-Style Tai Chi intervention in adults 65+. The study looked at the impact on gait parameters and musculoskeletal flexibility. Yes No Favorable The study found the 8-week Tai Chi intervention led to significant improvement in gate parameter, stance phase, gate speed, swing phase, double support time, flexibility-related outcomes, single hip flexor, plantar flexion, range of motion, lateral pelvic tilt, pelvic rotation, hip range of motion, and ankle range of motion. Sports (Basel) PubMed 29910412 10.3390/sports5030052 https://pubmed.ncbi.nlm.nih.gov/29910412/
Meta-analysis of the intervention effects of tai chi on fasting blood glucose, blood pressure and triglyceride in middle-aged and elderly people Zhao W, Ju H, Zhu K. 2024 Other Linking Intervention and Impact Yes This review looked at literature on the impact of Tai Chi on blood pressure, lipid levels, and glucose concentrations for older adults. Yes Favorable The review found 57 eligible studies demonstrating Tai Chi led to improved systolic and diastolic blood pressure, triglyceride, and fasting glucose concentrations in middle-aged and elderly adults. Aging Male PubMed 38259166 10.1080/13685538.2023.2282977 https://pubmed.ncbi.nlm.nih.gov/38259166/
Effects of wheelchair tai chi ball exercise on physical and mental health and functional abilities among elderly with physical disability Wang YT, Goh CH, Liao T, Dong XN, Duke G, Alfred D, Yang Y, Xu J, Yu S. 2021 Other Linking Intervention and Impact Yes This study looked at the impact of a combination intervention of a 12-week Wheelchair Tai Chi Ball (WTCB) with mind-body excise and strength training in elderly adults with disability. The goal was to determine the impact on mental health and functional ability. Yes Favorable The study found the Tai Chi intervention significantly improved Pain Self Efficacy Questionnaire (PSEQ) results, physical health and muscle strength. Res Sports Med PubMed 32546105 10.1080/15438627.2020.1777553 https://pubmed.ncbi.nlm.nih.gov/32546105/
Pilot randomized controlled trial of the yoga for heart intervention in community-dwelling older adults Barrows J, Fleury J. 2022 Randomized Controlled Trial Linking Intervention and Impact Yes This study looked at the impact of a Yoga intervention for older community-dwelling adults on motivation of physical activity. Yes Neutral The study found the Yoga intervention had significant impact on BMI, but had no effect on physical activity and cardiovascular outcomes. Geriatr Nurs PubMed 35217325 10.1016/j.gerinurse.2022.02.003 https://pubmed.ncbi.nlm.nih.gov/35217325/
The effects of different types of tai chi exercise on anxiety and depression in older adults: A systematic review and network meta-analysis Kuang X, Dong Y, Song L, Dong L, Chao G, Zhang X, Yang J. 2024 Systematic Review Linking Intervention and Impact Yes This review looked at evidence of the impact Tai Chi interventions have on anxiety and depression in older adults. Yes The review found 20 eligible studies that demonstrated Tai Chi reduced anxiety and depression compared to control groups. Front Public Health PubMed 38259770 10.3389/fpubh.2023.1295342 https://pubmed.ncbi.nlm.nih.gov/38259770/
Movement-based mind-body practices and cognitive function in middle-aged and older adults: Findings from the Midlife in the United States (MIDUS) study Bhattacharyya KK, Hueluer G, Meng H, Hyer K. 2021 Other Linking Intervention and Impact Yes This study looked at the impact of a movement-based mind-body practice intervention on long-term cognitive health in middle aged and older adults. Yes Yes (25 - 75) Neutral The study found that the Mind-body practice intervention led to a smaller decline in episodic memory, but did not have a significant effect on executive function. Complement Ther Med PubMed 34118391 10.1016/j.ctim.2021.102751 https://pubmed.ncbi.nlm.nih.gov/34118391/
A cluster randomized trial of tai chi vs health education in subsidized housing: The MI-WiSH study Lipsitz LA, Macklin EA, Travison TG, Manor B, Gagnon P, Tsai T, Aizpurúa II, Lo OY, Wayne PM. 2019 Randomized Controlled Trial Linking Intervention and Impact Yes This study looked at the impact of Tai Chi on physical function for older adults. The study specifically looked at older adults living in low-income housing facilities. Yes Yes (60+) Favorable The study found the Tai Chi intervention led to improved Short Physical Performance Battery (SPPB) scores over 12 months. J Am Geriatr Soc PubMed 31116883 10.1111/jgs.15986 https://pubmed.ncbi.nlm.nih.gov/31116883/
The effects of different types of tai chi exercises on motor function in patients with Parkinson's disease: A network meta-analysis Lei H, Ma Z, Tian K, Liu K, Wang J, Zhu X, Mi B, Chen Y, Yang Q, Jiang H. 2022 Meta Analysis Linking Intervention and Impact Yes This study looked at the impact of Tai Chi on balance and motor ability for individuals with Parkinson's The study found that the 24-from Tai Chi and Tai Chi Exercise programs were the most effective interventions. Front Aging Neurosci PubMed 36105909 10.3389/fnagi.2022.936027 https://pubmed.ncbi.nlm.nih.gov/36105909/
Effects of Chinese mind-body exercises on executive function in middle-aged and older adults: A systematic review and meta-analysis Ren FF, Chen FT, Zhou WS, Cho YM, Ho TJ, Hung TM, Chang YK. 2021 Systematic Review Linking Intervention and Impact Yes This study looked at the impact of Chinese mind-body exercises (CMBEs) on executive function (EF) for middle aged and older adults. Yes Yes (50+) Favorable The review found 29 studies that demonstrated CMBEs positively impact overall EF and subdomains of working memory and shifting. Front Psychol PubMed 34093345 10.3389/fpsyg.2021.656141 https://pubmed.ncbi.nlm.nih.gov/34093345/
Functional fitness and fall risk in older adults practitioners or non-practitioners of tai chi Gómez-Campos R, Vidal-Espinoza R, Vega-Novoa S, Silva Ramos de Lázari M, Urzua-Alul L, Portugal MR, De la Torre Choque C, Cossio-Bolaños M. 2023 Other Linking Intervention and Impact Yes This study looked at the impact of Tai Chi on balance, motor function and fear of falling in older adults. Yes Favorable The study found that the Tai Chi intervention improved functional fitness and decreased risk of falling. Eur J Transl Myol PubMed 37199220 10.4081/ejtm.2023.11155 https://pubmed.ncbi.nlm.nih.gov/37199220/
Are yoga and physical activity determinants of quality of life in Polish adults? A cross-sectional study Pluto-Pradzynska A, Pluto-Pradzynska K, Frydrychowicz M, Lagiedo-Zelazowska M, Owoc J, Benjamin S, Au TY, Jaracz K, Dworacki G, Wysocki J, Wasik J. 2022 Other Linking Intervention and Impact Yes This cross-sectional study loos at the impact of yoga on quality of life. Yes Yes (18+) Favorable The study found there was significant increase in QOL associated with the yoga intervention BMJ Open PubMed 36167364 10.1136/bmjopen-2021-059658 https://pubmed.ncbi.nlm.nih.gov/36167364/
Self-management and yoga for older adults with chronic stroke: A mixed-methods study of physical fitness and physical activity Portz JD, Waddington E, Atler KE, Van Puymbroeck M, Schmid AA. 2018 Other Linking Intervention and Impact Yes This study looks at the impact of Yoga on physical fitness in older individuals with chronic stoke. Yes Stroke Favorable The study found that the yoga intervention show significant improvement in endurance, and lower and upper body strength. Clin Gerontol PubMed 28452644 10.1080/07317115.2016.1252453 https://pubmed.ncbi.nlm.nih.gov/28452644/
Mindfulness-based stress reduction and mindfulness-based cognitive therapy with older adults: A qualitative review of randomized controlled outcome research Hazlett-Stevens H, Singer J, Chong A. 2019 Other Linking Intervention and Impact Yes This qualitative review looked at the impact of mindfulness-based stress reduction (MBSR) and Mindfulness-based cognitive therapy (MBCT). Favorable The review found that the MBSR and MBCT interventions are feasible and could have benefits for older adults, but additional research is needed. Clin Gerontol PubMed 30204557 10.1080/07317115.2018.1518282 https://pubmed.ncbi.nlm.nih.gov/30204557/
The effectiveness of dance movement interventions for older adults with mild cognitive impairment, Alzheimer's disease, and dementia: A systematic scoping review and meta-analysis Tao D, Awan-Scully R, Ash GI, Pei Z, Gu Y, Gao Y, Cole A, Baker JS. 2023 Systematic Review Linking Intervention and Impact Yes This study reviewed current research on the impact of dance movement interventions (DMI) for older adults with mild cognitive impairment (MCI, Alzheimer's disease (AD), and dementia. Yes Favorable The study found that there was a significant impact of dance interventions on global cognition, memory, balance, and depression. Ageing Res Rev PubMed 37944706 10.1016/j.arr.2023.102120 https://pubmed.ncbi.nlm.nih.gov/37944706/
The effects of sitting tai chi on physical and psychosocial health outcomes among individuals with impaired physical mobility: A systematic review and meta-analysis Zhao J, Chau JPC, Lo SHS, Choi KC, Liang S. 2021 Systematic Review Linking Intervention and Impact Yes This study looked at the literature on the impact of sitting Tai Chi on different health outcomes for individuals with impaired physical mobility. Favorable The review identified 11 studies that showed significant impact of the sitting Tai Chi intervention on depressive symptoms, heart rate, and social domain of quality of life. Int J Nurs Stud PubMed 33751992 10.1016/j.ijnurstu.2021.103911 https://pubmed.ncbi.nlm.nih.gov/33751992/
Effects of tai chi chuan on cognitive function in older adults with cognitive impairment: A systematic and meta-analytic review Cai Z, Jiang W, Yin J, Chen Z, Wang J, Wang X. 2020 Systematic Review Linking Intervention and Impact Yes This study looked for literature on the impact of Tai Chi Chuan( TCC) on cognitive function in elderly individuals. Yes Favorable The review identified 19 studies that showed significant impact on cognitive function. Evid Based Complement Alternat Med PubMed 33424991 10.1155/2020/6683302 https://pubmed.ncbi.nlm.nih.gov/33424991/
Effects of nonpharmacological interventions for dizziness in older people: Systematic review Kendall JC, Hartvigsen J, Azari MF, French SD. 2016 Systematic Review Linking Intervention and Impact Yes The study identified research looking at the impact of nonpharmacological interventions on dizziness in older people. Yes Neutral The review found 7 studies, but found insufficient evidence Phys Ther PubMed 26450972 10.2522/ptj.20150349 https://pubmed.ncbi.nlm.nih.gov/26450972/
Effects of tai chi on cerebral hemodynamics and health-related outcomes in older community adults at risk of ischemic stroke: A randomized controlled trial Zheng G, Zheng X, Li J, Duan T, Ling K, Tao J, Chen L. 2019 Randomized Controlled Trial Linking Intervention and Impact Yes This study looked at the impact of Tai Chi on adults at risk of ischemic stroke. Favorable The study found the intervention had significant improvement on the minimum of blood flow velocity after 12 weeks. J Aging Phys Act PubMed 30747548 10.1123/japa.2018-0232 https://pubmed.ncbi.nlm.nih.gov/30747548/
Yoga to prevent mobility limitations in older adults: Feasibility of a randomized controlled trial Groessl EJ, Maiya M, Schmalzl L, Wing D, Jeste DV. 2018 Other Linking Intervention and Impact Yes This study aimed to understand the feasibility and safety of a yoga intervention for older adults at risk of mobility limitations. Yes The study found high 10-week follow-up and attendance of participants. There were no serious adverse events and they determined the study was feasible and could be conducted as a larger RCT. BMC Geriatr PubMed 30541474 10.1186/s12877-018-0988-8 https://bmcgeriatr.biomedcentral.com/articles/10.1186/s12877-018-0988-8
Tai chi improves cognition and plasma BDNF in older adults with mild cognitive impairment: A randomized controlled trial Sungkarat S, Boripuntakul S, Kumfu S, Lord SR, Chattipakorn N. 2018 Randomized Controlled Trial Linking Intervention and Impact Yes This study analyzed the impact of Tai Chi on cognitive function. Yes Favorable The study found the Tai Chi intervention significantly improved logical memory and trial making test B minus A (TMT B-A). The TC group also had significantly increased plasma BDNF levels. Neurorehabil Neural Repair PubMed 29353543 10.1177/1545968317753682 https://pubmed.ncbi.nlm.nih.gov/29353543/
Tai chi training's effect on lower extremity muscle co-contraction during single- and dual-task gait: Cross-sectional and randomized trial studies Wayne PM, Gow BJ, Hou F, Ma Y, Hausdorff JM, Lo J, Rist PM, Peng CK, Lipsitz LA, Novak V, Manor B. 2021 Other Linking Intervention and Impact Yes This cross-sectional and randomized trial looked at the impact of Tai Chi on falls, balance, gait in health adults. Favorable The study found that higher co-contraction index (CCI) scores were correlated with slower gait speed in cognitive dual-task conditions. It showed that Tai Chi experts had lower CCI than Tai Chi naïve participants. PLoS One PubMed 33481829 10.1371/journal.pone.0242963 https://pubmed.ncbi.nlm.nih.gov/33481829/
Benefits of Thai yoga on physical mobility and lower limb muscle strength in overweight/obese older women: A randomized controlled pilot trial Widjaja W, Wongwattanapong T, Laskin JJ, Ajjimaporn A. 2021 Randomized Controlled Trial Linking Intervention and Impact Yes This study looked at the impact of Thai Yoga on fitness measures in elderly, overweight/obese women. Yes (62 +/- 1 year) Favorable The study found that the Thai Yoga intervention showed significant improvement in all fitness measures compared to the control group. Complement Ther Clin Pract PubMed 33706066 10.1016/j.ctcp.2021.101345 https://pubmed.ncbi.nlm.nih.gov/33706066/
Yoga, health-related quality of life and mental well-being: A re-analysis of a meta-analysis using the quality effects model Kelley GA, Kelley KS. 2020 Meta Analysis Linking Intervention and Impact Yes This study looked a the impact of Yoga on mental well-being (MWB) and health-related quality-of-life (HRQOL) in older adults. Yes Yes (60+) Favorable The study found the Yoga intervention significantly improved HRQOL and MWB. J Gerontol A Biol Sci Med Sci PubMed 31814012 10.1093/gerona/glz284 https://pubmed.ncbi.nlm.nih.gov/31814012/
Effect of laughter therapy on depression and quality of life of the elderly living in nursing homes Heidari M, Ghodusi Borujeni M, Rezaei P, Kabirian Abyaneh S, Heidari K. 2020 Other Linking Intervention and Impact Yes This study looked at the impact of Laughter Therapy (LT) on depression and quality of life (QOL) in older individuals. Yes Yes (60-69) Favorable The study found that the intervention led to decreased depression. Malays J Med Sci PubMed 32863751 10.21315/mjms2020.27.4.11 https://pubmed.ncbi.nlm.nih.gov/32863751/
Effectiveness of yoga versus exercise for reducing falling risk in older adults: Physical and psychological indices Bartos LJ, Meek GA, Berger BG. 2022 Other Linking Intervention and Impact Yes This study analyzed the impact of Yoga on falling in older adults by comparing participants in a yoga program, exercise program, and control group with no program. Yes No Favorable The study found that the Yoga participants scored higher on lower extremity flexibility than the exercise program participants, and might be at less risk of falling. Percept Mot Skills PubMed 35613041 10.1177/00315125221100820 https://pubmed.ncbi.nlm.nih.gov/35613041/
Effectiveness of tai chi on quality of life, depressive symptoms and physical function among community-dwelling older adults with chronic disease: A systematic review and meta-analysis Choo YT, Jiang Y, Hong J, Wang W. 2020 Systematic Review Linking Intervention and Impact Yes This study looked at current literature on the impact of Tai Chi on quality of life (QOL), depressive symptoms and physical function in older adults living in the community with chronic disease. Yes Favorable The review found 13 eligible studies that indicated a small positive impact of Tai Chi on QOL and depressive symptoms. Int J Nurs Stud PubMed 32891966 10.1016/j.ijnurstu.2020.103737 https://pubmed.ncbi.nlm.nih.gov/32891966/
Feasibility and effects of a chair-based yoga program for adults with neurodisability Suárez-Iglesias D, García-Porro M, Clardy A, Ayán Pérez C. 2022 Other Linking Intervention and Impact Yes This study looked at the feasibility of a 10-week chair-based yoga intervention for adults with neutralizability and moderate to severe physical dependence. No Yes Favorable The study showed the intervention was feasible. IT found that their was a significant positive effect on body awareness, emotional awareness, and trusting. There was not significant impact on HRQoL. Disabil Rehabil PubMed 34100670 10.1080/09638288.2021.1933617 https://pubmed.ncbi.nlm.nih.gov/34100670/
The potential advantages of tai chi chuan in promoting inhibitory control and spontaneous neural activity in young adults Shen QQ, Yin HC, Cui L, Zhang JY, Wang DL, Zhu LN, Wang Y, Li XJ. 2021 Other Linking Intervention and Impact Yes This study looked at the impact of an 8-week Tai Chi Chuan (TCC) intervention on functional brain activity and cognitive function in young adults. No Yes Favorable The study found that TCC had a positive correlation with processing efficiency. Front Behav Neurosci PubMed 34803624 10.3389/fnbeh.2021.747733 https://pubmed.ncbi.nlm.nih.gov/34803624/
Tai chi improves cognitive and physical function in the elderly: A randomized controlled trial Sun J, Kanagawa K, Sasaki J, Ooki S, Xu H, Wang L. 2015 Randomized Controlled Trial Linking Intervention and Impact Yes This study analyzed the impact of Tai Chi for a 6 month period on physical function in elderly individuals yes Favorable The study found mixed results with no significant difference between groups for one let standing time with eyes open, left grip strength or frontal assessment battery. The study found higher Mini-Mental State Examinations scores in the Tai Chi group after 3 and 6 months and increased right grip strength. There was a significant decrease in 5m high walking speed and 10m normal walking speed in the Tai Chi Group. J Phys Ther Sci PubMed 26157242 10.1589/jpts.27.1467 https://pubmed.ncbi.nlm.nih.gov/26157242/
Effects of tai chi and qigong on cognitive and physical functions in older adults: Systematic review, meta-analysis, and meta-regression of randomized clinical trials Park M, Song R, Ju K, Shin JC, Seo J, Fan X, Gao X, Ryu A, Li Y. 2023 Meta Analysis Linking Intervention and Impact Yes This study looks at existing studies showing the impact of Tai Chi and Qigong interventions on cognitive and physical function in older adults Yes Favorable This study found 17 studies that demonstrated a significant positive impact on cognitive and physical function from Tai Chi and Qigong BMC Geriatr PubMed 37280512 10.1186/s12877-023-04070-2 https://pubmed.ncbi.nlm.nih.gov/37280512/
Effects of 12-week tai chi program on physical function, depression, and quality of life among cognitively impaired older adults: A feasibility study Oh H, Song R, Kim SJ. 2023 Other Linking Intervention and Impact Yes This study uses a quasi-experimental design to look at the impact and feasibility of a Tai Chi intervention on older adults with mild cognitive impairment (MCI) or dementia. Yes Dementia Favorable This study found that Tai chi significantly improved right-hand grip strength and physical-health-related QoL in individuals with MCI. TUG scores significantly improved in both MCI and dementia groups. BMC Geriatr PubMed 36869290 10.1186/s12877-023-03840-2 https://pubmed.ncbi.nlm.nih.gov/36869290/
The effect of web-based hatha yoga on psychological distress and sleep quality in older adults: A randomized controlled trial Baklouti S, Fekih-Romdhane F, Guelmami N, Bonsaksen T, Baklouti H, Aloui A, Masmoudi L, Souissi N, Jarraya M. 2023 Randomized Controlled Trial Linking Intervention and Impact Yes This study analyzed the impact of an 8-week online Hatha yoga intervention on the psychological and quality of sleep of older adults Yes Mental Health Favorable The study showed that the Yoga intervention significantly decreased depression, anxiety, and stress. The study also found that the PSQI score related to the quality of sleep significantly improved in the intervention group. Complement Ther Clin Pract PubMed 36521407 10.1016/j.ctcp.2022.101715 https://pubmed.ncbi.nlm.nih.gov/36521407/
Effect of tai chi on muscle strength of the lower extremities in the elderly Zhou M, Peng N, Dai Q, Li HW, Shi RG, Huang W. 2016 Other Linking Gap and Impact Yes This cross-sectional study looked at the long term impact of Tai Chi over a 6-12 month period on muscle strength. Yes yes Favorable The study found increased strength in the intervention group but the strength did not differ between age groups. Chin J Integr Med PubMed 26015074 10.1007/s11655-015-2104-7 https://pubmed.ncbi.nlm.nih.gov/26015074/
Effects of yoga on physical and psychological health among community-dwelling older adults: A systematic review and meta-analysis Ko KY, Kwok ZCM, Chan HY. 2023 Systematic Review Linking Intervention and Impact Yes This study looked at the existing literature on the impact of yoga on physical and psychological outcomes in adults 60+. Yes Yes Favorable The review found significant improvement in balance, flexibility, muscle strength, and depressive symptoms from Yoga. It also found that yoga decreased anxiety. There were inconclusive results on the impact on gait and other psychological outcomes. Int J Older People Nurs PubMed 37577926 10.1111/opn.12562 https://pubmed.ncbi.nlm.nih.gov/37577926/
The effect of tai chi chuan on negative emotions in non-clinical populations: A meta-analysis and systematic review Zhang S, Zou L, Chen LZ, Yao Y, Loprinzi PD, Siu PM, Wei GX. 2019 Systematic Review Linking Intervention and Impact Yes This study looked at a Tai Chi Chuan intervention and its impact on negative emotions such as anxiety and depression. Mental Health Favorable The study found 14 studies that demonstrated the intervention had a positive impact on negative emotions. They also found that older adults benefit more from the intervention than young adults. Int J Environ Res Public Health PubMed 31438638 10.3390/ijerph16173033 https://pubmed.ncbi.nlm.nih.gov/31438638/
Clinical relevance of tai chi on pain and physical function in adults with knee osteoarthritis: An ancillary meta-analysis of randomized controlled trials Kelley GA, Kelley KS, Callahan LF. 2022 Meta Analysis Linking Intervention and Impact Yes This study looked at the impact of Tai Chi in older adults with knee osteoarthritis. Yes Yes (18+) Favorable The study found that Tai Chi had significant positive effects on pain, stiffness, and physical function. Sci Prog PubMed 35379041 10.1177/00368504221088375 https://pubmed.ncbi.nlm.nih.gov/35379041/
Tai chi exercise for psychological well-being among adults with cardiovascular disease: A systematic review and meta-analysis Taylor-Piliae RE, Finley BA. 2020 Systematic Review Linking Intervention and Impact Yes This study looks at the impact of a Tai Chi intervention on the psychological well-being of individuals with cardiovascular disease. Cardiovascular Disorders Favorable The review found 15 studies that demonstrated the intervention significantly improved general QOL, mental health QOL, physical health QOL, depression and phycological distress. Eur J Cardiovasc Nurs PubMed 32515204 10.1177/1474515120926068 https://pubmed.ncbi.nlm.nih.gov/32515204/
The effect of tai chi exercise on postural time-to-contact in manual fitting task among older adults Pan J, Liu C, Li L, Zhang S. 2020 Other Linking Intervention and Impact Yes This study looked at the impact of a Tai Chi intervention on postural time to contact. This was measured by having participants fit a block through two different openings/distances. Yes Favorable The study found that those in the Tai Chi group had significantly longer postural time to contact than those who were not. Gait Posture PubMed 32896796 10.1016/j.gaitpost.2020.08.124 https://pubmed.ncbi.nlm.nih.gov/32896796/
Relationship between falls and complementary and alternative medicine use among community-dwelling older adults Caron A, Gallo WT, Durbin LL, Mielenz TJ. 2017 Other Linking Intervention and Impact Yes This cross-sectional study looked at how complementary and alternative medicine (CAM) impacted falls in older adults. The CAM interventions included alternative medical systems, biologically based therapies, manipulative and body-based therapies, mind-body therapies, and movement therapies Yes Yes (60+) Unfavorable The study found that individuals that had tried manipulative and body-based therapies had a higher likelihood of falling. The study noted this could be due to this group seeking therapy for chronic pain. There were no other significant findings. J Altern Complement Med PubMed 27967210 10.1089/acm.2016.0095 https://pubmed.ncbi.nlm.nih.gov/27967210/
Tai chi combined with resistance training for adults aged 50 years and older: A systematic review Qi M, Moyle W, Jones C, Weeks B. 2020 Systematic Review Linking Intervention and Impact Yes This study looked a the impact of Tai Chi on health promotion in older adults (50+) Yes Yes (50+) Favorable The review found 7 studies that met the criteria. The studies demonstrated that Tai Chi significantly improved upper and lower extremity muscle strength, aerobic endurance, balance, and mobility. J Geriatr Phys Ther PubMed 30531200 10.1519/JPT.0000000000000218 https://pubmed.ncbi.nlm.nih.gov/30531200/
Dose-response association of tai chi and cognition among community-dwelling older adults: A systematic review and meta-analysis Chen ML, Wotiz SB, Banks SM, Connors SA, Shi Y. 2021 Systematic Review Linking Intervention and Impact Yes This study looked at the impact of Tai Chi on cognitive impairment in older adults. Yes Favorable This review found 16 studies that demonstrated Tai Chi had positive impact on cognitive function, but not on dose duration effects on cognition. Int J Environ Res Public Health PubMed 33808633 10.3390/ijerph18063179 https://pubmed.ncbi.nlm.nih.gov/33808633/
Tai chi practice on prefrontal oxygenation levels in older adults: A pilot study Tsang WWN, Chan KK, Cheng CN, Hu FSF, Mak CTK, Wong JWC. 2019 Other Linking Intervention and Impact Yes This study looked at the impact of Tai Chi on cognitive function. The study included Tai Chi for mind-body exercise and arm ergometry that was a body focused exercise. Yes Favorable This study found that the Tai Chi intervention significantly changed the levels of oxyhemoglobin and total hemoglobin for the Tai Chi group. The study found that brain activity was higher in the TC group versus the AE group. Complement Ther Med PubMed 30670231 10.1016/j.ctim.2018.11.005 https://pubmed.ncbi.nlm.nih.gov/30670231/
Effects of wheelchair tai chi on physical and mental health among elderly with disability Wang YT, Li Z, Yang Y, Zhong Y, Lee SY, Chen S, Chen YP. 2016 Other Linking Intervention and Impact Yes This study analyzed the impact of a 12-week Wheelchair Tai Chi From Intervention on physical and mental health measures in older adults with disability. Yes Favorable The study found the intervention showed significant improvement in systolic and diastolic blood pressure, shoulder external rotation, left trunk rotation, and total trunk rotation. Res Sports Med PubMed 27248716 10.1080/15438627.2016.1191487 https://pubmed.ncbi.nlm.nih.gov/27248716/
Complementary health approaches for health and wellness in midlife and older us adults Johnson PJ, Jou J, Rhee TG, Rockwood TH, Upchurch DM. 2016 Other Linking Intervention and Impact Yes This study looked at 2012 National Health Interview Survey data to understand the impact of complementary health approaches (CHA) on midlife and older adults. Yes Yes (50+) Favorable The study found that individuals using wellness-only and combined treatment had significantly higher odds of reporting benefits than treatment only users. Maturitas PubMed 27180158 10.1016/j.maturitas.2016.04.012 https://pubmed.ncbi.nlm.nih.gov/27180158/
Effect of tai chi and resistance training on cancer-related fatigue and quality of life in middle-aged and elderly cancer patients Cheng D, Wang X, Hu J, Dai LL, Lv Y, Feng H, Zhang Y, Guo Y, Wang L. 2021 Other Linking Intervention and Impact Yes This study looks at the impact of Tai Chi (TC) and Resistance training (RT) on cancer-related fatigue and quality of life for middle-aged and elderly cancer patients. The TC group had sessions 40 minutes per day, 3 days a week, for 12 weeks. The RT group had 10 sessions, 6 designated movements per day, 3 days a week for 12 weeks. Yes Yes Cancer Favorable The study found that the 12-week intervention had significant improvement in cancer-related fatigue (CRF) and quality of life (QoL) in both the TC and RT groups. The TC group also showed significant improvement in lower limb muscle strength and GAD-7, PHQ-9, and PSQI scores compared to the RT groups. Chin J Integr Med PubMed 33420583 10.1007/s11655-021-3278-9 https://pubmed.ncbi.nlm.nih.gov/33420583/
Yoga therapy on elderly patients with fear of fall: An open-label randomised controlled trial (YOFEAR trial) Kashyap K, Dhar M, Bisht K, Bahurupi Y, Pathania M. 2023 Randomized Controlled Trial Linking Intervention and Impact Yes The study aimed to understand the impact of Yoga on the fear of falling in older adults. Yes Yes (60+) Neutral The study reports the design but does not currently have the findings. BMJ Open PubMed 38151281 10.1136/bmjopen-2022-070540 https://pubmed.ncbi.nlm.nih.gov/38151281/
Effects of yoga and aerobic exercise on wellbeing in physically inactive older adults: Randomized controlled trial (FitForAge) Welford P, Östh J, Hoy S, Diwan V, Hallgren M. 2022 Randomized Controlled Trial Linking Intervention and Impact Yes This study looked at the impact of yoga and aerobic exercise (AE) in older adults that are physically inactive. Yes Favorable The study found that both yoga and AE shooed a positive impact on well-being. Yoga was found to be associated with fewer adverse events. Complement Ther Med PubMed 35143970 10.1016/j.ctim.2022.102815 https://pubmed.ncbi.nlm.nih.gov/35143970/
Role of yoga therapy in improving digestive health and quality of sleep in an elderly population: A randomized controlled trial Shree Ganesh HR, Subramanya P, Rao M R, Udupa V. 2021 Randomized Controlled Trial Linking Intervention and Impact Yes This study looked at the impact of Yoga over a 3 month intervention on the sleep and constipation related quality of life (QOL) in older women Yes Yes (60+) Favorable The study found that the yoga intervention significantly improved sleep quality and constipation related QOL. J Bodyw Mov Ther PubMed 34391308 10.1016/j.jbmt.2021.04.012 https://pubmed.ncbi.nlm.nih.gov/34391308/
The mental-attention tai chi effect with older adults Kim TH, Pascual-Leone J, Johnson J, Tamim H. 2016 Randomized Controlled Trial Linking Intervention and Impact Yes The study looked at the impact of a 16-week Tai Chi intervention on specific mental-attentional executive processes Yes Yes (51-87) Favorable The study found that the Tai Chi group had significant gain on Figural Intersections Task (mental-attentional capacity), Antisaccade (attentional inhibition), and Matrix Reasoning (fluid intelligence measure). It also found that both interventions improved Water Level Task (attentional balance). BMC Psychol PubMed 27245444 10.1186/s40359-016-0137-0 https://pubmed.ncbi.nlm.nih.gov/27245444/
Effect of tai chi on depression symptoms and sleep quality among older adult women after exercise cessation Cheng L, Qian L, Chang S, He B. 2021 Yes The study looked at the impact of a 24 week Tai Chi intervention on the psychological health and sleep quality of older adult women. Favorable Tai Chi had a positive effect on fatigue, depression, vigor, and sleep quality on older adult women. The effect on depression and sleep quality lasted 4 weeks after the intervention stopped Res Sports Med PubMed 33401978 10.1080/15438627.2020.1870976 https://pubmed.ncbi.nlm.nih.gov/33401978/
Can tai chi improve cognitive function? A systematic review and meta-analysis of randomized controlled trials Liu F, Chen X, Nie P, Lin S, Guo J, Chen J, Yu L. 2021 Systematic Review Linking Intervention and Impact Yes The review looked at literature on the impact of Tai Chi intervention among different populations' cognitive function improvement. Favorable The review found 33 studies demonstrating Tai Chi could improve cognitive function in middle-aged and elderly people with cognitive impairment and older adults and college students J Altern Complement Med PubMed ` 10.1089/acm.2021.0084 https://pubmed.ncbi.nlm.nih.gov/34314596/
The effectiveness of tai chi for knee osteoarthritis: An overview of systematic reviews Ye Y, Liu A. 2023 Systematic Review Linking Intervention and Impact Yes This review looked at literature on the impact of Tai Chi for Knee Osteoarthritis in older individuals. Neutral The review found six eligibility studies that demonstrated Tai Chi is effective in the integrative treatment of KOA but does not have enough quality of evidence. Int J Gen Med PubMed 37814642 10.2147/IJGM.S434800 https://pubmed.ncbi.nlm.nih.gov/37814642/
A systematic review of the effects of aromatherapy with lavender essential oil on depression Jafari-Koulaee A, Elyasi F, Taraghi Z, Sadat Ilali E, Moosazadeh M. 2020 Systematic Review Linking Intervention and Impact Yes This review found literature on the impact of aromatherapy with lavender essential oil on depression. Neutral The review found 9 eligible studies with mixed results. Some studies showed positive effects of aromatherapy with lavender essential oil on depression and some reported no significant effect. Cent Asian J Glob Health PubMed 35866093 10.5195/cajgh.2020.442 https://pubmed.ncbi.nlm.nih.gov/35866093/
Mind-body therapies for older adults with dementia: A systematic review and meta-analysis Wang Y, Tang C, Fan X, Shirai K, Dong JY. 2022 Systematic Review Linking Intervention and Impact Yes This review found literature on the impact of mind-body therapies (MBTs) on older adults with dementia Yes Yes (60+) Dementia Favorable The review found 9 eligible studies demonstrating that MBTs could improve some health outcomes among older populations with dementia Eur Geriatr Med PubMed 35377128 10.1007/s41999-022-00639-z https://pubmed.ncbi.nlm.nih.gov/35377128/
A comparison of two tai chi interventions tailored for different health outcomes Wu Y, Senk C, Coll P, Glenney S, Zaborowski K, Fortinsky R, Taylor B, Park C, Benson K, McGowan M, DiBiasi S, Chen MH, Pescatello L. 2021 Randomized Controlled Trial Linking Intervention and Impact Yes This study looked at the impact of two Tai Chi interventions (PRESSURE and BALANCE) that aimed to improve blood pressure or balance. Yes Yes (60+) Favorable PRESSURE significantly improved chair sit-to-stand (CSTS) test and gait speed compared to the control. BALANCE significantly improved single let stance test and CSTS and tended to lower SBP compared to the control group. Complement Ther Med PubMed 33989797 10.1016/j.ctim.2021.102731 https://pubmed.ncbi.nlm.nih.gov/33989797/
Patient's and health care provider's perspectives on music therapy in palliative care - an integrative review Schmid W, Rosland JH, von Hofacker S, Hunskår I, Bruvik F. 2018 Systematic Review Linking Intervention and Impact Yes This study aimed to understand providers' and users' perspective on music therapy in palliative care Favorable The review found 12 eligible studies that showed positive changes in psycho-physiological well-being from both quantitative and qualitative research. BMC Palliat Care PubMed 29463240 10.1186/s12904-018-0286-4 https://pubmed.ncbi.nlm.nih.gov/29463240/
Balance and functional training and health in adults: An overview of systematic reviews McLaughlin EC, El-Kotob R, Chaput JP, Janssen I, Kho ME, Poitras VJ, Ross R, Ross-White A, Saunders TJ, Sherrington C, Giangregorio LM. 2020 Systematic Review Linking Intervention and Impact Yes This review looked at literature on the effect of balance and functional strength training on health outcomes. Yes Yes (18+) Favorable The review found 5 eligible studies that demonstrated a positive impact from balance and functional training on reduced falls and improved health outcomes. The studies all focused on adults 65 and older. Appl Physiol Nutr Metab PubMed 33054334 10.1139/apnm-2020-0279 https://pubmed.ncbi.nlm.nih.gov/33054334/
Comparing cognitive behavioral therapy versus yoga for helping older adults address high levels of worry Brenes GA, Danhauer SC, Divers J, Miller ME. 2021 Other Linking Intervention and Impact Yes This study looked at the impact of cognitive behavioral therapy (CBT) and yoga on worry. Yes Yes (60+) Favorable Both CBT and yoga led to decrease in worry and anxiety symptom. CBT improved sleep more than Yoga. Comparing Cognitive Behavioral Therapy versus Yoga for Helping Older Adults Address High Levels of Worry PubMed 38237006 10.25302/03.2021.CER.151133007 https://pubmed.ncbi.nlm.nih.gov/38237006/
Long-term tai chi practice in older adults is associated with "younger" functional abilities Ma Y, Gow BJ, Song R, Rist PM, Hausdorff JM, Lipsitz LA, Manor B, Wayne PM. 2024 Other Linking Intervention and Impact Yes This study looked at the impact of both long-term and short-term Tai Chi (TC) training on age-related decline in physical function in healthy older adults. Yes Yes (average = 64.2) Favorable The study found that long term TC training improved physical function in older adults, but the short term impact was not significant. The study found that more research will be needed. Aging Cell PubMed 37905388 10.1111/acel.14023 https://pubmed.ncbi.nlm.nih.gov/37905388/
Yoga-based exercise improves balance and mobility in people aged 60 and over: A systematic review and meta-analysis Youkhana S, Dean CM, Wolff M, Sherrington C, Tiedemann A. 2016 Systematic Review Linking Intervention and Impact Yes This review found literature looking at the impact of a yoga-based exercise intervention on balance and physical mobility. Yes Yes (60+) Favorable This review identified 6 eligible studies that showed small improvements in balance and medium improvements in physical mobility. Age Ageing PubMed 26707903 10.1093/ageing/afv175 https://pubmed.ncbi.nlm.nih.gov/26707903/
Effect of complementary therapies on functional capacity and quality of life among prefrail and frail older adults: A systematic review of randomized controlled trials Buto MSS, de Oliveira MPB, Carvalho C, Vassimon-Barroso V, Takahashi ACM. 2020 Systematic Review Linking Intervention and Impact Yes This review found literature on the impact of complementary therapies on prefrail and frail older adults. Tai Chi was the therapy with the main findings. Yes Favorable The review identified 15 eligible studies that demonstrated Tai Chi could improve functional capacity and quality of life. Arch Gerontol Geriatr PubMed 32860990 10.1016/j.archger.2020.104236 https://pubmed.ncbi.nlm.nih.gov/32860990/
Tai chi practice enables prefrontal cortex bilateral activation and gait performance prioritization during dual-task negotiating obstacle in older adults Chen Y, Wan A, Mao M, Sun W, Song Q, Mao D. 2022 Other Linking Intervention and Impact Yes This study looked at the impact of Tai Chi on cognitive function of the prefrontal cortex in a 16 week intervention. Yes Favorable The study found the Tai Chi intervention led to improved cognitive resources. Front Aging Neurosci PubMed 36466597 10.3389/fnagi.2022.1000427 https://pubmed.ncbi.nlm.nih.gov/36466597/
Effect of different types of tai chi exercise programs on the rate of change in bone mineral density in middle-aged adults at risk of osteoporosis: A randomized controlled trial Kong J, Tian C, Zhu L. 2023 Randomized Controlled Trial Linking Intervention and Impact Yes This study looked a the impact of a 16-week Tai Chi intervention on bone mineral density (BMD). The target population was elderly individuals with osteoporosis (OP) Yes Favorable The study found the Tai Chi intervention led to significant improvement sin BMD. J Orthop Surg Res PubMed 38072989 10.1186/s13018-023-04324-0 https://pubmed.ncbi.nlm.nih.gov/38072989/
Impact of yoga on cognition and mental health among elderly: A systematic review Chobe S, Chobe M, Metri K, Patra SK, Nagaratna R. 2020 Systematic Review Linking Intervention and Impact Yes The study looked at the impact of Yoga on cognitive and mental health in elderly individuals. Yes Yes Mental Health Favorable The review found 13 RCTs and found that the yoga intervention had positive impacts on attention, executive functions among cognitive variables and depression in elderly individuals. Complement Ther Med PubMed 32951703 10.1016/j.ctim.2020.102421 https://pubmed.ncbi.nlm.nih.gov/32951703/
Tai chi for spatiotemporal gait features and dynamic balancing capacity in elderly female patients with non-specific low back pain: A six-week randomized controlled trial Yan ZW, Yang Z, Yang J, Chen YF, Zhang XB, Song CL. 2022 Randomized Controlled Trial Linking Intervention and Impact Yes This study analyzed the impact of Tai Chi on the gait and dynamic balance of elderly women. The intervention included Tai Chi 3 times a week for 6 weeks in 60 minute sessions. Yes Favorable The study found that the Tai Chi intervention significantly decreased VAS, stride width, gait velocity, stride length J Back Musculoskelet Rehabil PubMed 35599469 10.3233/BMR-210247 https://pubmed.ncbi.nlm.nih.gov/35599469/
The effect of modified tai chi exercises on the physical function and quality of life in elderly women with knee osteoarthritis Song J, Wei L, Cheng K, Lin Q, Xia P, Wang X, Wang X, Yang T, Chen B, Ding A, Sun M, Chen A, Li X. 2022 Randomized Controlled Trial Linking Intervention and Impact Yes This study looks at the impact of Tai Chi on Knee osteoarthritis (KOA) in elderly women. Yes Favorable The study found that the Tai Chi intervention significantly improved pain, stiffness, and physical function using the Western Ontario and McMaster university Osteoarthritis Index (WOMAC) measure. Front Aging Neurosci PubMed 35721018 10.3389/fnagi.2022.860762 https://pubmed.ncbi.nlm.nih.gov/35721018/
Meta-analysis of the effect of yoga practice on physical fitness in the elderly Shin S. 2021 Meta Analysis Linking Intervention and Impact Yes This study looks at the impact of a yoga intervention for 9-12 weeks on physical fitness of elderly individuals in their 60s and 70s. Yes Yes Favorable The study found that the yoga intervention had a positive effect on muscle strength, balance, and flexibility. Int J Environ Res Public Health PubMed 34770176 10.3390/ijerph182111663 https://pubmed.ncbi.nlm.nih.gov/34770176/
The effect of tai chi in elderly individuals with sarcopenia and frailty: A systematic review and meta-analysis of randomized controlled trials Huang CY, Mayer PK, Wu MY, Liu DH, Wu PC, Yen HR. 2022 Systematic Review Linking Intervention and Impact Yes This review found literature on the impact of Tai Chi on muscle mass, strength, and physical function. The target population included elderly individuals with sarcopenia and frailty. Yes Yes (60+) Favorable The review found 11 eligible studies that demonstrated significant benefit from Tai Chi on 30-second chair and stand test, timed up and go test, number of falls, and fear of falling. No effect was found on muscle mass, grip strength, gait speed, or Short Physical Performance Battery Scores. Ageing Res Rev PubMed 36223875 10.1016/j.arr.2022.101747 https://pubmed.ncbi.nlm.nih.gov/36223875/
Laughter-inducing therapies: Systematic review and meta-analysis van der Wal CN, Kok RN. 2019 Systematic Review Linking Intervention and Impact Yes The review found literature on the impact of laughter inducing therapies on mental and physical health. Favorable Laughter-inducing therapies were shown to improve depression, but the study quality was low and had a substantial risk of bias. Soc Sci Med PubMed 31029483 10.1016/j.socscimed.2019.02.018 https://pubmed.ncbi.nlm.nih.gov/31029483/
Effects of tai chi chuan on cognitive function in adults 60 years or older with type 2 diabetes and mild cognitive impairment in China: A randomized clinical trial Chen Y, Qin J, Tao L, Liu Z, Huang J, Liu W, Xu Y, Tang Q, Liu Y, Chen Z, Chen S, Liang S, Chen C, Xie J, Liu J, Chen L, Tao J. 2023 Randomized Controlled Trial Linking Intervention and Impact Yes This study looked at the impact of Tai Chi Chuan and fitness walking for cognitive function. The study had a target population of individuals with T2D and mild cognitive impairment (MCI). Yes Yes (60+) Diabetes Alochol/Drug Dependence Favorable The study found that Tai chi Chuan improved Montreal Cognitive Assessment (MoCA) scores after 36 weeks. The study found that Tai Chi had more of an impact on global cognitive function than fitness walking. JAMA Netw Open PubMed 37022680 10.1001/jamanetworkopen.2023.7004 https://pubmed.ncbi.nlm.nih.gov/37022680/
Effect of yoga on frailty in older adults: A systematic review Loewenthal J, Innes KE, Mitzner M, Mita C, Orkaby AR. 2023 Systematic Review Linking Intervention and Impact Yes This review found literature on the impact of a yoga-based interventions on frailty in older adults. Yes Favorable The review identified 22 studies that demonstrated Yoga had positive impact on frailty markers, but might not be more effective than other active interventions. Ann Intern Med PubMed 36913687 10.7326/M22-2553 https://pubmed.ncbi.nlm.nih.gov/36913687/
Aromatherapy for dementia Ball EL, Owen-Booth B, Gray A, Shenkin SD, Hewitt J, McCleery J. 2020 Systematic Review Linking Intervention and Impact Yes The review looked literature on the impact of aromatherapy interventions on individuals with dementia in a Neutral The review identified 13 eligible studies, but no benefit was found from aromatherapy. Cochrane Database Syst Rev PubMed 32813272 10.1002/14651858.CD003150.pub3 https://pubmed.ncbi.nlm.nih.gov/32813272/
Effects of fitness qigong and tai chi on middle-aged and elderly patients with type 2 diabetes mellitus Li X, Si H, Chen Y, Li S, Yin N, Wang Z. 2020 Other Linking Intervention and Impact Yes The study looked at the impact of 12 weeks of qigong and tai chi for middle-aged and older adults with T2DM. Yes Yes Diabetes Favorable Outcomes included fasting plasma glucose (FpG), glycated hemoglobin (HbA1C),and C-peptide (C-P) levels. There was significant influence on HbA1C and C-P levels. Study found qigong intervention could have more impact on patients with longer duration of T2DM and Tai Chi could be risky for people with central obesity. PLoS One PubMed 33332396 10.1371/journal.pone.0243989 https://pubmed.ncbi.nlm.nih.gov/33332396/
Effects of tai chi or conventional exercise on central obesity in middle-aged and older adults: A three-group randomized controlled trial Siu PM, Yu AP, Chin EC, Yu DS, Hui SS, Woo J, Fong DY, Wei GX, Irwin MR. 2021 Randomized Controlled Trial Linking Intervention and Impact Yes The study looked at the impact of a Tai Chi intervention for management of central obesity. Yes Yes (50+) Favorable Primary outcome: waist circumference (WC) Secondary outcomes: body weight; body mass index; high-density lipoprotein cholesterol (HDL-C), triglyceride, and fasting plasma glucose levels; blood pressure; and incidence of remission of central obesity. The study found that Tai Chi improved waist circumference in adults with central obesity. Ann Intern Med PubMed 34058100 10.7326/M20-7014 https://pubmed.ncbi.nlm.nih.gov/34058100/
Effects of mindfulness-based tai chi chuan on physical performance and cognitive function among cognitive frailty older adults: A six-month follow-up of a randomized controlled trial Jiayuan Z, Xiang-Zi J, Li-Na M, Jin-Wei Y, Xue Y. 2022 Randomized Controlled Trial Linking Intervention and Impact Yes The study looked at the impact of a mindfulness-based Tai Chi Chuan intervention on physical performance and cognitive function. The study aimed to understand the impact for cognitive frailty older adults. Yes No Favorable The study found improvement in cognitive function and physical performance between time groups. Rate of CF was significantly different between groups after 6 months. The MTCC intervention group had lower prevalence of frailty and better cognitive function. J Prev Alzheimers Dis PubMed 35098980 10.14283/jpad.2021.40 https://pubmed.ncbi.nlm.nih.gov/35098980/
Harnessing the benefits of yoga for myositis, muscle dystrophies, and other musculoskeletal disorders Saud A, Abbasi M, Merris H, Parth P, Jones XM, Aggarwal R, Gupta L. 2022 Systematic Review Linking Intervention and Impact Yes This review found literature on the impact of yoga therapy interventions on systemic chronic diseases Favorable The study found that yoga improved chronic pain, lung function, improved balance, and mental health. Clin Rheumatol PubMed 35854165 10.1007/s10067-022-06280-2 https://pubmed.ncbi.nlm.nih.gov/35854165/
An evidence map of the effect of tai chi on health outcomes Solloway MR, Taylor SL, Shekelle PG, Miake-Lye IM, Beroes JM, Shanman RM, Hempel S. 2016 Other Linking Intervention and Impact Yes The study looks at the volume and focus of Tai Chi research that shows health outcomes. Favorable Studies found in this reviewed showed promising results for hypertension, fall prevention outside of institutions, cognitive performance, osteoarthritis, depression, chronic obstructive pulmonary disease, pain, balance, confidence, and muscle strength. The review did find methodological limitations in the studies. Syst Rev PubMed 27460789 10.1186/s13643-016-0300-y https://pubmed.ncbi.nlm.nih.gov/27460789/
Effect of yoga on health-related outcomes in people at risk of fractures: A systematic review Kim KV, Bartley J, Ashe MC, Bardai Z, Butt DA, Chilibeck PD, Ponzano M, Rodrigues IB, Stapleton J, Thabane L, Wark JD, Giangregorio L. 2022 Systematic Review Linking Intervention and Impact Yes The s study looked at the impact of yoga for men and postmenopausal women with increased risk of fracture. Yes Yes (50+) Neutral Evidence had low certainty and yoga did now show effect on health-related quality of life and mixed results for other outcomes. Appl Physiol Nutr Metab PubMed 34914565 10.1139/apnm-2021-0736 https://pubmed.ncbi.nlm.nih.gov/34914565/
Tai chi for fall prevention and balance improvement in older adults: A systematic review and meta-analysis of randomized controlled trials Chen W, Li M, Li H, Lin Y, Feng Z. 2023 Systematic Review Linking Intervention and Impact Yes This review found literature on impact of Tai Chi on fall prevention and balance improvement in older adults Yes Yes (60+) Favorable Tai Chi reduced the risk of falls and decreased the number of falls in older adults. It also improved balance. Front Public Health PubMed 37736087 10.3389/fpubh.2023.1236050 https://pubmed.ncbi.nlm.nih.gov/37736087/
Effectiveness of tai chi on older adults: A systematic review of systematic reviews with re-meta-analysis Leung LYL, Tam HL, Ho JKM. 2022 Systematic Review Linking Intervention and Impact Yes Examined the impact of Tai Chi on the physical/psychological conditions, cognitive abilities and quality of life in older adults. Yes Yes (50+) Favorable The review found 24 eligible studies that demonstrated Tai Chi can be an effective intervention for older adults for improving physical and psychological conditions, cognitive abilities, and QoL. Arch Gerontol Geriatr PubMed 36058045 10.1016/j.archger.2022.104796 https://pubmed.ncbi.nlm.nih.gov/36058045/
Effects of tai chi combined with tdcs on cognitive function in patients with mci: A randomized controlled trial Xu Y, Zhu J, Liu H, Qiu Z, Wu M, Liu J, Wu J, Huang J, Liu Z, Liu W, Tao J. 2023 Randomized Controlled Trial Linking Intervention and Impact Yes This study looks at the impact of a Tai Chi intervention combined with transcranial direct current stimulation (tDCS) on the cognitive performance of patients with mild cognitive impairment. Yes (50 - 75) Yes (50+) Favorable The study found that there was significant improvement in global cognitive performance, memory, execution function, and attention in patients with MCI from the Tai Chi intervention combined with tDCS. Front Public Health PubMed 37608981 10.3389/fpubh.2023.1199246 https://pubmed.ncbi.nlm.nih.gov/37608981/
Systematic review of yoga interventions to promote cardiovascular health in older adults Barrows JL, Fleury J. 2016 Systematic Review Linking Intervention and Impact Yes The review looked for literature on yoga-based physical activity interventions to understand the impact on cardiovascular health in older adults. Yes Yes (sample mean age 60+) Favorable The review found there was significant improvement in blood pressure, body composition, glucose, and lipids from yoga-based interventions. West J Nurs Res PubMed 26689218 10.1177/0193945915618610 https://pubmed.ncbi.nlm.nih.gov/26689218/
Tai chi for health and well-being: A bibliometric analysis of published clinical studies between 2010 and 2020 Yang GY, Sabag A, Hao WL, Zhang LN, Jia MX, Dai N, Zhang H, Ayati Z, Cheng YJ, Zhang CH, Zhang XW, Bu FL, Wen M, Zhou X, Liu JP, Wayne PM, Ee C, Chang D, Kiat H, Hunter J, Bensoussan A. 2021 Other Linking Intervention and Impact Yes The review found literature on the impact of Tai Chi interventions. Favorable 987 studies were identified and 93.8% reported a least one favorable outcome from Tai Chi. Complement Ther Med PubMed 34118389 10.1016/j.ctim.2021.102748 https://pubmed.ncbi.nlm.nih.gov/34118389/
Tai chi improves cognitive function of dementia patients: A systematic review and meta-analysis Liu DM, Wang L, Huang LJ. 2023 Systematic Review Linking Intervention and Impact Yes The review found literature on the impact of Tai Chi on cognitive and physical function in elderly individuals with dementia. Yes Dementia Favorable The review identified 7 studies that demonstrated the Tai Chi intervention improved cognitive function among persons with dementia but had no significant impact on physical and emotional benefits. Altern There Health Med PubMed 35839111 https://pubmed.ncbi.nlm.nih.gov/35839111/
Tai chi improves psychoemotional state, cognition, and motor learning in older adults during the COVID-19 pandemic Solianik R, Mickevičienė D, Žlibinaitė L, Čekanauskaitė A. 2021 Randomized Controlled Trial Linking Intervention and Impact Yes This study looked at the impact of a 10-week Tai Chi intervention to understand the effect on psych emotional state, cognition, and motor learning in older adults. The study looked at this during the COVID-19 pandemic. Yes Yes (60-78) Favorable The study found that Tai Chi decreased perceived stress, decreased depressive symptoms and increased BDNF levels. It demonstrated Tai Chi could improve mental and physical function in older adults during pandemic conditions. Exp Gerontol PubMed 33887380 10.1016/j.exger.2021.111363 https://pubmed.ncbi.nlm.nih.gov/33887380/
Effect of tai chi on cognitive function among older adults with cognitive impairment: A systematic review and meta-analysis Gu R, Gao Y, Zhang C, Liu X, Sun Z. 2021 Systematic Review Linking Intervention and Impact Yes This review found literature on the impact of Tai Chi on cognitive impairment patients Neutral The review found 9 studies but limited evidence to show that Tai Chi is effective for older adults with cognitive impairment. Evid Based Complement Alternat Med PubMed 34394392 10.1155/2021/6679153 https://pubmed.ncbi.nlm.nih.gov/34394392/
A randomized controlled trial of tai chi chih or health education for geriatric depression Lavretsky H, Milillo MM, Kilpatrick L, Grzenda A, Wu P, Nguyen SA, Ercoli LM, Siddarth P. 2022 Randomized Controlled Trial Linking Intervention and Impact Yes This study looked at a combined Tai Chi Chih (TCC) or Health Education and Wellness training (HEW) with the stable standard antidepressant treatment intervention to understand the impact on mood and cognitive functioning in depressed older adults. Yes Yes (60+) Favorable The study found that both TCC and HEW showed improved symptoms of depression in older adults when combined with a standard antidepressant treatment. TCC improving general health more than HEW. Am J Geriatr Psychiatry PubMed 34404606 10.1016/j.jagp.2021.07.008 https://pubmed.ncbi.nlm.nih.gov/34404606/
Health impacts of unlimited access to networked transportation in older adults Saxon L, Ebert R, Sobhani M. 2019 Prospective Cohort Study Linking Intervention and Impact Grey Literature This study examines the effect of unlimited transportation access on health among older adults. Yes Yes Favorable Improved quality-of-daily-living was reported in 90% of subjects and 66% reported increased social visits. The Journal of mHealth Siren https://thejournalofmhealth.com/health-impacts-of-unlimited-access-to-networked-transportation-in-older-adults/
Going to the doctor: Rideshare as nonemergency medical transportation Fraade-Blanar L, Koo T, Whaley CM 2021 Other Linking Intervention and Impact Grey Literature Rideshare-based transportation was provided to individuals with complex conditions primarily for medical services, but the article includes ample data tables that speak to nonmedical needs. No Favorable Authors found that rideshare-based NEMT could help reduce system strain and satisfy an unmet or poorly met need for on-demand cost-effective solutions within the NEMT ecosystem. Other aspects of the piece address nonmedical transportation needs. RAND Research Reports Grey Literature 10.7249/RRA1019-1 https://www.rand.org/pubs/research_reports/RRA1019-1.html
Traveling towards disease: Transportation barriers to health care access Syed ST, Gerber BS, Sharp LK 2013 Other Linking Gap and Impact Yes N/A No Favorable A lack of reliable transportation can lead to missed or delayed care and medication use which can harm chronic disease management and lead to poorer health overall. J Community Health Google 23543372 10.1007/s10900-013-9681-1 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4265215/
Lack of reliable transportation for daily living among adults: United States, 2022 Ng AE, Adjaye-Gbewonyo D, Dahlhamer J 2024 Federal Policy or Report Linking Gap and Impact Grey Literature N/A No Favorable 5.7% of US adults lacked reliable transportation in 2022. Particularly among older adults with lower incomes and without insurance, this can lead to reduced access to health care and negative health outcomes overall. CDC Google https://www.cdc.gov/nchs/data/databriefs/db490.pdf
Transportation equity for older adults Fraade-Blanar L, Best R, Shih RA 2022 Other Linking Gap and Impact Grey Literature N/A Yes Favorable Transportation insecurity among older adults can lead to depression, isolation, early entry into care facilities, and delays in care which can be costly and dangerous. RAND Google 10.7249/PEA1615-1 https://www.rand.org/pubs/perspectives/PEA1615-1.html
A systematic review of interventions to minimize transportation barriers among people with chronic diseases Starbird LE, DiMaina C, Sun CA, Han HR 2019 Systematic Review Linking Intervention and Impact Yes This review appraises studies on the types and impact of interventions that address transportation to chronic are management. No Favorable Transportation insecurity disproportionately affects individuals with chronic diseases. As a result of transportation interventions, studies found an improvement in rates of cancer screening, chronic disease management, hospital utilization, and follow up adherence. J Community Health Google 30206755 10.1007/s10900-018-0572-3 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6450539/
Gender and transportation access among community-dwelling seniors Dupuis J, Weiss DR, Wolfson C 2007 Other Linking Gap and Impact Yes N/A Yes Favorable A high number of seniors who experience transportation insecurity are women. In addition, those who experience barriers to transportation have poorer health and lower income. Can J Aging Google 17613446 10.3138/cja.26.2.149 https://pubmed.ncbi.nlm.nih.gov/17613446/
Social determinants of health series: Transportation and the role of hospitals 2017 Other Linking Gap and Impact Grey Literature N/A No Favorable Reliable transportation is a vehicle for wellness and is essential to accessing health care services. Without reliable transportation, there can be delayed care, increased spending, and overall poorer health. American Hospital Association Google https://www.aha.org/ahahret-guides/2017-11-15-social-determinants-health-series-transportation-and-role-hospitals
What environmental factors influence resumption of valued activities post stroke: A systematic review of qualitative and quantitative findings Jellema S, van Hees S, Zajec J, van der Sande R, Nijhuis-van der Sanden MW, Steultjens EM. 2017 Systematic Review Linking Gap and Impact Yes N/A Yes Stroke Favorable The following environmental factors facilitated reengagement in personally valued activities post-stroke: personal adapted equipment; accessible environments; transport; services; education and information. Clin Rehabil PubMed 27681480 10.1177/0269215516671013 https://journals.sagepub.com/doi/10.1177/0269215516671013
Finding social need-les in a haystack: Ascertaining social needs of Medicare patients recorded in the notes of care managers Shafer PR, Davis A, Clark JA 2023 Other Linking Gap and Impact Yes N/A Yes Neutral Transportation as a barrier to care among Medicare enrollees with multiple chronic illnesses came up relatively less frequently in chronic care management encounters (0.1%). BMC Health Serv Res Siren 38087286 10.1186/s12913-023-10446-2 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10717654/
Addressing transportation insecurity among patients with cancer Graboyes EM, Chaiyachati KH, Sisto Gall J, Johnson W, Krishnan JA, McManus SS, Thompson L, Shulman LN, Yabroff KR 2022 Other Linking Gap and Impact Yes N/A No Cancer Favorable As a result of transportation insecurity, patients with cancer may forego, miss, delay, alter, and/or prematurely terminate necessary care. Limited data suggest that these alterations in care have the potential to increase the rates of cancer recurrence and mortality and exacerbate disparities in cancer incidence, severity, and outcomes. J Natl Cancer Inst. Siren 36130286 10.1093/jnci/djac134 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9745432/
Association of social needs and healthcare utilization among Medicare and Medicaid beneficiaries in the Accountable Health Communities model Holcomb J, Highfield L, Ferguson GM, Morgan RO 2022 Other Linking Gap and Impact Yes N/A Yes Yes Favorable Using data from the Greater Houston Accountable Health Communities (GH-AHC) model, transportation was identified as a health-related social need for 28% of participants. J Gen Intern Med Siren PMC9585111 10.1007/s11606-022-07403-w https://pubmed.ncbi.nlm.nih.gov/35132551/
Impact of transportation interventions on health care outcomes: A systematic review Solomon EM, Wing H, Steiner JF, Gottlieb LM 2020 Systematic Review Linking Intervention and Impact Yes This study summarizes existing research on the effectiveness of non-emergency medical transportation interventions. Neutral Results were mixed. More rigorous studies showed low patient uptake of transportation services and inconsistent impacts on health and utilization outcomes. Med Care Siren 31985588 10.1097/MLR.0000000000001292 https://pubmed.ncbi.nlm.nih.gov/31985588/
Access to transportation and health care visits for Medicaid enrollees with diabetes Thomas LV, Wedel KR, Christopher JE 2018 Other Linking Intervention and Impact Yes This study examines the association between Medicaid-provided non-emergency medical transportation and diabetes care visits. No Diabetes Favorable Use of nonemergency medical transportation is a significant predictor of diabetes care visits. Positive association between the use of transportation and number of visits. J Rural Health Siren 28370462 10.1111/jrh.12239 https://pubmed.ncbi.nlm.nih.gov/28370462/
Effect of interventions for non-emergent medical transportation: A systematic review and meta-analysis Shekelle PG, Begashaw MM, Miake-Lye IM, Booth M, Myers B, Renda A. 2022 Meta Analysis Linking Intervention and Impact Yes The study examines the association between interventions aimed at reducing barriers to non-emergency transportation and non-medical transportation and health and health care utilization. Neutral NEMT interventions lead to fewer missed appointments. NMT lead to improved QOL, but no change in satisfaction with life or depression. BMC Public Health PubMed 35449011 10.1186/s12889-022-13149-1 https://pubmed.ncbi.nlm.nih.gov/35449011/
Rideshare-based medical transportation for Medicaid patients and primary care show rates: A difference-in-difference analysis of a pilot program Chaiyachati KH, Hubbard RA, Yeager A, Mugo B, Shea JA, Rosin R, Grande D. 2018 Prospective Cohort Study Linking Intervention and Impact Yes This study evaluates the effect of rideshare-based medical transportation on the proportion of Medicaid patients attending scheduled primary care appointments. Favorable NEMT increased show rate; odds of showing at intervention site were 2.57 times more than control site. The authors also included an extensive description of transportation barriers faced by low-income patients that extends to non-medical transportation needs. J Gen Intern Med PubMed 29380214 10.1007/s11606-018-4306-0 https://pubmed.ncbi.nlm.nih.gov/29380214/
Physical activity levels and new public transit: A systematic review and meta-analysis Xiao C, Goryakin Y, Cecchini M. 2019 Meta Analysis Linking Intervention and Impact Yes Meta-analysis evaluating the association between new public transportation options and intensities of physical activity. Favorable Building new public transit options is associated with a statistically significant increase in light to moderate physical activity levels Am J Prev Med PubMed 30777164 10.1016/j.amepre.2018.10.022 https://pubmed.ncbi.nlm.nih.gov/29433955/
The association of physical activity behaviors and patterns with aging acceleration: Evidence from the UK biobank Zhu J, Yang Y, Zeng Y, Han X, Chen W, Hu Y, Qu Y, Yang H, Valdimarsdóttir UA, Fang F, Song H. 2023 Other Linking Intervention and Impact Yes This study examines the relationship between physical activity behaviors and patterns with acceleration of the aging process. Physical activity patterns include activities such as walking, light and heavy housework, and use of public transportation. Favorable Public transportation use was associated with a lower risk of aging acceleration J Gerontol A Biol Sci Med Sci PubMed 36815559 10.1093/gerona/glad064 https://pubmed.ncbi.nlm.nih.gov/36815559/
Staying connected: Alternative transportation use, neighborhoods, and social participation among older Americans Latham-Mintus K, Manierre M, Miller K. 2022 Other Linking Intervention and Impact Yes This study examines the effect of alternative transportation use on participation in diverse social activities among older adults Yes Favorable The use of public transportation, paratransit, getting a ride, or walking/using wheelchair/scooter to get places was associated with participating in more types of social activities. Respondents who used alternative transportation had less steep declines in participation. The effect of getting rides and using paratransit services was more pronounced among respondents living in disordered neighborhoods. Gerontologist PubMed 34133722 10.1093/geront/gnab084 https://pubmed.ncbi.nlm.nih.gov/34133722/
Health impacts of the Cambridgeshire Guided Busway: A natural experimental study Ogilvie D, Panter J, Guell C, Jones A, Mackett R, Griffin S. 2016 Other Linking Intervention and Impact Yes This review analyzes the effect of investment in new high-quality transport infrastructure on increase in active commuting and wider health impacts of changes in travel behavioral, and determinants of the use and uptake of active commuting. Favorable New transit affected commuting behavior. Observational evidence suggesting a relationship between active commuting, greater overall physical activity, and improved well-being and weight status. Health impacts of the Cambridgeshire Guided Busway: a natural experimental study PubMed 26764445 10.3310/phr04010 https://pubmed.ncbi.nlm.nih.gov/26764445/
Are detailed, patient-level social determinant of health factors associated with physical function and mental health at presentation among new patients with orthopedic conditions? Bernstein DN, Lans A, Karhade AV, Heng M, Poolman RW, Schwab JH, Tobert DG. 2023 Other Linking Gap and Impact Yes N/A Favorable A lack of reliable transportation was associated with worse physical and mental health symptoms at new patient encounters among patients with orthopedic conditions. Clin Orthop Relat Res PubMed 36201422 10.1097/CORR.0000000000002446 https://pubmed.ncbi.nlm.nih.gov/36201422/
Public transit generates new physical activity: Evidence from individual GPS and accelerometer data before and after light rail construction in a neighborhood of Salt Lake City, Utah, USA Miller HJ, Tribby CP, Brown BB, Smith KR, Werner CM, Wolf J, Wilson L, Oliveira MG. 2015 Other Linking Intervention and Impact Yes This study examines the effect of light rail transit on physical activity levels. Favorable Building new public transit options is associated with a statistically significant increase in light to moderate physical activity levels Health Place PubMed 26340643 10.1016/j.healthplace.2015.08.005 https://pubmed.ncbi.nlm.nih.gov/27583528/
Seasonal patterns of community participation and mobility of wheelchair users over an entire year Borisoff JF, Ripat J, Chan F. 2018 Prospective Cohort Study Linking Gap and Impact Yes N/A Favorable Among people who use wheelchairs to participate and move at home and in the community, mobility was affected by seasons and daily weather. Inaccessible public environments were the primary barrier to community mobility and participation; access to social supports and private transportation were the primary supports. Arch Phys Med Rehabil PubMed 29580935 10.1016/j.apmr.2018.02.011 https://pubmed.ncbi.nlm.nih.gov/29580935/
Municipal transportation policy as a population health intervention: Estimating the impact of the City of Ottawa transportation master plan on diabetes incidence Arnason T, Tanuseputro P, Tuna M, Manuel D. 2019 Prospective Cohort Study Linking Gap and Impact Yes N/A Favorable A population-level municipal transportation policy shift could prevent as many as 1620 incident cases of diabetes over 10 years, the largest number prevented by increases in public transit use. This population effect was equal to 17,300 inactive individuals or 12,300 inactive individuals > 45 years old undertaking a clinical preventive intervention to increase physical activity. Can J Public Health PubMed 30628043 10.17269/s41997-018-0168-9 https://pubmed.ncbi.nlm.nih.gov/30628043/
Trips4health: a single-blinded randomized controlled trial incentivizing adult public transport use for physical activity gain Evans JT, Stanesby O, Blizzard L, Jose K, Sharman MJ, Ball K, Greaves S, Palmer AJ, Cooper K, Gall SL, Cleland VJ. 2023 Randomized Controlled Trial Linking Intervention and Impact Yes This study aimed to determine the effect of a financial incentive-based intervention on public transportation use and physical activity. Favorable This study found evidence that financial incentive-based intervention to increase public transport use is effective in increasing transport-related physical activity Int J Behav Nutr Phys Act PubMed 37587424 10.1186/s12966-023-01500-7 https://pubmed.ncbi.nlm.nih.gov/37587424/
The social context of driving cessation: Understanding the effects of cessation on the life satisfaction of older drivers and their social partners Schryer E, Boerner K, Horowitz A, Reinhardt JP, Mock SE. 2019 Prospective Cohort Study Linking Gap and Impact Yes N/A Yes Neutral Driving cessation of older adults was associated with a decline in life satisfaction among social partners but not for the drivers. Life satisfaction was greater among the social partners of ex-drivers who used public transportation more frequently. J Appl Gerontol PubMed 29183239 10.1177/0733464817741683 https://pubmed.ncbi.nlm.nih.gov/29183239/
Effect of a group intervention to promote older adults' adjustment to driving cessation on community mobility: A randomized controlled trial Liddle J, Haynes M, Pachana NA, Mitchell G, McKenna K, Gustafsson L. 2014 Randomized Controlled Trial Linking Intervention and Impact Yes This study evaluates the effect of a group education and support program on community mobility. Favorable Participating in the intervention was significantly associated with a higher number of episodes away from home per week. Participation in the intervention also significantly predicted higher use of public transport at immediately postintervention, higher use of walking at immediately postintervention, increased aspects of community mobility self-efficacy, and higher satisfaction with transport at 3-month follow-up. Gerontologist PubMed 23512770 10.1093/geront/gnt019 https://pubmed.ncbi.nlm.nih.gov/23512770/
A pilot randomized trial of a companion robot for people with dementia living in the community Liang A, Piroth I, Robinson H, MacDonald B, Fisher M, Nater UM, Skoluda N, Broadbent E. 2017 Randomized Controlled Trial Linking Intervention and Impact Yes The authors test the social, behavioral, and physiological effects of a companion robot among people with dementia in a day care and home setting. Yes Dementia Favorable Observations showed that Paro significantly improved facial expressions (affect) and communication with staff (social interaction) at the day care centers. Sub analyses showed that care recipients with less cognitive impairment responded significantly better to Paro. There were no significant differences in care recipient dementia symptoms, nor physiological measures between the intervention and control group. J Am Med Dir Assoc PubMed 28668664 10.1016/j.jamda.2017.05.019 https://pubmed.ncbi.nlm.nih.gov/28668664/
Primary care-based interventions addressing social isolation and loneliness in older people: A scoping review Galvez-Hernandez P, González-de Paz L, Muntaner C 2022 Systematic Review Linking Intervention and Impact Yes This review identifies and characterizes loneliness and social isolation interventions, and detect factors influencing implementation of said interventions in primary care. Yes Neutral There is an apparent lack of consistency in strategies to identify lonely and socially isolated older adults. BMJ Open Siren 35121608 10.1136/bmjopen-2021-057729 https://pubmed.ncbi.nlm.nih.gov/35121608/
The effect of social support in chronic back pain: Number of treatment sessions and reported level of disability Oraison HM, Kennedy GA. 2021 Prospective Cohort Study Linking Intervention and Impact Yes The authors test the effect of social support on treatment uptake and adherence in chronic back pain patients. Yes Favorable Findings indicated that age, social support had a significant positive effect on the number of treatment sessions attended by participants and that life control, affective distress, and level of social support were negatively related to disability levels Disabil Rehabil PubMed 31564167 10.1080/09638288.2019.1668969 https://pubmed.ncbi.nlm.nih.gov/31564167/
A social robot intervention on depression, loneliness, and quality of life for taiwanese older adults in long-term care Chen SC, Moyle W, Jones C, Petsky H. 2020 Other Linking Intervention and Impact Yes The authors evaluate the effect of a social robot intervention on mental health outcomes and quality of life among older adults in long-term care. Yes Favorable Significant changes in decreasing depression and loneliness and improving quality of life over time were identified. Three themes emerged from the interviews: (i) humanizing Paro through referring to personal experiences and engagement; (ii) increased social interaction with other people; and (iii) companionship resulting in improved mental well-being. Int Psychogeriatr PubMed 32284080 10.1017/S1041610220000459 https://pubmed.ncbi.nlm.nih.gov/32284080/
Friends from the future: A scoping review of research into robots and computer agents to combat loneliness in older people Gasteiger N, Loveys K, Law M, Broadbent E. 2021 Other Linking Intervention and Impact Yes This review examines studies on the effectiveness of interventions using social robots or computer agents to reduce loneliness in older adults. Yes Neutral The majority of results showed that robots or computer agents positively impacted at least one loneliness outcome measure. Some unintended negative consequences on social outcomes were reported, such as sadness when the robot was removed. Overall, the interventions helped to combat loneliness by acting as a direct companion (69%), a catalyst for social interaction (41%), facilitating remote communication with others (10%) and reminding users of upcoming social engagements (3%). Clin Interv Aging PubMed 34079242 10.2147/CIA.S282709 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8163580/
Positive and negative social support and depressive symptoms according to economic status among adults in Korea: Cross-sectional results from the health examinees-gem study Lee HY, Oh J, Kawachi I, Heo J, Kim S, Lee JK, Kang D. 2019 Other Linking Gap and Impact Yes N/A Favorable The level of positive and negative social support showed a negative and positive association with depressive symptom score, a negative association between level of positive social support and depressive symptom score was more pronounced as income was lower and level of negative social support was higher BMJ Open PubMed 31005905 10.1136/bmjopen-2018-023036 https://pubmed.ncbi.nlm.nih.gov/31005905/
Effectiveness of a social inclusion program in people with non-affective psychosis Mazzi F, Baccari F, Mungai F, Ciambellini M, Brescancin L, Starace F. 2018 Other Linking Intervention and Impact Yes This study examines associations between social interventions and personal and social recovery outcomes among adults. Yes Favorable The results of the study suggest that social inclusion interventions may be effective in people suffering from non-affective psychosis. A dose-effect relationship was also found between higher number of activities per patient and better outcomes within both social and psychopathological domains. BMC Psychiatry PubMed 29879925 10.1186/s12888-018-1728-5 https://pubmed.ncbi.nlm.nih.gov/29879925/
Relationship between social engagement and diabetes incidence in a middle-aged population: Results from a longitudinal nationwide survey in Japan Shibayama T, Noguchi H, Takahashi H, Tamiya N. 2018 Other Linking Gap and Impact Yes N/A No Yes Diabetes Favorable Respondents who participated in social activities, had the companionship of friends, lived with someone and were employed were significantly less vulnerable to diabetes than were those who did not. J Diabetes Investig PubMed 32586693 10.1111/jdi.12820 https://pubmed.ncbi.nlm.nih.gov/29430865/
Peer companionship for mental health of older adults in primary care: A pragmatic, nonblinded, parallel-group, randomized controlled trial Conwell Y, Van Orden KA, Stone DM, McIntosh WL, Messing S, Rowe J, Podgorski C, Kaukeinen KA, Tu X. 2021 Randomized Controlled Trial Linking Intervention and Impact Yes The authors test the effect of peer companionship intervention on mental health outcomes among adults. Yes Yes Neutral There was no difference between groups in change in suicidal ideation or belonging; intervention had greater reduction in depression and perceived burden on others Am J Geriatr Psychiatry PubMed 26156119 10.1016/j.jagp.2020.05.021 https://pubmed.ncbi.nlm.nih.gov/32586693/
Social support buffering of the relation between low income and elevated blood pressure in at-risk African-American adults Coulon SM, Wilson DK. 2015 Other Linking Gap and Impact Yes N/A Favorable Results indicated an inverse relation between social support and diastolic BP, and also an interaction with income, such that higher social support related to lower diastolic BP in the lowest-income individuals. The hypothesized buffering effect of social support on the adverse relation of income to BP was partially supported in at-risk African-American adults. J Behav Med PubMed 32791383 10.1007/s10865-015-9656-z https://pubmed.ncbi.nlm.nih.gov/26156119/
The associations between loneliness, social exclusion and pain in the general population: A N=502,528 cross-sectional UK Biobank study Allen SF, Gilbody S, Atkin K, van der Feltz-Cornelis C. 2020 Other Linking Gap and Impact Yes N/A Yes Favorable The findings show loneliness and social exclusion as a multifaceted construct are linked to an increased prevalence of pain. J Psychiatr Res PubMed 38175944 10.1016/j.jpsychires.2020.06.028 https://pubmed.ncbi.nlm.nih.gov/32791383/
Examining the effect of contactless intergenerational befriending intervention on social isolation among older adults and students' attitude toward companionship: Content analysis Sen K, Laheji N, Ramamonjiarivelo Z, Renick C, Osborne R, Beauvais B. 2024 Other Linking Gap and Impact Yes N/A Yes Favorable Intergenerational befriending intervention reduced boredom and loneliness among older adults and enhanced positive attitude and confidence among university students. Older adults showed interest in the intervention and shared their daily life experiences with the students, which helped to reduce the gap between generations. JMIR Aging PubMed 35394621 10.2196/47908 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10865196/
Participant perspectives on the effects of an African American faith-based health promotion educational intervention: A qualitative study Majee W, Anakwe A, Onyeaka K, Laboy V, Mutamba J, Shikles M, Chen LW. 2023 Other Linking Intervention and Impact Yes The authors evaluate the effect of Live Well by Faith, a government support faith-based program to promote healthy living across several African American Churches, on promoting overall wellness among African Americans. Yes Favorable Most participants reported increased awareness about chronic health conditions, better social supports to facilitate behavior change, and creation of health networks within the community. J Racial Ethn Health Disparities PubMed 27346650 10.1007/s40615-022-01299-2 https://pubmed.ncbi.nlm.nih.gov/35394621/
Effects of a home-based and volunteer-administered physical training, nutritional, and social support program on malnutrition and frailty in older persons: A randomized controlled trial Luger E, Dorner TE, Haider S, Kapan A, Lackinger C, Schindler K. 2016 Randomized Controlled Trial Linking Intervention and Impact Yes This study evaluates the effect of a home-based and volunteer-administered physical training and nutritional intervention program compared with social support intervention nutritional and frailty status among prefrail and frail older adults living in the community. Yes Favorable The results indicate that a home-based physical training, nutritional, and social support intervention conducted by nonprofessionals is feasible and can help to tackle malnutrition and frailty in older persons living at home. Furthermore, social support alone also can result in improvement. In particular, older adults with impaired nutritional status at baseline can benefit more from the intervention. J Am Med Dir Assoc PubMed 38709573 10.1016/j.jamda.2016.04.018 https://pubmed.ncbi.nlm.nih.gov/27346650/
A mixed methods feasibility study of a virtual group-based social support program for older adults in residential care Millett G, Franco G, Fiocco AJ. 2024 Other Linking Intervention and Impact Yes This study evaluates the effect of the JAVA Music Club-Digital (JMC-D), a social intervention designed to mitigate risks of physical distancing due COVID-19 pandemic isolation, on mental health outcomes among older adults living in residential care. Yes Favorable Across the three time points there was a large effect for depressive symptoms, social isolation, and quality of life, though not statistically significant. There was a significant immediate increase in happiness following engagement in the JMC-D sessions. Aging Ment Health PubMed 29430865 10.1080/13607863.2024.2345776 https://pubmed.ncbi.nlm.nih.gov/38709573/
Effects of horticultural therapy on psychosocial health in older nursing home residents: A preliminary study Chen YM, Ji JY. 2015 Prospective Cohort Study Linking Intervention and Impact Yes The authors examine the effect of horticultural therapy on psychosocial health outcomes in older adults living in nursing homes. Yes Favorable The results of generalized estimating equation showed significant improvements in depression and loneliness. Four categories emerged from the qualitative data content analysis: social connection, anticipation and hope, sense of achievement, and companionship. J Nurs Res PubMed 25534575 10.1097/jnr.0000000000000063 https://pubmed.ncbi.nlm.nih.gov/25534575/
Intervention to reduce perceived loneliness in community-dwelling older people Rodríguez-Romero R, Herranz-Rodríguez C, Kostov B, Gené-Badia J, Sisó-Almirall A 2020 Randomized Controlled Trial Linking Intervention and Impact Yes The authors test perceived loneliness and depression and social support and quality of life among older adults living in the community, compared with non-lonely controls from the same area. Activities studied included educational workshops, mindfulness, yoga, walking and visits to urban gardens. Yes Favorable The intervention mainly reached people with moderate loneliness and significantly improved the perception of loneliness, depressive symptoms, social support and the mental health component of the quality of life. Scand J Caring Sci Siren 32285499 10.1111/scs.12852 https://pubmed.ncbi.nlm.nih.gov/32285499/
User-friendly chatbot to mitigate the psychological stress of older adults during the COVID-19 pandemic: Development and usability study Chou YH, Lin C, Lee SH, Lee YF, Cheng LC. 2024 Prospective Cohort Study Linking Intervention and Impact Yes The authors examine the effect of chatbots on psychological stress among older adults amidst social isolation during the COVID-19 pandemic. Yes Favorable Use of the chatbot lead to loneliness significantly improving in the older group ≥65 years. JMIR Form Res PubMed 38477965 10.2196/49462 https://pubmed.ncbi.nlm.nih.gov/38477965/
Social isolation and social support influence health service utilization and survival after a cardiovascular disease event: A systematic review Freak-Poli R, Hu J, Phyo AZZ, Barker SF. 2023 Systematic Review Linking Intervention and Impact Yes This review appraises studies on the association between social isolation, low social support, and loneliness with health service utilization and survival after a cardiovascular disease event among adults. Cardiovascular Disorders Favorable Lower social support is associated with high-intensity healthcare services, lower outpatient rehabilitation attendance, greater rehospitalization and poorer survival Int J Environ Res Public Health PubMed 36981761 10.3390/ijerph20064853 https://pubmed.ncbi.nlm.nih.gov/36981761/
The effect of a social robot intervention on sleep and motor activity of people living with dementia and chronic pain: A pilot randomized controlled trial Pu L, Moyle W, Jones C, Todorovic M. 2021 Randomized Controlled Trial Linking Intervention and Impact Yes The authors evaluate the effect of a social robot intervention on sleep and motor activity among nursing home residents living with dementia and chronic pain. Yes Dementia Favorable Intervention group had greater increase in night sleep period, daytime wakefulness, and greater reduction in daytime sleep. No significant results were found for motor activity. Maturitas PubMed 33358203 10.1016/j.maturitas.2020.09.003 https://pubmed.ncbi.nlm.nih.gov/33358203/
Internet-based conversational engagement randomized controlled clinical trial (I-CONNECT) among socially isolated adults 75+ years old with normal cognition or mild cognitive impairment: Topline results Dodge HH, Yu K, Wu CY, Pruitt PJ, Asgari M, Kaye JA, Hampstead BM, Struble L, Potempa K, Lichtenberg P, Croff R, Albin RL, Silbert LC; I-CONECT Team. 2024 Randomized Controlled Trial Linking Intervention and Impact Yes The authors evaluate the effect of enhanced social interactions, internet-based conversational engagement, on brain function among socially isolated older adults without dementia. Yes Dementia Favorable Experimental group had higher global cognitive test scores; experimental group participants with normal cognition had higher language-based executive function; experimental group of mild cognitive impairment subjects had higher encoding function Gerontologist PubMed 37935416 10.1093/geront/gnad147 https://pubmed.ncbi.nlm.nih.gov/37935416/
Effects of a family-based diabetes intervention on family social capital outcomes for Mexican American adults McEwen MM, Pasvogel A, Murdaugh C. 2019 Randomized Controlled Trial Linking Intervention and Impact Yes The authors evaluate the effect of a culturally-tailored family-based self-management education and social support intervention on family social capital with among Mexican American adults with type 2 diabetes and their family member. Yes Diabetes Neutral Social integration scores did not change over time, sustained intervention effect was noted for family efficacy for general health and total family efficacy Diabetes Educ PubMed 30895881 10.1177/0145721719837899 https://pubmed.ncbi.nlm.nih.gov/30895881/
The relationships between social support and loneliness: A meta-analysis and review Zhang X, Dong S. 2022 Meta Analysis Linking Gap and Impact Yes N/A Favorable Higher levels of social support were negatively correlated with loneliness, with stronger results for rural populations, effect of perceived social supports is greater than others, and friend support is stronger than family and significant other support. Acta Psychol (Amst) PubMed 35576818 10.1016/j.actpsy.2022.103616 https://pubmed.ncbi.nlm.nih.gov/35576818/
Interventions associated with reduced loneliness and social isolation in older adults: A systematic review and meta-analysis Hoang P, King JA, Moore S, Moore K, Reich K, Sidhu H, Tan CV, Whaley C, McMillan J. 2022 Meta Analysis Linking Intervention and Impact Yes This study examines interventions associated with a reduction in loneliness and social isolation among older adults. Yes Neutral Social intervention studies had no effect on loneliness and/or isolation. JAMA Netw Open PubMed 36251294 10.1001/jamanetworkopen.2022.36676 https://pubmed.ncbi.nlm.nih.gov/36251294/
Addressing social isolation to improve the health of older adults: A rapid review Veazie S, Gilbert J, Winchell K, Paynter R, Guise JM. 2019 Systematic Review Linking Intervention and Impact Grey Literature The authors reviewed recent literature evaluating the effectiveness of multiple interventions that target social isolation and loneliness to improve health care and/or health care utilization. Yes Neutral Few social interventions had positive effects on social isolation and health outcomes Agency for Healthcare Research and Quality PubMed 30830728 https://www.ncbi.nlm.nih.gov/books/NBK537909/
Do interventions reducing social vulnerability improve health in community dwelling older adults? A systematic review Mah J, Rockwood K, Stevens S, Keefe J, Andrew MK. 2022 Systematic Review Linking Intervention and Impact Yes The authors appraised evidence on the effectiveness of multiple complex interventions designed to reduce social vulnerability to improve health related outcomes among older adults living in the community. Matches CMS definition. Yes Favorable There was evidence to support positive influences of social support interventions on function, cognition, subjective health, and reduced hospital utilization. The evidence was mixed for non-hospital healthcare utilization and insufficient to determine effect on mortality. Clin Interv Aging PubMed 35431543 10.2147/CIA.S349836 https://pubmed.ncbi.nlm.nih.gov/35431543/
Leisure and social supports in relation to positive affect among older adults Lee S, Ryu J, Heo J. 2022 Other Linking Intervention and Impact Yes The authors used a bootstrapping technique to hypothesize the relationship between leisure, social support, and positive affect. Yes Favorable Results indicated that leisure activity, social support, and positive affect were significantly associated, but the relationship varied. J Appl Gerontol PubMed 33541189 10.1177/0733464821990485 https://pubmed.ncbi.nlm.nih.gov/33541189/
Customized information and communication technology for reducing social isolation and loneliness among older adults: Scoping review Thangavel G, Memedi M, Hedström K. 2022 Systematic Review Linking Intervention and Impact Yes This study explores information and communication technology solutions for reducing social isolation or loneliness among older adults. Yes Neutral Half of studies showed an improvement in health and half reported no significant changes in health. JMIR Ment Health PubMed 35254273 10.2196/34221 https://pubmed.ncbi.nlm.nih.gov/35254273/
Social interventions: an effective approach to reduce adult depression? Nagy E, Moore S. 2017 Systematic Review Linking Intervention and Impact Yes This review appraises studies on social interventions that have been designed to reduce depression in adults. Yes Favorable Majority of studies found depressive symptoms were reduced among the participating adults from the general population J Affect Disord PubMed 28472703 10.1016/j.jad.2017.04.043 https://pubmed.ncbi.nlm.nih.gov/28472703/
Effectiveness of befriending interventions: A systematic review and meta-analysis Siette J, Cassidy M, Priebe S. 2017 Systematic Review Linking Intervention and Impact Yes This review examines studies on befriending interventions, an emotional supportive relationship in which one-to-one companionship is provided on a regular basis by a volunteer, on improving physical and mental health outcomes. Yes Neutral Befriending was significantly associated with better patient-reported outcomes across primary measures, there was no significant benefit on single outcomes, including depression, quality of life, loneliness ratings, self-esteem measures, social support structures and well-being. BMJ Open PubMed 28446525 10.1136/bmjopen-2016-014304 https://pubmed.ncbi.nlm.nih.gov/28446525/
Digitally enabled peer support intervention to address loneliness and mental health: Prospective cohort analysis Bravata DM, Kim J, Russell DW, Goldman R, Pace E. 2023 Prospective Cohort Study Linking Intervention and Impact Yes This study the effects of participation with a digital peer support intervention on mental health outcomes and health-related quality of life among adults with loneliness. Yes Yes Favorable Results suggest that a digitally enabled peer support program can be effective in addressing loneliness, depression, anxiety, and health-related quality of life among a diverse population of adults with loneliness. JMIR Form Res PubMed 37930770 10.2196/48864 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10660210/
Systematic review of efficacy of interventions for social isolation of older adults Tong F, Yu C, Wang L, Chi I, Fu F. 2021 Systematic Review Linking Intervention and Impact Yes This review appraises studies on the effectiveness of existing interventions for alleviating social isolation among older adults. Yes Favorable This study suggests that group and mixed intervention targeting of older adults could be helpful for alleviating social isolation problems. The use of modern technology for remote services could also present good results. Front Psychol PubMed 34557122 10.3389/fpsyg.2021.554145 https://pubmed.ncbi.nlm.nih.gov/34557122/
The association between social support and medication adherence in patients with hypertension: A systematic review Shahin W, Kennedy GA, Stupans I. 2021 Systematic Review Linking Intervention and Impact Yes This review analyzes studies on the impact of patients' social supports on medication adherence among hypertensive patients. Cardiovascular Disorders Neutral Family members or peer support may promote better adherence in some patient groups, but inconclusive results. Pharm Pract (Granada) PubMed 34221197 10.18549/PharmPract.2021.2.2300 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8234709/
Social participation as an indicator of successful aging: An overview of concepts and their associations with health Douglas H, Georgiou A, Westbrook J. 2017 Other Linking Gap and Impact Yes N/A Yes Favorable Social connections, informal social participation and volunteering contribute to the association between social participation and health. Aust Health Rev PubMed 27712611 10.1071/AH16038 https://pubmed.ncbi.nlm.nih.gov/27712611/
Evaluation of the effectiveness of digital technology interventions to reduce loneliness in older adults: Systematic review and meta-analysis Shah SGS, Nogueras D, van Woerden HC, Kiparoglou V. 2021 Meta Analysis Linking Intervention and Impact Yes The authors evaluate the effectiveness of digital technology interventions in reducing loneliness in adults. Yes Neutral The overall effect estimates showed no statistically significant difference in the effectiveness of DTIs compared with that of usual care or non-DTIs at follow-up at 3, 4, and 6 months J Med Internet Res PubMed 34085942 10.2196/24712 https://pubmed.ncbi.nlm.nih.gov/34085942/
How do befriending interventions alleviate loneliness and social isolation among older people? A realist evaluation study Fakoya OA, McCorry NK, Donnelly M. 2021 Prospective Cohort Study Linking Intervention and Impact Yes The authors evaluate how befriending interventions work as to combat social isolation and loneliness among older adults. Yes Favorable Study improves understanding about how and why befriending interventions work. PLoS One PubMed 34499682 10.1371/journal.pone.0256900 https://pubmed.ncbi.nlm.nih.gov/34499682/
Qualitative study of the implementation and potential of a social intervention at nursing homes in Denmark Mikkelsen AS, Kristiansen M. 2021 Prospective Cohort Study Linking Intervention and Impact Yes This study examines the effectiveness of a social intervention (Tell Stories for Life) designed to strengthen social relationships between nursing home residents by telling personal stories. Yes Neutral Intervention did not appear to strengthen and establish social relations among nursing home residents. However, we found that there might be potential for strengthening residents’ sense of identity and the relation between residents and nursing home employees. Int J Environ Res Public Health PubMed 33673281 10.3390/ijerph18041808 https://pubmed.ncbi.nlm.nih.gov/33673281/
Diversity of social networks versus quality of social support: Which is more protective for health-related quality of life among older adults? Rhee TG, Marottoli RA, Monin JK. 2021 Other Linking Gap and Impact Yes N/A Yes Favorable Older adults with greater diversity of social networks, regardless of perceived quality of social support, had higher mean scores in HRQOL domains, though perceived quality of social support was not associated with HRQOL Prev Med PubMed 33516759 10.1016/j.ypmed.2021.106440 https://pubmed.ncbi.nlm.nih.gov/33516759/
Effects of the tailored activity program (TAP) on dementia-related symptoms, health events and caregiver wellbeing: A randomized controlled trial Gitlin LN, Marx K, Piersol CV, Hodgson NA, Huang J, Roth DL, Lyketsos C. 2021 Randomized Controlled Trial Linking Intervention and Impact Yes The authors evaluate the effect of the Tailored Activity Program (TAP) on clinical symptoms, health-related events, and improved caregiver wellbeing, among adults. TAP involves assessing the abilities and interests of a person living with dementia, instructing caregivers in using prescribed activities, and providing dementia education and stress reduction techniques. Yes Yes Dementia Favorable TAP conferred no benefit to agitation/aggression, but resulted in less IADL, and ADL assistance, improved caregiver wellbeing, and confidence using activities BMC Geriatr PubMed 34670502 10.1186/s12877-021-02511-4 https://pubmed.ncbi.nlm.nih.gov/34670502/
Findings from a peer-facilitated, social isolation intervention in the Veterans Health Administration healthcare system: A mixed-methods, pilot feasibility study Eliacin J, Patterson SM, Mendez DM, Burgess DJ, Traylor MH, Borden MY, Slaven JE, Matthias MS. 2023 Prospective Cohort Study Linking Intervention and Impact Yes The authors assess the feasibility of CONNECTED: a novel, telehealth-based, transdiagnostic intervention to reduce social isolation that includes individual and group components and is delivered to veterans by peers via telehealth. Yes Favorable Results also showed statistically significant improvements in social isolation, social support, anxiety, and depression. J Gen Intern Med PubMed 37723366 10.1007/s11606-023-08387-x https://pubmed.ncbi.nlm.nih.gov/37723366/
Social interventions targeting social relations among older people at nursing homes: A qualitative synthesized systematic review Mikkelsen ASB, Petersen S, Dragsted AC, Kristiansen M. 2019 Systematic Review Linking Intervention and Impact Yes This review examines studies on the effect of social interventions on social and health-related measures among nursing home residents. Yes Favorable All studies found the social interventions brought about positive trends on either/or the social and health-related measures included. Inquiry PubMed 30791836 10.1177/0046958018823929 https://pubmed.ncbi.nlm.nih.gov/30791836/
Companion animals and health in older populations: A systematic review Hughes MJ, Verreynne ML, Harpur P, Pachana NA. 2020 Systematic Review Linking Intervention and Impact Yes This review examines the effect of companion animals (including pets and more formal arrangements) on the physical and mental health of older adults. Yes Favorable Involvement with a companion animal improved participant quality of life and effectively attenuated symptoms of depression, anxiety, cognitive impairment, and the behavioral and psychiatric symptoms of dementia, increased in physical activity and improved blood pressure and heart rate variability Clin Gerontol PubMed 31423915 10.1080/07317115.2019.1650863 https://pubmed.ncbi.nlm.nih.gov/31423915/
Home modification and prevention of frailty progression in older adults: A Japanese prospective cohort study Mitoku K, and Shimanouchi S 2014 Prospective Cohort Study Linking Intervention and Impact Yes Various home modifications, most commonly the installation of handrails in the home, were implemented. Yes Favorable Mortality among older adults with home modifications was lower than among those with no modifications. Journal of Gerontological Nursing Google Scholar 10.3928/00989134-20140311-02 https://journals.healio.com/doi/full/10.3928/00989134-20140311-02
Home and environmental hazards modification for fall prevention among the elderly Campani D, Caristia S, Amariglio A, Piscone S, Ferrara LI, Barisone M, Bortoluzzi S, Faggiano F, Dal Molin A 2020 Other Linking Intervention and Impact Yes Various combinations of home modifications were implemented to reduce falls in the home, including modifications to flooring, lighting, furniture, and layouts. Yes Favorable Home modifications can help reduce the number of falls among community-dwelling older adults. To be most successful, interventions should be individualized to the older adult's particular needs. Public Health Nurs Google 33340382 10.1111/phn.12852 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8246567/
Housing accessibility for senior citizens in Sweden: Estimation of the effects of targeted elimination of environmental barriers Pettersson C, Slaug B, Granbom M, Kylberg M, Iwarsson S. 2018 Other Linking Intervention and Impact Yes Environmental barrier removal in Sweden housing stock was implemented. Yes Favorable Removing environmental barriers in the home would have the greatest effects on aging adults with complex functional needs, but would also mitigate accessibility problems faced by all community-dwelling aging adults. Scand J Occup Ther PubMed 28114837 10.1080/11038128.2017.1280078 https://www.tandfonline.com/doi/full/10.1080/11038128.2017.1280078#2543de1e-a4b2-4753-a5c7-60ad3348142b-b6de7b7c-de82-45a5-9538-313dd15c6659
A feasibility study of a home-based lifestyle-integrated physical exercise training and home modification for community-living older people (Part 2): The FIT-at-Home fall prevention program Müller C, Lautenschläger S, Dörge C, Voigt-Radloff S. 2021 Other Linking Intervention and Impact Yes FIT-at-Home, a physical exercise training and home modification intervention led by occupational therapists, was implemented. Yes Favorable The intervention was found to be feasible and appeared to have positive effects on aging, community-dwelling adults with poor health, functional limitations, and limited mobility. Disabil Rehabil PubMed 31868030 10.1080/09638288.2019.1700564 https://www.tandfonline.com/doi/full/10.1080/09638288.2019.1700564#2543de1e-a4b2-4753-a5c7-60ad3348142b-b6de7b7c-de82-45a5-9538-313dd15c6659
Capable program improves disability in multiple randomized trials Szanton SL, Leff B, Li Q, Breysse J, Spoelstra S, Kell J, Purvis J, Xue Q, Wilson J, Gitlin L 2021 Other Linking Intervention and Impact Yes CAPABLE intervention: 10 home-based sessions with occupational therapist, nurse, and handy worker engagement to enhance independence and home environment Yes Favorable All studies included in the review showed improvement in activities of daily living among older adults. Journal of the American Geriatrics Society Google 10.1111/jgs.17383 https://agsjournals.onlinelibrary.wiley.com/doi/full/10.1111/jgs.17383
Preventing falls at home: Room by room 2022 Other Linking intervention and Impact Grey Literature Numerous interventions are described to help prevent falls in the home. Yes Favorable Changes made to the home like the ones describes can prevent falls and improve home safety. National Institute on Aging Google https://www.nia.nih.gov/health/falls-and-falls-prevention/preventing-falls-home-room-room
Environmental barriers and housing accessibility problems for people with Parkinson's disease: A three-year perspective Andersson N, Slaug B, Nilsson MH, Iwarsson S. 2023 Prospective Cohort Study Linking Gap and Impact Yes N/A Favorable Numerous difficulties relating to the home environment exist, particularly relating to grab bars, stairs, and challenges reaching trash containers Scand J Occup Ther PubMed 10.1080/11038128.2021.2007998 https://www.tandfonline.com/doi/full/10.1080/11038128.2021.2007998#2b85d6ca-6520-4a3d-8e4a-aa9f2ee3f33d-b6de7b7c-de82-45a5-9538-313dd15c6659
Understanding home modification outcomes from the perspective of older people and people with a disability: Informing home modification evaluation Ainsworth E, Aplin T, de Jonge D, Bennett S. 2023 Other Linking Intervention and Impact Yes Various home modifications were implemented. Yes Yes Favorable The outcomes after a home modification that mattered to the participants were the improvement of emotional and physical health and safety, the independence and empowerment to stay at home, and the ability to plan for the future. Disabil Rehabil Google 36394257 10.1080/09638288.2022.2146765 https://pubmed.ncbi.nlm.nih.gov/36394257/
Delivering home modifications that meet older adults’ needs 2024 Other Linking Intervention and Impact Grey Literature The Home Modification Service Delivery Model, a transdisciplinary home modification intervention that engages occupational therapists, physical therapists, nonprofits, architects, contractors, care managers, primary care providers, and handypersons. Yes Favorable Home modifications can help prevent falls, enhance the aging in place experience, and support needs after a hospital stay. National Council on Aging Google https://www.ncoa.org/article/delivering-home-modifications-that-meet-older-adults-needs
Is home adjustment beneficial for the elderly? A systematic review of the literature Stillmunkés A, Goubin L, Bismuth S, Nourhashémi F, Oustric S 2015 Systematic Review Linking Intervention and Impact Yes Home adjustments implemented for older adults was the intervention. Yes Favorable The most successful interventions involved an occupational therapist. Home modifications helped preserve the autonomy of patients and preventing falls. Janvier Google Scholar 10.1684/med.2015.1180 https://www.jle.com/en/revues/med/e-docs/l_amenagement_du_domicile_des_personnes_agees_est_il_benefique_une_revue_systematique_de_la_litterature_303747/article.phtml
Housing design and community care: How home modifications reduce care needs of older people and people with disability Carnemolla P, Bridge C 2019 Other Linking Intervention and Impact Yes Participants received various home modifications depending on need, such as ramps, grab rails, handrails. Yes Favorable Home modifications were found to reduce the hours of care provided, showing that this intervention can reduce care needs. International Journal of Environmental Research and Public Health NIH National Library of Medicine 31159396 10.3390/ijerph16111951 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6604004/
Smart home-based home modification program for persons with disabilities: A pilot study Moon K, Lee Y, Kim D, Kim J 2020 Other Linking Intervention and Impact Yes A smart home-based home modification program using bluetooth or wifi and zigbee networks was the intervention. Favorable High quality of life and improved occupational performance and satisfaction were the results of the intervention. Participative Urban Health and Healthy Aging in the Age of AI (ICOST 2022) Google Scholar 10.1007/978-3-031-09593-1_22 https://link.springer.com/chapter/10.1007/978-3-031-09593-1_22
A home repair and modification program embedded within Mount Sinai visiting doctors Schiller G, Seligman A, Lubetsky S, DeCherrie LV, Reckrey J, Kopke V, Bacher N, Bhatia S, Ornstein KA. 2023 Other Linking Intervention and Impact Yes Home modification and repair pilot program after needs assessment by social worker was the intervention. Favorable Average spending per patient was $528 as part of this program. Mount Sinai staff reported the program was feasible and decreased burnout. J Appl Gerontol PubMed 36661352 10.1177/07334648221142599 https://pubmed.ncbi.nlm.nih.gov/36661352/
Home modifications for older adults: A systematic review Sheth S, Cogle CR. 2023 Systematic Review Linking Intervention and Impact Yes Various methods of home modifications for older adults was the intervention. Yes Favorable Occupational therapist involvement in modifications supplemented with clinical, physical activity, and/or behavioral components showed the most success. J Appl Gerontol PubMed 36655622 10.1177/07334648231151669 https://pubmed.ncbi.nlm.nih.gov/36655622/
Home hazard modification programs for reducing falls in older adults: A systematic review and meta-analysis Lektip C, Chaovalit S, Wattanapisit A, Lapmanee S, Nawarat J, Yaemrattanakul W. 2023 Systematic Review Linking Intervention and Impact Yes Interventions were analyzed using home modifications specifically to prevent falls in older adults. Yes Favorable Falls can be reduced by thorough and focused home modifications with follow-up. PeerJ PubMed 37489124 10.7717/peerj.15699 https://peerj.com/articles/15699/
Effect of social determinants of health interventions on adults living with disabilities: A scoping review Angelelli J, McCartney D, Roehmer C, Swart ECS, Quinby E, Darwin J, Dicianno BE. 2022 Systematic Review Linking Intervention and Impact Yes Home modifications, along with other SDoH interventions, were analyzed. Neutral Most interventions scored low using GRADE criteria and limited evidence exists comparing the interventions to outcomes. Arch Phys Med Rehabil PubMed 34756446 10.1016/j.apmr.2021.06.021 https://pubmed.ncbi.nlm.nih.gov/34756446/
Older adults' self-reported barriers to aging in place Brim B, Fromhold S, Blaney S. 2021 Systematic Review Linking Gap and Impact Yes N/A Yes Neutral Using self-reported home safety assessments, researchers found that older adults experience barriers related to home mobility and safety, home improvement and maintenance needs, and general safety and bathroom safety. J Appl Gerontol PubMed 33522379 10.1177/0733464820988800 https://pubmed.ncbi.nlm.nih.gov/33522379/
Effects of a consumer driven home modification intervention on community participation for people with mobility disabilities Greiman L, Ravesloot C, S Goddard K, Ward B. 2022 Randomized Controlled Trial Linking Intervention and Impact Yes Home usability changes through the Home Usability Program was the intervention. Mobility Disability Favorable The program increased participation in the community for people with mobility disabilities. Disabil Health J PubMed 34521604 10.1016/j.dhjo.2021.101210 https://pubmed.ncbi.nlm.nih.gov/34521604/
Home modifications and disability outcomes: A longitudinal study of older adults living in England Chandola T, Rouxel P. 2022 Prospective Cohort Study Linking Intervention and Impact Yes Internal and external housing modifications were implemented, including widened doorways, ramps, automatic doors, parking and lifts; and rails, bathroom/kitchen modifications, and chair lifts. Yes Favorable External housing modifications reduced falls, pain, poor health, and the probability of no social activities and moving homes. Internal modifications had similar but less consistent effects. Lancet Reg Health Eur PubMed 35814336 10.1016/j.lanepe.2022.100397 https://pubmed.ncbi.nlm.nih.gov/35814336/
Motor control and ergonomic intervention home-based program: A pilot trial performed in the framework of the Motor Control Home Ergonomics Elderlies' Prevention of Falls (McheELP) Project Stasi S, Tsekoura M, Gliatis J, Sakellari V. 2021 Randomized Controlled Trial Linking Intervention and Impact Yes "Motor Control Home Ergonomics Elderlies' Prevention of Falls" (McHeELP) - an exercise and home arrangement program - was implemented. Yes Neutral Outcome measures such as physical tests and fall screening tools showed significant improvement. No difference was recorded in mobility, self-care, usual activities, or pain or discomfort scales. Cureus PubMed 33968539 10.7759/cureus.14336 https://pubmed.ncbi.nlm.nih.gov/33968539/
Examining the effects of home modifications on perceptions of exertion and safety among people with mobility disabilities Goddard KS, Hall JP, Greiman L, Koon LM, Gray RC. 2024 Other Linking Intervention and Impact Yes The Home Usability Program (HUP) was implemented to improve accessibility, safety, and independence in community dwelling people with mobility disabilities. Mobility Disability Favorable The intervention resulted in increased safety and decreased exertion, leading to more time for other activities, including those outside the home, and enhanced socialization and independence. Disabil Health J PubMed 38369385 10.1016/j.dhjo.2024.101590 https://pubmed.ncbi.nlm.nih.gov/38369385/
Home modification to reduce falls at a health district level: Modeling health gain, health inequalities and health costs Wilson N, Kvizhinadze G, Pega F, Nair N, Blakely T. 2017 Other Linking Intervention and Impact Yes Home Safety Assessment and Modification program, which strives to reduce falls in older people, was implemented. Yes Favorable The program was found to be cost effective and to produce meaningful health gain. PLoS One PubMed 28910342 10.1371/journal.pone.0184538 https://pubmed.ncbi.nlm.nih.gov/28910342/
The potential to reduce falls and avert costs by clinically managing fall risk Stevens JA, Lee R. 2018 Other Linking Intervention and Impact Yes Various evidence-based fall interventions for older adults were implemented, including home modifications led by an occupational therapist. Yes Favorable Interventions with home modifications were found to have the greatest potential for impact. Am J Prev Med PubMed 30122212 10.1016/j.amepre.2018.04.035 https://pubmed.ncbi.nlm.nih.gov/30122212/
One-year changes in activities of daily living, usability, falls and concerns about falling, and self-rated health for different housing adaptation client profiles Malmgren Fänge A, Chiatti C, Axmon A. 2021 Prospective Cohort Study Linking Intervention and Impact Yes Five housing adaptations profileswere used, based on level of disability and age. Neutral No consistent trends were found across all profiles. Int J Environ Res Public Health PubMed 34574626 10.3390/ijerph18189704 https://pubmed.ncbi.nlm.nih.gov/34574626/
Home modifications to reduce injuries from falls in the home injury prevention intervention (HIPI) study: A cluster-randomized controlled trial Keall MD, Pierse N, Howden-Chapman P, Cunningham C, Cunningham M, Guria J, Baker MG. 2015 Randomized Controlled Trial Linking Intervention and Impact Yes Home modifications, such as handrails, grab rails, outside lighting, edging on steps, and slip-resistant surfacing, were implemented. Favorable Reduction in the rates of falls and injuries caused by falls at home were found in intervention group. Lancet PubMed 25255696 10.1016/S0140-6736(14)61006-0 https://pubmed.ncbi.nlm.nih.gov/25255696/
Effect of home modification interventions on the participation of community-dwelling adults with health conditions: A systematic review Stark S, Keglovits M, Arbesman M, Lieberman D 2017 Systematic Review Linking Intervention and Impact Yes Home modifications for adults and older adults living independently was the intervention. Favorable Home modifications were found to improve the function of people with a variety of health conditions, reduce falls among older adults, and improve caregiving for people with dementia. Am J Occup Ther PubMed 28218595 10.5014/ajot.2017.018887 https://pubmed.ncbi.nlm.nih.gov/28218595/
Home improvement and system-based health promotion for sustainable prevention of chagas disease: A qualitative study Nieto-Sanchez C, Bates BR, Guerrero D, Jimenez S, Baus EG, Peeters Grietens K, Grijalva MJ 2019 Prospective Cohort Study Linking Intervention and Impact Yes Healthy Homes for Healthy Living, a home improvement and health promotion intervention, was implemented. No Favorable The intervention addressed risk factors for Chagas disease and improved emotional, economic, and social wellbeing PLoS Negl Trop Dis PubMed 10.1371/journal.pntd.0007472 https://journals.plos.org/plosntds/article?id=10.1371%2Fjournal.pntd.0007472
Effects of occupation-based home modification and intervention using assistive devices on activities of daily living performance and risk factors at home in community-dwelling people with disabilities Jo Y, Kim H 2018 Prospective Cohort Study Linking Intervention and Impact Yes Home modification and intervention using assistive devices was the intervention. Favorable Independence was improved, and the difficulty of activities of daily living at home were decreased. Overall risk factors in the home significantly decreased, particularly in the bedroom and bathroom. Korean Journal of Occupational Therapy Google Scholar 10.14519/jksot.2018.26.3.07 https://koreascience.kr/article/JAKO201833850296650.page
Bathroom modifications among community-dwelling older adults who experience falls in the United States: A cross-sectional study Ng BP, Lu J, Tiu GF, Thiamwong L, Zhong Y 2021 Other Linking Intervention and Impact Yes Existing bathroom modifications among older community-dwelling adults who experienced a fall in the past year were observed. Yes Favorable A slight majority of the older adults had bathroom modifications and half had more than one fall. About 40% of adults with more than one fall did not have bathroom modifications. Health and Social Care Google Scholar 10.1111/hsc.13398 https://onlinelibrary.wiley.com/doi/abs/10.1111/hsc.13398
Effects of client-centered home modification and caregiver education on activity performance and satisfaction of persons with mild dementia: A case study Lee CD, Jung MY, Kim JN 2016 Case Study Linking Intervention and Impact Yes Client-centered home modification and caregiver education was the intervention. Yes Dementia Favorable Performance of activities increased after intervention. Increase in independence, difficulty, and safety was maintained after 6 months. The Journal of Korean Society of Occupational Therapy Google Scholar 10.14519/jksot.2016.24.1.07 https://scholarworks.indianapolis.iu.edu/items/f4ef85d3-2ad3-4818-bad3-7fe0e6722f0e
Survey of pest infestation, asthma, and allergy in low-income housing Wang C, Abou El-Nour MM, & Bennett GW 2007 Other Linking Gap and Impact Yes N/A Favorable Pest infestation, pesticide use, and pest allergens have health implications for residents, particularly residents with asthma. Journal of Community Health Google Scholar 10.1007/s10900-007-9064-6 https://link.springer.com/article/10.1007/s10900-007-9064-6#citeas
A method for reducing environmental pollution by using essential oils in rodent pest management program Jokić G, Blažić T, Đurović-Pejčev R, Đorđević T, Đedović S, Vukša M. 2017 Prospective Cohort Study Linking Intervention and Impact Yes Bergamot, lavender, and thyme essential oils were used as bait components to deter pests. Neutral Lavender and thyme oils had no effects on house mice diet. Bergamot oil showed a repellent effect. Environ Sci Pollut Res Int PubMed 28634803 10.1007/s11356-017-9533-0 https://pubmed.ncbi.nlm.nih.gov/28634803/
The additional benefit of residual spraying and insecticide-treated curtains for dengue control over current best practice in Cuba: Evaluation of disease incidence in a cluster randomized trial in a low burden setting with intensive routine control Toledo ME, Vanlerberghe V, Rosales JP, Mirabal M, Cabrera P, Fonseca V, Gómez Padrón T, Pérez Menzies M, Montada D, Van der Stuyft P. 2017 Randomized Controlled Trial Linking Intervention and Impact Yes Two types of insecticide interventions are included in this study: periodical intra- and peri-domiciliary residual insecticide treatment and long lasting insecticide treated curtains. Neutral In the first month, there was a significant decline in Aedes indices after residual insecticide treatment, but the effect did not last and overall dengue incidence was not reduced. PLoS Negl Trop Dis PubMed 29117180 10.1371/journal.pntd.0006031 https://pubmed.ncbi.nlm.nih.gov/29117180/
Sustainable pest management for health and well-being Liu Q 2020 Other Linking Intervention and Impact Yes Sustainable Pest Management, a systematic and sustainable approach to pest management, was implemented. Favorable The intervention promotes reduction of disease, hunger, poverty, and protects the environment. China CDC Wkly Google 10.46234/ccdcw2020.112 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8428439/
Public health issues caused by pests Environmental Protection Agency 2021 Federal Policy or Report Linking Gap and Impact Grey Literature N/A Favorable Pests can contribute to public health issues such as vector-borne diseases, asthma and allergies, and microbial diseases and infections EPA Google https://19january2021snapshot.epa.gov/pesticides/public-health-issues-caused-pests_.html
What is integrated pest management? Centers for Disease Control and Prevention 2024 Federal Policy or Report Linking Intervention and Impact Grey Literature Integrated Pest Management: an approach focusing on pest prevention, reduction, and eliminating the conditions that cause pest intervention Favorable IPM reduces the incidence of pest infestations, reducing the need to use harmful pest-control products. CDC Google https://www.cdc.gov/environmental-health-services/php/vector-control-resources/what-is-ipm.html
The social impacts of bedbug infestation as an emerging public health issue: A case report Alizadeh I, Gorouhi MA, Aghaei Afshar A, Iranpour A 2019 Case Study Linking Gap and Impact Yes N/A Neutral While bed bugs do not spread disease, infestations can produce numerous issues, such as social health problems, for the infested. Electronic Physician Google Scholar 10.19082/7636 https://pdfs.semanticscholar.org/fd00/c76e8df4121870773240f3f513ae73279e48.pdf
Investigating the association of bed bugs with infectious diseases: A retrospective case control study Sheele JM, Libertin CR, Pritt BS, Wysokinska EW, Pietri JE 2021 Other Linking Gap and Impact Yes N/A Favorable Bed bug infestation are more likely for patients with positive blood cultures, blood cultures growing coagulase-negative Staphylococcus, and those diagnosed with pneumonia, with cellulitis, or who had an infectious disease consult, a chest radiograph, and higher percentages of eosinophils in the blood. Heliyon Google Scholar 10.1016/j.heliyon.2021.e08107 https://www.cell.com/heliyon/pdf/S2405-8440(21)02210-6.pdf
Health hazards associated with arthropod infestation of stored products Hubert J, Stejskal V, Athanassiou CG, Throne JE. 2018 Other Linking Gap and Impact Yes N/A Favorable Anthropod infestation can lead to food contamination and the development of fungi and microorganisms that can produce toxins that endanger human health. Annu Rev Entomol PubMed 29324037 10.1146/annurev-ento-020117-043218 https://pubmed.ncbi.nlm.nih.gov/29324037/
Bed bugs and infectious diseases Doggett S 2018 Other Linking Gap and Impact Grey Literature N/A Favorable Bed bugs may carry infectious disease and have the ability to transmit diseases to humans. Google Scholar 10.1002/9781119171539.ch12 https://onlinelibrary.wiley.com/doi/abs/10.1002/9781119171539.ch12
Good night, sleep tight, don’t let the Cimex bite Lawangeen Z, Stein A, Haltigan E, Radhakrishnan N 2021 Case Study Linking Gap and Impact Yes N/A Favorable The authors present evidence that bed bugs can, under the right circumstances, infest organic matter, such as human skin. Journal of the American Academy of Dermatology Google Scholar 10.1016/j.jaad.2021.06.690 https://www.jaad.org/article/S0190-9622(21)01794-1/abstract
A review on bed bugs: Epidemiology, health effects, and surveillance activities Chen H, Copes R 2010 Systematic Review Linking Gap and Impact Grey Literature N/A Favorable Beg bugs can cause numerous health effects, including HBV, skin reactions, asthmatic reaction, and anemia. Ontario's Public Health Agency Google Scholar https://www.publichealthontario.ca/-/media/documents/B/2010/bed-bug-review.pdf
The mental health impact of bed bug infestations: A scoping review Ashcroft R, Seko Y, Chan LF, Dere J, Kim J, McKenzie K 2015 Systematic Review Linking Gap and Impact Yes N/A Favorable Bed bug infestations can have adverse impacts on mental health, including severe psychiatric symptoms. Int J Public Health Google Scholar 10.1007/s00038-015-0713-8 https://pubmed.ncbi.nlm.nih.gov/26298442/
Bed bugs: A public health issue Environmental Protection Agency 2024 Other Linking Gap and Impact Grey Literature N/A Favorable Bed bugs can cause allergic reactions, infections of the skin, mental health impacts on people living in infested homes. EPA Google Scholar https://www.epa.gov/bedbugs/bed-bugs-public-health-issue
Health impacts of bedbug infestation: A case of five towns in Amhara Region, Ethiopia Mekonnen D, Zenebe Y, Derbie A, Adem Y, Hailu D, Mulu W, Bereded F, Mekonnen Z, Yizengaw E, Tulu B, Biadglegne F, Mihret A, Sack U 2023 Other Linking Gap and Impact Yes N/A Favorable Among the residents with bed bug infestations, social, psychological, and health impacts were recorded. Ethiop. J. Health Dev Google Scholar https://www.researchgate.net/publication/369382113_Health_impacts_of_bedbug_infestation_A_case_of_five_towns_in_Amhara_Region_Ethiopia
Mental health effects from urban bed bug infestation (Cimex lectularius L.): A cross-sectional study Susser SR, Perron S, Fournier M, Jacques L, Denis G, Tessier F, Roberge P 2012 Other Linking Gap and Impact Yes N/A Favorable Bed bug infestation was strongly associated with anxiety symptoms and sleep disturbances. BMJ Open Google Scholar https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3467661/
Housing quality and mental health: The association between pest infestation and depressive symptoms among public housing residents Shah SN, Fossa A, Steiner AS, Kane J, Levy JI, Adamkiewicz G, Bennett-Fripp WM, Reid M 2018 Other Linking Gap and Impact Yes N/A Favorable Cockroach infested residents had almost three times the odds of experiencing high depressive symptoms than those without infestation. Dual infested homes of cockroach and mice had over five times the odds of experiencing high depressive symptoms J Urban Health Google 30141116 10.1007/s11524-018-0298-7 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6181819/
Cockroaches National Center for Healthy Housing N/A Other Linking Gap and Impact Grey Literature N/A Favorable Cockroaches can carry disease-causing germs and their debris (old shells, saliva, body parts, and droppings) can triggers asthma attacks National Center for Healthy Housing Google https://nchh.org/information-and-evidence/learn-about-healthy-housing/health-hazards-prevention-and-solutions/cockroaches/
The role of pest control in effective asthma management: A business case Brett M, Stillman L 2009 Other Linking Intervention and Impact Grey Literature Integrated Pest Management: a preventive pest control intervention that aims to reduce the need for pesticides and reduce allergen levels in the home. Favorable IPM is a cost-effective pest control intervention for high-risk asthma patients when compared to standard clinical methods of asthma treatment Asthma Regional Council of New England, Boston Public Health Commission Google Scholar https://www.asthmacommunitynetwork.org/system/files/ResourseUploads/ARC%20-%20IPM%20in%20Effective%20Asthma%20Mgmt%20-%20A%20Business%20Case.pdf
Self-reported prevalence of pests in Dutch households and the use of the health belief model to explore householders’ intentions to engage in pest control Lipman SA, Burt SA 2017 Other Linking Intervention and Impact Yes The authors measure how different rationale for pest control influenced intention to take action against pests. Favorable Interventions to encourage pest control actions should emphasize the potential health consequences of pests and reduce barriers. PLoS One Google Scholar 10.1371/journal.pone.0190399 https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0190399
Pest control statistics 2024 Bazen A, Parkman K 2024 Other Linking Gap and Impact Grey Literature N/A Favorable Pests can have many negative effects on both the mental and physical health of residents in infested homes, such as causing anxiety, transmitting diseases such as West Nile virus, Eastern Equine Encephalitis, and Zika, and more. Consumer Affairs Google Scholar https://www.consumeraffairs.com/homeowners/pest-control-statistics.html
The association between exposure to residential indoor volatile organic compounds and measures of central arterial stiffness in healthy middle-aged men and women Gilbey SE, Reid CM, Huxley RR, Soares MJ, Zhao Y, Rumchev KB. 2021 Other Linking Gap and Impact Yes N/A Favorable The study found that residential indoor VOCs exposure was adversely associated with some measures of central arterial stiffness. International Journal of Environmental Research and Public Health PubMed 35055806 10.3390/ijerph19020981 https://www.mdpi.com/1660-4601/19/2/981
A review of strategies and their effectiveness in reducing indoor airborne transmission and improving indoor air quality Nair AN, Anand P, George A, Mondal N. 2021 Systematic Review Linking Intervention and Impact Yes Numerous interventions to improve indoor air quality are evaluated in this review. Favorable The study found that environmental quality parameters such as humidity and temperature have shown considerable influence in reducing virus transmission in indoor spaces. Environmental Research PubMed 35714688 10.1016/j.envres.2022.113579 https://pubmed.ncbi.nlm.nih.gov/35714688/
Effect of portable air purifier on indoor air quality: Reduced exposure to particulate matter and health risk assessment Fazlzadeh M, Hassanvand MS, Nabizadeh R, Shamsipour M, Salarifar M, Naddafi K. 2022 Other Linking Intervention and Impact Yes Study examining the effect of air purifiers on the removal of pollutants in indoor air in a medical setting. Favorable The study found that using household air purifiers in rooms with smokers and non-smokers significantly reduces the non-carcinogenic risks of exposure to PM10 and PM2.5. Environmental Monitoring and Assessment PubMed 35925421 10.1007/s10661-022-10255-w https://pubmed.ncbi.nlm.nih.gov/35925421/
Effect of indoor air quality on the association of long-term exposure to low-level air pollutants with cognition in older adults Chen YC, Hsieh PI, Chen JK, Kuo E, Yu HL, Chiou JM, Chen JH. 2023 Prospective Cohort Study Linking Intervention and Impact Yes The authors observed the variation in exposure to PM2.5, PM10, NO2, SO2, CO, and O3 between 2011-2019. Yes Favorable The study found that tightening air quality standards may help prevent dementia. Environmental Research PubMed 36791838 10.1016/j.envres.2023.115483 https://pubmed.ncbi.nlm.nih.gov/36791838/
Oxidative stress effects of multiple pollutants in an indoor environment on human bronchial epithelial cells Cheng Y, Kong D, Ci M, Guan Y, Luo C, Zhang X, Gao F, Li M, Deng G. 2023 Other Linking Gap and Impact Yes N/A Favorable The study asserts that air pollution is one of the exogenous sources of reactive oxygen and nitrogen species. Ambient airborne particulate matter (PM) irritates the inner airways and triggers immunological responses, which are all related to the physiopathology of chronic respiratory diseases such as cancer. International Journal of Molecular Science PubMed 36614301 10.3390/ijms24010853 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9821141/#:~:text=Oxidative%20stress%20activates%20the%20lungs%E2%80%99%20epithelial%20cells%2C%20generating,of%20them%20are%20implicated%20in%20numerous%20respiratory%20diseases.
The benefits of nursing home air purification on COVID-19 outcomes: A natural experiment Jutkowitz E, Shewmaker P, Reddy A, Braun JM, Baier RR. 2023 Other Linking Intervention and Impact Yes Ultraviolet air purification systems were installed in a nursing home. Favorable The study found that intervening on air quality may have a wide impact without placing significant burden on individuals to modify their behavior. JAMA PubMed 37385591 10.1016/j.jamda.2023.05.026 https://pubmed.ncbi.nlm.nih.gov/37385591/
Effects of long-term indoor air purification intervention on cardiovascular health in elderly: A parallel, double-blinded randomized controlled trial in Hong Kong Xia X, Chan KH, Kwok T, Wu S, Man CL, Ho KF. 2024 Randomized Controlled Trial Linking Intervention and Impact Yes This study compared true-air purification to sham-air purification in indoor air purifiers. Favorable The study found evidence of cardiovascular benefits of long-term indoor air purifiers (IAPs) use, particularly on diastolic blood pressure. Environmental Research PubMed 38253196 10.1016/j.envres.2024.118284 https://pubmed.ncbi.nlm.nih.gov/38253196/
An indoor air filtration study in homes of elderly: Cardiovascular and respiratory effects of exposure to particulate matter Dorina Gabriela Karottki, Michal Spilak, Marie Frederiksen, Lars Gunnarsen, Elvira Vaclavik Brauner, Barbara Kolarik, Zorana Jovanovic Andersen, Torben Sigsgaard, Lars Barregard, Bo Strandberg, Gerd Sallsten, Peter Møller & Steffen Loft 2013 Randomized Controlled Trial Linking Intervention and Impact Yes High-efficiency particle air filter was used in older adults' living rooms and bedrooms. Yes Favorable The particle filters reduced the median concentration of PM2.5 BMC Environmental Health PubMed 24373585 https://doi.org/10.1186/1476-069X-12-116 https://link.springer.com/article/10.1186/1476-069X-12-116#article-info
Estimated effect of ventilation and filtration on chronic health risks in U.S. offices, schools, and retail stores Chan WR, Parthasarathy S, Fisk WJ, McKone TE. 2016 Other Linking Intervention and Impact Yes Changes in exposure to VOCs and PM2.5 were predicted if ventilation rate were to increase or decrease by a factor of two, and if higher efficiency air filters were used. Neutral The study suggests that increasing ventilation alone is ineffective at reducing chronic health burdens. The use of particle filtration, should also be considered. Indoor Air PubMed https://pubmed.ncbi.nlm.nih.gov/25639183/
Towards explaining the health impacts of residential energy efficiency interventions - a realist review. Part 1: Pathways Willand N, Ridley I, Maller C. 2015 Systematic Review Linking Intervention and Impact Yes Residential energy efficiency interventions (REEIs) were reviewed in this study. Favorable The review revealed that REEIs improved winter warmth and lowered relative humidity with benefits for cardiovascular and respiratory health. Social Science & Medicine PubMed  25687402 10.1016/j.socscimed.2015.02.005 https://pubmed.ncbi.nlm.nih.gov/25687402/
Health effects of home energy efficiency interventions in england: A modelling study Hamilton I, Milner J, Chalabi Z, Das P, Jones B, Shrubsole C, Davies M, Wilkinson P. 2015 Other Linking Intervention and Impact Yes The experiment modeled three scenarios measuring pollution levels using varying levels of fabric and ventilation retrofits installed within building. Favorable The study found that if properly used with ventilation, energy efficiency retrofits in housing can improve health by reducing exposure to cold and air pollutants. BMJ Open PubMed 25916488 10.1136/bmjopen-2014-007298 https://pubmed.ncbi.nlm.nih.gov/25916488/
Reducing particulates in indoor air can improve the circulation and cardiorespiratory health of old people: A randomized, double-blind crossover trial of air filtration Guo M, Du C, Li B, Yao R, Tang Y, Jiang Y, Liu H, Su H, Zhou Y, Wang L, Yang X, Zhou M, Yu W. 2021 Randomized Controlled Trial Linking Intervention and Impact Yes Randomized controlled trial in which long-term care patient rooms received a high-efficiency particulate air filter air purifier and a placebo air purifier for two days. Favorable The study found that air filtration was associated with significantly decreased biomarkers of inflammation, but not those of oxidative stress and lung function. Air filtration can improve the health of the elderly; air purifiers may be a public health measure to improve circulatory and cardiopulmonary health among older people. Science of the Total Environment PubMed 34325134 10.1016/j.scitotenv.2021.149248 https://pubmed.ncbi.nlm.nih.gov/34325134/
Association between markers of classroom environmental conditions and teachers' respiratory health Claudio L, Rivera GA, Ramirez OF. 2015 Other Linking Gap and Impact Yes N/A Favorable The study found that asthma, respiratory infections, colds, eye irritation, nasal congestion, and sore throat were associated with the classroom environment; results indicate that the school environment could affect teachers' respiratory health. Journal of School Health PubMed 27122144 10.1111/josh.12398 https://pubmed.ncbi.nlm.nih.gov/27122144/
Analysis of changes in pulmonary functions at rest following humidity changes Kim JH, Hyong IH. 2015 Other Linking Intervention and Impact Yes The study examined changes in pulmonary functions at rest after use of a humidifier. The experimental setting was a laboratory with a fixed temperature and relative humidity was adjusted to varying degrees using a humidifier. Favorable The study found that higher humidity levels should be maintained using humidifiers. Journal of Physical Therapy Science PubMed  PMC4433978 10.1589/jpts.27.1063 https://pubmed.ncbi.nlm.nih.gov/25995557/
The New York state healthy neighborhoods program: Findings from an evaluation of a large-scale, multisite, state-funded healthy homes program Reddy AL, Gomez M, Dixon SL. 2017 Other Linking Intervention and Impact Yes The study evaluated the impact of a healthy homes program on improving housing hazards that affect health. The NY State Health Neighborhoods program is a healthy homes program in which participating homes undergo a visual assessment to identify potential environmental health and safety hazards, and interventions (such as education, referrals, and products) are provided to residents to address any hazards identified during the visit. Favorable Homes with the intervention saw significant improvements in the conditions assessed for tobacco control, fire safety, lead poisoning prevention, indoor air quality, and other hazards (including pests and mold). Journal of Public Health Management Practice PubMed 28121773 10.1097/PHH.0000000000000529 https://pubmed.ncbi.nlm.nih.gov/28121773/
Effect of portable air filtration systems on personal exposure to fine particulate matter and blood pressure among residents in a low-income senior facility: A randomized clinical trial Morishita M, Adar SD, D'Souza J, Ziemba RA, Bard RL, Spino C, Brook RD. 2018 Randomized Controlled Trial Linking Intervention and Impact Yes Study examining the effectiveness of air filtration in reducing personal exposures to pollutants and mitigating cardiovascular health effects among older adults in an urban setting. Favorable The study found that the use of these relatively inexpensive systems is potentially cardioprotective against PM2.5 exposures. JAMA Internal Medicine PubMed 30208394 10.1001/jamainternmed.2018.3308 https://pubmed.ncbi.nlm.nih.gov/30208394/
Indoor air quality-induced respiratory symptoms of a hospital staff in Iran Veysi R, Heibati B, Jahangiri M, Kumar P, Latif MT, Karimi A. 2019 Other Linking Gap and Impact Yes N/A Favorable The accumulation of indoor pollutants in the hospital environment revealed the failure of hospital ventilation systems. Laboratory staff members were more at risk of respiratory symptoms compared to other occupational groups in the hospital. Improved ventilation is recommended. Environmental Monitoring and Assessment PubMed 30612195 10.1007/s10661-018-7182-5 https://pubmed.ncbi.nlm.nih.gov/30612195/
Particle control reduces fine and ultrafine particles greater than HEPA filtration in live operating rooms and kills biologic warfare surrogate Ereth MH, Hess DH, Driscoll A, Hernandez M, Stamatatos F. 2020 Other Linking Intervention and Impact Yes A particle control technology was tested to determine its effectiveness at reducing indoor air contamination. Favorable The study found that emerging particle control technology could significantly reduce indoor air contamination and associated infections in operating rooms, hospital isolation rooms, and intensive care settings, as well as reduce inflammatory responses to airborne particles. American Journal of Infection Control PubMed 31911069 10.1016/j.ajic.2019.11.017 https://pubmed.ncbi.nlm.nih.gov/31911069/
Efficacy of indoor air purification in the treatment of artemisia pollen-allergic rhinitis: A randomized, double-blind, clinical controlled trial Li L, Zhang L, Mo JH, Li YY, Xia JY, Bai XB, Xie PF, Liang JY, Yang ZF, Chen QY. 2020 Randomized Controlled Trial Linking Intervention and Impact Yes The study the clinical efficacy of indoor air filtration during the Artemisia pollen scattering season in Yulin City in Shanxi Province, China. Favorable The study found significant differences in rhinitis symptoms between the groups who used the active versus the inactive air purifier, demonstrating the health benefits of particle filtration. Clinical Otolaryngology PubMed 32058675 10.1111/coa.13514 https://pubmed.ncbi.nlm.nih.gov/32058675/
Inflammatory cytokines and DNA methylation in healthy young adults exposure to fine particulate matter: A randomized, double-blind crossover trial of air filtration Sun Y, Huang J, Zhao Y, Xue L, Li H, Liu Q, Cao H, Peng W, Guo C, Xie Y, Liu X, Li B, Liu K, Wu S, Zhang L. 2020 Randomized Controlled Trial Linking Intervention and Impact Yes The experiment evaluated indoor air filtration was conducted among 29 healthy young adults in Beijing, China. Each episode covered a typical air pollution wave, and cytokines and DNAm of genes were measured at 3 time points: pre-smog, during smog, and post-smog. Favorable The study found that indoor air filtration was significantly associated with the decreases in 9 cytokines, demonstrating that indoor air filtration might attenuate the adverse effects of PM2.5 exposure through changing cytokines and DNAm. Journal of Hazardous Materials PubMed 32516725 10.1016/j.jhazmat.2020.122817 https://pubmed.ncbi.nlm.nih.gov/32516725/
Recurrent indoor environmental pollution and its impact on health and oxidative stress of the textile workers in Bangladesh Rahman T, Faisal AM, Khanam T, Shekhar HU. 2020 Other Linking Gap and Impact Yes N/A Favorable The study found that textile plants were found to have significantly elevated levels of indoor environmental pollutants compared with those in the control area, and the textile workers were significantly exposed to oxidative stresses compared with the control subjects. Environmental Health Insights PubMed 32843838  10.1177/1178630220938393 https://pubmed.ncbi.nlm.nih.gov/32843838/
Residential cooking and use of kitchen ventilation: The impact on exposure Sun L, Wallace LA. 2021 Other Linking Gap and Impact Yes N/A Favorable Cooking contributed to PM2.5 exposure in residential settings. The inadequate use of ventilation during cooking highlights the need for educational programs on cooking exposures and ventilation strategies. Journal of Air and Waste Management Association PubMed 32970538 10.1080/10962247.2020.1823525 https://pubmed.ncbi.nlm.nih.gov/32970538/
Health, work performance, and risk of infection in office-like environments: The role of indoor temperature, air humidity, and ventilation Wolkoff P, Azuma K, Carrer P. 2021 Other Linking Gap and Impact Yes N/A Favorable The study found that indoor air humidity causes vulnerable eyes and airways from desiccation and less efficient mucociliary clearance, causing elevation the most common mucous membrane-related symptoms, like dry and tired eyes, which deteriorates the work performance. International Journal of Hygiene and Environmental Health PubMed 33601136 10.1016/j.ijheh.2021.113709 https://pubmed.ncbi.nlm.nih.gov/33601136/
Evaluation of an air cleaning device equipped with filtration and UV: Comparison of removal efficiency on particulate matter and viable airborne bacteria in the inlet and treated air Li P, Koziel JA, Macedo N, Zimmerman JJ, Wrzesinski D, Sobotka E, Balderas M, Walz WB, Paris RV, Lee M, Liu D, Yedilbayev B, Ramirez BC, Jenks WS. 2023 Randomized Controlled Trial Linking Intervention and Impact Yes This experiment used a particulate matter (PM) air filtration prototype by adding UV-C (germicidal) light. Favorable The study found that the combination of filtration and UV-C treatment provided 'double-barrier' assurance for air purification and lowered the risk of spreading infectious micro-organisms. International Journal of Environmental Research and Public Health PubMed 36498208 10.3390/ijerph192316135 https://pubmed.ncbi.nlm.nih.gov/36498208/
Effects of air purification of indoor PM(2.5) on the cardiorespiratory biomarkers in young healthy adults Wang Y, Zhao Y, Xue L, Wu S, Wang B, Li G, Huang J, Guo X. 2021 Randomized Controlled Trial Linking Intervention and Impact Yes Participants were randomly assigned to the use of real or sham high-efficiency particulate air filter (HEPA) for a week and changed the status after a washout period. Favorable The study found a protective effect of indoor HEPA air purifiers on cardiorespiratory health of young healthy adults reflected by the decreased blood pressure, respiratory inflammation, and systematic oxidative stress and improved lung function. Indoor Air PubMed 33682970  10.1111/ina.12815 https://pubmed.ncbi.nlm.nih.gov/33682970/
Home measures against low air humidity which may alleviate health problems Guerra LP, Andrade LMV, Joner DC, Strozzi D. 2021 Randomized Controlled Trial Linking Intervention and Impact Yes Study examining if an air humidifer, bucket of water, or wet towel are most effective in improving the humidity of air in times of drought or low moisture. Favorable The study found that 1m of distance is more efficient in increasing and/or maintaining air humidity, inducing improvements in the populations’ health. Einstein (Sao Paolo) PubMed  34190846 10.31744/einstein_journal/2021AO5484 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8225259/#:~:text=While%20the%20humidity%20is%20below%20the%20ideal%20to,air%20humidifier%2C%20bucket%20with%20water%2C%20and%20wet%20towel.
Indoor air humidity, air quality, and health - an overview Wolkoff P. 2018 Other Linking Gap and Impact Yes N/A Favorable Elevation of the indoor air humidity may positively impact perceived IAQ, eye symptomatology, and possibly work performance in the office environment, and elevated humidified indoor air appears to reduce nasal symptoms in patients suffering from obstructive apnea syndrome. International Journal of Hygiene and Environmental Health PubMed 29398406 10.1016/j.ijheh.2018.01.015 https://pubmed.ncbi.nlm.nih.gov/29398406/
More than a meal? A randomized control trial comparing the effects of home-delivered meals programs on participants' feelings of loneliness Thomas KS, Akobundu U, Dosa D 2016 Randomized Controlled Trial Linking Intervention and Impact Yes The study looked at the impact of Meals on Wheels programs on loneliness in homebound older adults. Yes Favorable The study found that the meal intervention led to lower adjusted loneliness scores in participants compared to the control group. J Gerontol B Psychol Sci Soc Sci Siren 26613620 10.1093/geronb/gbv111 https://pubmed.ncbi.nlm.nih.gov/26613620/
Can tailored home-delivered meal services alleviate self-rated frailty of the low-income older adults in Korea? Kim J, Chang H 2023 Other Linking Intervention and Impact Yes Participants were enrolled in a tailored home-delivered meal program with nutrition counseling Yes Favorable The intervention of home-delivered tailored meals reduced self-rated frailty of aging adults. Nutr Res Pract Google 37780217 10.4162/nrp.2023.17.5.1007 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10522816/
Nutrition: Home-delivered and congregate meal services for older adults 2022 Other Linking Intervention and Impact Grey Literature Participants received delivered meals or participated in congregate meal services in group settings. Yes Favorable The meal service was found to reduce malnutrition among independently living older adults. The Community Guide Preventive Services Task Force for the Department of Health and Human Services Google https://www.thecommunityguide.org/findings/nutrition-home-delivered-and-congregate-meal-services-older-adults.html
The nutritional issue of older people receiving home-delivered meals: A systematic review Fleury S, Tronchon P, Rota J, Meunier C, Mardiros O, Van Wymelbeke-Delannoy V, Sulmont-Rossé C 2021 Systematic Review Linking Intervention and Impact Yes This review included numerous home delivered meal interventions. Yes Favorable Adults who receive home-delivered meals are at a high risk of undernutrition. Home-delivered meals can improve their nutritional status and intake, especially when the intervention includes additional services such as dietetic counseling or adding supplementary food. Front Nutr Google 33763442 10.3389/fnut.2021.629580 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7982843/
Impact of home-delivered meals on nutrition status and nutrient intake among older adults in central Texas Ullevig SL, Sosa ET, Crixell S, Uc E, Greenwald B, Marceaux S, Friedman BJ 2018 Other Linking Intervention and Impact Yes Home delivered meals were delivered to older adults aged 60+ in Austin and San Antonio, Texas for 3 months. Yes Favorable The intervention improved the nutritional status of the adults who received home delivered meals, measured using the Nutrition Screening Initiative and Mini Nutrition Assessment-Short Form. J Nutr Health Aging Google 30080232 10.1007/s12603-018-1038-0 https://pubmed.ncbi.nlm.nih.gov/30080232/
Impact of home-delivered meal programs on diet and nutrition among older adults: A review Zhu H, An R 2013 Systematic Review Linking Intervention and Impact Yes Various home delivered meal programs were included in this review. Yes Favorable Nearly all studies found improvements in diet quality, nutrient intakes, food security, and nutritional risk as a result of the home-delivered meal programs. Other benefits identified were more socialization opportunities, improvement in dietary adherence, and improved quality of life. Nutr Health Google 24916974 10.1177/0260106014537146 https://pubmed.ncbi.nlm.nih.gov/24916974/
Medically tailored meal delivery for diabetes patients with food insecurity: A randomized cross-over trial Berkowitz SA, Delahanty LM, Terranova J, Steiner B, Ruazol MP, Singh R, Shahid NN, Wexler DJ. 2019 Randomized Controlled Trial Linking Intervention and Impact Yes The study analyzed the impact of a medically tailored meal delivery program (Community Servings: Food and Medicine for Diabetes) on food insecurity and dietary quality for individuals with T2D. The program included 10 home-delivered meals per week for 12 weeks. Yes (18+) Diabetes Favorable Participants had higher Health Eating Index 2010 scores (HEI) indicating better dietary quality. Participants also reported lower food insecurity, less hypoglycemia, and fewer days of mental health interfering with quality of life. J Gen Intern Med PubMed 30421335 10.1007/s11606-018-4716-z https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6420590/
Home-delivered meals and nutrition status among older adults Sahyoun NR, Vaudin A. 2014 Other Linking Intervention and Impact Yes This study analyzed the impact of the Older American Act home-delivered meal (HDM) program on health outcomes. Favorable The study found the program improves dietary intake, decreases institutionalization of older adults, and results in reduced healthcare expenditures. Nutr Clin Pract PubMed 25030738 10.1177/0884533614536446 https://pubmed.ncbi.nlm.nih.gov/25030738/
The impact of providing material benefits to improve access to food on clinical parameters, dietary intake, and household food insecurity in people with diabetes: A systematic review with narrative synthesis Jd Steer K, Olstad DL, Jt Campbell D, Beall R, Anstruther SM, Caron-Roy S, Spackman E. 2023 Systematic Review Linking Intervention and Impact Yes The study reviewed the impact of providing material benefits to improve food access for individuals with diabetes. Outcomes included clinical parameters, dietary intake, and household food insecurity. Diabetes Neutral The study found that material benefits may improve household food insecurity, fruit and vegetable intake, and overall diet quality. It was unclear what the impact on clinical parameters and whole grain intake were. Adv Nutr PubMed 37245685 10.1016/j.advnut.2023.05.012 https://pubmed.ncbi.nlm.nih.gov/37245685/
Evaluating the effect of a home-delivered meals service on the physical and psychological wellbeing of a UK population of older adults - a pilot and feasibility study O'Leary MF, Barreto M, Bowtell JL. 2020 Other Linking Intervention and Impact Yes This study evaluated the impact of daily meal provision on the physical and psychological well-being of older adults. Yes Favorable The study found that participants had higher reported Mini Nutritional Assessment (MNA) scores and decreased depression after the intervention. J Nutr Gerontol Geriatr PubMed 31682788 10.1080/21551197.2019.1684417 https://pubmed.ncbi.nlm.nih.gov/31682788/
Effects of home-delivered meals on older people's protein intake, physical performance, and health-related quality of life: The power meals randomized controlled trial Kunvik S, Rautakallio-Järvinen P, Laaksonen M, Valve R, Salonoja M, Fogelholm L, Suominen MH. 2021 Randomized Controlled Trial Linking Intervention and Impact Yes This study looked at the impact of a home meal service intervention on the nutrient intake of older adults living at home. Yes Favorable Protein-rich meal, snack and bread group had increased protein and calcium intake and improved results in Sit-to-Stand test. Both meal services groups had increased saturated fat and decreased salt intake. There was no impact on overall HRQol J Nutr Gerontol Geriatr PubMed 33684023 10.1080/21551197.2021.1892562 https://pubmed.ncbi.nlm.nih.gov/33684023/
Design and rationale of a randomized-controlled trial of home-delivered meals for the management of symptomatic ascites: The SALTYFOOD trial Tapper EB, Baki J, Hummel S, Lok A. 2019 Randomized Controlled Trial Linking Intervention and Impact Yes The study evaluated a home-delivered meal program for patients with cirrhosis and ascites. Favorable Program has potential patient-based benefits, including effective management of ascites, reduction of healthcare utilization and improvement of HRQOL Gastroenterol Rep (Oxf) PubMed 30976428 10.1093/gastro/goz005 https://pubmed.ncbi.nlm.nih.gov/30976428/
The impact of home-delivered meal services on the nutritional intake of community living older adults: A systematic literature review Walton K, do Rosario VA, Pettingill H, Cassimatis E, Charlton K. 2020 Systematic Review Linking Intervention and Impact Yes This study analyzed the impact of a meal service and nutritional intake in community-living older adults. Yes Favorable The study found that the meal intervention had a positive impact on the intake of energy, protein, and/or certain micronutrients in the study population. J Hum Nutr Diet PubMed 31266095 10.1111/jhn.12690 https://pubmed.ncbi.nlm.nih.gov/31266095/
A pilot randomized controlled trial comparing nutritious meal kits and no-prep meals to improve food security and diet quality among food pantry clients Hollis-Hansen K, Haskins C, Turcios J, Bowen ME, Leonard T, Lee M, Albin J, Wadkins-Chambers B, Thompson C, Hall T, Pruitt SL. 2023 Other Linking Intervention and Impact Yes This study compared two approaches of meal kits versus no meal kits to understand how they alleviate barriers for food pantry clients with food insecurity and diet related diseases. Favorable The study found that the nutritious meal kits and no-prep meal kit interventions might increase food security and perceived dietary quality, but the findings were limited due to the sample size. BMC Public Health PubMed 38041070 10.1186/s12889-023-17355-3 https://pubmed.ncbi.nlm.nih.gov/38041070/
A systematic review of behavioral interventions promoting healthy eating among older people Zhou X, Perez-Cueto FJA, Santos QD, Monteleone E, Giboreau A, Appleton KM, Bjørner T, Bredie WLP, Hartwell H. 2018 Systematic Review Linking Intervention and Impact Yes The goal of the study was to understand the impact of a diet intervention for older adults. Yes Favorable Studies demonstrated that multicomponent dietary interventions helped reduce the risk of chronic diseases. Also showed that dietary education or healthier meal services could help older adults have better dietary quality Nutrients PubMed 29373529 10.3390/nu10020128 https://pubmed.ncbi.nlm.nih.gov/29373529/
Home-delivered meals and nursing home placement among people with self-reported dementia: A pilot pragmatic clinical trial Thomas KS, Bunker J, Gadbois E, Hilgeman M, McCreedy E, Mills W, Ornstein KA, Reckrey J, Gutman R. 2023 Other Linking Intervention and Impact Yes This study looked at the impact of home-delivered meals on food security for homebound older adults. Yes No Dementia Neutral Adults with self-reported dementia had a lower likelihood of nursing home placement when receiving daily-delivered meals versus drop-shipped frozen meals, but this was not significant. JAMA Netw Open PubMed 38117500 10.1001/jamanetworkopen.2023.47195 https://pubmed.ncbi.nlm.nih.gov/38117500/
The effect of food is medicine interventions on diabetes-related health outcomes among low-income and food-insecure individuals: A systematic review and meta-analysis Gao Y, Yang A, Zurbau A, Gucciardi E. 2023 Systematic Review Linking Intervention and Impact Yes This systematic review looked at the current literature on the Food is Medicine intervention to understand the impact on diabetes outcomes for low-income or food-insecure individuals. Diabetes Favorable The study found that the Food is Medicine interventions are effective in increasing F&V intake and reducing A1C levels of the target population. More randomized controlled studies are needed to validate the results. Can J Diabetes PubMed 36470724 10.1016/j.jcjd.2022.11.001 https://pubmed.ncbi.nlm.nih.gov/36470724/
The impact of a home-delivered meal program on nutritional risk, dietary intake, food security, loneliness, and social well-being Wright, L., Vance, L., Sudduth, C., & Epps, J. B. 2015 Other Linking Intervention and Impact Yes This pilot study analyzes the impact of the Meals on Wheels delivery service intervention. Yes Favorable The study measures outcomes including nutritional status, dietary intake, well-being, loneliness, and food security levels. Improvements across all five measures were statistically significant after participating two months in the home-delivered meal program J Nutr Gerontol Geriatr Google Scholar https://www.tandfonline.com/doi/abs/10.1080/21551197.2015.1022681
Association of home-delivered meals on daily energy and nutrient intakes: Findings from the National Health and Nutrition Examination Surveys An, R. 2015 Other Linking Intervention and Impact Yes This study looked at the impact of a home delivered meal program on energy and nutrient intake. Favorable Services were associated with increased intake of protein, fiber, calcium, copper, magnesium, potassium, selenium, and sodium. There was no significant difference in intake of total energy, fat, and vitamin D. J Nutr Gerontol Geriatr Google Scholar https://www.tandfonline.com/doi/abs/10.1080/21551197.2015.1031604
Impact of vegan meal kits on cardiometabolic endpoints: A randomized, controlled clinical trial Pham, K., Sky, J., Hill, R., Haynes, A., Pak, S., & Shah, S. A. 2022 Randomized Controlled Trial Linking Intervention and Impact Yes This study analyzed the difference in the impact of a vegan boxed meal kit (VBK) and a standard omnivorous boxed meal kit (OBK) on cardiometabolic endpoints. Favorable The study found that the VBK significantly reduced LDL-c and weight in a 4-week period. Circulation Google Scholar https://www.ahajournals.org/doi/abs/10.1161/circ.146.suppl_1.15086
Effective elements of home-delivered meal services to improve energy and protein intake: A systematic review IJmker-Hemink, V. E., Dijxhoorn, D. N., Ozumbilla, C. M. B., Wanten, G. J., & van den Berg, M. G. 2020 Systematic Review Linking Intervention and Impact Yes The study looked at the impact of home-delivered meal services on energy and protein intake, nutritional status, functional outcomes, and satisfaction in adults. Favorable The study found that several elements of the MOW intervention positively impacted outcomes like energy and protein intake and satisfaction. Nutrition Google Scholar https://www.sciencedirect.com/science/article/pii/S0899900719300917
Health economic benefits from optimized meal services to older adults—a literature-based synthesis Jensen, J. D. 2021 Other Linking Intervention and Impact Yes This study looks at the economic impact of meal service interventions on home-dwelling older adults. Favorable The study estimated economic benefits in terms of saved direct and indirect health care costs and improved quality-of-life of €307 per year per individual enrolled. Direct health care cost savings were €75. The remainder was due to improved quality-of-life and reduced mortality. European Journal of Clinical Nutrition Google Scholar https://www.nature.com/articles/s41430-020-00700-9
Aging in america and meals on wheels: Exploring impacts on food insecurity, health outcomes, and hospitalizations Som, V., Yee-Melichar, D., & Zernicke, M. L. 2018 Other Linking Intervention and Impact Yes This study look the impact of MOW services on health outcomes, hospitalizations, and food insecurity. Favorable The study found that survey respondents had high levels of self-reported health improvement and low levels of food insecurity after the MOW intervention. Findings suggest there are improved health outcomes and a decrease in hospitalizations as MOW participation length increases. Trends Geriatr Healthc Google Scholar https://scholars.direct/Articles/geriatric-medicine/tghc-1-003.php?jid=geriatric-medicine
Association of national expansion of insurance coverage of medically tailored meals with estimated hospitalizations and health care expenditures in the US Hager K, Cudhea FP, Wong JB, Berkowitz SA, Downer S, Lauren BN, Mozaffarian D 2022 Other Linking Intervention and Impact Yes This study looks at the impact of medically tailored meals on hospitalizations, health care expenditures, and overall policy cost-effectiveness. Favorable The study found that medically tailored meals could be associated with approximately 1.6 million averted hospitalizations and net cost savings of $13.6 billion annually for individuals with die-sensitive conditions or activity limitations. JAMA Netw Open Siren 36251292 10.1001/jamanetworkopen.2022.36898 https://pubmed.ncbi.nlm.nih.gov/36251292/
Meal delivery programs reduce the use of costly health care in dually eligible Medicare and Medicaid beneficiaries Berkowitz SA, Terranova J, Hill C, Ajayi T, Linsky T, Tishler LW, DeWalt DA 2018 Prospective Cohort Study Linking Intervention and Impact Yes This study looks at the impact of home delivery of either medically tailored meals or nontailored food on social determinants of health. Yes Favorable The study found that both intervention types led to few fewer emergency department visits. The medically tailored meal program also had fewer inpatient admissions and lower medical spending. The nontailored food program was not associated with fewer inpatient admissions but was associated with lower medical spending. Health Aff (Millwood) Siren 29608345 10.1377/hlthaff.2017.0999 https://pubmed.ncbi.nlm.nih.gov/29608345/
Anti-inflammatory kitchen kit: Delivering foods for chronic pain to the patient's kitchen Feldman-Hunt, C., & Clairmont, E. 2022 Prospective Cohort Study Linking Intervention and Impact Grey Literature The 13-week intervention consisted of provision of an Anti-Inflammatory Pantry Kit to participants, containing health and nutritious foods and meetings with registered dieticians. Favorable This intervention resulted in modifications to participant diets to increase whole food sources of essential nutrients that are evidenced to affect inflammation and immune system function among people with chronic pain. Conference: International Congress on Integrative Health and Medicine Google Scholar https://www.researchgate.net/publication/361004543_ANTI-INFLAMMATORY_PANTRY_KIT_DELIVERING_FOODS_FOR_CHRONIC_PAIN_TO_THE_PATIENT%27S_KITCHEN_Anti-_Inflammatory_Diet_Nutrient_Balance_Reduce_Inflammatory_Foods_Eat_Anti-Inflammatory_Foods_Eliminate_Food_In
Food pantry-based intervention may help improve diabetes self-management in low socioeconomic status individuals: A narrative review Collins, N., Krutee, L., Bidaisee, S. 2022 Other Linking Intervention and Impact Yes This study looked at the literature to understand the impact of food pantries on diabetes mellitus self-management. Favorable The literature review found a relationship between food insecurity and diabetes mellitus management and glycemic control. The review found mixed results for the impact of interventions on self-management. International Public Health Journal Google Scholar https://www.proquest.com/docview/2679853796?sourcetype=Scholarly%20Journals
Ensuring food security for cancer patients may improve cancer outcomes Dikmen, D. 2023 Randomized Controlled Trial Linking Intervention and Impact Yes The study looked at food insecurity interventions and their impact on cancer outcomes. The intervention included a hospital cancer clinic–based food pantry, food voucher plus pantry, and home grocery delivery plus pantry. Cancer Favorable The study found the voucher plus pantry to be most effective for treatment completion. All three interventions were promising in improving food insecurity in the patient population. Komp Nutr Diet Google Scholar https://doi.org/10.1159/000529397 https://karger.com/knd/article/3/1/16/834913/Ensuring-Food-Security-for-Cancer-Patients-may
Impact of the SARS-CoV-2 pandemic and a food pantry on food insecurity in a pediatric cystic fibrosis center Holzum, H., Nelson, K., Granneman, J., Acton, J., & Nevel, R. 2021 Other Linking Intervention and Impact Yes The study analyzed the impact of a food pantry for families in a pediatric CF center to understand the impact on food insecurity. No Yes Favorable The food pantry led to a decrease from 27% to 13% in at-risk nutritional status in the study participants. Journal of Cystic Fibrosis Google Scholar PMC8518436 10.1016/S1569-1993(21)01767-7 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8518436/
Reducing diabetes prevalence in food pantry patrons using an adapted CDC CHANGE tool for policy, systems, and environmental change Geraghty, B., AE-C, M. B., Lewis, S., Charters, M., Romero, M., Maduka, J., Angeles, N., Olivares, P., & Sheely, S. 2019 Other Linking Intervention and Impact Grey Literature This study analyzed the impact of an adapted CHANGE tool to improve the nutritional content of a food pantry, and its impact on individuals with, or at risk of, diabetes. Diabetes Favorable The study found that pantry staff chose healthier options than clients and did not believe in the client's ability to choose healthier options. They also found that most clients would choose healthier options if they were offered. APHA's 2019 Annual Meeting and Ecpo Google Scholar https://apha.confex.com/apha/2019/meetingapi.cgi/Paper/438108?filename=2019_Abstract438108.html&template=Word
The food pharmacy network: An alternative method for addressing food insecurity and an assessment of its effectiveness (OR02-08-19) Wang, E. Gilbert, A., Mueller, S., Wessels, A. 2019 Other Linking Intervention and Impact Yes This study analyzed the impact of "The Food Pharmacy Network" intervention that provides free fresh produce in health clinics on food security. Favorable The study found that The Food Pharmacy Network participants were less likley to experience very low food securty, increased self suffiency and increased fruits and vegetable serving sper day versus the control group. Curr Dev Nutr Google Scholar https://doi.org/10.1093/cdn/nzz051.OR02-08-19 https://www.sciencedirect.com/science/article/pii/S2475299123158537
Does fresh food improve health? Expanding the care delivery boundary in partnership models of care Lowrey, J., Chandrasekaran, A., Headings, A., Hyder, A. 2021 Other Linking Intervention and Impact Grey Literature This study looked at the impact of the Mid-Ohio Farmacy program on health quality and cost. The intervention assesses the food status of patients to help refer them to food pantries. Favorable The study found the intervention let to a 3% decrease in weight and 10% reduction in costs. Google Scholar https://papers.ssrn.com/sol3/papers.cfm?abstract_id=3747816
Cardiometabolic impacts of a large-scale, partnership-based regional food prescription program Ranjit, N., McWhorter, J., Boyer, P., & Sharma, S. 2022 Other Linking Intervention and Impact Grey Literature The study looked at the impact of a food prescription program on cardiometabolic measures. Favorable The study found that the intervention led to a decline in HbA1c in participants. There were also differences seen in systolic and diastolic blood pressure between the study groups. APHA 2022 Annual Meeting and Expo Google Scholar https://apha.confex.com/apha/2022/meetingapi.cgi/Paper/518816?filename=2022_Abstract518816.pdf&template=Word
Impact of a fruit and vegetable prescription program on diet quality and cardio-metabolic risk factors in healthy adults in a worksite setting: A randomized controlled trial (OR16-07-19) Comerford, B., Doughty, K., Njike, V., Ayettey, R., Weisel, A., Katz, D., & Costales, V. 2019 Randomized Controlled Trial Linking Intervention and Impact Yes This study looked at the impact of the Fruit and Vegetable "Presciption" (FVRx) intervention. The intervention included 45-minute cooking and nutrition education sessions and a $15-25 voucher for fruit and vegetables. Yes (18+) Diabetes Neutral The study found that the FVRx intervention led to an increase in HEI-2010 scores (vegetable intake) and reduced HE-2010 scores (empty calories). There was no significant difference in body composition, HbA1c blood lipids, or blood pressure. BMC Public Health Google Scholar https://doi.org/10.1093/cdn/nzz051.OR16-07-19 https://www.sciencedirect.com/science/article/pii/S2475299123158598
A clinical-community partnership to address food insecurity and reduce emergency department utilization among Medicaid-insured patients in North Carolina Mayfield, C., Robinson-Taylor, T., Rifkin, D., Harris, ME. 2024 Other Linking Intervention and Impact Yes This study looked at the impact of a food prescription program. Yes (18+) Favorable The study found that the intervention led to a decrease in nonadmission ED utilization, Journal of Public Health Management and Practice Google Scholar 37646558 10.1097/PHH.0000000000001821 https://pubmed.ncbi.nlm.nih.gov/37646558/
Healthy food delivery for type 2 diabetes management in rural clinics' patients: A comparative effectiveness randomized controlled trial protocol Short E, Selig JP, Felix HC, Painter J, McElfish PA, Rowland B, Ammerman AS, Bounds K, Henske J, Hudson JS, Li J, Young SG, Long CR. 2024 Randomized Controlled Trial Linking Intervention and Impact Yes This study looked at the impact of a delivered food box that is specific for individuals with type 2 diabetes melllitus. The intervention included 3 months of delivered meals and a 60 minute vitual consultation. Dementia Favorable The study does not currently have findings on HbA1c changes or diet quality. Contemp Clin Trials PubMed 38458560 10.1016/j.cct.2024.107491 https://pubmed.ncbi.nlm.nih.gov/38458560/
Campus food pantry use is linked to better health among public university students Martinez SM, Chodur GM, Esaryk EE, Kaladijian S, Ritchie LD, Grandner M. 2022 Other Linking Intervention and Impact Yes The study looked at the impact of a campus food pantry (CFP) intervention on college students. No Yes Mental Health Favorable The study measured sleep, mental health, and physical health outcomes. They found decreased depression symptoms, improved sleep sufficiency, and improved percieved health. J Nutr Educ Behav PubMed 35618403 10.1016/j.jneb.2022.03.001 https://pubmed.ncbi.nlm.nih.gov/35618403/
Community-based fruit and vegetable prescription programs: A scoping review Greatorex Brooks E, McInerney M. 2023 Other Linking Intervention and Impact Yes The study intervention of interest is a community-based fruit and vegetable prescription boxes program, and its impact on various measures. Favorable Studies found diet quality, health outcomes, and food insecurity status imroved. J Nutr Sci PubMed 37744640 10.1017/jns.2023.81 https://pubmed.ncbi.nlm.nih.gov/37744640/
Assessing the effect of adverse economic events on severity of hunger among food pantry clients Bangham C, Zack RM, Nelson E, Liu X, Codner A, Hicks JM, Greece JA. 2023 Other Linking Gap and Impact Yes N/A Yes Yes Favorable Hunger was found to be associated with increased medical expenses, job loss, pay reduction, increased debt, and death of a family member Front Public Health PubMed 38026276 10.3389/fpubh.2023.1286094 https://pubmed.ncbi.nlm.nih.gov/38026276/
Participant perceptions of a free fresh produce market at a health center Dunn CG, Vercammen KA, Bleich SN, Mulugeta W, Granick J, Carney C, Zack RM. 2021 Other Linking Intervention and Impact Yes This study looked at a free, monthly produce market intervention to understand its impact and barriers to access. Yes Yes Favorable Participants reported facilitators or the market were accessibility program experience, and the qualities of goods and servcies. Reported barriers included transportation challenes, weather, and not enough produce. They reported the market improved diet and finances. J Nutr Educ Behav PubMed 34246412 10.1016/j.jneb.2021.03.012 https://pubmed.ncbi.nlm.nih.gov/34246412/
Food security and clinical outcomes of the 2017 Georgia fruit and vegetable prescription program Cook M, Ward R, Newman T, Berney S, Slagel N, Bussey-Jones J, Schmidt S, Sun Lee J, Webb-Girard A. 2021 Other Linking Intervention and Impact Yes The study looked at a six-month intervention for group-based nutrition and cooking education. Additionally, it included subsidies for fresh produce. Yes Yes Favorable The study found a significant decrease of food insecurity and blood pressure from participation in the program. J Nutr Educ Behav PubMed 34509277 10.1016/j.jneb.2021.06.010 https://pubmed.ncbi.nlm.nih.gov/34509277/
Food as medicine clinic: Early results and lessons learned Hu D, Cherian A, Chagin K, Bier J, Einstadter D, Gunzler D, Glenn A, McLaughlin E, Cook K, Misak J, Bolen SD. 2022 Other Linking Intervention and Impact Yes The study analyzed the impact of a hospital-based food pantry clinic, which included a 3-day supply of food up to 2 times a month, up to 12 months. The impacts observed included self-reported dietary changes, health outcomes, and resource utilization. Yes Yes (18+) Neutral The program led to self-reported improvement in dietary behavior but did not have significant changes in clinical or healthcare utilization measures. Cureus PubMed 36579189 10.7759/cureus.31912 https://pubmed.ncbi.nlm.nih.gov/36579189/
Effect of an intensive food-as-medicine program on health and health care use: A randomized clinical trial Doyle J, Alsan M, Skelley N, Lu Y, Cawley J. 2024 Randomized Control Trial Linking Intervention and Impact Yes This study looked at the food-as-medicine program to understand its impact on a patients with diabetes. Yes Yes Neutral The study measures outcomes including HbA1c level at 6 months, other biometric measures, health care use, self-reported diet, and healthy behaviors. The study found increased engagement with preventive health care, but did not find a significant difference in HbA1c levels. but no improvement in glycemic control JAMA Intern Med PubMed 38147326 10.1001/jamainternmed.2023.6670 https://pubmed.ncbi.nlm.nih.gov/38147326/
Evaluating the benefits of a SNAP-Ed-funded community garden intervention using ripple effect mapping Sadeghzadeh C, Sheppard B, de Groot J, De Marco M. 2022 Other Linking Intervention and Impact Yes Study to understand the impact of a community garden program funded by SNAP-Edusing the Ripple Effect Mapping (REM) method. Neutral The study takeaway was on the REM method and found it was a useful way to study the impact of programs such as SNAP-Ed. Health Educ Behav PubMed 34963366 10.1177/10901981211058075 https://pubmed.ncbi.nlm.nih.gov/34963366/
Veggie Rx: an outcome evaluation of a healthy food incentive programme Cavanagh M, Jurkowski J, Bozlak C, Hastings J, Klein A. 2017 Other Linking Intervention and Impact Yes This study evaluates the Veggie Rx intervention which is a healthy food incentive program in upstate New York. Favorable The Veggie Rx program showed a statistically significant improvement in mean BMI between study groups. Public Health Nutr PubMed 27539192 10.1017/S1368980016002081 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5743436/
A mixed-methods examination of the impact of the partnerships to improve community health produce prescription initiative in northeastern North Carolina Lyonnais MJ, Kaur AP, Rafferty AP, Johnson NS, Jilcott Pitts S. 2022 Other Linking Intervention and Impact Yes The study looked at the impact of produce prescription vouchers. Favorable The study found that the voucher initiative resulted in increased fruit and vegetable purchasing and consumption. J Public Health Manag Pract PubMed 35121710 10.1097/PHH.0000000000001490 https://pubmed.ncbi.nlm.nih.gov/35121710/
Buying health: Assessing the impact of a consumer-side vegetable subsidy on purchasing, consumption and waste Smith-Drelich N. 2016 Randomized Controlled Trial Linking Intervention and Impact Yes The study looked at the impact of a reimbursement-based consumer subsidy. Outcomes measures included vegetable expenditures, consumption and waste. No Yes Unfavorable The study found that the intervention increased vegetable expenditure but did not have an impact on vegetable consumption. Public Health Nutr PubMed 26054549 10.1017/S1368980015001469 https://pubmed.ncbi.nlm.nih.gov/26054549/
The effectiveness of nutritional interventions in malnutrition and cachexia Baldwin C. 2015 Systematic Review Linking Intervention and Impact Yes The purpose of this study was to understand the current oral nutritional interventions related to weight loss in cancer patients. Neutral The study found that existing oral nutritional intervention studies have had limited evidence on the benefit to clinical outcomes from these interventions. They have shown increases in quality of life. Proc Nutr Soc PubMed 26087760 10.1017/S0029665115002311 https://pubmed.ncbi.nlm.nih.gov/26087760/
A systematic review of food pantry-based interventions in the USA An R, Wang J, Liu J, Shen J, Loehmer E, McCaffrey J. 2019 Systematic Review Linking Intervention and Impact Yes The purpose of this study was to understand the literature on food-pantry-based interventions and the effect of this type of program in the US. Favorable Articles used in the study found that food pantry interventions did have a positive impact on diet-related outcomes. Public Health Nutr PubMed 30834852 10.1017/S1368980019000144 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10260889/
Food to overcome outcomes disparities: A randomized controlled trial of food insecurity interventions to improve cancer outcomes Gany F, Melnic I, Wu M, Li Y, Finik J, Ramirez J, Blinder V, Kemeny M, Guevara E, Hwang C, Leng J. 2022 Randomized Controlled Trial Linking Intervention and Impact Yes This study looked at the impact of food insecurity interventions on cancer outcomes Yes Yes Cancer Favorable The study found the voucher plus pantry intervention had the highest treatment completion rate and was most effective at improving treatment completion. The three interventions also indicated a potential to improve food security among the medically underserved. J Clin Oncol PubMed 35709430 10.1200/JCO.21.02400 https://pubmed.ncbi.nlm.nih.gov/35709430/
The impact of providing material benefits to improve access to food on clinical parameters, dietary intake, and household food insecurity in people with diabetes: a systematic review with narrative synthesis Jd Steer K, Olstad DL, Jt Campbell D, Beall R, Anstruther SM, Caron-Roy S, Spackman E. 2023 Systematic Review Linking Intervention and Impact Yes This study looked at how material food benefits impacted access, dietary intake, and food insecurity for individuals with diabetes and any relevant economic evidence. Diabetes Neutral Literature showed improved household food insecurity, fruit and vegetable intake, and overall diet quality with interventions aimed at improving access to food for people with diabetes. It was not clear if it impacted clinical parameters and whole grain intake. Adv Nutr PubMed 37245685 10.1016/j.advnut.2023.05.012 https://pubmed.ncbi.nlm.nih.gov/37245685/
Randomised controlled trial testing the feasibility of an exercise and nutrition intervention for patients with ovarian cancer during and after first-line chemotherapy (BENITA-study) Maurer T, Belau MH, von Grundherr J, Schlemmer Z, Patra S, Becher H, Schulz KH, Zyriax BC, Schmalfeldt B, Chang-Claude J. 2022 Randomized Controlled Trial Linking Intervention and Impact Yes The study looked at a nutrition and exercise intervention to determine its safety and efficacy for patients with ovarian cancer. Yes (18+) Cancer Favorable The study showed that the intervention was safe and will analyze the effectiveness of the intervention in a future RCT. BMJ Open PubMed 35197344 10.1136/bmjopen-2021-054091 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8867313/
Application of food exchange portion method in home-based nutritional intervention for elderly patients with chronic heart failure Zhou C, Wang S, Sun X, Han Y, Zhang L, Liu M. 2023 Randomized Controlled Trial Linking Intervention and Impact Yes This study analyzes a home-based nutritional intervention for elderly patients with chronic heart failure and its impact on nutritional status. Yes No Chronic Heart Failure Favorable This study found that the intervention positively impacted the nutritional status of individuals with CHF. There was significant and positive impact on nutritional indexes and cardiopulmonary function indexes for the experimental group. BMC Cardiovasc Disord PubMed 36765270 10.1186/s12872-023-03072-7 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9912658/
The effectiveness of nutrition interventions combined with exercise in upper gastrointestinal cancers: a systematic review Sadeghi F, Mockler D, Guinan EM, Hussey J, Doyle SL. 2021 Systematic Review Linking Intervention and Impact Yes The study aimed to understand the impact of combined nutritional and exercise interventions on patients with GI cancer. Yes (18+) Cancer Neutral Studies showed promising but insignificant effects on physical functioning and conflicting results on muscle mass and improving health-related quality of life from nutrition and exercise interventions. Nutrients PubMed 34445002 10.3390/nu13082842 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8400981/
A systematic review of interventions that address food insecurity for persons with prediabetes or diabetes using the RE-AIM framework Whitehouse CR, Akyirem S, Petoskey C, Huang S, Lendvai D, Batten J, Whittemore R. 2024 Systematic Review Linking Intervention and Impact Yes This study looked at two interventions (a medically tailored meal/grocery program and produce prescriptions/vouchers and their impact on food insecurity for individuals with prediabetes or T2D. Yes (18+) Diabetes Favorable Studies showed a decrease in A1C, improved self-management, self-efficacy, depressive symptoms/diabetes distress, and quality of life. Some studies reported statistically significant improvements in food insecurity. Sci Diabetes Self Manag Care PubMed 38545669 10.1177/26350106241232649 https://pubmed.ncbi.nlm.nih.gov/38545669/
Comprehensive diabetes self-management support from food banks: A randomized controlled trial Seligman HK, Smith M, Rosenmoss S, Marshall MB, Waxman E. 2018 Randomized Controlled Trial Linking Intervention and Impact Yes The purpose of this study was to understand the impact of food bank provision of self-management support and diabetes-appropriate on glycemic control for individuals with diabetes. Yes (18+) Diabetes Favorable Food security, food stability, and fruit and vegetable intake significantly improved in participants, but there was no significant difference in self-management or HbA1c. Am J Public Health PubMed 30024798 10.2105/AJPH.2018.304528 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6085038/
Reductions in housing benefit increases symptoms of depression in low-income UK households Reeves A, McKee M, Clair A, Stuckler D 2016 Other Linking Gap and Impact Yes N/A Favorable Results found that depressive symptoms increased in renters after experiencing cuts to housing benefits. There is evidence to support that reducing housing support to low-income individuals worsens mental health. European Journal of Public Health Google Scholar https://doi.org/10.1093/eurpub/ckw172.053 https://academic.oup.com/eurpub/article/26/suppl_1/ckw172.053/2449039
Association between rental assistance programs and hemoglobin A1c levels among US adults Fenelon A, Lipska KJ, Denary W, Blankenship KM, Schlesinger P, Esserman D, Keene DE. 2022 Prospective Cohort Study Linking Intervention and Impact Yes The study included two types of federal rental assistance programs: project-based housing and housing vouchers. No 45+ Diabetes Favorable The authors found an association between project-based housing and a reduced likelihood of the participant having uncontrollable diabetes, compared to participants in the waitlist group receiving no benefits. Participants in project-based housing had lower HbA1c levels compared to individuals receiving no assistance, but this finding was not significant. JAMA Netw Open PubMed 35857325 10.1001/jamanetworkopen.2022.22385 https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2794445
Reductions in the United Kingdom's government housing benefit and symptoms of depression in low-income households Reeves A, Clair A, McKee M, Stuckler D. 2016 Other Linking Intervention and Impact Yes UK government's reduction of financial housing support in April 2011 for low-income households who rent. private-sector housing No Favorable Depressive symptoms among individuals receiving housing assistance increased by 1.8% after the change in UK government policy compared to individuals not receiving assistance. Am J Epidemiol PubMed 27613659 10.1093/aje/kww055 https://pubmed.ncbi.nlm.nih.gov/27613659/
Housing status, medical care, and health outcomes among people living with HIV/AIDS: A systematic review Aidala AA, Wilson MG, Shubert V, Gogolishvili D, Globerman J, Rueda S, Bozack AK, Caban M, Rourke SB. 2016 Systematic Review Linking Gap and Impact Yes N/A HIV/AIDS Favorable Almost all of the studies included in review demonstrated that poorer housing status was associated with poorer outcomes, including adherence to antiretroviral medications, access and utilization of HIV medical care, HIV clinical outcomes, ED and inpatient utilization, sex and drug risk behaviors, and other health outcomes. Am J Public Health PubMed 26562123 10.2105/AJPH.2015.302905 https://pubmed.ncbi.nlm.nih.gov/26562123/
Impact of the monetary value of housing assistance on adult health outcomes Byrne T, Miller DP, Thomas MMC. 2023 Other Linking Intervention and Impact Yes The intervention was federal low-income housing assistance. No Neutral The authors did not find substantial evidence that the value of housing assistance impacts overall health or outcomes. They did determine that the impact on health likely depends on the value of the housing assistance, where greater assistance frees up more resources to spend on other needs. Health Serv Res PubMed 37248792 10.1111/1475-6773.14174 https://pubmed.ncbi.nlm.nih.gov/37248792/
HUD housing assistance associated with lower uninsurance rates and unmet medical need Simon AE, Fenelon A, Helms V, Lloyd PC, Rossen LM. 2017 Other Linking Intervention and Impact Yes The intervention was US Department of Housing and Urban Development housing assistance. No Yes Favorable The authors found that receiving HUD assistance was associated with lower uninsurance rates and rates of unmet health care needs due to cost. Health Aff (Millwood) PubMed 28583959 10.1377/hlthaff.2016.1152 https://pubmed.ncbi.nlm.nih.gov/28583959/
The association of broadband internet access and telemedicine utilization in rural western Tennessee: An observational study Quinton JK, Ong MK, Vangala S, Tetleton-Burns A, Webb A, Sarkisian C, Casillas A, Kakani P, Han M, Pirtle CJ. 2021 Other Linking Intervention and Impact Yes The intervention of interest was access to broadband internet by zip code. No Favorable Access to broadband internet was associated with the utilization of telemedicine services among a rural, working-class community. BMC Health Serv Res PubMed 34344377 10.1186/s12913-021-06746-0 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8329625/
The impact of temporary housing assistance expenditures on subcategories of health care cost for U.S. veterans facing housing instability Nelson RE, Montgomery AE, Suo Y, Cook J, Pettey W, Evans W, Greene T, Gelberg L, Kertesz S, Tsai J, Byrne T. 2022 Other Linking Intervention and Impact Yes Temporary financial assistance for housing-related expenses from the US Department of Veterans Affairs was the intervention. No Favorable Temporary financial assistance was found to decrease healthcare costs in ED, outpatient mental health, outpatient substance use disorder treatment, inpatient mental health, and residential behavioral health. J Health Care Poor Underserved PubMed 36341665 10.1353/hpu.2022.0140 https://pubmed.ncbi.nlm.nih.gov/36341665/
Housing instability and socioeconomic disparities in health: Evidence from the U.S. economic recession Wang K 2021 Other Linking Gap and Impact Yes N/A Favorable This article focuses on the relationship between housing instability and health outcomes, including heart disease and mental health conditions, particularly focusing on variations among racial and income groups. It found that housing instability was strongly associated with heart disease and mental health conditions. Journal of Racial and Ethnic Health Disparities Google Scholar 34837164 https://doi.org/10.1007/s40615-021-01181-7 https://link.springer.com/article/10.1007/s40615-021-01181-7
Neighborhood broadband and use of telehealth among older adults: Cross-sectional study of national survey data linked with census data Okoye SM, Mulcahy JF, Fabius CD, Burgdorf JG, Wolff JL. 2021 Other Linking Gap and Impact Yes N/A Yes Favorable Broadband internet access was associated with engagement in telehealth. J Med Internet Res PubMed 34125071 10.2196/26242 https://pubmed.ncbi.nlm.nih.gov/34125071/
The effect of unstable housing on HIV treatment biomarkers: An instrumental variables approach Galárraga O, Rana A, Rahman M, Cohen M, Adimora AA, Sosanya O, Holman S, Kassaye S, Milam J, Cohen J, Golub ET, Metsch LR, Kempf MC. 2018 Other Linking Gap and Impact Yes N/A No HIV/AIDS Favorable Unstable housing was found to reduce the likelihood of viral suppression and the probability of having adequate CD4 cell count. Soc Sci Med PubMed 30153546 10.1016/j.socscimed.2018.07.051 https://pubmed.ncbi.nlm.nih.gov/30153546/
Effects of housing vouchers on the long-term exposure to neighborhood opportunity among low-income families: The moving to opportunity experiment Kim H, Schmidt NM, Osypuk TL, Thyden N, Rehkopf D. 2023 Prospective Cohort Study Linking Intervention and Impact Yes Tenant-based voucher program from the Moving to Opportunity experiment was used. No Favorable Recipients of the vouchers experienced improvements in neighborhood opportunity overall and in social/economic, educational, and health/environmental domains. Hous Stud PubMed 36861113 10.1080/02673037.2022.2112154 https://pubmed.ncbi.nlm.nih.gov/36861113/
Formerly homeless and other stakeholder perspectives of a permanent supportive housing program in Los Angeles County Kietzman K, Palimaru A, Basurto-Davila R, Pourat N 2020 Other Linking Intervention and Impact Yes Housing for Health, an initiative in Los Angeles County providing permanent supportive housing and rental subsidies and intensive case management to high utilizer unhoused individuals. No Favorable The authors recorded positive impacts of the program as it expanded the reach and intensity of permanent supportive housing and enhanced continuity of care. Health Serv Res Google Scholar 10.1111/1475-6773.13523 https://onlinelibrary.wiley.com/doi/abs/10.1111/1475-6773.13523
Health outcomes of obtaining housing among older homeless adults Brown RT, Miao Y, Mitchell SL, Bharel M, Patel M, Ard KL, Grande LJ, Blazey-Martin D, Floru D, Steinman MA 2015 Prospective Cohort Study Linking Gap and Impact Yes N/A Yes Favorable Participants who obtained housing over the study period had fewer depressive symptoms and a lower rate of acute care use compared to participants who remained homeless. Amer J Pub Health Google Scholar 25973822 10.2105/AJPH.2014.302539 https://ajph.aphapublications.org/doi/abs/10.2105/AJPH.2014.302539
Broadband internet access improves health outcomes for Medicare patients Vasquez L 2023 Other Linking Intervention and Impact Gray Literature Broadband internet access is the intervention studied. Yes Favorable Reliable broadband access is associated with better outcomes for planned procedures and provides patients the opportunity to research and gather information relating to their medical conditions and decisions. NBER Bulletin on Health Google Scholar https://go.gale.com/ps/i.do?p=AONE&u=anon~f001c431&id=GALE|A775356061&v=2.1&it=r&sid=googleScholar&asid=9ba99895.
Digital access: A super determinant of health Turcios Y 2023 Federal Policy or Report Linking Gap and Impact Grey Literature N/A Favorable Internet access has a significant part in health care outcomes and can be used to reduce disparities in health care access and health outcomes. SAMHSA Google Scholar https://connect.extension.org/g/health-and-well-being/fileSendAction/fcType/5/fcOid/556965987635340010/fodoid/556965987635340006/Digital%20Access_%20A%20Super%20Determinant%20of%20Health%20_%20SAMHSA.pdf
Older adults and mobile phones for health: A review Joe J, Demiris G 2013 Systematic Review Linking Intervention and Impact Yes The study examines the use of mobile phones in health interventions for older adults and their level of effectiveness. Yes Favorable There is significant variability in the current research, but there is documented evidence that the use of mobile phones in care for older adults can improve clinical outcomes and promote follow up. J Biomed Inform Google 23810858 10.1016/j.jbi.2013.06.008 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3836587/
US counties with low broadband internet access have a high burden of cardiovascular risk factors, disease, and mortality Troy A, Xu J, Wadhera R 2022 Other Linking Intervention and Impact Yes This study examines the relationship between broadband access by county and cardiovascular risk factors, disease, and mortality. No Favorable Counties with poor broadband access have significantly higher rates of CVD, CVD risk factors, and CVD mortality, in addition to poorer access to physicians. AHA Journals Google Scholar 10.1161/circ.146.suppl_1.10423 https://www.ahajournals.org/doi/abs/10.1161/circ.146.suppl_1.10423
Housing need, housing assistance, and connecting to HIV medical care Aidala AA, Lee G, Abramson DM, Messeri P, Siegler, A 2007 Other Linking Gap and Impact Yes N/A HIV/AIDS Favorable Results found a strong relationship between housing need and poor HIV care engagement. Additionally, receiving housing assistance increased access and retention to HIV care. Study provides strong evidence that housing needs are a significant barrier to consistent inappropriate HIV medical care and that housing assistance directly improves health care outcomes. AIDS and Behavior Google Scholar https://doi.org/10.1007/s10461-007-9276-x https://pubmed.ncbi.nlm.nih.gov/17768674/
Reducing homelessness by embracing housing as a Medicaid benefit Bamberger J 2016 Other Linking Intervention and Impact Yes This article relays literature that loss of housing is associated with poorer health and increased acute care utilization. HIV/AIDS Favorable The author summarizes literature that housing may improve health. In one study, placing people experiencing homelessness in permanent supportive housing was associated with an 80% decrease in mortality among homeless adults with AIDS. JAMA Internal Medicine Google Scholar 10.1001/jamainternmed.2016.2615 https://pubmed.ncbi.nlm.nih.gov/27322820/
Impact of supported housing on clinical outcomes: Analysis of a randomized control trial using multiple imputation technique Cheng A, Lin H, Kasprow W, Rosenheck RA 2007 Randomized Controlled Trial Linking Intervention and Impact Yes The authors evaluated the US Housing and Urban Development and Department of Veterans Affairs Supportive Housing Program, including Section 8 housing vouchers, which provided rent subsidies for low-income individuals with disabilities. Favorable The study found benefits among the study population in terms of psychiatric and substance use disorders, including drug and alcohol abuse. https://doi.org/10.1097/01.nmd.0000252313.49043.f2 https://pubmed.ncbi.nlm.nih.gov/17220745/
Association of advance care planning with place of death and utilization of life-sustaining treatments in deceased patients at Taipei City Hospital in Taiwan Yen YF, Lee YL, Hu HY, Sun WJ, Ko MC, Chang SS, Chen CC, Huang SJ, Chu D. 2020 Prospective Cohort Study Linking Intervention and Impact Yes This study examines the use of advance care planning on place of death and utilization of life-sustaining treatments among patients in end-of-life care. Yes Favorable The study found that patients with ACP were more likely to die at home and less likely to receive life-sustaining treatments during EOL care. BMJ Supportive & Palliative Care PubMed 33115830 10.1136/bmjspcare-2020-002520 https://pubmed.ncbi.nlm.nih.gov/33115830/
Interactions with the healthcare system influence advance care planning activities: Results from a representative survey in 11 developed countries Sable-Smith A, Arnett KR, Nowels MA, Colborn K, Lum HD, Nowels D. 2018 Other Linking Gap and Impact Yes N/A Yes Favorable The study found that individuals with greater interaction with the healthcare system through hospitalization, multimorbidity, access to quality primary care and informal caregiving reported more advance care planning activities. Family Practice PubMed 29140508 10.1093/fampra/cmx113 https://pubmed.ncbi.nlm.nih.gov/29140508/
Measuring decision aid effectiveness for end-of-life care: A systematic review Hughes MC, Vernon E, Egwuonwu C, Afolabi O. 2024 Systematic Review Linking Intervention and Impact Yes This is a systematic review analyzing the effectiveness of decision aids for end-of-life care. Yes Favorable The majority of studies reported positive outcomes in reducing decisional conflict in end of life care especially when the decision aid intervention was used. PEC Innovation PubMed 38525314 10.1016/j.pecinn.2024.100273 https://pubmed.ncbi.nlm.nih.gov/38525314/
Active choice intervention increases advance directive completion: A randomized trial Josephs M, Bayard D, Gabler NB, Cooney E, Halpern SD. 2018 Randomized Controlled Trial Linking Intervention and Impact Yes This study evaluates the effect of an active choice intervention on advance directive completion. Yes Favorable The intervention significantly increased the proportion of participants completing an advance directive without changing the choices in advance directive. MDM Policy & Practice PubMed 30288436 10.1177/2381468317753127 https://pubmed.ncbi.nlm.nih.gov/30288436/
Racial and ethnic differences in advance directive possession: Role of demographic factors, religious affiliation, and personal health values in a national survey of older adults Huang IA, Neuhaus JM, Chiong W. 2016 Other Linking Gap and Impact Yes N/A Yes Favorable The study found disparities in advance care planning, that black race is an independent predictor for advance directive possession. This association remains even after adjustment for other demographic variables, religious characteristics, and personal health values. Journal of Palliative Medicine PubMed 26840850  10.1089/jpm.2015.0326 https://pubmed.ncbi.nlm.nih.gov/26840850/
Self-determination and choice in the context of mental health services: Qualitative insights from a study of self-directed care Elizabeth C. Thomas, PhD, Yaara Zisman-Ilani, MA, PhD, and Mark S. Salzer, PhD 2019 Other Linking Gap and Impact Yes N/A Yes Favorable Self-directed care interventions should address competence, autonomy, and relatedness needs in order to facilitate choices that people with serious mental illnesses make as they work toward achieving recovery goals. Psychiatric Services PubMed PMC6718300 10.1176/appi.ps.201800544 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6718300/
Adding value to remote monitoring: Co-design of a health literacy intervention for older people with chronic disease delivered by telehealth - the telehealth literacy project Banbury A, Nancarrow S, Dart J, Gray L, Dodson S, Osborne R, Parkinson L. 2020 Other Linking Intervention and Impact Yes This study evaluates the effect of a health literacy, chronic disease self-management and social support intervention for older people delivered by group videoconferencing into the home. Yes Favorable The health literacy intervention indicates potential to improve social support and some health literacy factors in older people. Patient Education and Counseling PubMed 31744701 10.1016/j.pec.2019.10.005 https://pubmed.ncbi.nlm.nih.gov/31744701/
Advance directives and nursing home stays associated with less aggressive end-of-life care for patients with severe dementia Nicholas L, Bynum J PW, Iwashyna TJ, Weir D, Langa K. 2014 Other Linking Intervention and Impact Yes This study examines association between advance directives and nursing home stays and end-of-life care for patients with severe dementia Yes Dementia Favorable The study found that having an advance directive in the form of a living will was associated with significantly less aggressive care at the end of life, compared to similar patients without an advance directive. Health Affairs Google Scholar https://doi.org/10.1377/hlthaff.2013.1258 VIEW ARTICLE PERMISSIONS https://www.healthaffairs.org/doi/abs/10.1377/hlthaff.2013.1258
The value of advance care planning (ACP) in cancer critical care Portman DG, Lancet JE, Fernandez HF, Thirlwell S, Newman N. 2015 Other Linking Gap and Impact Yes N/A Cancer Favorable Among patients with advanced disease, obtaining timely advance directives with do-not-resuscitate is likely to result in the lowest daily cost of care for critical patients. Journal of Clinical Oncology Google Scholar https://doi.org/10.1200/jco.2015.33.15_suppl.e20557 https://ascopubs.org/doi/abs/10.1200/jco.2015.33.15_suppl.e20557
Advance directives and health disparities in lung cancer Blew AE 2017 Other Linking Gap and Impact Grey Literature N/A Yes Cancer Favorable The study found that documentation of living wills for lung cancer patients was low, especially among African Americans. N/A Google Scholar https://thescholarship.ecu.edu/handle/10342/6564
Health inequities in nursing home palliative and end-of-life care: A systematic review Estrada L, Agarwal M, Stone P 2022 Systematic Review Linking Gap and Impact Yes N/A Yes Favorable The study found numerous disparities in end of life care by race. White residents are more likely to complete advance directives compared to racial and ethnic minority residents. Black and Hispanic residents were less likely to convert from full care orders to do-not-resuscitate orders. Timely efforts are needed to improve NH end-of-life care by providing culturally competent training for NH staff that provide care in diverse NHs. Journal of Pain and Symptom Management Google Scholar https://doi.org/10.1016/j.jpainsymman.2022.02.049 https://www.sciencedirect.com/science/article/abs/pii/S0885392422001348?casa_token=MXvpzh0CoCEAAAAA:-zcCo7kfR_AtqrRirfiKu_VPBHqYZMyxYA8gzBb5tefYuaEhPLsQ0lxnv4Y_k5n5lscTwTvGPO09
Advance care planning for emergency department patients with COVID-19 infection: An assessment of a physician training program Casey MF, Price L, Markwalter D, Bohrmann T, Tsujimoto TM, Lavin K, Hanson LC, Lin FC, Platts-Mills TF. 2022 Other Linking Intervention and Impact Yes Observational study examining the effect of an educational program for emergency physicians on advance care planning conversations among patients in the emergency department during the COVID-19 pandemic. Patients received an advance care planning training toolkit and emergency departments physicians received an advance care planning educational session. Yes Favorable A quick and simple physician-facing educational intervention, though lacking in statistical significance, increased emergency department-based advance care planning activities for patients with COVID-19. American Journal of Hospice and Palliative Medicine PubMed 35040696 10.1177/10499091211072850 https://pubmed.ncbi.nlm.nih.gov/35040696/
Estimating the effect of palliative care interventions and advance care planning on icu utilization: A systematic review Khandelwal N, Kross EK, Engelberg RA, Coe NB, Long AC, Curtis JR. 2015 Systematic Review Linking Intervention and Impact Yes Systematic review examining effect of palliative care interventions and advance care planning on ICU utilization. Favorable Patients who received advance care planning or palliative care interventions consistently showed a pattern toward decreased ICU admissions and reduced ICU length of stay. Critical Care Medicine PubMed 25574794 10.1097/CCM.0000000000000852 https://pubmed.ncbi.nlm.nih.gov/25574794/
Effect of psychiatric advance directives facilitated by peer workers on compulsory admission among people with mental illness: A randomized clinical trial Tinland A, Loubière S, Mougeot F, Jouet E, Pontier M, Baumstarck K, Loundou A, Franck N, Lançon C, Auquier P; DAiP Group. 2022 Randomized Controlled Trial Linking Intervention and Impact Yes Study examining the effect of psychiatric advance directives facilitated by peer workers on compulsory hospital admissions among patients with mental illness. The intervention group completed a psychiatric advance directive form and met with a peer worker who was trained to assist in completing and sharing the form with relatives and psychiatrists. Favorable Peer worker-facilitated advance directives are effective in decreasing compulsory hospital admissions and increasing some mental health outcomes. JAMA Psychiatry PubMed 35662314 10.1001/jamapsychiatry.2022.1627 https://pubmed.ncbi.nlm.nih.gov/35662314/
Effect of an app for promoting advance care planning and motivating patients to write their advance directives Schöpfer C, Bollondi C, Moussa MA, Sommer J, Clavien C. 2023 Randomized Controlled Trial Linking Intervention and Impact Yes Study examining the effect of an app promoting advance care planning on patient motivation to write advance directives. Yes Favorable Overall, the intervention had a positive effect on the mean reported advance care planning engagement for all variables. BMC Health Services Research PubMed 37264350 10.1186/s12913-023-09593-3 https://pubmed.ncbi.nlm.nih.gov/37264350/
Implementation of an advance care planning inventory and its possible effect on quality of dying: A nationwide cross-sectional study in group homes for persons with dementia in Japan Takada S, Ogata Y, Yumoto Y, Ikeda M. 2021 Other Linking Intervention and Impact Yes This study examines the association between advance care planning inventory and its effect on quality of dying among individuals in group homes for persons with dementia. Yes Favorable The implementation of advance care planning improves the quality of dying. Healthcare PubMed 35052226 10.3390/healthcare10010062 https://pubmed.ncbi.nlm.nih.gov/35052226/
The impact of advance care planning on end-of-life care: Do the type and timing make a difference for patients with advanced cancer referred to hospice? Prater LC, Wickizer T, Bower JK, Bose-Brill S. 2019 Other Linking Intervention and Impact Yes This study examines the effect of advance care planning on potentially avoidable hospital admissions at the end of life among hospice-referred patients with cancer Yes Cancer Favorable The study found that dedicated advance care planning documentation is associated with fewer admissions in the last 30 days of life for patients with advanced cancer referred to hospice. American Journal of Hospice and Palliative Medicine PubMed 31088134 10.1177/1049909119848987 https://pubmed.ncbi.nlm.nih.gov/31088134/
The effect of end-of-life decision-making tools on patient and family-related outcomes of care among ethnocultural minorities: A systematic review Nayfeh A, Conn LG, Dale C, Kratina S, Hales B, Das Gupta T, Chakraborty A, Taggar R, Fowler R. 2022 Systematic Review Linking Intervention and Impact Yes This study examines the availability and effect of end of life decision-making tools on goals of care and advance care planning Yes Favorable Advance care planning programs, healthcare provider-led interventions and decision aids increased documentation of end-of-life care plans and do-not-resuscitate orders, and educational tools reduced preferences for life-prolonging care. PLoS One PubMed 35925996 10.1371/journal.pone.0272436 https://pubmed.ncbi.nlm.nih.gov/35925996/
Association of advance care planning visits with intensity of health care for medicare beneficiaries with serious illness at the end of life Weissman JS, Reich AJ, Prigerson HG, Gazarian P, Tjia J, Kim D, Rodgers P, Manful A. 2021 Prospective Cohort Study Linking Intervention and Impact Yes This study examines if billed advance care planning visits are associated with intensive use of health care services at the end of life. Yes Favorable Billed advance care planning services during the end of life of patients with serious illness were associated with less intensive use of end of life services. JAMA Health Forum PubMed 35977213 10.1001/jamahealthforum.2021.1829 https://pubmed.ncbi.nlm.nih.gov/35977213/
End-of-life planning depends on socio-economic and racial background: evidence from the US Health and Retirement Study (HRS) Orlovic M, Warraich H, Wolf D, Mossialos E. 2021 Other Linking Gap and Impact Yes N/A Yes Favorable End-of-life planning depends on several patient characteristics and circumstances, with socio-economic and racial/ethnic background having the largest effects. Understanding differences that increase end-of-life planning is important to incentivize patients' participation. Journal of Pain and Symptom Management PubMed 34062220 10.1016/j.jpainsymman.2021.05.018 https://pubmed.ncbi.nlm.nih.gov/34062220/
Advance care planning and patient preferences in a feasibility pilot study to improve end-of-life communication among men with metastatic urological malignancies Pannell SC, Laviana AA, Huen KHY, Shelton JB, Kwan L, Bennett CJ, Lorenz KA, Bergman J. 2018 Other Linking Intervention and Impact Yes This is a feasibility pilot study examining completion rate of an advance directive and patient preferences for end-of-life care among men in a urology palliative care clinic. Yes Cancer Favorable High levels of advance care planning are achievable, and the majority of patients with a terminal illness are averse to aggressive end of life care. Urology Practice PubMed 37312332 10.1016/j.urpr.2017.11.001 https://pubmed.ncbi.nlm.nih.gov/37312332/
Racial disparities of possessing healthcare power attorney and living will among older americans: Do SES and health matter? Lou Y, Liu J. 2021 Other Linking Gap and Impact Yes N/A Yes Favorable Older adults who only have power attorneys or only have living wills significantly differed in racial identity, socioeconomic status and health. Journal of Pain and Symptom Management PubMed 33484795 10.1016/j.jpainsymman.2021.01.004 https://pubmed.ncbi.nlm.nih.gov/33484795/
More older adults died at their preferred place after implementation of a transmural care pathway for older adults at the end of life: A before-after study van Doorne I, de Meij MA, Parlevliet JL, van Schie VMW, Willems DL, Buurman BM, van Rijn M. 2023 Other Linking Intervention and Impact Yes Before-after study examining changes in patient-related outcomes and transmural collaboration after implementation of the care pathway which involves timely identification of palliative care needs, advance care planning, multidisciplinary team meetings, warm handover, and follow-up home visits. Yes Favorable The intervention did not affect unplanned hospital admissions, however, more patients died at their place of preference after implementation. BMC Palliative Care PubMed 37533107  10.1186/s12904-023-01218-0 https://pubmed.ncbi.nlm.nih.gov/37533107/
Evaluation of a collaborative advance care planning intervention among older adult home health patients and their caregivers Tay DL, Ellington L, Towsley GL, Supiano K, Berg CA. 2020 Other Linking Intervention and Impact Yes This study used a questionnaire evaluating a theory-based advance care planning pilot intervention designed to improve decisional quality, readiness, collaboration, and concordance in advance care planning for older adult home health patients and caregivers Yes Favorable Results suggest that that collaborative advance care planning decision making may reduce decisional conflict between older adult patients and their caregivers. Journal of Palliative Medicine PubMed 32216645 https://doi.org/10.1089/jpm.2019.05 https://pubmed.ncbi.nlm.nih.gov/32216645/
Relationship between patient-centered care and advance care planning among home medical care patients in Japan: The Zaitaku evaluative initiatives and outcome study Hayashi S, Shirahige Y, Fujioka S, Tsugihashi Y, Iida H, Hirose M, Yasunaka M, Kurita N; ZEVIOUS Group. 2023 Other Linking Gap and Impact Yes N/A Yes Favorable The study found that lack of opportunities was the most common reason for not participating in advance care planning. Patient-centeredness in home medical care facilitates the initiation of advance care planning participation. Family Practice PubMed 35899787 10.1093/fampra/cmac062 https://pubmed.ncbi.nlm.nih.gov/35899787/
Association of advance directives completion with the utilization of life-sustaining treatments during the end-of-life care in older patients Yen YF, Huang LY, Hu HY, Sun WJ, Ko MC, Lee YL, Huang SJ, Chu D. 2018 Other Linking Gap and Impact Yes N/A Yes Favorable Advance directive completion was associated with a lower likelihood of receiving life-sustaining treatments during the last month of life in older patients. Journal of Pain and Symptom Management PubMed 28887268 10.1016/j.jpainsymman.2017.08.031 https://pubmed.ncbi.nlm.nih.gov/28887268/
Utilization of patient electronic messaging to promote advance care planning in the primary care setting Tieu C, Chaudhry R, Schroeder DR, Bock FA, Hanson GJ, Tung EE. 2017 Randomized Controlled Trial Linking Intervention and Impact Yes This study analyzes the effect of advance care planning-specific patient electronic messages on the rate of advance directive completion in older adults. Yes Favorable Among patients aged 65 years and older, use of advance directive-specific electronic messaging statistically significantly increased the rate of advance directive completion. American Journal of Hospice and Palliative Medicine PubMed 27188759  10.1177/1049909116650237 https://pubmed.ncbi.nlm.nih.gov/27188759/
Engaging diverse English- and Spanish-speaking older adults in advance care planning: The prepare randomized clinical trial Sudore RL, Schillinger D, Katen MT, Shi Y, Boscardin WJ, Osua S, Barnes DE. 2018 Randomized Controlled Trial Linking Intervention and Impact Yes Randomized clinical trial evaluating the effect of an online, easy-to-read, patient-directed advance care planning program on uptake of advance care planning among older adults. Yes Favorable The intervention may mitigate literacy and language barriers to advance care planning, allow patients to begin planning on their own, and could substantially improve the process for diverse English-speaking and Spanish-speaking populations. JAMA Internal Medicine PubMed 30383086 10.1001/jamainternmed.2018.4657 https://pubmed.ncbi.nlm.nih.gov/30383086/
Cancer patients spend more time at home and more often die at home with advance care planning conversations in primary health care: A retrospective observational cohort study Driller B, Talseth-Palmer B, Hole T, Strømskag KE, Brenne AT. 2022 Other Linking Gap and Impact Yes N/A Cancer Favorable Palliative cancer patients with a prior advance care planning conversation in primary health care spent more days at home and more frequently died at home. BMC Palliative Care PubMed 35501797 10.1186/s12904-022-00952-1 https://pubmed.ncbi.nlm.nih.gov/35501797/
The effectiveness of publicly available web-based interventions in promoting health app use, digital health literacy, and media literacy: Pre-post evaluation study König L, Suhr R. 2023 Other Linking Intervention and Impact Yes This study evaluates the effectiveness of web-based intervention designed to promote digital health and media literacy by teaching skills that enable users to distinguish trustworthiness of different health apps. Yes Favorable The intervention might promote the constructive use of health apps, digital health literacy, and media literacy and improved patient knowledge. Journal of Medical Internet Research PubMed 38048146 10.2196/46336 https://pubmed.ncbi.nlm.nih.gov/38048146/
Association between palliative care consultation and advance palliative care rates: A descriptive cohort study in patients at various stages in the continuum of chronic kidney disease Abdel-Rahman EM, Metzger M, Blackhall L, Asif M, Mamdouhi P, MacIntyre K, Casimir E, Ma JZ, Balogun RA. 2021 Other Linking Gap and Impact Yes N/A Yes End-Stage Renal Disease Favorable The study found that palliative care consultation is significantly associated with better end-of-life outcomes among patients with end-stage renal disease with more completion of ACP and hospice referral in patients. Journal of Palliative Medicine PubMed 32996797 10.1089/jpm.2020.0153 https://pubmed.ncbi.nlm.nih.gov/32996797/
Prevalence, content and significance of advance care planning in nursing home patients Kastbom L, Falk M, Karlsson M, Tengblad A, Milberg A. 2022 Other Linking Gap and Impact Yes This study uses a retrospective chart review on studies on advance care planning in nursing home settings. Yes Favorable Patients with care plans more frequently received prescriptions of palliative drugs and family members were better informed about the patient’s condition and impending death compared to those without care plans. Scandinavian Journal of Primary Health Care PubMed 35170393 10.1080/02813432.2022.2036429 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9090430/
Advance care planning: A systematic review of randomized controlled trials conducted with older adults Weathers E, O'Caoimh R, Cornally N, Fitzgerald C, Kearns T, Coffey A, Daly E, O'Sullivan R, McGlade C, Molloy DW. 2016 Systematic Review Linking Intervention and Impact Yes This study reviews the use of advance care planning with older adults across clinical settings. Yes Neutral Advance care planning interventions are well received by older adults and generally have positive effects on outcomes. Maturitas PubMed 27451328 10.1016/j.maturitas.2016.06.016 https://pubmed.ncbi.nlm.nih.gov/27451328/
The effects of advance care planning interventions on nursing home residents: A systematic review Martin RS, Hayes B, Gregorevic K, Lim WK. 2016 Systematic Review Linking Intervention and Impact Yes This study aims to determine the effect of advance care planning interventions on end of life outcomes in nursing home patients. Yes Favorable Advance care planning intervention increased the number of documented end-of-life care wishes but demonstrated no effect on satisfaction with end-of-life care from family caregivers' perspectives. International Journal of Nursing Studies PubMed 35667145 10.1016/j.ijnurstu.2022.104276 https://pubmed.ncbi.nlm.nih.gov/35667145/
A review of clinical trials of advance care planning interventions adapted for limited health literacy Houlihan MCK, Mayahara M, Swanson B, Fogg L. 2022 Other Linking Intervention and Impact Yes This study performs aa systematic review examining RCTs of advance care planning interventions adapted for limited health literacy. Yes Favorable Health literacy interventions increased participant knowledge, preference for comfort care, engagement, and care documentation. Palliative & Supportive Care PubMed 34446129 10.1017/S1478951521001152 https://pubmed.ncbi.nlm.nih.gov/34446129/
Advance directives and real-world end-of-life clinical practice: A case-control study Dalmau-Bueno A, Saura-Lazaro A, Busquets JM, Bullich-Marín I, García-Altés A. 2021 Other Linking Gap and Impact Yes N/A Yes Favorable Advance directives are an effective tool to adjust the occurrence of some procedures at the end of life and improve treatment plans. BMJ Supportive & Palliative Care PubMed 33753359 10.1136/bmjspcare-2020-002851 https://pubmed.ncbi.nlm.nih.gov/33753359/
Advance care planning in patients with primary malignant brain tumors: A systematic review Song K, Amatya B, Voutier C, Khan F. 2016 Systematic Review Linking Gap and Impact Yes This piece performs a systematic review examining studies of advance care planning in patients with primary malignant brain tumors. Favorable Positive effects of advance care planning included lower hospital readmission rates, and intensive care unit utilization. Frontiers in Oncology PubMed 27822458 10.3389/fonc.2016.00223 https://pubmed.ncbi.nlm.nih.gov/27822458/
Advance care planning, serious illness communication, and conversations to facilitate coping for patients with gastrointestinal malignancies: A narrative review Rao V, Guyer D, Almhanna K, Baum L. 2023 Other Linking Intervention and Impact Yes This is a narrative review examining advance care planning, serious illness communication, and conversations to facilitate coping for patients with gastrointestinal (GI) malignancies. Favorable Serious illness communication for future treatment has the potential to benefit patients with advanced GI malignancies in a variety of ways. Annals of Palliative Medicine PubMed 37574575 10.21037/apm-22-1261 https://pubmed.ncbi.nlm.nih.gov/37574575/
Comparison of web-based and paper advance directives: A pilot randomized clinical trial Rolnick JA, Oredeko F, Cooney-Zingman E, Asch DA, Halpern SD. 2021 Randomized Controlled Trial Linking Intervention and Impact Yes Patients with gastrointestinal and lung malignancies were randomized to the web or paper advance directives. Favorable Satisfaction with advance care planning and AD acceptability were high in both groups and not significantly different. Web-based advance directives hold promise for promoting documentation and sharing of preferences. American Journal of Hospice and Palliative Medicine PubMed 32648476 10.1177/1049909120940210 https://pubmed.ncbi.nlm.nih.gov/32648476/
Use of an ambulatory patient portal for advance care planning engagement Brungardt A, Daddato AE, Parnes B, Lum HD. 2019 Other Linking Intervention and Impact Yes The study was a geriatric clinic pilot of a multi-modal population-based outreach strategy for portal-based advance care planning tools.  Favorable Brief motivational messages about advance care planning via a patient portal is feasible and may increase advance care planning outcomes for older adults in primary care. Journal of American Board of Family Medicine PubMed 31704762 10.3122/jabfm.2019.06.190016 https://pubmed.ncbi.nlm.nih.gov/31704762/
Factors associated with living will among older persons receiving long-term care in Finland Andreasen P, Forma L, Pietilä I. 2023 Other Linking Gap and Impact Yes N/A Yes Favorable Preparedness for the future with a living will varies according to services and on individual level. Advance care planning may reduce inequalities in end-of-life care. Palliative Care & Social Practice PubMed 38033875 10.1177/26323524231212513 https://pubmed.ncbi.nlm.nih.gov/38033875/
Implementation of advance care planning decision aids for patients undergoing high-risk surgery: A field-testing study Yamamoto K, Kaido T, Yokoi T, Shimada G, Taketa T, Nakayama K. 2022 Other Linking Intervention and Impact Yes The intervention group received two patient decision aids that met the international criteria developed by the researchers for patients before surgery. Study participants were patients scheduled to be admitted to the intensive care unit after surgery at one acute care hospital in Japan and their families.  Favorable Patients reported that using the intervention provided an opportunity to share their thoughts with their families and inspired them to start mapping their life plans, and patients wanted to share and discuss their decision-making process with medical professionals after the surgery. BMC Palliative Care PubMed 36224540 10.1186/s12904-022-01068-2 https://pubmed.ncbi.nlm.nih.gov/36224540/
Does an advance care planning video help patients having surgery for cancer discuss their healthcare preferences with their surgeons? Aslakson RA, Isenberg SR, Crossnohere NL, Conca-Cheng AM, Moore M, Bhamidipati A, Mora S, Miller J, Pastorini C, Singh S, Swoboda S, Pawlik T, Volandes A, Bridges JFP, Smith TJ, Weiss M, Roter D. 2019 Randomized Controlled Trial Linking Intervention and Impact Yes Randomized controlled trial in which intervention group viewed an advance care planning video. Patients randomized to the control arm viewed an informational video about the hospital surgical program. Cancer Neutral Patients found the advance care planning video helpful, but it did not significantly change the nature of the patient–surgeon communication or the content of ACP in the preoperative patient–surgeon conversation. Patient Centered Outcomes Research Institute (PCORI) PubMed https://www.ncbi.nlm.nih.gov/books/NBK595848/
The acceptability and effect of a communication-based advance care planning program for older adults Jo M, Park M, Park EJ, Choi JY. 2021 Randomized Controlled Trial Linking Intervention and Impact Yes The intervention is a patient-centered advance care planning program with surrogates and a structured and guided discussion by home health care nurses as the trained interventionists.  Yes Favorable The outcomes of this study suggest that the intervention may have a potential improvement on end-of-life care decision making for older adults in South Korea. Journal of Hospice and Palliative Nursing PubMed 34185729 10.1097/NJH.0000000000000762 https://pubmed.ncbi.nlm.nih.gov/34185729/
How does ethnicity affect presence of advance care planning in care records for individuals with advanced disease? A mixed-methods systematic review Crooks J, Trotter S; Patient Public Involvement Consortium; Clarke G. 2023 Systematic Review Linking Gap and Impact Yes N/A Favorable There are differences in the presence of legal advance care planning across ethnic groups despite similar presence of informal end of life conversations. BMC Palliative Care PubMed 37062841 10.1186/s12904-023-01168-7 https://pubmed.ncbi.nlm.nih.gov/37062841/
The effect of a comprehensive dementia care management program on end-of-life care Jennings LA, Turner M, Keebler C, Burton CH, Romero T, Wenger NS, Reuben DB. 2019 Other Linking Intervention and Impact Yes This study describes end of life care preferences and acute care and hospice use for individuals in comprehensive dementia care management program. Dementia Favorable The study found that patients in a comprehensive dementia care comanagement program had high engagement in advance care planning, high rates of hospice use, and low acute care utilization near the end of life. Journal of the American Geriatrics Society PubMed 30675898 10.1111/jgs.15769 https://pubmed.ncbi.nlm.nih.gov/30675898/#:~:text=Enrollees%20in%20a%20comprehensive%20dementia%20care%20comanagement%20program,may%20improve%20end-of-life%20care%20for%20persons%20with%20dementia.
Empowering patients with the prepare advance care planning program results in reciprocal clinician communication Nouri S, Street RL Jr, Barnes DE, Shi Y, Volow AM, Li B, Alexander SC, Sudore RL. 2022 Other Linking Intervention and Impact Yes This study aims to determine whether PREPARE program increases clinician advance care planning communication. Yes Favorable The PREPARE program was associated with greater clinician supportive ACP communication with older adults compared with an AD alone. The effect was strongest among Spanish speakers and was mediated by active patient participation. The intervention helps patients be more engaged communicators, which in turn encourages clinicians to be more supportive of patients. Enhanced patient-clinician communication may reduce disparities in advance care planning. Journal of the American Geriatrics Society PubMed 34758115  10.1111/jgs.17540 https://pubmed.ncbi.nlm.nih.gov/34758115/
Implementation and effectiveness of a learning collaborative to improve palliative care for seriously ill hemodialysis patients Kurella Tamura M, Holdsworth L, Stedman M, Aldous A, Asch SM, Han J, Harbert G, Lorenz KA, Malcolm E, Nicklas A, Moss AH, Lupu DE. 2022 Other Linking Intervention and Impact Yes Study examining the effect of a learning collaborative between hemodialysis centers improvement of palliative care among hemodialysis patients.The learning collaborative involved learning sessions, communication skills training, and implementation support. Yes Favorable A learning collaborative for hemodialysis centers spanning the coronavirus pandemic was associated with adoption of serious illness screening and goals of care discussions as well as improved documentation of advance care planning for seriously ill patients. Clinical Journal of the American Society of Nephrology PubMed 36104084 10.2215/CJN.00090122 https://pubmed.ncbi.nlm.nih.gov/36104084/
Effect of advance care planning discussions with trained nurses in older adults with chronic diseases in Japan Okada H, Kiuchi T, Okuhara T, Kizawa Y. 2022 Other Linking Intervention and Impact Yes A non-randomized controlled trial evaluating the effect of advance care plannign discussions with providers on knowledge, advance care planning readiness, self effiacy, and quality of life. among chronically ill people aged 65 years and older. Yes Favorable The study found that older adults with chronic diseases can have better communication with their families and health care providers and a higher quality of life if they engage in advance care planning discussions with trained nurses at an early stage. Annals of Palliative Medicine PubMed 34775775  10.21037/apm-21-2161 https://pubmed.ncbi.nlm.nih.gov/34775775/
Randomized controlled trial of advance care planning video decision aid for the general population Kang E, Lee J, Choo J, Min J, Yun YH. 2020 Randomized Controlled Trial Linking Intervention and Impact Yes The intervention was a video that provided information about advance care planning and end-of-life care options such as cardiopulmonary resuscitation and palliative care. An attention-control arm was given a booklet about advance directives.  Favorable A well-constructed video decision support intervention can increased patients' intention to document advance care planning in the general population. Journal of Pain Symptom Management PubMed 31866488 10.1016/j.jpainsymman.2019.12.353 https://pubmed.ncbi.nlm.nih.gov/31866488/
Increasing advance care planning using a surgical optimization program for older adults Kata A, Sudore R, Finlayson E, Broering JM, Ngo S, Tang VL. 2018 Other Linking Intervention and Impact Yes Study examining the effect of a surgical optimization program on advance care planning uptake among older adults. In the surgical optimization program, participants received an advance care planning discussion with a provider, and trained medical and nurse practitioner students were used as health coaches who contacted participants regularly to address and document advance care planning. Yes Favorable Preoperative optimization programs provide a unique opportunity to engage older adults in advance care planning. Journal of the American Geriatrics Society PubMed 30289968 10.1111/jgs.15554 https://pubmed.ncbi.nlm.nih.gov/30289968/